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- Product number
- 66093-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66093-1-Ig, RRID:AB_11232214
- Product name
- Caspase 8/p43/p18 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Caspase 8/p43/p18 antibody (Cat. #66093-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2B9H8
- Vial size
- 20ul, 150ul
Submitted references Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Vitamin C Inhibited Pulmonary Metastasis through Activating Nrf2/HO-1 Pathway.
Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies.
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism.
Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer.
A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury.
Revealing the mechanism of fiber promoting sow embryo implantation by altering the abundance of uterine fluid proteins: A proteomic perspective.
Ebastine exerts antitumor activity and induces autophagy by activating AMPK/ULK1 signaling in an IPMK-dependent manner in osteosarcoma.
Activation of STING by SAMHD1 Deficiency Promotes PANoptosis and Enhances Efficacy of PD-L1 Blockade in Diffuse Large B-cell Lymphoma.
Extracellular vesicles produced by avian pathogenic Escherichia coli (APEC) activate macrophage proinflammatory response and neutrophil extracellular trap (NET) formation through TLR4 signaling.
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
Quizartinib inhibits necroptosis by targeting receptor-interacting serine/threonine protein kinase 1.
Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.
Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease.
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis.
METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer.
Blue light photobiomodulation induced apoptosis by increasing ROS level and regulating SOCS3 and PTEN/PI3K/AKT pathway in osteosarcoma cells.
The TRIM21-FOXD1-BCL-2 axis underlies hyperglycaemic cell death and diabetic tissue damage.
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis.
Targeting the LSD1-G9a-ER Stress Pathway as a Novel Therapeutic Strategy for Esophageal Squamous Cell Carcinoma.
Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2.
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Caspase-8 activation in neutrophils facilitates autoimmune kidney vasculitis through regulating CD4(+) effector memory T cells.
LOXL2 small molecule inhibitor restrains malignant transformation of cervical cancer cells by repressing LOXL2-induced epithelial-mesenchymal transition (EMT).
A natural halogenated fluoride adenosine analog 5'-fluorodeoxy adenosine induced anticolon cancer activity in vivo and in vitro.
Pyroptosis: a novel signature to predict prognosis and immunotherapy response in gliomas.
Fusion of an EGFR-antagonistic affibody enhances the anti-tumor effect of TRAIL to EGFR positive tumors.
Bclaf1 regulates c-FLIP expression and protects cells from TNF-induced apoptosis and tissue injury.
PHLPP1 deficiency ameliorates cardiomyocyte death and cardiac dysfunction through inhibiting Mcl-1 degradation.
Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis.
TRAIL-modified, doxorubicin-embedded periodic mesoporous organosilica nanoparticles for targeted drug delivery and efficient antitumor immunotherapy.
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway.
Sonodynamic Effects of a Novel Ether-Group Modified Porphyrin Derivative Combined With Pulsed Low-Intensity Ultrasound on PC-9 Cells.
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy.
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Short-term high-fat diet favors the appearances of apoptosis and gliosis by activation of ERK1/2/p38MAPK pathways in brain.
The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.
Nogo-A-Δ20/EphA4 interaction antagonizes apoptosis of neural stem cells by integrating p38 and JNK MAPK signaling.
Integration of exonuclease III-powered three-dimensional DNA walker with single-molecule detection for multiple initiator caspases assay.
Autophagy Induced by Simian Retrovirus Infection Controls Viral Replication and Apoptosis of Jurkat T Lymphocytes.
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice.
Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover.
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-α: Knockdown p53 negatively modulates antiviral response.
Ebselen protects rat hearts against myocardial ischemia-reperfusion injury.
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Restoration of p53 acetylation by HDAC inhibition permits the necrosis/apoptosis switch of pancreatic ainar cell during experimental pancreatitis in mice.
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.
Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary.
Critical contribution of RIPK1 mediated mitochondrial dysfunction and oxidative stress to compression-induced rat nucleus pulposus cells necroptosis and apoptosis.
