BS6418

antibody from Bioworld Technology, Inc
Targeting: APP AD1
Provider product page for BS6418
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6418 - Provider product page
Provider
Bioworld Technology, Inc
Product name
APP/ÉÇ Amyloid polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human APP/ÉÇ-Amyloid.
Description
Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the ÉÇ-Amyloid and Amyloid A4 proteins, which are present in human platelets. Amyloid deposition is associated with type II diabetes, Down syndrome and a variety of neurological disorders, including Alzheimer£ªs disease. The Amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the Amyloid ÉÇ/A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer£ªs patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane- bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer£ªs disease patients.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
APP protein structure - BS6418 shown in red.