67746-1-Ig

antibody from Proteintech Group

Targeting: USP14 TGT

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

67746-1-Ig

Provider

Proteintech Group

Product name

USP14 antibody

Antibody type

Monoclonal

Description

USP14 antibody (Cat. #67746-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IF, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3B12G3

Vial size

20ul, 150ul

References

Submitted references

Andrographolide targets syndecan4 to impair its interaction with syntenin and inhibits the biogenesis of small extracellular vesicles.

Gong Q, Zhao W, Wang T, Pan Y, Cui C, Qu Y, Zhou X
The Journal of biological chemistry 2026 Mar;302(3):111182

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Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response.

Zhao M, Shi J, Wei X, Tian W, Chen Y
Cytokine 2026 Feb;198:157079

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FTO-associated osteoclastogenesis promotes alveolar bone resorption in apical periodontitis male rat via the HK1/USP14/RANK pathway.

Qian Y, Wu J, Yang W, Lyu R, You Q, Li J, He Q, Zhuang Y, Wang W, Wang Y, Zhu Y, Wu Z, Chen D
Nature communications 2025 Feb 11;16(1):1519

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Targeting USP14/UCHL5: A Breakthrough Approach to Overcoming Treatment-Resistant FLT3-ITD-Positive AML.

Nogami A, Amemiya HJ, Fujiwara H, Umezawa Y, Tohda S, Nagao T
International journal of molecular sciences 2024 Sep 26;25(19)

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ALDH2 deficiency augments atherosclerosis through the USP14-cGAS-dependent polarization of proinflammatory macrophages.

Rui H, Yu H, Chi K, Han Z, Zhu W, Zhang J, Guo H, Zou W, Wang F, Xu P, Zou D, Song X, Liu L, Wu X, Wu W, Qin D, Cao Y, Xu F, Xue L, Chen Y
Redox biology 2024 Oct;76:103318

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USP14 promotes the cancer stem-like cell properties of OSCC via promoting SOX2 deubiquitination.

Liu C, Zhou S, Tang W
Oral diseases 2024 Oct;30(7):4255-4265

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USP14 modulates cell pyroptosis and ameliorates doxorubicin-induced cardiotoxicity by deubiquitinating and stabilizing SIRT3.

Zhang Z, Jin B, Zhang Y, Yang M, Wang C, Zhu Y, Li T, Lin J, Yang M, Cheng Y, Xu S, He K, Xu J, Mi Y, Jiang J, Sun Z
Free radical biology & medicine 2024 Nov 20;225:741-757

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GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.

Chen Y, Feng Y, Lin Y, Zhou X, Wang L, Zhou Y, Lin K, Cai L
British journal of cancer 2024 Mar;130(5):755-768