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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Immunohistochemistry [1]
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- Product number
- NB600-576 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-576, RRID:AB_2068461
- Product name
- Rabbit Polyclonal Caspase-8 Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. This reacts with a 55 kDa protein. Caspase 8 has an N-terminal domain with sequence homology to the death effector domain (DED) of FADD. Caspase 8 binds to DED of FADD. Caspase 8 is activated by association with Fas/FADD death-inducing signaling complex to release two active subunits, p18 and p10 into the cytosol, where they activate other caspases amplifying the apoptotic signal.
- Reactivity
- Human, Mouse, Rat, Bovine, Simian
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.5 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references p53-dependent apoptosis in the inhibition of spermatogonial differentiation in juvenile spermatogonial depletion (Utp14bjsd) mice.
Shetty G, Shao SH, Weng CC
Endocrinology 2008 Jun;149(6):2773-81
Endocrinology 2008 Jun;149(6):2773-81
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Caspase 8 Antibody [NB600-576] - Formalin-fixed, paraffin-embedded human stomach stained with Caspase 8. Note cytoplasmic staining of epithelial cells.
