AMAb90746

antibody from Atlas Antibodies

Targeting: MRC1 bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

AMAb90746

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#AMAb90746, RRID:AB_2665652

Product name

Anti-MRC1

Antibody type

Monoclonal

Description

Monoclonal Antibody against Human MRC1, Clone ID: CL0387, Gene description: mannose receptor, C type 1, Alternative Gene Names: bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1, Validated applications: WB, IHC, Uniprot ID: P22897, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

CL0387

Vial size

100 µl

Concentration

1.0 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Mast-cell expressed membrane protein-1 is expressed in classical monocytes and alveolar macrophages in idiopathic pulmonary fibrosis and regulates cell chemotaxis, adhesion, and migration in a TGFβ-dependent manner

Perrot C, Karampitsakos T, Unterman A, Adams T, Marlin K, Arsenault A, Zhao A, Kaminski N, Katlaps G, Patel K, Bandyopadhyay D, Herazo-Maya J
American Journal of Physiology-Cell Physiology 2024;326(3):C964-C977

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Liraglutide Therapy in Obese Patients Alters Macrophage Phenotype and Decreases Their Tumor Necrosis Factor Alpha Release and Oxidative Stress Markers—A Pilot Study

Bułdak Ł, Bołdys A, Skudrzyk E, Machnik G, Okopień B
Metabolites 2024;14(10):554

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Nasim S, Bichsel C, Pinto A, Alexandrescu S, Kozakewich H, Bischoff J
2024

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TRPV1+ neurons alter Staphylococcus aureus skin infection outcomes by affecting macrophage polarization and neutrophil recruitment

Huang C, Chen Y, Cai Y, Ding H, Hong J, You S, Lin Y, Hu H, Chen Y, Hu X, Chen Y, Huang Y, Zhang C, Lin Y, Huang Z, Li W, Zhang W, Fang X
BMC Immunology 2023;24(1)

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Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma

Lee A, Sun L, Mochizuki A, Reynoso J, Orpilla J, Chow F, Kienzler J, Everson R, Nathanson D, Bensinger S, Liau L, Cloughesy T, Hugo W, Prins R
Nature Communications 2021;12(1)

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Evaluation of Glycosylated PTGS2 in Colorectal Cancer for NSAIDS-Based Adjuvant Therapy

Venè R, Costa D, Augugliaro R, Carlone S, Scabini S, Casoni Pattacini G, Boggio M, Zupo S, Grillo F, Mastracci L, Pitto F, Minghelli S, Ferrari N, Tosetti F, Romairone E, Mingari M, Poggi A, Benelli R
Cells 2020;9(3):683

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Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining

Saylor J, Ma Z, Goodridge H, Huang F, Cress A, Pandol S, Shiao S, Vidal A, Wu L, Nickols N, Gertych A, Knudsen B
Frontiers in Immunology 2018;9

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human lung and skeletal muscle tissues using AMAb90746 antibody. Corresponding MRC1 RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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