abx105281

antibody from Abbexa

Targeting: C3 ARMD9, C3a, C3b, CPAMD1

No application information provided.

Antibody Data

Product number

abx105281

Provider

Abbexa

Product name

Complement C3 (C3) Antibody (Biotin)

Antibody type

Polyclonal

Description

Complement C3 (C3) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Complement C3. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Reactivity

Human

Host

Rabbit

Conjugate

Biotin

Isotype

IgG

Vial size

100 µg

Storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.