ABIN362212

antibody from antibodies-online

Targeting: APP AD1

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN362212

Provider

antibodies-online

Product name

anti-Amyloid beta (A4) Precursor Protein (APP) (pThr668) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pThr668 (A-V-T (p) -P-E) derived from Human APP. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pThr668

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.

Iijima K, Ando K, Takeda S, Satoh Y, Seki T, Itohara S, Greengard P, Kirino Y, Nairn AC, Suzuki T
Journal of neurochemistry 2000 Sep;75(3):1085-91

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Synthesis of beta-tubulin, actin, and other proteins in axons of sympathetic neurons in compartmented cultures.

Eng H, Lund K, Campenot RB
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999 Jan 1;19(1):1-9

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Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein.

Suzuki T, Oishi M, Marshak DR, Czernik AJ, Nairn AC, Greengard P
The EMBO journal 1994 Mar 1;13(5):1114-22

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Selective ectodomain phosphorylation and regulated cleavage of beta-amyloid precursor protein.

Hung AY, Selkoe DJ
The EMBO journal 1994 Feb 1;13(3):534-42