Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B022 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-BTK (aa1-175) monoclonal antibody, clone 20E22
- Antibody type
- Monoclonal
- Description
- BTK (Brutons tyrosine kinase), also known as BPK or ATK, is a member of the TEC family of non-receptor protein tyrosine kinase which includes Bmx, Itk and TEC. BTK plays a crucial role in B cell activation and development. Similar to Etk-TNFR2 interaction, Btk interacts with Fas, a member of the TNFR family involved in apoptosis in a ligand-independent manner. Mutations in the Btk gene have been linked to severe developmental blocks in human B-cell ontogeny leading to X-linked agammaglobulinemia (XLA).
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2.00E+23
- Vial size
- 100_g
- Concentration
- 1mg/mL
- Storage
- Store at -20°C
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