Quinacrine upregulates p21/p27 independent of p53 through autophagy-mediated downregulation of p62-Skp2 axis in ovarian cancer.
Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways.
Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.
TRAIL Deletion Prevents Liver, but Not Adipose Tissue, Inflammation during Murine Diet-Induced Obesity.
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo.
DR5-Cbl-b/c-Cbl-TRAF2 complex inhibits TRAIL-induced apoptosis by promoting TRAF2-mediated polyubiquitination of caspase-8 in gastric cancer cells.
RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system.
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis.
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.
Wang Y, Chen SJ, Ma T, Long Q, Chen L, Xu KX, Cao Y
International immunopharmacology 2024 Sep 10;138:112517
International immunopharmacology 2024 Sep 10;138:112517
Vitamin C Inhibited Pulmonary Metastasis through Activating Nrf2/HO-1 Pathway.
Man S, Bi J, Liu F, Xie W, Ma L
Molecular nutrition & food research 2024 Mar;68(6):e2300706
Molecular nutrition & food research 2024 Mar;68(6):e2300706
Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies.
Tang L, Zhang H, Zhou F, Wei Q, Du M, Wu J, Li C, Luo W, Zhou J, Wang X, Chen Z, Zhang Y, Huang Z, Wu Z, Wen Y, Jiang H, Liao D, Kou H, Xiong W, Mei H, Hu Y
Cancer communications (London, England) 2024 Mar;44(3):408-432
Cancer communications (London, England) 2024 Mar;44(3):408-432
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
Ma H, Suleman M, Zhang F, Cao T, Wen S, Sun D, Chen L, Jiang B, Wang Y, Lin F, Wang J, Li B, Li Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2301476
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2301476
GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism.
Wang R, Min Q, Guo Y, Zhou Y, Zhang X, Wang D, Gao Y, Wei L
iScience 2024 Mar 15;27(3):109246
iScience 2024 Mar 15;27(3):109246
Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer.
Liu S, Tao Y, Wu S, Lin J, Fu S, Lu J, Zhang J, Fu B, Zhang E, Xu J, Wang J, Li L, Zhang L, Wang Z
Chinese medicine 2024 Jan 9;19(1):7
Chinese medicine 2024 Jan 9;19(1):7
A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury.
Xie L, Wu H, He Q, Shi W, Zhang J, Xiao X, Yu T
Cell communication and signaling : CCS 2024 Jan 12;22(1):33
Cell communication and signaling : CCS 2024 Jan 12;22(1):33
Revealing the mechanism of fiber promoting sow embryo implantation by altering the abundance of uterine fluid proteins: A proteomic perspective.
Chang J, Pan X, Gao J, Zhuo Y, Jiang X, Che L, Lin Y, Fang Z, Feng B, Li J, Hua L, Zhao X, Zhang R, Wu D, Xu S
Journal of proteomics 2024 Apr 15;297:105123
Journal of proteomics 2024 Apr 15;297:105123
Ebastine exerts antitumor activity and induces autophagy by activating AMPK/ULK1 signaling in an IPMK-dependent manner in osteosarcoma.
Pan Z, Li SJ, Guo H, Li ZH, Fei X, Chang SM, Yang QC, Cheng DD
International journal of biological sciences 2023;19(2):537-551
International journal of biological sciences 2023;19(2):537-551
Activation of STING by SAMHD1 Deficiency Promotes PANoptosis and Enhances Efficacy of PD-L1 Blockade in Diffuse Large B-cell Lymphoma.
Cai Y, Chen X, Lu T, Fang X, Ding M, Yu Z, Hu S, Liu J, Zhou X, Wang X
International journal of biological sciences 2023;19(14):4627-4643
International journal of biological sciences 2023;19(14):4627-4643
Extracellular vesicles produced by avian pathogenic Escherichia coli (APEC) activate macrophage proinflammatory response and neutrophil extracellular trap (NET) formation through TLR4 signaling.
