Tissue expression
Cell line expression
Protein structure

STAT6

Signal transducer and activator of transcription 6
D12S1644, IL-4-STAT 
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
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1628 antibodies from 51 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
82 antibodies
antibodies-online
535 antibodies
GeneTex
20 antibodies
NSJ Bioreagents
6 antibodies
Novus Biologicals
75 antibodies
Proteintech Group
3 antibodies
Boster Biological Technology
10 antibodies
Abnova Corporation
19 antibodies
Biorbyt
153 antibodies
Cell Signaling Technology, Inc
10 antibodies
Affinity Biosciences
4 antibodies
OriGene
36 antibodies
Cusabio Biotech Co., Ltd
16 antibodies
R&D Systems
24 antibodies
HUABIO Research
3 antibodies
BioLegend
22 antibodies
NovoPro Bioscience Inc.
8 antibodies
Abgent
7 antibodies
Bethyl Laboratories
3 antibodies
Signalway Antibody LLC
4 antibodies
Atlas Antibodies
1 antibody
St John's Laboratory
22 antibodies
Aviva Systems Biology
15 antibodies
Bioworld Technology, Inc
4 antibodies
Acris Antibodies GmbH
23 antibodies
FineTest Biotech
2 antibodies
Arigo
5 antibodies
ProSci
5 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
RabMAbs
5 antibodies
QED Bioscience
2 antibodies
Creative Diagnostics
5 antibodies
Abbexa
23 antibodies
MyBioSource
13 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Miltenyi Biotec
18 antibodies
United States Biological
121 antibodies
MilliporeSigma / Merck KGaA
11 antibodies
Sino Biological Inc.
5 antibodies
Spring Bioscience
4 antibodies
FabGennix
3 antibodies
GenWay
14 antibodies
EMD Millipore
5 antibodies
Leading Biology
3 antibodies
Abbiotec
2 antibodies
Abiocode, Inc.
1 antibody
Aladdin Scientific Corporation
1 antibody
Creative Biolabs
44 antibodies
RayBiotech, Inc.
3 antibodies