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Protein structure
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1GRB1, p85, p85-ALPHA
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Top validated antibodies |
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| antibodies-online |  ABIN1098111 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| GeneTex | GTX60633 |
1 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Novus Biologicals | NBP2-22212 |
1 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
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| Proteintech Group | 60225-1-Ig |
164 references | Monoclonal |
WB
EL
IP
IHC
|
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| Abnova Corporation | H00005295-M01 |
1 references | Monoclonal |
WB
EL
IP
PLA
|
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