Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB12381 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12381, RRID:AB_10552698
- Product name
- MRE11A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against MRE11A.
- Storage
- Store at 4°C for short term storage. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.
Temporal regulation of the Mre11-Rad50-Nbs1 complex during adenovirus infection.
ATM activation and signaling under hypoxic conditions.
Ataxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in Simian virus 40-infected primate cells.
Cellular proteins PML and Daxx mediate an innate antiviral defense antagonized by the adenovirus E4 ORF3 protein.
DNA replication licensing in somatic and germ cells.
Diner BA, Li T, Greco TM, Crow MS, Fuesler JA, Wang J, Cristea IM
Molecular systems biology 2015 Feb 9;11(1):787
Molecular systems biology 2015 Feb 9;11(1):787
Temporal regulation of the Mre11-Rad50-Nbs1 complex during adenovirus infection.
Karen KA, Hoey PJ, Young CS, Hearing P
Journal of virology 2009 May;83(9):4565-73
Journal of virology 2009 May;83(9):4565-73
ATM activation and signaling under hypoxic conditions.
Bencokova Z, Kaufmann MR, Pires IM, Lecane PS, Giaccia AJ, Hammond EM
Molecular and cellular biology 2009 Jan;29(2):526-37
Molecular and cellular biology 2009 Jan;29(2):526-37
Ataxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in Simian virus 40-infected primate cells.
Zhao X, Madden-Fuentes RJ, Lou BX, Pipas JM, Gerhardt J, Rigell CJ, Fanning E
Journal of virology 2008 Jun;82(11):5316-28
Journal of virology 2008 Jun;82(11):5316-28
Cellular proteins PML and Daxx mediate an innate antiviral defense antagonized by the adenovirus E4 ORF3 protein.
Ullman AJ, Hearing P
Journal of virology 2008 Aug;82(15):7325-35
Journal of virology 2008 Aug;82(15):7325-35
DNA replication licensing in somatic and germ cells.
Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI, Prevost AT, Blow JJ, Stoeber K, Williams GH
Journal of cell science 2004 Nov 15;117(Pt 24):5875-86
Journal of cell science 2004 Nov 15;117(Pt 24):5875-86
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of MRE11A on 50 ug of HeLa and MEF lysates, using MRE11A polyclonal antibody (Cat # PAB12381).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Staining of MRE11A in the human epidermis using MRE11A polyclonal antibody (Cat # PAB12381).
- Validation comment
- Immunohistochemistry