627302

antibody from BioLegend

Targeting: STAT1 ISGF-3, STAT91

Immunohistochemistry

Antibody data

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Validation data

Product number: 627302 - Provider product page
Provider: BioLegend
Product name: Purified anti-STAT1
Antibody type: Monoclonal
Antigen: STAT1 peptide QLDSKFLEQVHQLYD
Description: STAT1, also known as signal transduction and activator of transcription-1, is a ubiquitously expressed cytoplasmic protein that becomes phosphorylated in response to cytokine signaling (interferon α, interferon γ, EGF, PDGF, and IL-6) by receptor-associated kinases and translocates to the nucleus to act as a transcriptional activator. Two isoforms of STAT1 exist as a result of alternative RNA processing with apparent molecular weights of 88 and 91 kD. STAT1 has been shown to interact with a number of proteins including STAT3, FAK, MCM3, MCM5, TRADD, BRCA1, KIT, IL-27 receptor, IL-2R β and γ, IFNαRβ, STAT2, c-Src, and many others. STAT1 knockout mice are highly sensitive to infection with microbial infections and viruses. The SAT-84 monoclonal antibody recognizes human STAT1 and has been shown to be useful for Western blotting.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: Upon receipt, store undiluted at 4° C.

STAT1 protein structure - 627302 shown in red.