MB0055

antibody from Bioworld Technology, Inc
Targeting: UHRF1 FLJ21925, ICBP90, Np95, RNF106, TDRD22
Provider product page for MB0055

Antibody data

Product number
MB0055 - Provider product page
Provider
Bioworld Technology, Inc
Product name
UHRF1 (N terminus) monoclonal antibody
Antibody type
Monoclonal
Antigen
Synthetic peptide, corresponding to the N-terminus of Human UHRF1.
Description
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Mouse
Host
Mouse
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
UHRF1 protein structure - MB0055 shown in red.