ABIN967241

antibody from antibodies-online

Targeting: VAV1 VAV

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN967241

Provider

antibodies-online

Product name

anti-Vav 1 Oncogene (VAV1) (pTyr174) antibody

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human Vav around the phosphorylation site of tyrosine 174 (E-I-YP-E-D).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100ug

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain.

Amarasinghe GK, Rosen MK
Biochemistry 2005 Nov 22;44(46):15257-68

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Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.

Charvet C, Canonigo AJ, Billadeau DD, Altman A
The Journal of biological chemistry 2005 Apr 15;280(15):15289-99

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Cbl-mediated ubiquitinylation and negative regulation of Vav.

Miura-Shimura Y, Duan L, Rao NL, Reddi AL, Shimura H, Rottapel R, Druker BJ, Tsygankov A, Band V, Band H
The Journal of biological chemistry 2003 Oct 3;278(40):38495-504

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A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation.

Kuhne MR, Ku G, Weiss A
The Journal of biological chemistry 2000 Jan 21;275(3):2185-90