Tissue expression
Cell line expression

TAP2

gene product
ABCB3, D6S217E, PSF2, RING11 
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Antigen sequence

Conjugate

Epitope

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
238 antibodies from 32 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Acris Antibodies GmbH
2 antibodies
Novus Biologicals
5 antibodies
Biorbyt
13 antibodies
GeneTex
2 antibodies
R&D Systems
1 antibody
LifeSpan BioSciences, Inc.
59 antibodies
Invitrogen Antibodies
5 antibodies
antibodies-online
68 antibodies
Bioworld Technology, Inc
1 antibody
Cusabio Biotech Co., Ltd
7 antibodies
Boster Biological Technology
2 antibodies
Affinity Biosciences
1 antibody
Atlas Antibodies
1 antibody
OriGene
4 antibodies
Abnova Corporation
3 antibodies
Cell Signaling Technology, Inc
1 antibody
NovoPro Bioscience Inc.
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
GenWay
2 antibodies
NSJ Bioreagents
2 antibodies
United States Biological
38 antibodies
Abbexa
4 antibodies
Creative Biolabs
4 antibodies
MyBioSource
2 antibodies
ProSci
1 antibody
Proteintech Group
1 antibody
Creative Diagnostics
2 antibodies
MilliporeSigma / Merck KGaA
1 antibody
RayBiotech, Inc.
1 antibody
Abgent
1 antibody
Leading Biology
1 antibody
CPTAC
1 antibody