C7

gene product
This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
268 antibodies from 32 providers.

Antibody properties

General

Applications

or Cancel
Antibody
antibodies-online
55 antibodies
Aviva Systems Biology
2 antibodies
GeneTex
5 antibodies
NSJ Bioreagents
3 antibodies
OriGene
4 antibodies
Acris Antibodies GmbH
3 antibodies
Invitrogen Antibodies
3 antibodies
LifeSpan BioSciences, Inc.
92 antibodies
Affinity Biosciences
1 antibody
Novus Biologicals
6 antibodies
Biorbyt
12 antibodies
Atlas Antibodies
1 antibody
ProSci
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
St John's Laboratory
3 antibodies
RabMAbs
2 antibodies
Abbexa
1 antibody
Antibodies.com
1 antibody
Bioworld Technology, Inc
1 antibody
Boster Biological Technology
1 antibody
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
Abnova Corporation
5 antibodies
Creative Biolabs
7 antibodies
MyBioSource
7 antibodies
Abgent
1 antibody
United States Biological
37 antibodies
Creative Diagnostics
4 antibodies
GenWay
2 antibodies
Sigma-Aldrich
2 antibodies
Everest Biotech
1 antibody
Sino Biological Inc.
1 antibody