Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- PB9091 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-beta Amyloid/APP Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Rabbit IgG polyclonal antibody for Amyloid beta A4 protein(APP) detection. Tested with WB, IHC-P, IHC-F, ICC/IF, FCM in Human;Mouse;Rat.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Severe tauopathy and axonopathy in the medulla oblongata in Alzheimer's disease implicate the changes in autonomic nervous function.
Maternal Prenatal Inflammation Increases Brain Damage Susceptibility of Lipopolysaccharide in Adult Rat Offspring via COX-2/PGD-2/DPs Pathway Activation.
Effects of alcohol intake on cognitive function and β-amyloid protein in APP/PS1 transgenic mice.
Systematic and experimental investigations of the anti-colorectal cancer mediated by genistein.
α‑lipoic acid can greatly alleviate the toxic effect of AGES on SH‑SY5Y cells.
Combined administration of D-galactose and aluminium induces Alzheimer-like lesions in brain.
Icariin inhibits beta-amyloid peptide segment 25-35 induced expression of beta-secretase in rat hippocampus.
Protection of mouse brain from aluminum-induced damage by caffeic acid.
Protective effects of Ginkgo biloba leaf extract on aluminum-induced brain dysfunction in rats.
Tian Y, Gao G, Dai J
Journal of chemical neuroanatomy 2022 Sep;123:102105
Journal of chemical neuroanatomy 2022 Sep;123:102105
Maternal Prenatal Inflammation Increases Brain Damage Susceptibility of Lipopolysaccharide in Adult Rat Offspring via COX-2/PGD-2/DPs Pathway Activation.
Zhang J, Yao P, Han W, Luo Y, Li Y, Yang Y, Xia H, Chen Z, Chen Q, Wang H, Yang L, Li H, Hu C, Huang H, Peng Z, Tan X, Li M, Yang J
International journal of molecular sciences 2022 May 30;23(11)
International journal of molecular sciences 2022 May 30;23(11)
Effects of alcohol intake on cognitive function and β-amyloid protein in APP/PS1 transgenic mice.
Gong YS, Hou FL, Guo J, Lin L, Zhu FY
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 May;151:112105
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 May;151:112105
Systematic and experimental investigations of the anti-colorectal cancer mediated by genistein.
Zhang L, Zhang J, Gong Y, Lv L
BioFactors (Oxford, England) 2020 Nov;46(6):974-982
BioFactors (Oxford, England) 2020 Nov;46(6):974-982
α‑lipoic acid can greatly alleviate the toxic effect of AGES on SH‑SY5Y cells.
Niu G, Guo J, Tian Y, Zhao K, Li J, Xiao Q
International journal of molecular medicine 2018 May;41(5):2855-2864
International journal of molecular medicine 2018 May;41(5):2855-2864
Combined administration of D-galactose and aluminium induces Alzheimer-like lesions in brain.
Xiao F, Li XG, Zhang XY, Hou JD, Lin LF, Gao Q, Luo HM
Neuroscience bulletin 2011 Jun;27(3):143-55
Neuroscience bulletin 2011 Jun;27(3):143-55
Icariin inhibits beta-amyloid peptide segment 25-35 induced expression of beta-secretase in rat hippocampus.
Nie J, Luo Y, Huang XN, Gong QH, Wu Q, Shi JS
European journal of pharmacology 2010 Jan 25;626(2-3):213-8
European journal of pharmacology 2010 Jan 25;626(2-3):213-8
Protection of mouse brain from aluminum-induced damage by caffeic acid.
Yang JQ, Zhou QX, Liu BZ, He BC
CNS neuroscience & therapeutics 2008 Spring;14(1):10-6
CNS neuroscience & therapeutics 2008 Spring;14(1):10-6
Protective effects of Ginkgo biloba leaf extract on aluminum-induced brain dysfunction in rats.
Gong QH, Wu Q, Huang XN, Sun AS, Shi JS
Life sciences 2005 May 27;77(2):140-8
Life sciences 2005 May 27;77(2):140-8
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- IHC analysis of APP using anti-APP antibody (PB9091).APP was detected in paraffin-embedded section of human glioma tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/ml rabbit anti-APP Antibody (PB9091) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
- Additional image