Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN1881847 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (C-Term), (AA 717-745) antibody
- Antibody type
- Polyclonal
- Antigen
- This STAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 717-745 amino acids from the C-terminal region of human STAT1.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term,AA 717-745
- Antibody clone number
- RB41406
- Vial size
- 400 μL
- Concentration
- 0.47 mg/mL
Submitted references TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein.
Evidence of STAT1 phosphorylation modulated by MAPKs, MEK1 and MSK1.
Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells.
Clarke DL, Clifford RL, Jindarat S, Proud D, Pang L, Belvisi M, Knox AJ
The Journal of biological chemistry 2010 Sep 17;285(38):29101-10
The Journal of biological chemistry 2010 Sep 17;285(38):29101-10
Evidence of STAT1 phosphorylation modulated by MAPKs, MEK1 and MSK1.
Zhang Y, Cho YY, Petersen BL, Zhu F, Dong Z
Carcinogenesis 2004 Jul;25(7):1165-75
Carcinogenesis 2004 Jul;25(7):1165-75
Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells.
Sakamoto S, Qin J, Navarro A, Gamero A, Potla R, Yi T, Zhu W, Baker DP, Feldman G, Larner AC
The Journal of biological chemistry 2004 Jan 30;279(5):3245-53
The Journal of biological chemistry 2004 Jan 30;279(5):3245-53
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- STAT1 Antibody (C-term) (ABIN1881847) western blot analysis in Hela,Jurkat cell line lysates (35 μg/lane). This demonstrates the STAT1 antibody detected the STAT1 protein (arrow).