Wang Z, Zhu D, Zhang Y, Xia F, Zhu J, Dai J, Zhuge X
Microbial cell factories 2023 Sep 9;22(1):177
Microbial cell factories 2023 Sep 9;22(1):177
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
Li Y, Ge Y, Zhao M, Ding F, Wang X, Shi Z, Ge X, Wang X, Qian X
Journal of biomedical research 2023 Sep 28;37(5):326-339
Journal of biomedical research 2023 Sep 28;37(5):326-339
Quizartinib inhibits necroptosis by targeting receptor-interacting serine/threonine protein kinase 1.
Li M, Wei J, Zhu G, Fu S, He X, Hu X, Yu Y, Mou Y, Wang J, You X, Xiao X, Gu T, Ye Z, Zha Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23178
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23178
Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.
Zhang H, Xia P, Yang Z, Liu J, Zhu Y, Huang Z, Zhang Z, Yuan Y
Clinical and translational medicine 2023 Oct;13(10):e1443
Clinical and translational medicine 2023 Oct;13(10):e1443
Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.
Ge Z, Xu M, Ge Y, Huang G, Chen D, Ye X, Xiao Y, Zhu H, Yin R, Shen H, Ma G, Qi L, Wei G, Li D, Wei S, Zhu M, Ma H, Shi Z, Wang X, Ge X, Qian X
Cell reports 2023 Nov 28;42(11):113417
Cell reports 2023 Nov 28;42(11):113417
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Liang JP, He YM, Cui YL, Sun YN, He GS, Zhu ZG, Mao XL
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474
SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease.
Wen Z, Xia Y, Zhang Y, He Y, Niu C, Wu R, Zhang C, Jia C, Rong X, Chu M
Italian journal of pediatrics 2023 Jan 4;49(1):2
Italian journal of pediatrics 2023 Jan 4;49(1):2
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis.
Wu J, Lin S, Chen W, Lian G, Wu W, Chen A, Sagor MIH, Luo L, Wang H, Xie L
Cell death discovery 2023 Feb 24;9(1):76
Cell death discovery 2023 Feb 24;9(1):76
METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer.
Ouyang D, Hong T, Fu M, Li Y, Zeng L, Chen Q, He H, Wen Y, Cheng Y, Zhou M, Zou Q, Yi W
Breast cancer research : BCR 2023 Feb 10;25(1):19
Breast cancer research : BCR 2023 Feb 10;25(1):19
Blue light photobiomodulation induced apoptosis by increasing ROS level and regulating SOCS3 and PTEN/PI3K/AKT pathway in osteosarcoma cells.
Yang J, Jiang H, Fu Q, Qin H, Li Y, Liu M
Journal of photochemistry and photobiology. B, Biology 2023 Dec;249:112814
Journal of photochemistry and photobiology. B, Biology 2023 Dec;249:112814
The TRIM21-FOXD1-BCL-2 axis underlies hyperglycaemic cell death and diabetic tissue damage.
Cheng W, Cai C, Xu Y, Xiao X, Shi T, Liao Y, Wang X, Chen S, Zhou M, Liao Z
Cell death & disease 2023 Dec 13;14(12):825
Cell death & disease 2023 Dec 13;14(12):825
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis.
Xu Z, Zhang M, Wang W, Zhou S, Yu M, Qiu X, Jiang S, Wang X, Tang C, Li S, Wang CH, Zhu R, Peng WX, Zhao L, Fu X, Patzak A, Persson PB, Zhao L, Mao J, Shu Q, Lai EY, Zhang G
Toxicology and applied pharmacology 2023 Aug 15;473:116595
Toxicology and applied pharmacology 2023 Aug 15;473:116595
Targeting the LSD1-G9a-ER Stress Pathway as a Novel Therapeutic Strategy for Esophageal Squamous Cell Carcinoma.
Wang H, Song Z, Xie E, Chen J, Tang B, Wang F, Min J
Research (Washington, D.C.) 2022;2022:9814652
Research (Washington, D.C.) 2022;2022:9814652
Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2.
