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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [26]
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- Product number
- 25524-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- APP antibody
- Antibody type
- Polyclonal
- Description
- APP antibody (Cat. #25524-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway.
Isoorientin Affects Markers of Alzheimer's Disease via Effects on the Oral and Gut Microbiota in APP/PS1 Mice.
GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal.
Impaired Learning and Memory Ability Induced by a Bilaterally Hippocampal Injection of Streptozotocin in Mice: Involved With the Adaptive Changes of Synaptic Plasticity.
Comprehensive analysis of O-glycosylation of amyloid precursor protein (APP) using targeted and multi-fragmentation MS strategy.
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing.
The effects of antimony on Alzheimer's disease-like pathological changes in mice brain.
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma.
Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function.
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Bottom up proteomics identifies neuronal differentiation pathway networks activated by cathepsin inhibition treatment in neuroblastoma cells that are enhanced by concurrent 13-cis retinoic acid treatment.
N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy.
Tetramethylpyrazine Attenuated Sevoflurane-Induced Neurotoxicity by Enhancing Autophagy through GPR50/CREB Pathway in SH-SY5Y Cells.
Serum Exosomal Proteins F9 and TSP-1 as Potential Diagnostic Biomarkers for Newly Diagnosed Epilepsy.
Activating transcription factor 6 reduces Aβ1-42 and restores memory in Alzheimer's disease model mice.
A transcriptomic analysis of Nsmce1 overexpression in mouse hippocampal neuronal cell by RNA sequencing.
Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells.
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting.
Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35.
Shen Y, Li Y, Zhu Q, Wang J, Huang Y, Liang J, Wu X, Zhao Y
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63
Isoorientin Affects Markers of Alzheimer's Disease via Effects on the Oral and Gut Microbiota in APP/PS1 Mice.
Zhang Z, Tan X, Sun X, Wei J, Li QX, Wu Z
The Journal of nutrition 2022 Jan 11;152(1):140-152
The Journal of nutrition 2022 Jan 11;152(1):140-152
GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal.
Zhu Z, Liu Y, Li X, Zhang L, Liu H, Cui Y, Wang Y, Zhao D
Neuroscience letters 2022 Jan 10;767:136300
Neuroscience letters 2022 Jan 10;767:136300
Impaired Learning and Memory Ability Induced by a Bilaterally Hippocampal Injection of Streptozotocin in Mice: Involved With the Adaptive Changes of Synaptic Plasticity.
Qi CC, Chen XX, Gao XR, Xu JX, Liu S, Ge JF
Frontiers in aging neuroscience 2021;13:633495
Frontiers in aging neuroscience 2021;13:633495
Comprehensive analysis of O-glycosylation of amyloid precursor protein (APP) using targeted and multi-fragmentation MS strategy.
Shi J, Ku X, Zou X, Hou J, Yan W, Zhang Y
Biochimica et biophysica acta. General subjects 2021 Oct;1865(10):129954
Biochimica et biophysica acta. General subjects 2021 Oct;1865(10):129954
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Ma Y, Wang L, He F, Yang J, Ding Y, Ge S, Fan X, Zhou Y, Xu X, Jia R
Cancer letters 2021 May 28;506:67-82
Cancer letters 2021 May 28;506:67-82
Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing.
He K, Zhang J, Liu J, Cui Y, Liu LG, Ye S, Ban Q, Pan R, Liu D
Aging 2021 Mar 24;13(6):9011-9027
Aging 2021 Mar 24;13(6):9011-9027
The effects of antimony on Alzheimer's disease-like pathological changes in mice brain.
Xu S, Yang Z, Zhi Y, Yu S, Zhang T, Jiang J, Tang J, He H, Lu M, Wang X, Wu Q, Zhao X
The Science of the total environment 2021 Mar 15;760:143235
The Science of the total environment 2021 Mar 15;760:143235
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
Liu T, Li T, Chen X, Zhang K, Li M, Yao W, Zhang C, Wan L
Journal of ethnopharmacology 2021 Jun 28;274:114037
Journal of ethnopharmacology 2021 Jun 28;274:114037
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
Du H, Wong MY, Zhang T, Santos MN, Hsu C, Zhang J, Yu H, Luo W, Hu F
Life science alliance 2021 Jul;4(7)
Life science alliance 2021 Jul;4(7)
Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma.
Huo M, Yu K, Zheng Y, Liu L, Zhao H, Li X, Huang C, Zhang J
Bioscience reports 2021 Jul 30;41(7)
Bioscience reports 2021 Jul 30;41(7)
Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function.
Wang X, Zhu YT, Zhu Y, Sun YL, Huang J, Li Z, Wang Y, Wu JC, Qin ZH, Lin F
Acta pharmacologica Sinica 2021 Jul 16;
Acta pharmacologica Sinica 2021 Jul 16;
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z
Free radical biology & medicine 2021 Jan;162:181-190
Free radical biology & medicine 2021 Jan;162:181-190
Bottom up proteomics identifies neuronal differentiation pathway networks activated by cathepsin inhibition treatment in neuroblastoma cells that are enhanced by concurrent 13-cis retinoic acid treatment.
Halakos EG, Connell AJ, Glazewski L, Wei S, Mason RW
Journal of proteomics 2021 Feb 10;232:104068
Journal of proteomics 2021 Feb 10;232:104068
N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy.
Long CM, Zheng QX, Zhou Y, Liu YT, Gong LP, Zeng YC, Liu S
Journal of pharmacological sciences 2021 Dec;147(4):315-324
Journal of pharmacological sciences 2021 Dec;147(4):315-324
Tetramethylpyrazine Attenuated Sevoflurane-Induced Neurotoxicity by Enhancing Autophagy through GPR50/CREB Pathway in SH-SY5Y Cells.
Xu L, Shen J, Dai S, Sun L, Chen X
The American journal of Chinese medicine 2020;48(4):945-966
The American journal of Chinese medicine 2020;48(4):945-966
Serum Exosomal Proteins F9 and TSP-1 as Potential Diagnostic Biomarkers for Newly Diagnosed Epilepsy.
Lin Z, Gu Y, Zhou R, Wang M, Guo Y, Chen Y, Ma J, Xiao F, Wang X, Tian X
Frontiers in neuroscience 2020;14:737
Frontiers in neuroscience 2020;14:737
Activating transcription factor 6 reduces Aβ1-42 and restores memory in Alzheimer's disease model mice.
Du Y, Liu X, Zhu X, Liu Y, Wang X, Wu X
The International journal of neuroscience 2020 Oct;130(10):1015-1023
The International journal of neuroscience 2020 Oct;130(10):1015-1023
A transcriptomic analysis of Nsmce1 overexpression in mouse hippocampal neuronal cell by RNA sequencing.
Gong M, Wang Z, Liu Y, Li W, Ye S, Zhu J, Zhang H, Wang J, He K
Functional & integrative genomics 2020 May;20(3):459-470
Functional & integrative genomics 2020 May;20(3):459-470
Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells.
Gong M, Ye S, Li WX, Zhang J, Liu Y, Zhu J, Lv W, Zhang H, Wang J, Lu A, He K
American journal of physiology. Cell physiology 2020 Jun 1;318(6):C1123-C1135
American journal of physiology. Cell physiology 2020 Jun 1;318(6):C1123-C1135
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
Wei H, Zhang HL, Wang XC, Xie JZ, An DD, Wan L, Wang JZ, Zeng Y, Shu XJ, Westermarck J, Lu YM, Ohlmeyer M, Liu R
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Jul;17(3):1087-1103
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Jul;17(3):1087-1103
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Escande-Beillard N, Loh A, Saleem SN, Kanata K, Hashimoto Y, Altunoglu U, Metoska A, Grandjean J, Ng FM, Pomp O, Baburajendran N, Wong J, Hill J, Beillard E, Cozzone P, Zaki M, Kayserili H, Hamada H, Shiratori H, Reversade B
Neuron 2020 Jul 8;107(1):82-94.e6
Neuron 2020 Jul 8;107(1):82-94.e6
siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation.
Osana S, Kitajima Y, Suzuki N, Xu Y, Murayama K, Nagatomi R
Experimental cell research 2020 Dec 1;397(1):112337
Experimental cell research 2020 Dec 1;397(1):112337
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting.
Zhang Y, Xie JZ, Xu XY, Hu J, Xu T, Jin S, Yang SJ, Wang JZ
Neuroscience bulletin 2019 Aug;35(4):724-734
Neuroscience bulletin 2019 Aug;35(4):724-734
Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35.
Yan M, Mao S, Dong H, Liu B, Zhang Q, Pan G, Fu Z
Neural regeneration research 2012 Mar 25;7(9):652-8
Neural regeneration research 2012 Mar 25;7(9):652-8
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