Tissue expression
Cell line expression
Protein structure

APP

Amyloid beta precursor protein
AD1 
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
More gene data

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4794 antibodies from 54 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
206 antibodies
Invitrogen Antibodies
195 antibodies
Atlas Antibodies
1 antibody
antibodies-online
1114 antibodies
GeneTex
51 antibodies
Proteintech Group
5 antibodies
Abnova Corporation
85 antibodies
OriGene
157 antibodies
NSJ Bioreagents
11 antibodies
Biorbyt
499 antibodies
QED Bioscience
8 antibodies
St John's Laboratory
16 antibodies
Cell Signaling Technology, Inc
27 antibodies
Boster Biological Technology
7 antibodies
Aviva Systems Biology
40 antibodies
Cusabio Biotech Co., Ltd
20 antibodies
Affinity Biosciences
7 antibodies
Abgent
23 antibodies
R&D Systems
27 antibodies
Enzo Life Sciences
19 antibodies
Bioworld Technology, Inc
5 antibodies
BioLegend
46 antibodies
Acris Antibodies GmbH
78 antibodies
NovoPro Bioscience Inc.
15 antibodies
ProSci
14 antibodies
Aladdin Scientific Corporation
4 antibodies
FineTest Biotech
3 antibodies
Rockland Immunochemicals, Inc.
11 antibodies
Antibodies.com
3 antibodies
Signalway Antibody LLC
3 antibodies
RabMAbs
16 antibodies
Everest Biotech
1 antibody
Abbkine Scientific Co.Ltd.
4 antibodies
Creative Biolabs
686 antibodies
MilliporeSigma / Merck KGaA
27 antibodies
Absolute Antibody
27 antibodies
Creative Diagnostics
43 antibodies
MyBioSource
52 antibodies
EMD Millipore
46 antibodies
Kerafast Inc.
7 antibodies
BioLegend (formerly Covance Antibody Products)
43 antibodies
Abbiotec
15 antibodies
Abbexa
58 antibodies
GenWay
27 antibodies
United States Biological
251 antibodies
Spring Bioscience
8 antibodies
Leading Biology
26 antibodies
RayBiotech, Inc.
8 antibodies
DIMA
1 antibody
HUABIO Research
1 antibody
PhosphoSolutions
1 antibody