Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx117122 - Provider product page
- Provider
- Abbexa
- Product name
- Antigen Peptide Transporter 2 (TAP2) Antibody
- Antibody type
- Polyclonal
- Description
- TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transportersABC proteins transport various molecules across extra- and intra-cellular membranesABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)This protein is a member of the MDR/TAP subfamilyMembers of the MDR/TAP subfamily are involved in multidrug resistanceThis gene is located 7 kb telomeric to gene family member ABCB2The protein encoded by this gene is involved in antigen presentationThis protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulumMutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac diseaseAlternative splicing of this gene produces two products which differ in peptide selectivity and level of restoRation of surface expression of MHC class I molecules.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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