MA1-21830

antibody from Invitrogen Antibodies

Targeting: PIK3R1 GRB1, p85, p85-ALPHA

Western blot (Recommended by provider)

Antibody Data

Product number

MA1-21830

Provider

Invitrogen Antibodies

Product name

PI3K p85 alpha Monoclonal Antibody (8-2D-4D)

Antibody type

Monoclonal

Antigen

Purifed from natural sources

Description

Recommended positive controls: Jurkat or A431 cells. By Western Blot this antibody detects a band of 85kDa, which corresponds to the predicted molecular weight of PI 3 kinase.

Reactivity

Human, Mouse, Rat

Host

Mouse

Isotype

IgG

Antibody clone number

8-2D-4D

Vial size

500 µL

Concentration

0.2 mg/mL

Storage

4° C, do not freeze

References

Submitted references

Phosphatidylinositol 4,5-bisphosphate mediates Ca2+-induced platelet alpha-granule secretion: evidence for type II phosphatidylinositol 5-phosphate 4-kinase function.

Rozenvayn N, Flaumenhaft R
The Journal of biological chemistry 2001 Jun 22;276(25):22410-9

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Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants.

Gille H, Kowalski J, Li B, LeCouter J, Moffat B, Zioncheck TF, Pelletier N, Ferrara N
The Journal of biological chemistry 2001 Feb 2;276(5):3222-30

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A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration.

Gille H, Kowalski J, Yu L, Chen H, Pisabarro MT, Davis-Smyth T, Ferrara N
The EMBO journal 2000 Aug 1;19(15):4064-73