Tissue expression
Cell line expression
Protein structure
BTK
Bruton tyrosine kinaseAGMX1, ATK, IMD1, PSCTK1, XLA
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Top validated antibodies |
|||||
| LSBio | Polyclonal |
|
|||
| Invitrogen Antibodies | 1 references | Monoclonal |
|
||
| OriGene | 1 references | Monoclonal |
|
||
| Novus Biologicals | 3 references | Polyclonal |
|
||
| antibodies-online | 3 references | Monoclonal |
|
||