Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- M00151 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-FAK PTK2 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for FAK/PTK2 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat FAK/PTK2 information: Molecular Weight: 119233 MW; Subcellular Localization: Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus. Constituent of focal adhesions. Detected at microtubules; Tissue Specificity: Detected in B and T-lymphocytes. Isoform 1 and isoform 6 are detected in lung fibroblasts (at protein level). Ubiquitous.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- DDD-16
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references Transcription factor Runx2 changes the expression of some matricellular proteins in metastatic breast cancer cells.
Effect of celecoxib on protein expression of FAK and Cx43 in DMBA induced rat tongue carcinoma cells.
Multilayered coating of titanium implants promotes coupled osteogenesis and angiogenesis in vitro and in vivo.
Research of shRNAmir inhibitory effects towards focal adhesion kinase expression in the treatment of gastric cancer.
Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis.
Binay S, Kaptan E
Molecular biology reports 2022 Jul;49(7):6433-6441
Molecular biology reports 2022 Jul;49(7):6433-6441
Effect of celecoxib on protein expression of FAK and Cx43 in DMBA induced rat tongue carcinoma cells.
Shan BZ, Guo B, Li YS, Sun XF
European review for medical and pharmacological sciences 2019 Nov;23(21):9454-9463
European review for medical and pharmacological sciences 2019 Nov;23(21):9454-9463
Multilayered coating of titanium implants promotes coupled osteogenesis and angiogenesis in vitro and in vivo.
Chen W, Xu K, Tao B, Dai L, Yu Y, Mu C, Shen X, Hu Y, He Y, Cai K
Acta biomaterialia 2018 Jul 1;74:489-504
Acta biomaterialia 2018 Jul 1;74:489-504
Research of shRNAmir inhibitory effects towards focal adhesion kinase expression in the treatment of gastric cancer.
Su GQ, Zhang FX, Mao HH, Liu XW, Zheng YS, Zhang SY, Su JJ
Oncology letters 2015 Feb;9(2):595-603
Oncology letters 2015 Feb;9(2):595-603
Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis.
Cao T, Xing Y, Yang Y, Mei H
Experimental and therapeutic medicine 2014 Jan;7(1):280-286
Experimental and therapeutic medicine 2014 Jan;7(1):280-286
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded mouse spleen, using FAK Antibody(M00151)PTK2 was detected in paraffin-embedded tissue section. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-PTK2 Antibody (M00151)overnight at 4
- Additional image