Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB1379 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB1379, RRID:AB_1712273
- Product name
- PTPN6 monoclonal antibody, clone M160
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant PTPN6.
- Isotype
- IgG
- Antibody clone number
- M160
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus.
The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation.
Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling.
Jones ML, Craik JD, Gibbins JM, Poole AW
The Journal of biological chemistry 2004 Sep 24;279(39):40475-83
The Journal of biological chemistry 2004 Sep 24;279(39):40475-83
The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation.
Zhang Z, Shen K, Lu W, Cole PA
The Journal of biological chemistry 2003 Feb 14;278(7):4668-74
The Journal of biological chemistry 2003 Feb 14;278(7):4668-74
Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling.
Zhang J, Somani AK, Siminovitch KA
Seminars in immunology 2000 Aug;12(4):361-78
Seminars in immunology 2000 Aug;12(4):361-78
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of human Jurkat cells treated with pervanadate (1 mM) for 30 min (lane 1 & 2). The blot was exposed to lambda phosphatase (lane 2) then probed with PTPN6 monoclonal antibody, clone M160 (Cat # MAB1379).