GTX30294

antibody from GeneTex

Targeting: MRE11 ATLD, MRE11A

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Chromatin Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

GTX30294

Provider

GeneTex

Proper citation

Product name

Mre11 antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat, Chicken/Avian, Hamster

Host

Rabbit

References

Submitted references

Telomere maintenance and cell cycle regulation in spontaneously immortalized T-cell lines from Nijmegen breakage syndrome patients.

Siwicki JK, Degerman S, Chrzanowska KH, Roos G
Experimental cell research 2003 Jul 1;287(1):178-89

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Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1.

Her C, Vo AT, Wu X
DNA repair 2002 Sep 4;1(9):719-29

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Polymerase eta and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation.

Cleaver JE, Bartholomew J, Char D, Crowley E, Feeney L, Limoli CL
DNA repair 2002 Jan 22;1(1):41-57

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DNA replication arrest in XP variant cells after UV exposure is diverted into an Mre11-dependent recombination pathway by the kinase inhibitor wortmannin.

Limoli CL, Laposa R, Cleaver JE
Mutation research 2002 Dec 29;510(1-2):121-9

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Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest.

Franchitto A, Pichierri P
The Journal of cell biology 2002 Apr 1;157(1):19-30

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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.

Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J
Genes & development 2000 Apr 15;14(8):927-39

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Western Blot: Mre11 Antibody [GTX30294] - Analysis of Mre11 on 50 μg of HeLa and MEF lysates, using GTX30294.

Immunocytochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Indirect immunofluorescence to detect localisation of Mre11 in normal lymphoblastoid cells. (Panel D - negative control). Image supplied by Dr Domenico Delia, Istituto Nazionale Tumori, Italy.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunocytochemistry/Immunofluorescence: Mre11 Antibody [GTX30294] - Detection of MRE11 (Green) in Hela cells using GTX30294 at a 1:200 dilution. Nuclei (Blue) are counterstained using Hoechst 33258.

Immunohistochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunohistochemistry: Mre11 Antibody [GTX30294] - MRE11 staining in the human epidermis detected with GTX30294.