Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN196887 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) antibody
- Antibody type
- Polyclonal
- Description
- Immunoaffinity chromatography using epitope-specific phosphopeptide.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr493
- Vial size
- 50 μL
- Storage
- Store the antibody (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.
Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function.
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.
Salomon AR, Ficarro SB, Brill LM, Brinker A, Phung QT, Ericson C, Sauer K, Brock A, Horn DM, Schultz PG, Peters EC
Proceedings of the National Academy of Sciences of the United States of America 2003 Jan 21;100(2):443-8
Proceedings of the National Academy of Sciences of the United States of America 2003 Jan 21;100(2):443-8
Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function.
Kong G, Dalton M, Bubeck Wardenburg J, Straus D, Kurosaki T, Chan AC
Molecular and cellular biology 1996 Sep;16(9):5026-35
Molecular and cellular biology 1996 Sep;16(9):5026-35
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.
Chan AC, Dalton M, Johnson R, Kong GH, Wang T, Thoma R, Kurosaki T
The EMBO journal 1995 Jun 1;14(11):2499-508
The EMBO journal 1995 Jun 1;14(11):2499-508
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