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Protein structure
PTK2
Protein tyrosine kinase 2FADK, FAK, FAK1, PPP1R71
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
Top validated antibodies |
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| Invitrogen Antibodies |  700255 |
42 references | Monoclonal |
WB
EL
ICC
IHC
FC
OA
|
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| Proteintech Group | 12636-1-AP |
92 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
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| GeneTex | GTX24803 |
5 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
|
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| Boster Biological Technology | M00151 |
5 references | Monoclonal |
WB
ICC
IP
IHC
FC
|
|
| Novus Biologicals | NBP2-67327 |
1 references | Monoclonal |
WB
ICC
IP
IHC
FC
|
|
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