Tissue expression
Cell line expression
Protein structure

APP

Amyloid beta precursor protein
AD1 
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
More gene data

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5148 antibodies from 55 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
211 antibodies
Novus Biologicals
206 antibodies
Atlas Antibodies
1 antibody
Boster Biological Technology
7 antibodies
antibodies-online
1114 antibodies
GeneTex
51 antibodies
Proteintech Group
5 antibodies
Abnova Corporation
85 antibodies
OriGene
157 antibodies
NSJ Bioreagents
13 antibodies
Biorbyt
815 antibodies
QED Bioscience
8 antibodies
St John's Laboratory
16 antibodies
Cell Signaling Technology, Inc
27 antibodies
Aviva Systems Biology
40 antibodies
Cusabio Biotech Co., Ltd
20 antibodies
Affinity Biosciences
7 antibodies
Abgent
23 antibodies
R&D Systems
27 antibodies
Enzo Life Sciences
19 antibodies
Bioworld Technology, Inc
5 antibodies
BioLegend
46 antibodies
Acris Antibodies GmbH
78 antibodies
NovoPro Bioscience Inc.
15 antibodies
ProSci
14 antibodies
FineTest Biotech
3 antibodies
Rockland Immunochemicals, Inc.
11 antibodies
Antibodies.com
3 antibodies
Signalway Antibody LLC
3 antibodies
Aladdin Scientific
6 antibodies
Creative Biolabs
700 antibodies
RabMAbs
16 antibodies
Everest Biotech
1 antibody
Abbkine Scientific Co.Ltd.
4 antibodies
MilliporeSigma / Merck KGaA
27 antibodies
Absolute Antibody
27 antibodies
Creative Diagnostics
43 antibodies
MyBioSource
52 antibodies
EMD Millipore
46 antibodies
Kerafast Inc.
7 antibodies
BioLegend (formerly Covance Antibody Products)
43 antibodies
Abbiotec
15 antibodies
Abbexa
58 antibodies
GenWay
27 antibodies
United States Biological
251 antibodies
Spring Bioscience
8 antibodies
Leading Biology
26 antibodies
Mabtech
4 antibodies
RayBiotech, Inc.
8 antibodies
DIMA
1 antibody
HUABIO Research
1 antibody
PhosphoSolutions
1 antibody