Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB2358 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2358, RRID:AB_10550216
- Product name
- CASP8 monoclonal antibody, clone FLICE 4-1-20
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against full length recombinant CASP8.
- Isotype
- IgG
- Antibody clone number
- FLICE 4-1-20
- Storage
- Store at 4°C. Do not freeze.
Submitted references Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c.
Oncogene-dependent apoptosis is mediated by caspase-9.
Kirsch DG, Doseff A, Chau BN, Lim DS, de Souza-Pinto NC, Hansford R, Kastan MB, Lazebnik YA, Hardwick JM
The Journal of biological chemistry 1999 Jul 23;274(30):21155-61
The Journal of biological chemistry 1999 Jul 23;274(30):21155-61
Oncogene-dependent apoptosis is mediated by caspase-9.
Fearnhead HO, Rodriguez J, Govek EE, Guo W, Kobayashi R, Hannon G, Lazebnik YA
Proceedings of the National Academy of Sciences of the United States of America 1998 Nov 10;95(23):13664-9
Proceedings of the National Academy of Sciences of the United States of America 1998 Nov 10;95(23):13664-9
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot detection of CASP8 (59 kDa) from 293 cell extract using CASP8 monoclonal antibody, clone FLICE 4-1-20 (Cat #MAB2358) (1 : 500).Lanes 1 and 2 contain inactive and active CASP8, respectively.