ABIN361988

antibody from antibodies-online

Targeting: PTK2 FADK, FAK, FAK1, PPP1R71

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN361988

Provider

antibodies-online

Product name

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr861) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pTyr861 (H-I-Y (p) -Q-P) derived from Human FAK. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pTyr861

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397.

Shi Q, Boettiger D
Molecular biology of the cell 2003 Oct;14(10):4306-15

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Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215.

Vadlamudi RK, Sahin AA, Adam L, Wang RA, Kumar R
FEBS letters 2003 May 22;543(1-3):76-80

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Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.

Eliceiri BP, Puente XS, Hood JD, Stupack DG, Schlaepfer DD, Huang XZ, Sheppard D, Cheresh DA
The Journal of cell biology 2002 Apr 1;157(1):149-60

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Secretion by the Renal Tubules in the Frog.

Bainbridge FA, Beddard AP
The Biochemical journal 1906;1(6-7):255-73