PAB7927

antibody from Abnova Corporation

Targeting: PTPN6 HCP, HCPH, PTP-1C, SHP-1, SHP1

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB7927

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB7927, RRID:AB_1712281

Product name

PTPN6 (phospho S591) polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of PTPN6.

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells.

Simoneau M, Boulanger J, Coulombe G, Renaud MA, Duchesne C, Rivard N
The Journal of biological chemistry 2008 Sep 12;283(37):25544-56

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Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus.

Jones ML, Craik JD, Gibbins JM, Poole AW
The Journal of biological chemistry 2004 Sep 24;279(39):40475-83

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The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation.

Zhang Z, Shen K, Lu W, Cole PA
The Journal of biological chemistry 2003 Feb 14;278(7):4668-74

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of human Jurkat cells treated with pervanadate (1 mM) for 30 min (lanes 1 & 2). The blot was exposed to lambda phosphatase (lane 2) and then probed with PTPN6 (phospho S591) polyclonal antibody (Cat # PAB7927).