ABIN362753

antibody from antibodies-online

Targeting: PTK2 FADK, FAK, FAK1, PPP1R71

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362753

Provider

antibodies-online

Product name

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 923-927) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 923-927 (K-V-Y-E-N) derived from Human FAK. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 923-927

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling.

Cherubini A, Hofmann G, Pillozzi S, Guasti L, Crociani O, Cilia E, Di Stefano P, Degani S, Balzi M, Olivotto M, Wanke E, Becchetti A, Defilippi P, Wymore R, Arcangeli A
Molecular biology of the cell 2005 Jun;16(6):2972-83

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p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV.

Sanders MA, Basson MD
The Journal of biological chemistry 2005 Jun 24;280(25):23516-22

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A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397.

Shi Q, Boettiger D
Molecular biology of the cell 2003 Oct;14(10):4306-15

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Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase.

Toriumi Y, Hiraoka M, Watanabe M, Yoshida M
FEBS letters 2003 Oct 23;553(3):419-22