Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [145]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 25524-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- APP antibody
- Antibody type
- Polyclonal
- Description
- APP antibody (Cat. #25524-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Flavonoids of Ziziphora clinopodioides improve Alzheimer's cognitive impairment and inhibit NLRP3 inflammasome activation via autophagy-lysosome pathway.
The effect of CysLTR1 inhibition on cells of the retinal neurovascular unit in 5xFAD Alzheimer mice.
Lingguizhugan decoction improves cognitive impairment in APP/PS1 mice by promoting meningeal lymphatic drainage based on fatty acid degradation pathway.
A Dual-Targeted Fluorescent Probe with a Semicurcumin Structure for Imaging β-Amyloid and α-Synuclein Aggregates.
ISX9 activates the Wnt/β-catenin signaling pathway and exerts neuroprotective effects in Alzheimer's disease.
Machine learning-guided Huanglian Jiedu decoction targets STING in periodontitis-induced Alzheimer's Disease.
Self-Assembled Rg3/Naringenin Nanoparticles for Targeted Brain Delivery: A Promising Therapeutic Approach for Early Alzheimer's Disease.
Targeting AARS1-dependent lactylation improves neuronal process plasticity and mitigates cognitive deficits in sepsis-associated encephalopathy.
Tianwang Buxin Pill improves cognitive function in APP/PS1 mice by reducing neuronal damage and regulating synaptic plasticity.
Baicalein alleviates Alzheimer's disease pathology in AD models by activating the PI3K/AKT/GSK3β pathway to inhibit neuronal apoptosis.
Olfactory Dysfunction Exacerbates Hippocampal Aβ Accumulation, Tau Phosphorylation and Memory Deficits in Mice.
Treponema pallidum Impairs Microglial Aβ(1)(-)(4)(2) Clearance by Hijacking TLR2/PI3K/AKT Immune Signaling.
The impact of high-intensity interval training on cerebrovascular function in the APP/PS1 mice.
Natural progression of meningeal lymphatic dysfunction in APP/PS1 mice creates a critical window for Alzheimer's disease intervention.
Overexpression of SFPQ Improves Cognition and Memory in AD Mice.
Impact of hyaluronic acid-modified hafnium metalorganic frameworks containing rhynchophylline on Alzheimer's disease.
Exploring the Kidney-Brain Crosstalk: Biomarkers for Early Detection of Kidney Injury-Related Alzheimer's Disease.
Dexmedetomidine ameliorates cognitive and affective deficits by modulating neuroinflammation and neurogenesis in an Alzheimer's disease mouse model.
Differential effects of Huang-Lian-Jie-Du Decoction on Alzheimer's disease and normal rats.
Late-Stage Activation of Toll-like receptor 3 Alleviates Cognitive Impairment and Neuropathology in an Alzheimer's Disease Mouse Model.
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria.
Improving neuronal recovery in spinal cord injury with NEP1-40-modified neural stem cells through RhoA/ROCK signaling pathway modulation.
Huang-Lian-Jie-Du decoction alleviates cognitive impairment in periodontitis rats through restoring microbiota-gut-brain axis and inhibiting neuroinflammation via TLR4/NF-κB pathway.
Downregulation of Nrf2 deteriorates cognitive impairment in APP/PS1 mice by inhibiting mitochondrial biogenesis through the PPARγ/PGC1α signaling pathway.
Cerebrovascular mechanisms between type 2 diabetes and Alzheimer's disease: Insights from ultrasound localization microscopy.
Myricetin Suppresses Inflammatory Th17 Polarization to Mitigate Alzheimer's Disease Pathogenesis.
Chuanxiong-Renshen medicine pair ameliorates neuroinflammation in Alzheimer's disease through modulation of the PKC-α/NF-κB signaling pathway.
ZuoGui Pill Ameliorates Alzheimer's Disease-Like Pathology in 3xTg-AD Mice by Targeting Aβ Production, Tau Phosphorylation, Synaptic Loss, and Neuroinflammation.
Aerobic exercise improves clearance of amyloid-β via the glymphatic system in a mouse model of Alzheimer's Disease.
Aflatoxin B1 exposure induces Alzheimer's disease like pathology by disrupting redox homeostasis and activating ferroptotic signals in C57BL/6 J mice.
Inhibition of PDE4B ameliorates cognitive defects in the model of alcoholic dementia in 3xTg-AD mice via PDE4B/cAMP/PKA signaling.
Jiajian Shuyu pills effectively ameliorate cognitive impairment via regulating the inflammation of microglia in an Alzheimer's disease mouse model.
Magnetic Levitational Assembly of Differentiated SH-SY5Y Cells for Aβ-Induced 3D Alzheimer's Disease Modeling and Curcumin Screening.
An integrative study on the effects of Lingguizhugan decoction in treating Alzheimer's disease rats through modulation of multiple pathways involving various components.
Integrated network pharmacology, metabolomics, and microbiome studies to reveal the therapeutic effects of Anacyclus pyrethrum in PD-MCI mice.
Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer's disease-like pathology and cognitive decline.
Computer-aided discovery of triazolothiadiazoles as DYRK1A-targeted neuroprotective agents.
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Etomidate ameliorates Alzheimer-like neuropathology and cognitive impairment in APP/PS1 mice.
Discovery of a novel DYRK1A inhibitor with neuroprotective activity by virtual screening and in vitro biological evaluation.
MLKL-USP7-UBA52 signaling is indispensable for autophagy in brain through maintaining ubiquitin homeostasis.
Network pharmacology study on the mechanism of berberine in Alzheimer's disease model.
GGC repeat expansions in NOTCH2NLC cause uN2CpolyG cerebral amyloid angiopathy.
Inflammatory signaling attenuates spliceosome function and cognitive ability.
Tat-NR2B9c prevent cognitive dysfunction in mice modeling Alzheimer's Disease induced by Aβ(1-42) via perturbing PSD-95 interactions with NR2B-subtype receptors.
Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer's Disease Agonist of PANK2.
Spatial Domain-Based Approach to Analyze the Mechanism of Sparganii Rhizoma-Curcumae Rhizoma Pair in the Treatment of Colorectal Cancer.
An Integrated Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and Experimental Validation Study to Investigate the Potential Mechanism of Isoliquiritigenin in the Treatment of Ischemic Stroke.
Virtual screening and fragment growth strategy for developing near-infrared fluorescent probes to detect Aβ in Alzheimer's disease model.
Melatonin alleviates retinal injury induced by vigabatrin and partially enhances its antiepileptic effects.
Investigating the Effect and Mechanism of 3-Methyladenine Against Diabetic Encephalopathy by Network Pharmacology, Molecular Docking, and Experimental Validation.
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
TLR4/Rac1/NLRP3 Pathway Mediates Amyloid-β-Induced Neuroinflammation in Alzheimer's Disease.
Chronic noise exposure induces Alzheimer's disease-like neuropathology and cognitive impairment via ferroptosis in rat hippocampus.
Dexmedetomidine Attenuated Neuron Death, Cognitive Decline, and Anxiety-Like Behavior by Inhibiting CXCL2 in CA1 Region of AD Mice.
Enhancement of cognitive function in mice with Alzheimer's disease through hyperbaric oxygen-induced activation of cellular autophagy.
Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice.
Maresin1 restrains chronic inflammation and Aβ production to ameliorate Alzheimer's disease via modulating ADAM10/17 and its associated neuroprotective signal pathways: A pilot study.
Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via the p53/SAT1/ALOX15 signalling pathway.
A new neuroprotective candidate TJ1 targeting amyloidogenesis in 5xFAD Alzheimer's disease mice.
Myeloid ectopic viral integration site 2 accelerates the progression of Alzheimer's disease.
Tetradecyl 2,3-Dihydroxybenzoate Improves Cognitive Function in AD Mice by Modulating Autophagy and Inflammation Through IPA and Hsc70 Targeting.
Bifidobacterium lactis-Derived Vesicles Attenuate Hippocampal Neuroinflammation by Targeting IL-33 to Regulate FoxO6/P53 Signaling.
Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system.
Neuroprotective effects of mesenchymal stromal cells in mouse models of Alzheimer's Disease: The Mediating role of gut microbes and their metabolites via the Microbiome-Gut-Brain axis.
Differential proteomic profiles of exosomes in pediatric and adult adamantinomatous craniopharyngioma cyst fluid.
Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice.
Total ginsenosides decrease Aβ production through activating PPARγ.
Neurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8(+) T cells in cerebral malaria.
The changes of neurogenesis in the hippocampal dentate gyrus of SAMP8 mice and the effects of acupuncture and moxibustion.
A Multisystemic Approach Revealed Aminated Polystyrene Nanoparticles-Induced Neurotoxicity.
Novel Social Stimulation Ameliorates Memory Deficit in Alzheimer's Disease Model through Activating α-Secretase.
Discovery of a novel chemotype as DYRK1A inhibitors against Alzheimer's disease: Computational modeling and biological evaluation.
Neuroprotective effects of Shenghui decoction via inhibition of the JNK/p38 MAPK signaling pathway in an AlCl(3)-induced zebrafish (Danio rerio) model of Alzheimer's disease.
Epigallocatechin-3-gallate Inhibits LPS/AβO-induced Neuroinflammation in BV2 Cells through Regulating the ROS/TXNIP/NLRP3 Pathway.
Chronic pain exacerbates memory impairment and pathology of Aβ and tau by upregulating IL-1β and p-65 signaling in a mouse model of Alzheimer's disease.
TaqTth-hpRNA: a novel compact RNA-targeting tool for specific silencing of pathogenic mRNA.
ApoE Mimic Peptide COG1410 Reduces Aβ Deposition and Improves Cognitive Function by Inducing the Transformation of A1/A2 Reactive Astrocytes and Increasing the BDNF Concentration in Brain of APP/PS1 Double Transgenic Mice.
Antioxidant Efficacy of Hwangryunhaedok-tang through Nrf2 and AMPK Signaling Pathway against Neurological Disorders In Vivo and In Vitro.
Age-dependent sex differences in cofilin1 pathway (LIMK1/SSH1) and its association with AD biomarkers after chronic systemic inflammation in mice.
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin.
FOLR2(+) macrophage depletion from intestinal metaplasia to early gastric cancer: single-cell sequencing insight into gastric cancer progression.
Protective effect of melatonin against metabolic disorders and neuropsychiatric injuries in type 2 diabetes mellitus mice.
Peripheral amyloid-β clearance mediates cognitive impairment in non-alcoholic fatty liver disease.
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer.
Electropositive Citric Acid-Polyethyleneimine Carbon Dots Carrying the PINK1 Gene Regulate ATP-Related Metabolic Dysfunction in APP/PS1-N2a Cells.
Suppression of hnRNP A1 binding to HK1 RNA leads to glycolytic dysfunction in Alzheimer's disease models.
A guide to selecting high-performing antibodies for amyloid-beta precursor protein for use in Western Blot, immunoprecipitation and immunofluorescence.
Rolipram Ameliorates Memory Deficits and Depression-Like Behavior in APP/PS1/tau Triple Transgenic Mice: Involvement of Neuroinflammation and Apoptosis via cAMP Signaling.
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.
Controlled release of Clenbuterol from a hydroxyapatite carrier for the treatment of Alzheimer's Disease.
Application of Dominant Gut Microbiota Promises to Replace Fecal Microbiota Transplantation as a New Treatment for Alzheimer's Disease.
Therapeutic Mechanism of Kai Xin San on Alzheimer's Disease Based on Network Pharmacology and Experimental Validation.
Depletion of gut microbiota resistance in 5×FAD mice enhances the therapeutic effect of mesenchymal stem cell-derived exosomes.
Gastrodin and Gastrodigenin Improve Energy Metabolism Disorders and Mitochondrial Dysfunction to Antagonize Vascular Dementia.
Reduced expression of APLP2 in spinal GABAergic inhibitory neurons contributed to nerve injury-induced microglial activation and pain sensitization.
miRNA-137-5p improves spatial memory and cognition in Alzheimer's mice by targeting ubiquitin-specific peptidase 30.
Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model.
Brain-targeted lycopene-loaded microemulsion modulates neuroinflammation, oxidative stress, apoptosis and synaptic plasticity in β-amyloid-induced Alzheimer's disease mice.
Transfer of Tumor-Bearing Mice Intestinal Flora Can Ameliorate Cognition in Alzheimer's Disease Mice.
Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats.
Activation of the RMTg Nucleus by Chemogenetic Techniques Alleviates the Learning and Memory Impairment in APP/PS1 Mice.
Involvement of Huanglian Jiedu Decoction on Microglia with Abnormal Sphingolipid Metabolism in Alzheimer's Disease.
Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation.
Resveratrol ameliorates learning and memory impairments induced by bilateral hippocampal injection of streptozotocin in mice.
Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway.
Effects of the Notch Signaling Pathway on Secondary Brain Changes Caused by Spinal Cord Injury in Mice.
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8(+) T cells.
Astragalin attenuates AlCl(3)/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation.
The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway.
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation.
Isoorientin Affects Markers of Alzheimer's Disease via Effects on the Oral and Gut Microbiota in APP/PS1 Mice.
GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal.
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology.
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Stem cells from human exfoliated deciduous teeth relieves Alzheimer's disease symptoms in SAMP8 mice by up-regulating the PPARγ pathway.
Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model.
Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function.
Brain-Penetration and Neuron-Targeting DNA Nanoflowers Co-Delivering miR-124 and Rutin for Synergistic Therapy of Alzheimer's Disease.
Investigating a Curcumin-Loaded PLGA-PEG-PLGA Thermo-Sensitive Hydrogel for the Prevention of Alzheimer's Disease.
Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis.
Impaired Learning and Memory Ability Induced by a Bilaterally Hippocampal Injection of Streptozotocin in Mice: Involved With the Adaptive Changes of Synaptic Plasticity.
Comprehensive analysis of O-glycosylation of amyloid precursor protein (APP) using targeted and multi-fragmentation MS strategy.
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing.
The effects of antimony on Alzheimer's disease-like pathological changes in mice brain.
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma.
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Bottom up proteomics identifies neuronal differentiation pathway networks activated by cathepsin inhibition treatment in neuroblastoma cells that are enhanced by concurrent 13-cis retinoic acid treatment.
Endogenous Aβ induces osteoporosis through an mTOR-dependent inhibition of autophagy in bone marrow mesenchymal stem cells (BMSCs).
N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy.
Tetramethylpyrazine Attenuated Sevoflurane-Induced Neurotoxicity by Enhancing Autophagy through GPR50/CREB Pathway in SH-SY5Y Cells.
Serum Exosomal Proteins F9 and TSP-1 as Potential Diagnostic Biomarkers for Newly Diagnosed Epilepsy.
Activating transcription factor 6 reduces Aβ1-42 and restores memory in Alzheimer's disease model mice.
A transcriptomic analysis of Nsmce1 overexpression in mouse hippocampal neuronal cell by RNA sequencing.
Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells.
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting.
Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35.
Gu L, Liu J, Shan X, Li S, Zheng M, Wang C, Tan Y, Zhuo X, Li Q, Yang W, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158028
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158028
The effect of CysLTR1 inhibition on cells of the retinal neurovascular unit in 5xFAD Alzheimer mice.
Mayr D, Preishuber-Pflügl J, Koller A, Migschitz SM, Michael J, Altendorfer B, Rabl R, Amschl D, Hitzl W, Aigner L, Reitsamer HA, Trost A
Experimental eye research 2026 Jan;262:110763
Experimental eye research 2026 Jan;262:110763
Lingguizhugan decoction improves cognitive impairment in APP/PS1 mice by promoting meningeal lymphatic drainage based on fatty acid degradation pathway.
Shen Z, Wu M, Sun S, Ling Y, Chen X, Zhang J, Zhou X, Zhou C
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120748
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120748
A Dual-Targeted Fluorescent Probe with a Semicurcumin Structure for Imaging β-Amyloid and α-Synuclein Aggregates.
Liang Z, Tang T, Wu J, Yang H, Zou Y, Dai J, Liu X, Yang J
Bioconjugate chemistry 2026 Jan 21;37(1):31-39
Bioconjugate chemistry 2026 Jan 21;37(1):31-39
ISX9 activates the Wnt/β-catenin signaling pathway and exerts neuroprotective effects in Alzheimer's disease.
Xiao J, Liu Y, Peng M, Ma J, Lei S, Chen Y, Liu S, Zhao X, Lu D, Sun Q
Alzheimer's research & therapy 2026 Feb 5;18(1)
Alzheimer's research & therapy 2026 Feb 5;18(1)
Machine learning-guided Huanglian Jiedu decoction targets STING in periodontitis-induced Alzheimer's Disease.
Li J, Chen M, Ren P, Sun G, Zhong F, Zhu Y, Li G, Fan Y, Chen J, Xu M, Qiao M, Zhao G, Xu Y, Wu W
NPJ digital medicine 2026 Feb 27;9(1)
NPJ digital medicine 2026 Feb 27;9(1)
Self-Assembled Rg3/Naringenin Nanoparticles for Targeted Brain Delivery: A Promising Therapeutic Approach for Early Alzheimer's Disease.
Lou X, Ni Z, Cui S, He Z, Zong Y, Chen W, Geng J, Zhou J, Li Z, Zhao Y, Teng H
Pharmaceuticals (Basel, Switzerland) 2026 Feb 26;19(3)
Pharmaceuticals (Basel, Switzerland) 2026 Feb 26;19(3)
Targeting AARS1-dependent lactylation improves neuronal process plasticity and mitigates cognitive deficits in sepsis-associated encephalopathy.
Luo S, Lyu Z, Huang H, Zhao J, Li Y, Luo Y
Brain, behavior, and immunity 2026 Feb 17;135:106493
Brain, behavior, and immunity 2026 Feb 17;135:106493
Tianwang Buxin Pill improves cognitive function in APP/PS1 mice by reducing neuronal damage and regulating synaptic plasticity.
Zou F, Ren X, Huo G, Liu P, Sun C
Journal of ethnopharmacology 2026 Aug 10;367:121683
Journal of ethnopharmacology 2026 Aug 10;367:121683
Baicalein alleviates Alzheimer's disease pathology in AD models by activating the PI3K/AKT/GSK3β pathway to inhibit neuronal apoptosis.
Cheng W, Yang S, Lu Y, Wang Y, Tan AH
Scientific reports 2026 Apr 4;
Scientific reports 2026 Apr 4;
Olfactory Dysfunction Exacerbates Hippocampal Aβ Accumulation, Tau Phosphorylation and Memory Deficits in Mice.
Du M, Ma S, Bai L, Mou X, Gao Y, Zhang J, Chen Y
Neurochemical research 2026 Apr 3;51(2)
Neurochemical research 2026 Apr 3;51(2)
Treponema pallidum Impairs Microglial Aβ(1)(-)(4)(2) Clearance by Hijacking TLR2/PI3K/AKT Immune Signaling.
Xie L, Ke JL, Hu YT, Ma FQ, Zheng MX, Wang RY, Yan Y, Lin YY, Liu LL
ACS infectious diseases 2026 Apr 10;12(4):1329-1337
ACS infectious diseases 2026 Apr 10;12(4):1329-1337
The impact of high-intensity interval training on cerebrovascular function in the APP/PS1 mice.
Zhu L, Cai M, Lu Z, Wang Q, Zhai T, Hu J
Frontiers in aging 2025;6:1647628
Frontiers in aging 2025;6:1647628
Natural progression of meningeal lymphatic dysfunction in APP/PS1 mice creates a critical window for Alzheimer's disease intervention.
Shen Z, Zhou X, He L, Wu M, Zhou C
Turkish journal of medical sciences 2025;55(6):1576-1583
Turkish journal of medical sciences 2025;55(6):1576-1583
Overexpression of SFPQ Improves Cognition and Memory in AD Mice.
Tie J, Wu H, Liu W, Li Y, Li L, Zhao S, Yuan Z, Mahmood K, Chen S, Wu H
Neural plasticity 2025;2025:3934591
Neural plasticity 2025;2025:3934591
Impact of hyaluronic acid-modified hafnium metalorganic frameworks containing rhynchophylline on Alzheimer's disease.
Lin S, Ye Y, Lin S
Open life sciences 2025;20(1):20221043
Open life sciences 2025;20(1):20221043
Exploring the Kidney-Brain Crosstalk: Biomarkers for Early Detection of Kidney Injury-Related Alzheimer's Disease.
Cai Y, Huang G, Ren M, Chai Y, Fu Y, Yan T, Zhu L
Journal of inflammation research 2025;18:827-846
Journal of inflammation research 2025;18:827-846
Dexmedetomidine ameliorates cognitive and affective deficits by modulating neuroinflammation and neurogenesis in an Alzheimer's disease mouse model.
Li M, An C, Wang X, Ren M, Liu S, Chen R, Guo Y, Wang J, Fei Y, Ma D, Ma K, Zhang Y
Frontiers in aging neuroscience 2025;17:1724739
Frontiers in aging neuroscience 2025;17:1724739
Differential effects of Huang-Lian-Jie-Du Decoction on Alzheimer's disease and normal rats.
Xu M, Zhu Y, Chen J, Zhong F, Wang R, Li J, Qiao M, Fan Y, Ren P, Chen M, Qin J, Wu W
Frontiers in pharmacology 2025;16:1710919
Frontiers in pharmacology 2025;16:1710919
Late-Stage Activation of Toll-like receptor 3 Alleviates Cognitive Impairment and Neuropathology in an Alzheimer's Disease Mouse Model.
Zhu T, Shen F, Jia X, Zhou H, Ni W, Wang S, Wu D, Gao H, Shang Z, Zhou Y, Han J, Jin G, Dong F, Zu J, Yang X, Shi H, Zhou C, Hua F
Molecular neurobiology 2025 Oct;62(10):12616-12633
Molecular neurobiology 2025 Oct;62(10):12616-12633
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria.
Wang J, Zhu Q, Tong G, Yu K, Liang J, Huang Y, Wang Y, Yang C, Li T, Liang W, Li G, Liu X, Sun J, Li Y, Shen Y, Zhao Y
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2385-2400
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2385-2400
Improving neuronal recovery in spinal cord injury with NEP1-40-modified neural stem cells through RhoA/ROCK signaling pathway modulation.
Gu W, Zhang X, Yuan X, Cao D, Zhao H, Hu J, Yuan H
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167929
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167929
Huang-Lian-Jie-Du decoction alleviates cognitive impairment in periodontitis rats through restoring microbiota-gut-brain axis and inhibiting neuroinflammation via TLR4/NF-κB pathway.
Chen M, Li J, Ren P, Yang S, Zhong F, Zhu Y, Fan Y, Chen J, Xu M, Wu W
Chinese medicine 2025 Oct 23;20(1):179
Chinese medicine 2025 Oct 23;20(1):179
Downregulation of Nrf2 deteriorates cognitive impairment in APP/PS1 mice by inhibiting mitochondrial biogenesis through the PPARγ/PGC1α signaling pathway.
Luo W, Bu W, Zhang G, Dong Y, Wang Y, Wang J, Liu C, Hu X, Jia Y, Ren H
Behavioural brain research 2025 Oct 18;495:115805
Behavioural brain research 2025 Oct 18;495:115805
Cerebrovascular mechanisms between type 2 diabetes and Alzheimer's disease: Insights from ultrasound localization microscopy.
