PTPN6

gene product
HCP, HCPH, PTP-1C, SHP-1, SHP1
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
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704 antibodies from 42 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Novus Biologicals
10 antibodies
Invitrogen Antibodies
15 antibodies
GeneTex
15 antibodies
antibodies-online
196 antibodies
Proteintech Group
1 antibody
Biorbyt
37 antibodies
OriGene
27 antibodies
NovoPro Bioscience Inc.
12 antibodies
Acris Antibodies GmbH
25 antibodies
Abnova Corporation
21 antibodies
Signalway Antibody LLC
2 antibodies
Abgent
9 antibodies
Santa Cruz Biotechnology
1 antibody
LifeSpan BioSciences, Inc.
73 antibodies
Bioworld Technology, Inc
3 antibodies
Affinity Biosciences
6 antibodies
Aviva Systems Biology
8 antibodies
ProSci
7 antibodies
Boster Biological Technology
2 antibodies
Arigo
7 antibodies
Cell Signaling Technology, Inc
2 antibodies
St John's Laboratory
11 antibodies
RabMAbs
5 antibodies
Antibodies.com
2 antibodies
Bethyl Laboratories
1 antibody
Abbkine Scientific Co.Ltd.
4 antibodies
Everest Biotech
2 antibodies
NSJ Bioreagents
2 antibodies
Creative Biolabs
5 antibodies
MyBioSource
11 antibodies
Creative Diagnostics
4 antibodies
Abbiotec
1 antibody
United States Biological
94 antibodies
GenWay
6 antibodies
RayBiotech, Inc.
3 antibodies
Abiocode, Inc.
1 antibody
EMD Millipore
4 antibodies
Abbexa
3 antibodies
Sigma-Aldrich
4 antibodies
Exalpha Biologicals, Inc.
1 antibody