ABIN1673168

antibody from antibodies-online

Targeting: STAT6 D12S1644, IL-4-STAT

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673168

Provider

antibodies-online

Product name

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (N-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the N-terminal of human Stat6, different from the related rat sequence by one amino acid and mouse sequence by two amino acids.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

N-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study.

Duetsch G, Illig T, Loesgen S, Rohde K, Klopp N, Herbon N, Gohlke H, Altmueller J, Wjst M
Human molecular genetics 2002 Mar 15;11(6):613-21

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Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium.

Mullings RE, Wilson SJ, Puddicombe SM, Lordan JL, Bucchieri F, Djukanović R, Howarth PH, Harper S, Holgate ST, Davies DE
The Journal of allergy and clinical immunology 2001 Nov;108(5):832-8

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Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression.

Dickensheets HL, Venkataraman C, Schindler U, Donnelly RP
Proceedings of the National Academy of Sciences of the United States of America 1999 Sep 14;96(19):10800-5