CABT-B022

antibody from Creative Diagnostics

Targeting: BTK AGMX1, ATK, IMD1, PSCTK1, XLA

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

CABT-B022

Provider

Creative Diagnostics

Product name

Anti-BTK (aa1-175) monoclonal antibody, clone 20E22

Antibody type

Monoclonal

Description

BTK (Brutons tyrosine kinase), also known as BPK or ATK, is a member of the TEC family of non-receptor protein tyrosine kinase which includes Bmx, Itk and TEC. BTK plays a crucial role in B cell activation and development. Similar to Etk-TNFR2 interaction, Btk interacts with Fas, a member of the TNFR family involved in apoptosis in a ligand-independent manner. Mutations in the Btk gene have been linked to severe developmental blocks in human B-cell ontogeny leading to X-linked agammaglobulinemia (XLA).

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2.00E+23

Vial size

100_g

Concentration

1mg/mL

Storage

Store at -20°C