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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 13956-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13956-1-AP, RRID:AB_2161728
- Product name
- PDE8A antibody
- Antibody type
- Polyclonal
- Description
- PDE8A antibody (Cat. #13956-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphodiesterase 8 (PDE8): Distribution and Cellular Expression and Association with Alzheimer's Disease.
Disruption of the pro-oncogenic c-RAF-PDE8A complex represents a differentiated approach to treating KRAS-c-RAF dependent PDAC.
Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.
Mitochondrial sub-cellular localization of cAMP-specific phosphodiesterase 8A in ovarian follicular cells.
Active 3'-5' cyclic nucleotide phosphodiesterases are present in detergent-resistant membranes of mural granulosa cells.
Qiu NZ, Hou HM, Guo TY, Lv YL, Zhou Y, Zhang FF, Zhang F, Wang XD, Chen W, Gao YF, Chen MH, Zhang XH, Zhang HT, Wang H
Neurochemical research 2024 Aug;49(8):1993-2004
Neurochemical research 2024 Aug;49(8):1993-2004
Disruption of the pro-oncogenic c-RAF-PDE8A complex represents a differentiated approach to treating KRAS-c-RAF dependent PDAC.
Cooke SF, Wright TA, Sin YY, Ling J, Kyurkchieva E, Phanthaphol N, Mcskimming T, Herbert K, Rebus S, Biankin AV, Chang DK, Baillie GS, Blair CM
Scientific reports 2024 Apr 18;14(1):8998
Scientific reports 2024 Apr 18;14(1):8998
Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.
Riopel M, Moon JS, Bandyopadhyay GK, You S, Lam K, Liu X, Kisseleva T, Brenner D, Lee YS
Molecular metabolism 2020 Nov;41:101039
Molecular metabolism 2020 Nov;41:101039
Mitochondrial sub-cellular localization of cAMP-specific phosphodiesterase 8A in ovarian follicular cells.
Lounas A, Vernoux N, Germain M, Tremblay ME, Richard FJ
Scientific reports 2019 Aug 28;9(1):12493
Scientific reports 2019 Aug 28;9(1):12493
Active 3'-5' cyclic nucleotide phosphodiesterases are present in detergent-resistant membranes of mural granulosa cells.
Bergeron A, Guillemette C, Sirard MA, Richard FJ
Reproduction, fertility, and development 2017 Apr;29(4):778-790
Reproduction, fertility, and development 2017 Apr;29(4):778-790
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 13956-1-AP(PDE8A antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-PDE8A (IP:13956-1-AP, 5ug; Detection:13956-1-AP 1:1000) with mouse testis tissue lysate 8000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 13956-1-AP(PDE8A antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PDE8A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDE8A. This antibody recognizes human,mouse,rat antigen. The PDE8A antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