Shen B, Zhang R, Yang G, Peng Y, Nie Q, Yu H, Dong W, Chen B, Song C, Tian Y, Qin L, Shu J, Hong S, Li L
Frontiers in pharmacology 2022;13:972828
Frontiers in pharmacology 2022;13:972828
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Qu XQ, Chen QF, Shi QQ, Luo QQ, Zheng SY, Li YH, Bai LY, Gan S, Zhou XY
Frontiers in immunology 2022;13:901566
Frontiers in immunology 2022;13:901566
Caspase-8 activation in neutrophils facilitates autoimmune kidney vasculitis through regulating CD4(+) effector memory T cells.
Hu J, Huang Z, Yu M, Zhang P, Xia Z, Gao C
Frontiers in immunology 2022;13:1038134
Frontiers in immunology 2022;13:1038134
LOXL2 small molecule inhibitor restrains malignant transformation of cervical cancer cells by repressing LOXL2-induced epithelial-mesenchymal transition (EMT).
Peng T, Lin S, Meng Y, Gao P, Wu P, Zhi W, Ding W, Cao C, Wu P
Cell cycle (Georgetown, Tex.) 2022 Sep;21(17):1827-1841
Cell cycle (Georgetown, Tex.) 2022 Sep;21(17):1827-1841
A natural halogenated fluoride adenosine analog 5'-fluorodeoxy adenosine induced anticolon cancer activity in vivo and in vitro.
Ma L, Liu T, Lu Y, Dong Y, Zhao X, Man S
Environmental toxicology 2022 Oct;37(10):2493-2502
Environmental toxicology 2022 Oct;37(10):2493-2502
Pyroptosis: a novel signature to predict prognosis and immunotherapy response in gliomas.
He G, Chen Z, Zhuo S, Tang J, Hao W, Yang K, Yang C
Human cell 2022 Nov;35(6):1976-1992
Human cell 2022 Nov;35(6):1976-1992
Fusion of an EGFR-antagonistic affibody enhances the anti-tumor effect of TRAIL to EGFR positive tumors.
Jia D, Wang F, Lu Y, Hu P, Wang R, Li G, Liu R, Li J, Liu H, Fan Q, Yuan F
International journal of pharmaceutics 2022 May 25;620:121746
International journal of pharmaceutics 2022 May 25;620:121746
Bclaf1 regulates c-FLIP expression and protects cells from TNF-induced apoptosis and tissue injury.
Zhang R, Xue T, Shao A, Lang Y, Qin C, Zhao M, Kuang Y, Yu Z, Geng Y, Zhao C, Tang J
EMBO reports 2022 Jan 5;23(1):e52702
EMBO reports 2022 Jan 5;23(1):e52702
PHLPP1 deficiency ameliorates cardiomyocyte death and cardiac dysfunction through inhibiting Mcl-1 degradation.
Tan Y, Li T, Hu M, Wang B, Zhou Q, Jiang Y, Zhang S, Duan X, Yang J, Liu X, Zhan Z
Cellular signalling 2022 Apr;92:110281
Cellular signalling 2022 Apr;92:110281
Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis.
Yu H, Li M, Wen X, Yang J, Liang X, Li X, Bao X, Shu J, Ren X, Chen W, Li Z, Li Y
Arthritis research & therapy 2022 Apr 29;24(1):93
Arthritis research & therapy 2022 Apr 29;24(1):93
TRAIL-modified, doxorubicin-embedded periodic mesoporous organosilica nanoparticles for targeted drug delivery and efficient antitumor immunotherapy.
Feng X, Li F, Zhang L, Liu W, Wang X, Zhu R, Qiao ZA, Yu B, Yu X
Acta biomaterialia 2022 Apr 15;143:392-405
Acta biomaterialia 2022 Apr 15;143:392-405
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Ma N, Yang X, Qi C, Yu Q, Zhu C, Ren H
Oxidative medicine and cellular longevity 2021;2021:8847844
Oxidative medicine and cellular longevity 2021;2021:8847844
MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway.
