orb106905

antibody from Biorbyt

Targeting: LIG4

Western blot (Data presented on provider website)

Antibody Data

Product number

orb106905

Provider

Biorbyt

Product name

LIG4 antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Rabbit polyclonal to LIG4. Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antibody clone number

RB40331

Vial size

80 ul

Storage

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles