VAV1

gene product
VAV
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
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555 antibodies from 38 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
antibodies-online
153 antibodies
Biorbyt
24 antibodies
Invitrogen Antibodies
6 antibodies
Novus Biologicals
42 antibodies
GeneTex
10 antibodies
NovoPro Bioscience Inc.
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Abnova Corporation
7 antibodies
R&D Systems
3 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
Affinity Biosciences
4 antibodies
Abgent
7 antibodies
LifeSpan BioSciences, Inc.
74 antibodies
OriGene
15 antibodies
Acris Antibodies GmbH
9 antibodies
Aviva Systems Biology
8 antibodies
SignalChem
1 antibody
Bioworld Technology, Inc
4 antibodies
Signalway Antibody LLC
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Boster Biological Technology
3 antibodies
Bethyl Laboratories
1 antibody
RabMAbs
5 antibodies
Abbkine Scientific Co.Ltd.
6 antibodies
Arigo
1 antibody
St John's Laboratory
9 antibodies
Creative Biolabs
5 antibodies
ProSci
3 antibodies
Abbexa
1 antibody
United States Biological
96 antibodies
MyBioSource
7 antibodies
Sigma-Aldrich
5 antibodies
Creative Diagnostics
2 antibodies
RayBiotech, Inc.
1 antibody
GenWay
3 antibodies
EMD Millipore
2 antibodies
Exalpha Biologicals, Inc.
1 antibody