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antibody from GeneTex
Targeting: MRE11
ATLD, MRE11A
Western blot Immunocytochemistry
Immunoprecipitation Immunohistochemistry Flow cytometry Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [2]
- Immunohistochemistry [1]
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- Product number
- GTX30294 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX30294, RRID:AB_374407
- Product name
- Mre11 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Hamster
- Host
- Rabbit
Submitted references Telomere maintenance and cell cycle regulation in spontaneously immortalized T-cell lines from Nijmegen breakage syndrome patients.
Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1.
Polymerase eta and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation.
DNA replication arrest in XP variant cells after UV exposure is diverted into an Mre11-dependent recombination pathway by the kinase inhibitor wortmannin.
Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest.
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.
Siwicki JK, Degerman S, Chrzanowska KH, Roos G
Experimental cell research 2003 Jul 1;287(1):178-89
Experimental cell research 2003 Jul 1;287(1):178-89
Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1.
Her C, Vo AT, Wu X
DNA repair 2002 Sep 4;1(9):719-29
DNA repair 2002 Sep 4;1(9):719-29
Polymerase eta and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation.
Cleaver JE, Bartholomew J, Char D, Crowley E, Feeney L, Limoli CL
DNA repair 2002 Jan 22;1(1):41-57
DNA repair 2002 Jan 22;1(1):41-57
DNA replication arrest in XP variant cells after UV exposure is diverted into an Mre11-dependent recombination pathway by the kinase inhibitor wortmannin.
Limoli CL, Laposa R, Cleaver JE
Mutation research 2002 Dec 29;510(1-2):121-9
Mutation research 2002 Dec 29;510(1-2):121-9
Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest.
Franchitto A, Pichierri P
The Journal of cell biology 2002 Apr 1;157(1):19-30
The Journal of cell biology 2002 Apr 1;157(1):19-30
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.
Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J
Genes & development 2000 Apr 15;14(8):927-39
Genes & development 2000 Apr 15;14(8):927-39
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western Blot: Mre11 Antibody [GTX30294] - Analysis of Mre11 on 50 μg of HeLa and MEF lysates, using GTX30294.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Indirect immunofluorescence to detect localisation of Mre11 in normal lymphoblastoid cells. (Panel D - negative control). Image supplied by Dr Domenico Delia, Istituto Nazionale Tumori, Italy.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: Mre11 Antibody [GTX30294] - Detection of MRE11 (Green) in Hela cells using GTX30294 at a 1:200 dilution. Nuclei (Blue) are counterstained using Hoechst 33258.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemistry: Mre11 Antibody [GTX30294] - MRE11 staining in the human epidermis detected with GTX30294.
