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- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN967337 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) antibody
- Antibody type
- Monoclonal
- Antigen
- Human caspase-8 recombinant protein
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 43834
- Vial size
- 150 μg
- Concentration
- 0.5 mg/ml
- Storage
- 4°C
Submitted references Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation.
Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase.
Oncogene-dependent apoptosis is mediated by caspase-9.
CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
Boesen-de Cock JG, Tepper AD, de Vries E, van Blitterswijk WJ, Borst J
The Journal of biological chemistry 1999 May 14;274(20):14255-61
The Journal of biological chemistry 1999 May 14;274(20):14255-61
Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase.
Thome M, Martinon F, Hofmann K, Rubio V, Steiner V, Schneider P, Mattmann C, Tschopp J
The Journal of biological chemistry 1999 Apr 9;274(15):9962-8
The Journal of biological chemistry 1999 Apr 9;274(15):9962-8
Oncogene-dependent apoptosis is mediated by caspase-9.
Fearnhead HO, Rodriguez J, Govek EE, Guo W, Kobayashi R, Hannon G, Lazebnik YA
Proceedings of the National Academy of Sciences of the United States of America 1998 Nov 10;95(23):13664-9
Proceedings of the National Academy of Sciences of the United States of America 1998 Nov 10;95(23):13664-9
CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.
Cock JG, Tepper AD, de Vries E, van Blitterswijk WJ, Borst J
The Journal of biological chemistry 1998 Mar 27;273(13):7560-5
The Journal of biological chemistry 1998 Mar 27;273(13):7560-5
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.
Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, Neipel F, Mattmann C, Burns K, Bodmer JL, Schröter M, Scaffidi C, Krammer PH, Peter ME, Tschopp J
Nature 1997 Apr 3;386(6624):517-21
Nature 1997 Apr 3;386(6624):517-21
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME, Dixit VM
Cell 1996 Jun 14;85(6):817-27
Cell 1996 Jun 14;85(6):817-27
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