APP

gene product
AD1
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
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3883 antibodies from 47 providers.

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Novus Biologicals
205 antibodies
antibodies-online
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GeneTex
51 antibodies
Boster Biological Technology
4 antibodies
Abnova Corporation
85 antibodies
OriGene
134 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
482 antibodies
Invitrogen Antibodies
57 antibodies
St John's Laboratory
13 antibodies
Biorbyt
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Cell Signaling Technology, Inc
25 antibodies
Rockland Immunochemicals, Inc.
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Aviva Systems Biology
40 antibodies
Affinity Biosciences
7 antibodies
NSJ Bioreagents
11 antibodies
Abgent
23 antibodies
R&D Systems
27 antibodies
Enzo Life Sciences
19 antibodies
Bioworld Technology, Inc
5 antibodies
BioLegend
36 antibodies
Acris Antibodies GmbH
78 antibodies
NovoPro Bioscience Inc.
15 antibodies
ProSci
14 antibodies
Antibodies.com
3 antibodies
Proteintech Group
2 antibodies
Signalway Antibody LLC
3 antibodies
Creative Biolabs
403 antibodies
RabMAbs
16 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
Sigma-Aldrich
19 antibodies
Absolute Antibody
6 antibodies
Creative Diagnostics
43 antibodies
MyBioSource
52 antibodies
EMD Millipore
46 antibodies
Everest Biotech
1 antibody
BioLegend (formerly Covance Antibody Products)
43 antibodies
Abbiotec
15 antibodies
GenWay
27 antibodies
United States Biological
251 antibodies
Spring Bioscience
8 antibodies
RayBiotech, Inc.
8 antibodies
PhosphoSolutions
1 antibody
Abbexa
6 antibodies
Exalpha Biologicals, Inc.
9 antibodies