Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10825-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10825-1-AP, RRID:AB_2192022
- Product name
- SNAP23 antibody
- Antibody type
- Polyclonal
- Description
- SNAP23 antibody (Cat. #10825-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Zixue Powder attenuates septic thrombosis via reducing neutrophil extracellular trap through blocking platelet STING activation.
Identification of the SNARE complex that mediates the fusion of multivesicular bodies with the plasma membrane in exosome secretion.
STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion.
SNAP23 decreases insulin secretion by competitively inhibiting the interaction between SNAP25 and STX1A.
Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.
High sodium promotes the secretion and synthesis of PTH through PiT-1-IKKβ pathway in parathyroid gland in vitro.
P2X7 receptor-mediated depression-like reactions arising in the mouse medial prefrontal cortex.
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Astrocytic N-Methyl-D-Aspartate Receptors Protect the Hippocampal Neurons Against Amyloid-β142-Induced Synaptotoxicity by Regulating Nerve Growth Factor.
Transglutaminase 2 crosslinks zona pellucida glycoprotein 3 to prevent polyspermy.
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.
Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer.
Knockdown of astrocytic Grin2a aggravates β-amyloid-induced memory and cognitive deficits through regulating nerve growth factor.
PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode.
SNAP25/syntaxin4/VAMP2/Munc18-1 Complexes in Spinal Dorsal Horn Contributed to Inflammatory Pain.
RAB27B-activated secretion of stem-like tumor exosomes delivers the biomarker microRNA-146a-5p, which promotes tumorigenesis and associates with an immunosuppressive tumor microenvironment in colorectal cancer.
KRAS regulation by small non-coding RNAs and SNARE proteins.
Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3.
Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures.
Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands.
Zhang H, Song X, Ge S, Song W, Wang F, Yin Q, Zhang M, Zhuang P, Zhang Y
Journal of ethnopharmacology 2024 Sep 15;331:118337
Journal of ethnopharmacology 2024 Sep 15;331:118337
Identification of the SNARE complex that mediates the fusion of multivesicular bodies with the plasma membrane in exosome secretion.
Liu C, Liu D, Wang S, Gan L, Yang X, Ma C
Journal of extracellular vesicles 2023 Sep;12(9):e12356
Journal of extracellular vesicles 2023 Sep;12(9):e12356
STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion.
Yang M, Jiang H, Ding C, Zhang L, Ding N, Li G, Zhang F, Wang J, Deng L, Liu J, Xu Y
Immunity 2023 May 9;56(5):1013-1026.e6
Immunity 2023 May 9;56(5):1013-1026.e6
SNAP23 decreases insulin secretion by competitively inhibiting the interaction between SNAP25 and STX1A.
Chen J, Wang Z, Wang T, Cheng J, Zhuang R, Wang W
Bioscience reports 2023 May 31;43(5)
Bioscience reports 2023 May 31;43(5)
Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.
Xie BW, Guan B, Chen W, Zhou M, Gu Q, Liu Y, Yan D
Archives of biochemistry and biophysics 2023 Jun;741:109605
Archives of biochemistry and biophysics 2023 Jun;741:109605
High sodium promotes the secretion and synthesis of PTH through PiT-1-IKKβ pathway in parathyroid gland in vitro.
Shen A, Wang Y, Ye G, Mao J, Zhang Q, Chen J
Clinical science (London, England : 1979) 2023 Jun 28;137(12):947-962
Clinical science (London, England : 1979) 2023 Jun 28;137(12):947-962
P2X7 receptor-mediated depression-like reactions arising in the mouse medial prefrontal cortex.
Ren WJ, Zhao YF, Li J, Rubini P, Yuan ZQ, Tang Y, Illes P
Cerebral cortex (New York, N.Y. : 1991) 2023 Jul 5;33(14):8858-8875
Cerebral cortex (New York, N.Y. : 1991) 2023 Jul 5;33(14):8858-8875
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Liu N, Li M, Liu S, Kang J, Chen L, Huang J, Wang Y, Chen H, Zhang W
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
Astrocytic N-Methyl-D-Aspartate Receptors Protect the Hippocampal Neurons Against Amyloid-β142-Induced Synaptotoxicity by Regulating Nerve Growth Factor.
