Tissue expression
Cell line expression
Protein structure
SNAP23
Synaptosome associated protein 23HsT17016, SNAP23A, SNAP23B
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Proteintech Group | 10825-1-AP | 20 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Invitrogen Antibodies | 10825-1-AP | Polyclonal |
WB
ICC
IP
IHC
FC
OA |
||
LSBio | LS-C133573 | Monoclonal |
WB
EL
IP
IHC |
||
NSJ Bioreagents | RQ7206 | Polyclonal |
WB
EL
ICC
IHC
FC
|
||
NovoPro Bioscience Inc. | 115444 | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider