Ab102794

antibody from Aladdin Scientific

Targeting: PTK2 FADK, FAK, FAK1, PPP1R71

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Validation data

Product number: Ab102794 - Provider product page
Provider: Aladdin Scientific
Product name: FAK Antibody
Antibody type: Polyclonal
Description: Rabbit anti Human FAK Antibody, Polyclonal, could be used for WB, IHC and so on.ApplicationWB: 0.5-2 µg/mLIHC: 5-20 µg/mLProtein FunctionNon-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 798-1041
Vial size: 100_l,10_l,1ml,20_l,50_l
Concentration: Lot by Lot
Storage: Store at 4_ short term (1-2 weeks). Store at -20_ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

PTK2 protein structure - Ab102794 shown in red.