2450

antibody from Cell Signaling Technology, Inc

Targeting: APP AD1

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

2450

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#2450, RRID:AB_490857

Product name

APP/β-Amyloid (NAB228) Mouse mAb

Antibody type

Monoclonal

Reactivity

Human, Bovine, Simian

Host

Mouse

Storage

-20°C

References

Submitted references

Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.

Lee EB, Leng LZ, Zhang B, Kwong L, Trojanowski JQ, Abel T, Lee VM
The Journal of biological chemistry 2006 Feb 17;281(7):4292-9

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BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo.

Lee EB, Zhang B, Liu K, Greenbaum EA, Doms RW, Trojanowski JQ, Lee VM
The Journal of cell biology 2005 Jan 17;168(2):291-302

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Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons.

Lee EB, Skovronsky DM, Abtahian F, Doms RW, Lee VM
The Journal of biological chemistry 2003 Feb 14;278(7):4458-66