Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BMS1102-2 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Caspase 8 Monoclonal Antibody (4-1-20), eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: Caspases are the executioners of apoptosis. These cysteine protease family consists of more than 10 related members characterized by almost absolute specificity for aspartic acid in the P1 position. Caspases are synthesized as inactive proenzymes comprising an N-terminal peptide together with one large and one small subunit. Activation of caspases during apoptosis results in the cleavage of critical cellular substrates so precipitating the dramatic morphological changes of apoptosis. Caspase-8 has been reported to have additional functions unrelated to cell death. It is required for T-cell homeostasis, proliferation, and cell activation. Purity: greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 4/1/2020
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- 4° C
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