Tissue expression
Cell line expression
Protein structure
USP14
Ubiquitin specific peptidase 14TGT
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
17 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Monoclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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Novus Biologicals | ![]() |
2 references | Monoclonal |
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Abnova Corporation | ![]() |
1 references | Monoclonal |
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