Ren X, Zhang G, Zhou B, Gu W, Zhu Q, Liu X
Medical physics 2025 Nov;52(11):e70131
Medical physics 2025 Nov;52(11):e70131
Myricetin Suppresses Inflammatory Th17 Polarization to Mitigate Alzheimer's Disease Pathogenesis.
Li Y, Sun A, Han J, Hong R, Cao C, Zhou A, Fan Z, Zhang L, Qu X
CNS neuroscience & therapeutics 2025 Nov;31(11):e70644
CNS neuroscience & therapeutics 2025 Nov;31(11):e70644
Chuanxiong-Renshen medicine pair ameliorates neuroinflammation in Alzheimer's disease through modulation of the PKC-α/NF-κB signaling pathway.
Wang XY, Wang YY, Zhang J, Li Q, Yu T, Yang YX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157161
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157161
ZuoGui Pill Ameliorates Alzheimer's Disease-Like Pathology in 3xTg-AD Mice by Targeting Aβ Production, Tau Phosphorylation, Synaptic Loss, and Neuroinflammation.
Li S, Wang D, Li A, Wang T, Chen X, Li H, Wang T, Xie Y, Liang J, Cai X
Molecular neurobiology 2025 Nov 20;63(1):96
Molecular neurobiology 2025 Nov 20;63(1):96
Aerobic exercise improves clearance of amyloid-β via the glymphatic system in a mouse model of Alzheimer's Disease.
Liang S, Liu H, Wang X, Lin H, Zheng L, Zhang Y, Peng L, Huang S, Chen L
Brain research bulletin 2025 Mar;222:111263
Brain research bulletin 2025 Mar;222:111263
Aflatoxin B1 exposure induces Alzheimer's disease like pathology by disrupting redox homeostasis and activating ferroptotic signals in C57BL/6 J mice.
Lin J, Hong H, Liu S, Liang Z, Zheng Q, Luo K, Li J, Du Z, Yu J, Yang L, Deng P, Pi H, Yu Z, Yuan W, Zhou Z
The Science of the total environment 2025 Mar 20;970:179049
The Science of the total environment 2025 Mar 20;970:179049
Inhibition of PDE4B ameliorates cognitive defects in the model of alcoholic dementia in 3xTg-AD mice via PDE4B/cAMP/PKA signaling.
Sun R, Han M, Lin Y, Ma S, Tu H, Yang X, Zhang F, Zhang HT
The international journal of neuropsychopharmacology 2025 Mar 20;28(3)
The international journal of neuropsychopharmacology 2025 Mar 20;28(3)
Jiajian Shuyu pills effectively ameliorate cognitive impairment via regulating the inflammation of microglia in an Alzheimer's disease mouse model.
Chen Y, Zhu Y, Tan Z, Zhang X, Hu J, Zhu R, Xie M, Wang J, Chen L, Guo Z
Journal of ethnopharmacology 2025 Mar 13;343:119508
Journal of ethnopharmacology 2025 Mar 13;343:119508
Magnetic Levitational Assembly of Differentiated SH-SY5Y Cells for Aβ-Induced 3D Alzheimer's Disease Modeling and Curcumin Screening.
Bilginer-Kartal R, Arslan-Yildiz A
Macromolecular bioscience 2025 Jun;25(6):e2400658
Macromolecular bioscience 2025 Jun;25(6):e2400658
An integrative study on the effects of Lingguizhugan decoction in treating Alzheimer's disease rats through modulation of multiple pathways involving various components.
Wang Z, Zhang HT, Li SY, Song XP, Shi CZ, Zhang YW, Han F
Computers in biology and medicine 2025 Jun;191:110149
Computers in biology and medicine 2025 Jun;191:110149
Integrated network pharmacology, metabolomics, and microbiome studies to reveal the therapeutic effects of Anacyclus pyrethrum in PD-MCI mice.
Tuersong T, Wu QF, Chen Y, Shan Li P, Yong YX, Shataer M, Shataer S, Ma LY, Yang XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156729
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156729
Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer's disease-like pathology and cognitive decline.
Kong L, Li J, Gao L, Zhao Y, Chen W, Wang X, Wang S, Wang F
Alzheimer's research & therapy 2025 Jul 19;17(1):166
Alzheimer's research & therapy 2025 Jul 19;17(1):166
Computer-aided discovery of triazolothiadiazoles as DYRK1A-targeted neuroprotective agents.
Si X, Wang Y, Qiu N, Qian C, Yang B, Jin H, Wang H, Zhang X, Xia J
RSC medicinal chemistry 2025 Jul 14;16(10):4731-41
RSC medicinal chemistry 2025 Jul 14;16(10):4731-41
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Hu Z, Yang J, Zhang S, Li M, Zuo C, Mao C, Zhang Z, Tang M, Shi C, Xu Y
Neural regeneration research 2025 Jan 1;20(1):253-264
Neural regeneration research 2025 Jan 1;20(1):253-264
Etomidate ameliorates Alzheimer-like neuropathology and cognitive impairment in APP/PS1 mice.
Liu H, Zhou J, Yang WW
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2025 Feb;76(1)
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2025 Feb;76(1)
Discovery of a novel DYRK1A inhibitor with neuroprotective activity by virtual screening and in vitro biological evaluation.
Si X, Qian C, Qiu N, Wang Y, Yao M, Wang H, Zhang X, Xia J
Molecular diversity 2025 Feb;29(1):337-350
Molecular diversity 2025 Feb;29(1):337-350
MLKL-USP7-UBA52 signaling is indispensable for autophagy in brain through maintaining ubiquitin homeostasis.
Zhang Z, Chen S, Jun S, Xu X, Hong Y, Yang X, Zou L, Song YQ, Chen Y, Tu J
Autophagy 2025 Feb;21(2):424-446
Autophagy 2025 Feb;21(2):424-446
Network pharmacology study on the mechanism of berberine in Alzheimer's disease model.
Zhang Y, Lv S, Huang P, Xiao L, Lin N, Huang E
NPJ science of food 2025 Feb 4;9(1):16
NPJ science of food 2025 Feb 4;9(1):16
GGC repeat expansions in NOTCH2NLC cause uN2CpolyG cerebral amyloid angiopathy.
Bao L, Li X, Tian J, Wang L, Ji Y, Cui Y, Sun W, Zhang J, Xia M, Zhu P, Cui G, Chen H
Brain : a journal of neurology 2025 Feb 3;148(2):467-479
Brain : a journal of neurology 2025 Feb 3;148(2):467-479
Inflammatory signaling attenuates spliceosome function and cognitive ability.
Lin L, Huang X, Huang C, Zou J, Hu M, Lan T, Wang H, Du Z, Tian M, Liu J, Dong H, Liu B, Cheng H, Zhou L, Chen Y, Zhou R
Autophagy 2025 Dec;21(12):3123-3141
Autophagy 2025 Dec;21(12):3123-3141
Tat-NR2B9c prevent cognitive dysfunction in mice modeling Alzheimer's Disease induced by Aβ(1-42) via perturbing PSD-95 interactions with NR2B-subtype receptors.
Huang Y, Lei W, Shen J, Sun J
IBRO neuroscience reports 2025 Dec;19:317-322
IBRO neuroscience reports 2025 Dec;19:317-322
Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer's Disease Agonist of PANK2.
Chen Y, Ma H, Jin M, Zhang S, Qu S, Wang G, Aa J
Pharmaceuticals (Basel, Switzerland) 2025 Dec 9;18(12)
Pharmaceuticals (Basel, Switzerland) 2025 Dec 9;18(12)
Spatial Domain-Based Approach to Analyze the Mechanism of Sparganii Rhizoma-Curcumae Rhizoma Pair in the Treatment of Colorectal Cancer.
Liu YJ, Ye QW, Jin YL, Zhang Q, Zou X, Li JP
Food science & nutrition 2025 Aug;13(8):e70794
Food science & nutrition 2025 Aug;13(8):e70794
An Integrated Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and Experimental Validation Study to Investigate the Potential Mechanism of Isoliquiritigenin in the Treatment of Ischemic Stroke.
Yuan H, Hou Y, Jiao Y, Lu X, Liu L
Current issues in molecular biology 2025 Aug 6;47(8)
Current issues in molecular biology 2025 Aug 6;47(8)
Virtual screening and fragment growth strategy for developing near-infrared fluorescent probes to detect Aβ in Alzheimer's disease model.
Xu G, Zhou C, Su G, Liang Z, Wu J, Tang T, Bian Y, Cai J, Zou Y, Yang J
European journal of medicinal chemistry 2025 Aug 5;292:117695
European journal of medicinal chemistry 2025 Aug 5;292:117695
Melatonin alleviates retinal injury induced by vigabatrin and partially enhances its antiepileptic effects.
Ma M, Fan M, Xu S, Zheng Q, Wang C, Chen P, Wei Y, Ge J
International immunopharmacology 2025 Apr 24;153:114516
International immunopharmacology 2025 Apr 24;153:114516
Investigating the Effect and Mechanism of 3-Methyladenine Against Diabetic Encephalopathy by Network Pharmacology, Molecular Docking, and Experimental Validation.
Chu J, Song J, Fan Z, Zhang R, Wang Q, Yi K, Gong Q, Liu B
Pharmaceuticals (Basel, Switzerland) 2025 Apr 22;18(5)
Pharmaceuticals (Basel, Switzerland) 2025 Apr 22;18(5)
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Fan M, Jiang Y, Cai C, Wang Z, Chen L, Hu S, Zhang X, Yin H, Qian Z, Huang S, Yang J
Phytotherapy research : PTR 2025 Apr 17;
Phytotherapy research : PTR 2025 Apr 17;
TLR4/Rac1/NLRP3 Pathway Mediates Amyloid-β-Induced Neuroinflammation in Alzheimer's Disease.
Zhu M, Liu Y, Chen C, Chen H, Ni W, Song Y, Lv B, Hua F, Cui G, Zhang Z
Journal of Alzheimer's disease : JAD 2024;99(3):911-925
Journal of Alzheimer's disease : JAD 2024;99(3):911-925
Chronic noise exposure induces Alzheimer's disease-like neuropathology and cognitive impairment via ferroptosis in rat hippocampus.
Ma J, Zhang J, Ou Z, Ren Y, Wu K, Zhang Y, Chen S, Wang Z
Environmental health and preventive medicine 2024;29:50
Environmental health and preventive medicine 2024;29:50
Dexmedetomidine Attenuated Neuron Death, Cognitive Decline, and Anxiety-Like Behavior by Inhibiting CXCL2 in CA1 Region of AD Mice.
Ma K, An C, Li M, Zhang Y, Ren M, Wei Y, Xu W, Wang R, Bai Y, Zhang H, Liu X, Ji S, Chen X, Zhu K
Drug design, development and therapy 2024;18:5351-5365
Drug design, development and therapy 2024;18:5351-5365
Enhancement of cognitive function in mice with Alzheimer's disease through hyperbaric oxygen-induced activation of cellular autophagy.
Fan QQ, Chen YM, Fu YS, Li XS, Zeng J, Bian SZ, Li BB, Song ZH
Frontiers in aging neuroscience 2024;16:1418081
Frontiers in aging neuroscience 2024;16:1418081
Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice.
Zou Y, Wang C, Li H, Zhong M, Lin J, Hu Y, Chen Z, Gan CL
Frontiers in pharmacology 2024;15:1500105
Frontiers in pharmacology 2024;15:1500105
Maresin1 restrains chronic inflammation and Aβ production to ameliorate Alzheimer's disease via modulating ADAM10/17 and its associated neuroprotective signal pathways: A pilot study.
Sun S, Zhang T, Liu L, Zhou H, Yin P, Wang L
Archives of biochemistry and biophysics 2024 Sep;759:110109
Archives of biochemistry and biophysics 2024 Sep;759:110109
Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via the p53/SAT1/ALOX15 signalling pathway.
Ren X, Wen Y, Yuan M, Li C, Zhang J, Li S, Zhang X, Wang L, Wang S
European journal of pharmacology 2024 Sep 15;979:176820
European journal of pharmacology 2024 Sep 15;979:176820
A new neuroprotective candidate TJ1 targeting amyloidogenesis in 5xFAD Alzheimer's disease mice.
Deng JL, Huang LF, Bian ZY, Feng XY, Qi RY, Dong WX, Gao JM, Tang JJ
International immunopharmacology 2024 Sep 10;138:112653
International immunopharmacology 2024 Sep 10;138:112653
Myeloid ectopic viral integration site 2 accelerates the progression of Alzheimer's disease.
Cui Y, Zhang X, Liu J, Hou Y, Song Q, Cao M, Zhang J, Wang X, Liu C, Wang P, Wang Y
Aging cell 2024 Oct;23(10):e14260
Aging cell 2024 Oct;23(10):e14260
Tetradecyl 2,3-Dihydroxybenzoate Improves Cognitive Function in AD Mice by Modulating Autophagy and Inflammation Through IPA and Hsc70 Targeting.
Fasina OB, Li L, Chen D, Yi M, Xiang L, Qi J
International journal of molecular sciences 2024 Oct 31;25(21)
International journal of molecular sciences 2024 Oct 31;25(21)
Bifidobacterium lactis-Derived Vesicles Attenuate Hippocampal Neuroinflammation by Targeting IL-33 to Regulate FoxO6/P53 Signaling.
Du X, Zhang M, Wang R, Zeng Z, Zhao W, Fang B, Lan H, Hung W, Gao H
Nutrients 2024 Oct 22;16(21)
Nutrients 2024 Oct 22;16(21)
Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system.
Li K, Feng Z, Xiong Z, Pan J, Zhou M, Li W, Ou Y, Wu G, Che M, Gong H, Peng J, Wang X, Qi S, Peng J
Neural regeneration research 2024 Oct 1;19(10):2249-2258
Neural regeneration research 2024 Oct 1;19(10):2249-2258
Neuroprotective effects of mesenchymal stromal cells in mouse models of Alzheimer's Disease: The Mediating role of gut microbes and their metabolites via the Microbiome-Gut-Brain axis.
Xing C, Zhang X, Wang D, Chen H, Gao X, Sun C, Guo W, Roshan S, Li Y, Hang Z, Cai S, Lei T, Bi W, Hou L, Li L, Wu Y, Li L, Zeng Z, Du H
Brain, behavior, and immunity 2024 Nov;122:510-526
Brain, behavior, and immunity 2024 Nov;122:510-526
Differential proteomic profiles of exosomes in pediatric and adult adamantinomatous craniopharyngioma cyst fluid.
Chen Y, Wang Z, Huang Q, Wang Y, Yan F, Xiang S, Xu L, Chen Y, Liu X, Chen G, Li M, Zhou Y
Molecular biology reports 2024 Nov 7;51(1):1126
Molecular biology reports 2024 Nov 7;51(1):1126
Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice.
Liu X, Chen P, Wu W, Zhong M, Dong S, Lin H, Dai C, Zhang Z, Lin S, Che C, Xu J, Li C, Li H, Pan X, Chen Z, Chen X, Ye ZC
Life sciences 2024 Nov 15;357:123085
Life sciences 2024 Nov 15;357:123085
Total ginsenosides decrease Aβ production through activating PPARγ.
He S, Shi J, Ma L, Pei H, Zhang P, Shi D, Li H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116577
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116577
Neurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8(+) T cells in cerebral malaria.
Wang Y, Shen Y, Liang J, Wang S, Huang Y, Zhu Q, Zhang X, Yu K, Tong G, Yang C, Li Y, Wang J, Zhao Y
Journal of neuroinflammation 2024 May 7;21(1):119
Journal of neuroinflammation 2024 May 7;21(1):119
The changes of neurogenesis in the hippocampal dentate gyrus of SAMP8 mice and the effects of acupuncture and moxibustion.
Liu X, Chen J, Du Y, Tian Q, Wang L, Li W, Liu G, Tan Q, Wang J, Deng X
Brain research 2024 May 15;1831:148814
Brain research 2024 May 15;1831:148814
A Multisystemic Approach Revealed Aminated Polystyrene Nanoparticles-Induced Neurotoxicity.
Schröter L, Jentsch L, Maglioni S, Muñoz-Juan A, Wahle T, Limke A, von Mikecz A, Laromaine A, Ventura N
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(10):e2302907
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(10):e2302907
Novel Social Stimulation Ameliorates Memory Deficit in Alzheimer's Disease Model through Activating α-Secretase.
Ren Q, Wang S, Li J, Cao K, Zhuang M, Wu M, Geng J, Jia Z, Xie W, Liu A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Mar 20;44(12)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Mar 20;44(12)
Discovery of a novel chemotype as DYRK1A inhibitors against Alzheimer's disease: Computational modeling and biological evaluation.
Qiu N, Qian C, Guo T, Wang Y, Jin H, Yao M, Li M, Guo T, Lv Y, Si X, Wu S, Wang H, Zhang X, Xia J
International journal of biological macromolecules 2024 Jun;269(Pt 1):132024
International journal of biological macromolecules 2024 Jun;269(Pt 1):132024
Neuroprotective effects of Shenghui decoction via inhibition of the JNK/p38 MAPK signaling pathway in an AlCl(3)-induced zebrafish (Danio rerio) model of Alzheimer's disease.
Lu H, Tan A, Zhang Y, Chen Y, Ran S, Wang P
Journal of ethnopharmacology 2024 Jun 28;328:117993
Journal of ethnopharmacology 2024 Jun 28;328:117993
Epigallocatechin-3-gallate Inhibits LPS/AβO-induced Neuroinflammation in BV2 Cells through Regulating the ROS/TXNIP/NLRP3 Pathway.
Xiao Y, Yang C, Si N, Chu T, Yu J, Yuan X, Chen XT
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Jun 18;19(1):31
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Jun 18;19(1):31
Chronic pain exacerbates memory impairment and pathology of Aβ and tau by upregulating IL-1β and p-65 signaling in a mouse model of Alzheimer's disease.
Wang W, Zheng WQ, Du X, Chen SC, Chen YH, Ma QY, Wang H, Gao S, Tan R, Zhang HT, Zhou YM, Zhang FF
Brain research 2024 Jun 1;1832:148843
Brain research 2024 Jun 1;1832:148843
TaqTth-hpRNA: a novel compact RNA-targeting tool for specific silencing of pathogenic mRNA.
Xu C, Cao J, Qiang H, Liu Y, Wu J, Luo Q, Wan M, Wang Y, Wang P, Cheng Q, Zhou G, Sima J, Guo Y, Xu S
Genome biology 2024 Jul 7;25(1):179
Genome biology 2024 Jul 7;25(1):179
ApoE Mimic Peptide COG1410 Reduces Aβ Deposition and Improves Cognitive Function by Inducing the Transformation of A1/A2 Reactive Astrocytes and Increasing the BDNF Concentration in Brain of APP/PS1 Double Transgenic Mice.
Qiao Y, Liu H, He C, Ma Y
Neuroscience 2024 Jan 26;537:116-125
Neuroscience 2024 Jan 26;537:116-125
Antioxidant Efficacy of Hwangryunhaedok-tang through Nrf2 and AMPK Signaling Pathway against Neurological Disorders In Vivo and In Vitro.
Bae SJ, Lee WY, Bak SB, Lee SJ, Hwang SJ, Kim GW, Koo BS, Park SD, Yoo HH, Kim CO, Kang HW, Oh TW, Kim YW
International journal of molecular sciences 2024 Feb 15;25(4)
International journal of molecular sciences 2024 Feb 15;25(4)
Age-dependent sex differences in cofilin1 pathway (LIMK1/SSH1) and its association with AD biomarkers after chronic systemic inflammation in mice.
Alsegiani AS, Shah ZA
Neurobiology of aging 2024 Dec;144:43-55
Neurobiology of aging 2024 Dec;144:43-55
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Yang Y, Wu J, Jia L, Feng S, Qi Z, Yu H, Wu Y, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin.
Sun H, Gao X, Niu J, Chen P, He S, Xu S, Ge J
eNeuro 2024 Dec;11(12)
eNeuro 2024 Dec;11(12)
FOLR2(+) macrophage depletion from intestinal metaplasia to early gastric cancer: single-cell sequencing insight into gastric cancer progression.
He Y, Wang J, Deng Z, Feng H, Du M, Zhang D, Zhang G, Shi T, Chen W
Journal of experimental & clinical cancer research : CR 2024 Dec 19;43(1):326
Journal of experimental & clinical cancer research : CR 2024 Dec 19;43(1):326
Protective effect of melatonin against metabolic disorders and neuropsychiatric injuries in type 2 diabetes mellitus mice.
Gao X, Sun H, Wei Y, Niu J, Hao S, Sun H, Tang G, Qi C, Ge J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155805
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155805
Peripheral amyloid-β clearance mediates cognitive impairment in non-alcoholic fatty liver disease.
Peng X, Zhang X, Xu Z, Li L, Mo X, Peng Z, Shan Z, Yan H, Xu J, Liu L
EBioMedicine 2024 Apr;102:105079
EBioMedicine 2024 Apr;102:105079
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer.
Tan X, Wang S, Xiao GY, Wu C, Liu X, Zhou B, Jiang Y, Duose DY, Xi Y, Wang J, Gupta K, Pataer A, Roth JA, Kim MP, Chen F, Creighton CJ, Russell WK, Kurie JM
The Journal of clinical investigation 2024 Apr 25;134(12)
The Journal of clinical investigation 2024 Apr 25;134(12)
Electropositive Citric Acid-Polyethyleneimine Carbon Dots Carrying the PINK1 Gene Regulate ATP-Related Metabolic Dysfunction in APP/PS1-N2a Cells.
Yu S, Guo F, Luo Y, Zhang X, Wang C, Liu Y, Zhang H
Molecules (Basel, Switzerland) 2024 Apr 23;29(9)
Molecules (Basel, Switzerland) 2024 Apr 23;29(9)
Suppression of hnRNP A1 binding to HK1 RNA leads to glycolytic dysfunction in Alzheimer's disease models.
Ji XH, Liu TT, Wei AH, Lei HP, Chen Y, Wu LN, Liu J, Zhang Y, Yan F, Chen MX, Jin H, Shi JS, Zhou SY, Jin F
Frontiers in aging neuroscience 2023;15:1218267
Frontiers in aging neuroscience 2023;15:1218267
A guide to selecting high-performing antibodies for amyloid-beta precursor protein for use in Western Blot, immunoprecipitation and immunofluorescence.
Ayoubi R, Fotouhi M, Worrall D, Southern K, Laflamme C, NeuroSGC/YCharOS/EDDU collaborative group, ABIF consortium
F1000Research 2023;12:956
F1000Research 2023;12:956
Rolipram Ameliorates Memory Deficits and Depression-Like Behavior in APP/PS1/tau Triple Transgenic Mice: Involvement of Neuroinflammation and Apoptosis via cAMP Signaling.
Cong YF, Liu FW, Xu L, Song SS, Shen XR, Liu D, Hou XQ, Zhang HT
The international journal of neuropsychopharmacology 2023 Sep 25;26(9):585-598
The international journal of neuropsychopharmacology 2023 Sep 25;26(9):585-598
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.
Guo Y, Zhang L
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673
Controlled release of Clenbuterol from a hydroxyapatite carrier for the treatment of Alzheimer's Disease.
Lin YW, Fang CH, Liang YJ, Yang CY, Kuo WT, Lin FH
Biomaterials research 2023 Oct 5;27(1):98
Biomaterials research 2023 Oct 5;27(1):98
Application of Dominant Gut Microbiota Promises to Replace Fecal Microbiota Transplantation as a New Treatment for Alzheimer's Disease.
Li M, Yang H, Shao C, Liu Y, Wen S, Tang L
Microorganisms 2023 Nov 24;11(12)
Microorganisms 2023 Nov 24;11(12)
Therapeutic Mechanism of Kai Xin San on Alzheimer's Disease Based on Network Pharmacology and Experimental Validation.
Wang K, Yang R, Chen TT, Qin MR, Wang P, Kong MW
Chinese journal of integrative medicine 2023 May;29(5):413-423
Chinese journal of integrative medicine 2023 May;29(5):413-423
Depletion of gut microbiota resistance in 5×FAD mice enhances the therapeutic effect of mesenchymal stem cell-derived exosomes.
Hou X, Jiang H, Liu T, Yan J, Zhang F, Zhang X, Zhao J, Mu X, Jiang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114455
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114455
Gastrodin and Gastrodigenin Improve Energy Metabolism Disorders and Mitochondrial Dysfunction to Antagonize Vascular Dementia.
Wu S, Huang R, Zhang R, Xiao C, Wang L, Luo M, Song N, Zhang J, Yang F, Liu X, Yang W
Molecules (Basel, Switzerland) 2023 Mar 13;28(6)
Molecules (Basel, Switzerland) 2023 Mar 13;28(6)
Reduced expression of APLP2 in spinal GABAergic inhibitory neurons contributed to nerve injury-induced microglial activation and pain sensitization.
Li YZ, Zhu YB, Ge AN, Gao M, Wang KL, Zeng XR, Li J, Li Y, Xu JY, Bai HH, Wu SJ
Neuropharmacology 2023 Feb 15;224:109334
Neuropharmacology 2023 Feb 15;224:109334
miRNA-137-5p improves spatial memory and cognition in Alzheimer's mice by targeting ubiquitin-specific peptidase 30.
Jiang Y, Bian W, Chen J, Cao X, Dong C, Xiao Y, Xu B, Sun X
Animal models and experimental medicine 2023 Dec;6(6):526-536
Animal models and experimental medicine 2023 Dec;6(6):526-536
Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model.
Ding Y, Li L, Wang S, Cao Y, Yang M, Dai Y, Lin H, Li J, Liu Y, Wang Z, Liu W, Tao J
Biological research 2023 Dec 2;56(1):65
Biological research 2023 Dec 2;56(1):65
Brain-targeted lycopene-loaded microemulsion modulates neuroinflammation, oxidative stress, apoptosis and synaptic plasticity in β-amyloid-induced Alzheimer's disease mice.
Guo Y, Fan Z, Zhao S, Yu W, Hou X, Nie S, Xu S, Zhao C, Han J, Liu X
Neurological research 2023 Aug;45(8):753-764
Neurological research 2023 Aug;45(8):753-764
Transfer of Tumor-Bearing Mice Intestinal Flora Can Ameliorate Cognition in Alzheimer's Disease Mice.
Hang Z, Cai S, Lei T, Zhang X, Xiao Z, Wang D, Li Y, Bi W, Yang Y, Deng S, Wang L, Li Q, Du H
Journal of Alzheimer's disease : JAD 2022;86(3):1287-1300
Journal of Alzheimer's disease : JAD 2022;86(3):1287-1300
Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats.
Fan R, Dai F, Zhang C, Zhou L, Qiu X, Li Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2112359
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2112359
Activation of the RMTg Nucleus by Chemogenetic Techniques Alleviates the Learning and Memory Impairment in APP/PS1 Mice.
Zheng L, Wang Z, Liu Y, Zhao J, Huang S
Neuropsychiatric disease and treatment 2022;18:2957-2965
Neuropsychiatric disease and treatment 2022;18:2957-2965
Involvement of Huanglian Jiedu Decoction on Microglia with Abnormal Sphingolipid Metabolism in Alzheimer's Disease.
Qi YY, Heng X, Yao ZY, Qu SY, Ge PY, Zhao X, Ni SJ, Guo R, Yang NY, Zhang QC, Zhu HX
Drug design, development and therapy 2022;16:931-950
Drug design, development and therapy 2022;16:931-950
Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation.
Fan M, Liu S, Sun HM, Ma MD, Gao YJ, Qi CC, Xia QR, Ge JF
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113375
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113375
Resveratrol ameliorates learning and memory impairments induced by bilateral hippocampal injection of streptozotocin in mice.
Wei YD, Chen XX, Yang LJ, Gao XR, Xia QR, Qi CC, Ge JF
Neurochemistry international 2022 Oct;159:105385
Neurochemistry international 2022 Oct;159:105385
Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway.
Yao Y, Ren Z, Yang R, Mei Y, Dai Y, Cheng Q, Xu C, Xu X, Wang S, Kim KM, Noh JH, Zhu J, Zhao N, Liu YU, Mao G, Sima J
Cell & bioscience 2022 Nov 4;12(1):180
Cell & bioscience 2022 Nov 4;12(1):180
Effects of the Notch Signaling Pathway on Secondary Brain Changes Caused by Spinal Cord Injury in Mice.
Li C, Huang S, Zhou W, Xie Z, Xie S, Li M
Neurochemical research 2022 Jun;47(6):1651-1663
Neurochemical research 2022 Jun;47(6):1651-1663
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8(+) T cells.
Liang J, Shen Y, Wang Y, Huang Y, Wang J, Zhu Q, Tong G, Yu K, Cao W, Wang Q, Li Y, Zhao Y
Molecular brain 2022 Jun 20;15(1):57
Molecular brain 2022 Jun 20;15(1):57
Astragalin attenuates AlCl(3)/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation.
Hu Y, Fang X, Wang J, Ren TT, Zhao YY, Dai JF, Qin XY, Lan R
Neurotoxicology 2022 Jul;91:60-68
Neurotoxicology 2022 Jul;91:60-68
The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway.
Shen Y, Li Y, Zhu Q, Wang J, Huang Y, Liang J, Wu X, Zhao Y
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation.
Li L, Li WJ, Zheng XR, Liu QL, Du Q, Lai YJ, Liu SQ
Molecular medicine (Cambridge, Mass.) 2022 Jan 29;28(1):11
Molecular medicine (Cambridge, Mass.) 2022 Jan 29;28(1):11
Isoorientin Affects Markers of Alzheimer's Disease via Effects on the Oral and Gut Microbiota in APP/PS1 Mice.
Zhang Z, Tan X, Sun X, Wei J, Li QX, Wu Z
The Journal of nutrition 2022 Jan 11;152(1):140-152
The Journal of nutrition 2022 Jan 11;152(1):140-152
GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal.
Zhu Z, Liu Y, Li X, Zhang L, Liu H, Cui Y, Wang Y, Zhao D
Neuroscience letters 2022 Jan 10;767:136300
Neuroscience letters 2022 Jan 10;767:136300
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology.
Liu S, Fan M, Xu JX, Yang LJ, Qi CC, Xia QR, Ge JF
Journal of neuroinflammation 2022 Feb 7;19(1):35
Journal of neuroinflammation 2022 Feb 7;19(1):35
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Han QJ, Han G, Peng J, Tang Z
Free radical biology & medicine 2022 Feb 1;179:416-417
Free radical biology & medicine 2022 Feb 1;179:416-417
Stem cells from human exfoliated deciduous teeth relieves Alzheimer's disease symptoms in SAMP8 mice by up-regulating the PPARγ pathway.
Zhang X, Lei T, Wang D, Cai S, Hang Z, Yang Y, Bi W, Xiao Z, Du H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113169
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113169
Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model.
Tang JJ, Huang LF, Deng JL, Wang YM, Guo C, Peng XN, Liu Z, Gao JM
Redox biology 2022 Apr;50:102229
Redox biology 2022 Apr;50:102229
Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function.