Song Y, Du Z, Chen X, Zhang W, Zhang G, Li H, Chang L, Wu Y
Journal of Alzheimer's disease : JAD 2022;85(1):167-178
Journal of Alzheimer's disease : JAD 2022;85(1):167-178
Transglutaminase 2 crosslinks zona pellucida glycoprotein 3 to prevent polyspermy.
Cui Z, Lu Y, Miao Y, Dai X, Zhang Y, Xiong B
Cell death and differentiation 2022 Aug;29(8):1466-1473
Cell death and differentiation 2022 Aug;29(8):1466-1473
Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.
Liu C, Zhou X, Long Q, Zeng H, Sun Q, Chen Y, Wu D, Liu L
Oncogene 2021 Jan;40(2):233-245
Oncogene 2021 Jan;40(2):233-245
Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer.
Liu YD, Zhuang XP, Cai DL, Cao C, Gu QS, Liu XN, Zheng BB, Guan BJ, Yu L, Li JK, Ding HB, Yan DW
Journal of experimental & clinical cancer research : CR 2021 Jan 14;40(1):31
Journal of experimental & clinical cancer research : CR 2021 Jan 14;40(1):31
Knockdown of astrocytic Grin2a aggravates β-amyloid-induced memory and cognitive deficits through regulating nerve growth factor.
Du Z, Song Y, Chen X, Zhang W, Zhang G, Li H, Chang L, Wu Y
Aging cell 2021 Aug;20(8):e13437
Aging cell 2021 Aug;20(8):e13437
PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode.
Serrano-López EM, López-Martínez D, Gómez-Fernández JC, Egea-Jiménez AL, Corbalán-García S
International journal of biological macromolecules 2021 Aug 31;185:377-389
International journal of biological macromolecules 2021 Aug 31;185:377-389
SNAP25/syntaxin4/VAMP2/Munc18-1 Complexes in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Duan XL, Guo Z, He YT, Li YX, Liu YN, Bai HH, Li HL, Hu XD, Suo ZW
Neuroscience 2020 Mar 1;429:203-212
Neuroscience 2020 Mar 1;429:203-212
RAB27B-activated secretion of stem-like tumor exosomes delivers the biomarker microRNA-146a-5p, which promotes tumorigenesis and associates with an immunosuppressive tumor microenvironment in colorectal cancer.
Cheng WC, Liao TT, Lin CC, Yuan LE, Lan HY, Lin HH, Teng HW, Chang HC, Lin CH, Yang CY, Huang SC, Jiang JK, Yang SH, Yang MH, Hwang WL
International journal of cancer 2019 Oct 15;145(8):2209-2224
International journal of cancer 2019 Oct 15;145(8):2209-2224
KRAS regulation by small non-coding RNAs and SNARE proteins.
Che Y, Siprashvili Z, Kovalski JR, Jiang T, Wozniak G, Elcavage L, Khavari PA
Nature communications 2019 Nov 11;10(1):5118
Nature communications 2019 Nov 11;10(1):5118
Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3.
Kimura H, Arasaki K, Ohsaki Y, Fujimoto T, Ohtomo T, Yamada J, Tagaya M
Journal of lipid research 2018 May;59(5):805-819
Journal of lipid research 2018 May;59(5):805-819
Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures.
Piotrowska A, Popiolek-Barczyk K, Pavone F, Mika J
Frontiers in cellular and infection microbiology 2017;7:141
Frontiers in cellular and infection microbiology 2017;7:141
Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands.
Yasui T, Gomi H, Kitahara T, Tsukise A
European journal of histochemistry : EJH 2017 Aug 8;61(3):2828
European journal of histochemistry : EJH 2017 Aug 8;61(3):2828
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 10825-1-AP(SNAP23 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using SNAP23 antibody 10825-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 10825-1-AP(SNAP23 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue