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- Product number
- ABIN238530 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (C-Term) antibody
- Antibody type
- Monoclonal
- Description
- Protein A affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- C-Term
- Isotype
- IgG
- Antibody clone number
- ZAP-03
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Submitted references PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis.
CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization.
Evidence for the involvement of tyrosine kinase ZAP 70 in nuclear retinoid receptor-dependent transactivation in T lymphocytes.
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein.
Hrdinka M, Dráber P, Stepánek O, Ormsby T, Otáhal P, Angelisová P, Brdicka T, Paces J, Horejsí V, Drbal K
The Journal of biological chemistry 2011 Jun 3;286(22):19617-29
The Journal of biological chemistry 2011 Jun 3;286(22):19617-29
CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization.
Schneider H, Smith X, Liu H, Bismuth G, Rudd CE
European journal of immunology 2008 Jan;38(1):40-7
European journal of immunology 2008 Jan;38(1):40-7
Evidence for the involvement of tyrosine kinase ZAP 70 in nuclear retinoid receptor-dependent transactivation in T lymphocytes.
Ishaq M, DeGray G, Natarajan V
The Journal of biological chemistry 2005 Oct 7;280(40):34152-8
The Journal of biological chemistry 2005 Oct 7;280(40):34152-8
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein.
Chan AC, Irving BA, Fraser JD, Weiss A
Proceedings of the National Academy of Sciences of the United States of America 1991 Oct 15;88(20):9166-70
Proceedings of the National Academy of Sciences of the United States of America 1991 Oct 15;88(20):9166-70
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- antibodies-online (provider)
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
