NB100-63270

antibody from Novus Biologicals

Targeting: C7

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

NB100-63270

Provider

Novus Biologicals

Proper citation

Novus Cat#NB100-63270, RRID:AB_960758

Product name

Mouse Monoclonal Complement C7 Antibody

Antibody type

Monoclonal

Description

Protein A purified. NB100-63270 recognizes complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Note that this antibody does not recognise membrane bound complement membrane attack complex. This antibody inhibits lysis of sensitised sheep erythrocytes.

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

0.05 mg

Concentration

1.0 mg/ml

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.