Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB0246 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB0246, RRID:AB_1019082
- Product name
- CASP8 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against full length recombinant CASP8.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death.
Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation.
Marchong MN, Yurkowski C, Ma C, Spencer C, Pajovic S, Gallie BL
PLoS genetics 2010 Apr 22;6(4):e1000923
PLoS genetics 2010 Apr 22;6(4):e1000923
Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation.
Krajewska M, Rosenthal RE, Mikolajczyk J, Stennicke HR, Wiesenthal T, Mai J, Naito M, Salvesen GS, Reed JC, Fiskum G, Krajewski S
Experimental neurology 2004 Oct;189(2):261-79
Experimental neurology 2004 Oct;189(2):261-79
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded sections from a brain tumor tissue array stained for CASP8 expression using CASP8 polyclonal antibody (Cat # PAB0246) at 1 : 2000. A. Anaplastic glioma (Grade III, left) and Gemistocytoma (Grade II, right) cores showing negative and positive staining for CASP8, respectively. B. Higher magnification of the Gemistocytoma tumor (from A) .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)