Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-L1661 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-Human ZAP70 monoclonal antibody, clone K.058.5
- Antibody type
- Monoclonal
- Description
- This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- K.058.5
- Storage
- -20°C
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