Ke J, Zhao F, Luo Y, Deng F, Wu X
International journal of biological sciences 2021;17(8):2099-2111
International journal of biological sciences 2021;17(8):2099-2111
Sonodynamic Effects of a Novel Ether-Group Modified Porphyrin Derivative Combined With Pulsed Low-Intensity Ultrasound on PC-9 Cells.
Jin Y, Zhou Q, Geng J, Meng Q, Wei Z, Ding M, Zhou J, Zeng Y, Cao W, Liu F, Yu Y
Frontiers in pharmacology 2021;12:792360
Frontiers in pharmacology 2021;12:792360
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy.
Liu H, Wei J, Sang N, Zhong X, Zhou X, Yang X, Zhang J, Zuo Z, Zhou Y, Yang S, Du J, Zhao Y
Medical oncology (Northwood, London, England) 2021 Sep 7;38(10):124
Medical oncology (Northwood, London, England) 2021 Sep 7;38(10):124
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Zeng L, Zou Q, Huang P, Xiong L, Cheng Y, Chen Q, Li Y, He H, Yi W, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Short-term high-fat diet favors the appearances of apoptosis and gliosis by activation of ERK1/2/p38MAPK pathways in brain.
Xu CJ, Li MQ, Li-Zhao, Chen WG, Wang JL
Aging 2021 Oct 7;13(19):23133-23148
Aging 2021 Oct 7;13(19):23133-23148
The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.
Zhang S, Zhao X, Hao J, Zhu Y, Wang Y, Wang L, Guo S, Yi H, Liu Y, Liu J
Journal of hazardous materials 2021 May 15;410:124607
Journal of hazardous materials 2021 May 15;410:124607
Nogo-A-Δ20/EphA4 interaction antagonizes apoptosis of neural stem cells by integrating p38 and JNK MAPK signaling.
Wang JL, Chen WG, Zhang JJ, Xu CJ
Journal of molecular histology 2021 Jun;52(3):521-537
Journal of molecular histology 2021 Jun;52(3):521-537
Integration of exonuclease III-powered three-dimensional DNA walker with single-molecule detection for multiple initiator caspases assay.
Liu M, Xu R, Liu W, Qiu JG, Wang Y, Ma F, Zhang CY
Chemical science 2021 Dec 8;12(47):15645-15654
Chemical science 2021 Dec 8;12(47):15645-15654
Autophagy Induced by Simian Retrovirus Infection Controls Viral Replication and Apoptosis of Jurkat T Lymphocytes.
Zhu J, Yang L, Zhang Q, Meng J, Lu ZL, Rong R
Viruses 2020 Mar 31;12(4)
Viruses 2020 Mar 31;12(4)
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Liu C, Wang F, Wang B, Wu T, Wang Y, Huo W, Zhang S, Su Y, Liu J, Liu Y, Yu J
Oncology letters 2020 Dec;20(6):358
Oncology letters 2020 Dec;20(6):358
Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice.
Yaron JR, Chen H, Ambadapadi S, Zhang L, Tafoya AM, Munk BH, Wakefield DN, Fuentes J, Marques BJ, Harripersaud K, Bartee MY, Davids JA, Zheng D, Rand K, Dixon L, Moyer RW, Clapp WL, Lucas AR
Journal of inflammation (London, England) 2019;16:12
Journal of inflammation (London, England) 2019;16:12
Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover.
Li D, Chen J, Ai Y, Gu X, Li L, Che D, Jiang Z, Li L, Chen S, Huang H, Wang J, Cai T, Cao Y, Qi X, Wang X
Molecular cell 2019 Sep 19;75(6):1103-1116.e9
Molecular cell 2019 Sep 19;75(6):1103-1116.e9
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Xia Y, Chen S, Zhao Y, Chen S, Huang R, Zhu G, Yin Y, Ren W, Deng J
Food & function 2019 Nov 1;10(11):7509-7522
Food & function 2019 Nov 1;10(11):7509-7522
Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-α: Knockdown p53 negatively modulates antiviral response.
Li S, Wang Y, Zhao H, Shao Y, Liu J, Xing M
Developmental and comparative immunology 2019 Jan;90:29-40
Developmental and comparative immunology 2019 Jan;90:29-40
Ebselen protects rat hearts against myocardial ischemia-reperfusion injury.
Cheng B, Zhong JP, Wu FX, Li GL, Ruan QX, Luo G, Jiang H
Experimental and therapeutic medicine 2019 Feb;17(2):1412-1419
Experimental and therapeutic medicine 2019 Feb;17(2):1412-1419
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Zeng N, Zhang Z, Jiang H, Li R, Chang C, Wang F, Xu D, Fan Q, Wang T, Xiao Y, Chen W, Shan Z, Huang Z, Wang Q
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Toxicology in vitro : an international journal published in association with BIBRA 2019 Dec;61:104650
Restoration of p53 acetylation by HDAC inhibition permits the necrosis/apoptosis switch of pancreatic ainar cell during experimental pancreatitis in mice.
Hu Y, Dai J, Zong G, Xiao J, Guo X, Dai Y, Lu Z, Wan R
Journal of cellular physiology 2019 Dec;234(12):21988-21998
Journal of cellular physiology 2019 Dec;234(12):21988-21998
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
Li SS, Jiang WL, Xiao WQ, Li K, Zhang YF, Guo XY, Dai YQ, Zhao QY, Jiang MJ, Lu ZJ, Wan R
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
Li X, Qiu Z, Jin Q, Chen G, Guo M
Frontiers in pharmacology 2018;9:629
Frontiers in pharmacology 2018;9:629
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways.
Zhang GY, Lu D, Duan SF, Gao YR, Liu SY, Hong Y, Dong PZ, Chen YG, Li T, Wang DY, Cheng XS, He F, Wei JS, Li GY, Zhang QY, Wu DD, Ji XY
Oxidative medicine and cellular longevity 2018;2018:9647809
Oxidative medicine and cellular longevity 2018;2018:9647809
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken.
Shao YZ, Zhao HJ, Wang Y, Liu JJ, Li JL, Luo LY, Xing MW
Poultry science 2018 Sep 1;97(9):3248-3257
Poultry science 2018 Sep 1;97(9):3248-3257
Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota.
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Journal of pineal research 2018 Mar;64(2)
Journal of pineal research 2018 Mar;64(2)
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary.
Cao J, Liu XM, Huang LL, Wang L, Jiao XF, Huo LJ
International journal of molecular medicine 2018 Jun;41(6):3115-3126
International journal of molecular medicine 2018 Jun;41(6):3115-3126
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Apoptosis : an international journal on programmed cell death 2018 Jun;23(5-6):299-313
Apoptosis : an international journal on programmed cell death 2018 Jun;23(5-6):299-313
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Scientific reports 2018 Feb 6;8(1):2487
Scientific reports 2018 Feb 6;8(1):2487
Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.
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Cancer medicine 2018 Apr;7(4):1546-1559
Cancer medicine 2018 Apr;7(4):1546-1559
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Oxidative medicine and cellular longevity 2017;2017:6175841
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Hepatology communications 2017 Sep;1(7):648-662
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International immunopharmacology 2017 May;46:124-132
International immunopharmacology 2017 May;46:124-132
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Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
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The international journal of biochemistry & cell biology 2017 Dec;93:1-11
The international journal of biochemistry & cell biology 2017 Dec;93:1-11
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Molecular oncology 2017 Dec;11(12):1733-1751
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Li D, Meng L, Xu T, Su Y, Liu X, Zhang Z, Wang X
eLife 2017 Aug 15;6
eLife 2017 Aug 15;6
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Cellular microbiology 2017 Apr;19(4)
Cellular microbiology 2017 Apr;19(4)
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PloS one 2016;11(4):e0152570
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Radiation research 2016 Jan;185(1):77-86
Radiation research 2016 Jan;185(1):77-86
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International journal of oncology 2015 Aug;47(2):701-9
International journal of oncology 2015 Aug;47(2):701-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Caspase 8 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human Caspase 8. This antibody recognizes human antigen. The Caspase 8 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