Wang X, Zhu YT, Zhu Y, Sun YL, Huang J, Li Z, Wang Y, Wu JC, Qin ZH, Lin F
Acta pharmacologica Sinica 2022 Apr;43(4):850-861
Acta pharmacologica Sinica 2022 Apr;43(4):850-861
Brain-Penetration and Neuron-Targeting DNA Nanoflowers Co-Delivering miR-124 and Rutin for Synergistic Therapy of Alzheimer's Disease.
Ouyang Q, Liu K, Zhu Q, Deng H, Le Y, Ouyang W, Yan X, Zhou W, Tong J
Small (Weinheim an der Bergstrasse, Germany) 2022 Apr;18(14):e2107534
Small (Weinheim an der Bergstrasse, Germany) 2022 Apr;18(14):e2107534
Investigating a Curcumin-Loaded PLGA-PEG-PLGA Thermo-Sensitive Hydrogel for the Prevention of Alzheimer's Disease.
Lin YW, Fang CH, Yang CY, Liang YJ, Lin FH
Antioxidants (Basel, Switzerland) 2022 Apr 7;11(4)
Antioxidants (Basel, Switzerland) 2022 Apr 7;11(4)
Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis.
Cai Y, Chai Y, Fu Y, Wang Y, Zhang Y, Zhang X, Zhu L, Miao M, Yan T
Frontiers in aging neuroscience 2021;13:809433
Frontiers in aging neuroscience 2021;13:809433
Impaired Learning and Memory Ability Induced by a Bilaterally Hippocampal Injection of Streptozotocin in Mice: Involved With the Adaptive Changes of Synaptic Plasticity.
Qi CC, Chen XX, Gao XR, Xu JX, Liu S, Ge JF
Frontiers in aging neuroscience 2021;13:633495
Frontiers in aging neuroscience 2021;13:633495
Comprehensive analysis of O-glycosylation of amyloid precursor protein (APP) using targeted and multi-fragmentation MS strategy.
Shi J, Ku X, Zou X, Hou J, Yan W, Zhang Y
Biochimica et biophysica acta. General subjects 2021 Oct;1865(10):129954
Biochimica et biophysica acta. General subjects 2021 Oct;1865(10):129954
LACTB suppresses melanoma progression by attenuating PP1A and YAP interaction.
Ma Y, Wang L, He F, Yang J, Ding Y, Ge S, Fan X, Zhou Y, Xu X, Jia R
Cancer letters 2021 May 28;506:67-82
Cancer letters 2021 May 28;506:67-82
Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing.
He K, Zhang J, Liu J, Cui Y, Liu LG, Ye S, Ban Q, Pan R, Liu D
Aging 2021 Mar 24;13(6):9011-9027
Aging 2021 Mar 24;13(6):9011-9027
The effects of antimony on Alzheimer's disease-like pathological changes in mice brain.
Xu S, Yang Z, Zhi Y, Yu S, Zhang T, Jiang J, Tang J, He H, Lu M, Wang X, Wu Q, Zhao X
The Science of the total environment 2021 Mar 15;760:143235
The Science of the total environment 2021 Mar 15;760:143235
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
Liu T, Li T, Chen X, Zhang K, Li M, Yao W, Zhang C, Wan L
Journal of ethnopharmacology 2021 Jun 28;274:114037
Journal of ethnopharmacology 2021 Jun 28;274:114037
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
Du H, Wong MY, Zhang T, Santos MN, Hsu C, Zhang J, Yu H, Luo W, Hu F
Life science alliance 2021 Jul;4(7)
Life science alliance 2021 Jul;4(7)
Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma.
Huo M, Yu K, Zheng Y, Liu L, Zhao H, Li X, Huang C, Zhang J
Bioscience reports 2021 Jul 30;41(7)
Bioscience reports 2021 Jul 30;41(7)
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z
Free radical biology & medicine 2021 Jan;162:181-190
Free radical biology & medicine 2021 Jan;162:181-190
Bottom up proteomics identifies neuronal differentiation pathway networks activated by cathepsin inhibition treatment in neuroblastoma cells that are enhanced by concurrent 13-cis retinoic acid treatment.
Halakos EG, Connell AJ, Glazewski L, Wei S, Mason RW
Journal of proteomics 2021 Feb 10;232:104068
Journal of proteomics 2021 Feb 10;232:104068
Endogenous Aβ induces osteoporosis through an mTOR-dependent inhibition of autophagy in bone marrow mesenchymal stem cells (BMSCs).
Lin Y, Chen T, Chen J, Fang Y, Zeng C
Annals of translational medicine 2021 Dec;9(24):1794
Annals of translational medicine 2021 Dec;9(24):1794
N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy.
Long CM, Zheng QX, Zhou Y, Liu YT, Gong LP, Zeng YC, Liu S
Journal of pharmacological sciences 2021 Dec;147(4):315-324
Journal of pharmacological sciences 2021 Dec;147(4):315-324
Tetramethylpyrazine Attenuated Sevoflurane-Induced Neurotoxicity by Enhancing Autophagy through GPR50/CREB Pathway in SH-SY5Y Cells.
Xu L, Shen J, Dai S, Sun L, Chen X
The American journal of Chinese medicine 2020;48(4):945-966
The American journal of Chinese medicine 2020;48(4):945-966
Serum Exosomal Proteins F9 and TSP-1 as Potential Diagnostic Biomarkers for Newly Diagnosed Epilepsy.
Lin Z, Gu Y, Zhou R, Wang M, Guo Y, Chen Y, Ma J, Xiao F, Wang X, Tian X
Frontiers in neuroscience 2020;14:737
Frontiers in neuroscience 2020;14:737
Activating transcription factor 6 reduces Aβ1-42 and restores memory in Alzheimer's disease model mice.
Du Y, Liu X, Zhu X, Liu Y, Wang X, Wu X
The International journal of neuroscience 2020 Oct;130(10):1015-1023
The International journal of neuroscience 2020 Oct;130(10):1015-1023
A transcriptomic analysis of Nsmce1 overexpression in mouse hippocampal neuronal cell by RNA sequencing.
Gong M, Wang Z, Liu Y, Li W, Ye S, Zhu J, Zhang H, Wang J, He K
Functional & integrative genomics 2020 May;20(3):459-470
Functional & integrative genomics 2020 May;20(3):459-470
Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells.
Gong M, Ye S, Li WX, Zhang J, Liu Y, Zhu J, Lv W, Zhang H, Wang J, Lu A, He K
American journal of physiology. Cell physiology 2020 Jun 1;318(6):C1123-C1135
American journal of physiology. Cell physiology 2020 Jun 1;318(6):C1123-C1135
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
Wei H, Zhang HL, Wang XC, Xie JZ, An DD, Wan L, Wang JZ, Zeng Y, Shu XJ, Westermarck J, Lu YM, Ohlmeyer M, Liu R
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Jul;17(3):1087-1103
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Jul;17(3):1087-1103
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Escande-Beillard N, Loh A, Saleem SN, Kanata K, Hashimoto Y, Altunoglu U, Metoska A, Grandjean J, Ng FM, Pomp O, Baburajendran N, Wong J, Hill J, Beillard E, Cozzone P, Zaki M, Kayserili H, Hamada H, Shiratori H, Reversade B
Neuron 2020 Jul 8;107(1):82-94.e6
Neuron 2020 Jul 8;107(1):82-94.e6
siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation.
Osana S, Kitajima Y, Suzuki N, Xu Y, Murayama K, Nagatomi R
Experimental cell research 2020 Dec 1;397(1):112337
Experimental cell research 2020 Dec 1;397(1):112337
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting.
Zhang Y, Xie JZ, Xu XY, Hu J, Xu T, Jin S, Yang SJ, Wang JZ
Neuroscience bulletin 2019 Aug;35(4):724-734
Neuroscience bulletin 2019 Aug;35(4):724-734
Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35.
Yan M, Mao S, Dong H, Liu B, Zhang Q, Pan G, Fu Z
Neural regeneration research 2012 Mar 25;7(9):652-8
Neural regeneration research 2012 Mar 25;7(9):652-8
No comments: Submit comment
No validations: Submit validation data