BS7227

antibody from Bioworld Technology, Inc

Targeting: UHRF1 FLJ21925, ICBP90, Np95, RNF106, TDRD22

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Chromatin Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

BS7227

Provider

Bioworld Technology, Inc

Product name

UHRF1 polyclonal antibody (ChIP Grade)

Antibody type

Polyclonal

Antigen

Recombinant full length Human UHRF1.

Description

UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5-CCAAT-3 box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1s ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Western blot

Supportive validation

Submitted by

Bioworld Technology, Inc (provider)

Main image

Experimental details

Western blot analysis of UHRF1 polyclonal antibody