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Learn18704-1-AP
antibody from Proteintech Group
Targeting: MRC1
bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [940]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 18704-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18704-1-AP, RRID:AB_10597232
- Product name
- CD206 antibody
- Antibody type
- Polyclonal
- Description
- CD206 antibody (Cat. #18704-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Effects of bromelain, melatonin, and thymoquinone on neutrophil extracellular trap formation and macrophage polarization in experimental periodontitis.
Photocrosslinkable Chitosan Quaternary Ammonium Salt-Based Ternary Hydrogel with Fibroblast Growth Factor 21 for Diabetic Wound Healing.
Bioactive Platinum Nanozymes Accelerate Diabetic Wound Healing via Anti-Inflammation and Macrophage Polarization Modulation.
After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway.
Platelet-rich plasma-derived microRNA let-7a-5p alleviates knee osteoarthritis by regulating macrophage polarization and improving inflammatory microenvironment.
RP-182 alleviated obstruction-induced renal fibrosis by reprogramming CD206(+) macrophages.
The prognostic significance of JAML and its role in remodeling the immune microenvironment via the cGAS-STING pathway in endometrial cancer.
GCDCA promotes hepatocellular carcinoma progression through S1PR2/PI3K/AKT-mediated polarization of M2-type macrophages.
Prognostic integration of tumor microenvironment and parthanatos-related genes in gastric cancer: a machine learning-driven risk model and immune landscape profiling.
CD146(+) pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis.
Electroacupuncture reduces calcium influx and inhibits endoplasmic reticulum stress by inhibiting the PKCδ-TRPA1 pathway to promote motor function recovery after spinal cord injury.
Aspirin-induced mesenchymal stem cell-derived extracellular vesicles promote osteochondral regeneration by reprogramming macrophages.
ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.
PRSS23 functions downstream of ZEB1 to promote esophageal squamous cell carcinoma progression by driving M2 polarization of tumor associated macrophages.
Antimicrobial peptide chensinin-1b attenuates T2DM progression in atherosclerotic ApoE(-/-) mice.
Salt-triggered electroactive dressing with controlled drug release for enhanced healing of exudative wounds.
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Macrophage Membrane-Cloaked, ROS-Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome.
Dietary N-acetylneuraminic acid maintains intestinal homeostasis and protects against aging- and inflammation-associated colonic dysfunction.
Pomegranate-inspired bionic microgel/periosteum composite harnessing reactive oxygen species for immune-engineered bone regeneration.
Huangtu Decoction regulates macrophage M1/M2 polarization to alleviate DSS- and rhubarb-induced Deficiency-Cold Pattern in Ulcerative Colitis by inhibiting the HIF-1α signaling pathway.
Integrative epidemiology and multi-omics reveal a frailty-associated ACKR1 redox axis linking cadmium exposure to atherosclerosis.
Activated ATF6α is a hepatic tumour driver restricting immunosurveillance.
Immune regulative GelMA&Zn(2+)/Ce(3+)-whitlockite scaffolds with continuous ions release for bone regeneration.
Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1.
SIRT6 Ameliorates Atherosclerosis by Inhibiting M1 Macrophage Polarisation Through Deacetylated-TLR4.
Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage.
ZXDB Drives Macrophage Inflammatory Programming in Sepsis-Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation.
Cordycepin alleviates ischaemic brain injury by suppressing microglia-induced neuroinflammation via regulating the Notch1 signalling pathway.
Silencing soluble epoxide hydrolase protects against myocardial ischemia-reperfusion injury through modulation of the YAP signaling pathway and macrophage polarization.
CX3CL1/CX3CR1 axis dysregulation contributes to epileptogenic mechanisms in focal cortical dysplasia.
Exercise reverses high-fat diet-induced perivascular adipose tissue dysfunction through modulation of UCP2 and TXNIP/NLRP3 pathways.
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Repeated inhalation exposure to polystyrene nanoplastics induced sustained pulmonary injury and fibrosis in mice.
Dynamically responsive hydrogel with mechanical stimulation enhances diabetic wound healing via activation of Piezo1-mediated efferocytosis.
Lung cancer cell-derived exosomal EHF drives M2 macrophage polarization via transcriptional activation of RNF41 to promote tumor progression.
Rhubarb ameliorates ischemic stroke-induced tryptophan-kynurenine metabolic reprogramming and neuroinflammation via modulation of the IDO-1/TREM-1 pathway.
Dehydroandrographolide succinate alleviates ulcerative colitis via regulating RAB9A/NF-κB axis-mediated macrophage polarization and remodeling the gut microbiota.
Celastrol ameliorates depressive-like behaviors in a rat model of post-stroke depression and is associated with reduced neuroinflammation and restoration of serotonergic- and synaptic-related proteins.
Spatiotemporally engineered microneedle for microenvironment remodeling propels mucosal regeneration after tracheal mucosal injury.
Shaoyao Gancao Decoction alleviates ulcerative colitis-associated secondary liver injury by inhibiting the phosphorylation of pyruvate dehydrogenase in macrophages.
The role of the IL-33/ST2/MAPK signalling pathway in macrophage polarisation and endometrial fibrosis.
CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis.
Multimerin-1 modulates macrophage M2 polarization and enhances tumor cell stemness in glioblastoma.
Downregulation of the biological macromolecule Spondin-2 disrupts maternal-fetal immune tolerance and trophoblast invasion, driving unexplained recurrent pregnancy loss.
Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty acid synthesis halts pro-fibrotic M2 polarization.
SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.
Salidroside ameliorates experimental autoimmune neuritis by dually modulating neuroinflammation and immune homeostasis via PI3K/AKT signaling.
Nanoparticle-Modified Nanofibers Induce Ferroptosis and Stimulate Antitumor Immunity for Melanoma Therapy.
Ferroptosis-dependent small extracellular vesicles ULK1 enhances mitophagy and suppresses breast cancer migration.
Single-cell transcriptomics uncover RNF130-mediated TNF-α pathway activation and worenine synergy with paclitaxel in breast cancer.
Rewiring brain structural and functional disconnection with acupuncture in rat model of vascular cognitive impairment and dementia.
Acupuncture as a modulator of microglial polarization and pyroptosis in depression: evidence from a chronic unpredictable mild stress rat model.
Explore the chemical components of Angong Niuhuang Pill and its potential mechanisms for fever treatment based on UHPLC-Q-Exactive orbitrap HRMS, transcriptomics, and experiment verification.
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
Lithospermic acid regulates macrophage polarization via AMPKα1 activation and ameliorates sepsis associated acute kidney injury in mice.
Transcutaneous Auricular Vagus Nerve Stimulation Ameliorates Heart Failure with Preserved Ejection Fraction Through Regulating Macrophage Polarization Mediated by Alpha7nAChR.
Self-regulating neohesperidin/silk fibroin composite aerogel for enhanced wound healing via pH-responsive release.
Clicktetrazine dECM-alginate hydrogels for injectable, mechanically mimetic, and biologically active vocal fold biomaterials.
Programmed temporal modulation by using a magnetoelectric wound dressing for ultra-fast early-stage wound healing.
Blastocyst Structure-Inspired Core-Shell Stem Cell Microspheres with Hyperoside Delivery for Endometrial Regeneration.
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Construction of a Novel Mucin/Tannic Acid Hydrogel for Diabetic Wound Repair.
Kaempferol Alleviates Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Modulating Macrophage M1/M2 Polarization Through RhoA/ROCK-Mediated Mitophagy Activation.
Nanoengineered extrusion-aligned tract bioprinting enables functional repair of spinal cord injuries.
AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPK-MTOR-autophagy pathway in macrophage.
Functional border-associated macrophages limit Alzheimer's Disease progression.
Succinate Mediates Immune-Angiogenic Response by Activating Macrophage M2 Polarization in Oxygen-Induced Retinopathy.
Targeting FAM83D triggers tumor cell senescence via cGAS-STING signaling activation and reprograms TAMs to combat glioma.
Simulated microgravity affects neuronal synaptic plasticity by regulating microglial pro-inflammatory activation.
Biomimetic Selenium-Encrusted Prussian Blue Nanozyme for Myocardial Infarction by Coordinated Enhancement of Mitophagy and Reactive Oxygen Species Scavenging.
IL-37 Ameliorates Chronic Endometritis by Attenuating Epithelial-Mesenchymal Transition and Promoting M2 Macrophage Polarization.
The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.
NIR-II-Responsive Biomimetic Nanoplatform for Precise Inhibition of Ischemic Stroke via Dual Modulation of Ion Channels and Microglia.
Synthetic cleavage-resistant TREM2 boosts macrophage efferocytosis to treat inflammatory diseases.
Carbon-based nanomaterials induce ovarian dysfunction via NLRP3 inflammasome-mediated pyroptosis in granulosa cells.
Targeting VEGFR2 inhibition within a spatially-confined conduit promotes nerve self-resolution and alleviates mechanical allodynia.
Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy.
Mossy-textured hydroxyapatite-modified poly (lactic-co-glycolic acid) microspheres promote collagen regeneration via calcium/TGF-β and chemokine signaling pathways in soft tissue augmentation.
HMGA2 promotes hepatocellular carcinoma progression by regulating tumor-associated macrophage via Notch1/CCL2 signaling.
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
The multilayer coatings on polylactic acid implants spatiotemporally regulates the microenvironment to enhance antibacterial and osseointegration capacity.
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Polyhedral oligomeric silsesquioxane-functionalized carboxymethyl chitin microspheres via irradiation-induced grafting for hemostasis and tissue repair in post-extraction sockets.
Morphologically adaptive microconical hydrogels of gelatin/polyvinyl alcohol with curcumin for diabetic wound repair.
3D perfusable minichannels stented with matrix bound vesicles derived from gingival mesenchymal stem cells ameliorated granuloma-related stenosis and improved survival in a rabbit tracheal replacement model.
ANGPT2/Tie2 Enhances H3K18la-Mediated Macrophage M2 Polarization to Promote Endothelial Cell Proliferation in the Chronically Ischaemic Brain.
Wine-Processed Cornus officinalis Ameliorates Osteoarthritis via Modulating M1/M2 Macrophage Polarization.
Parthenolide ameliorates inflammation in sepsis via covalently targeting Trim33 and inhibiting NF-κB pathway.
Sulforaphane ameliorates DSS-induced colitis and secondary liver injury in mice: Proposed mechanism in the SCFAs-FFAR2/3-macrophage polarization axis.
Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression.
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Histochemical characterization of muscularis macrophage loss and disruption of a miR-93-5p-AHNAK neuro-immune axis in Hirschsprung's disease.
Aerobic Exercise Alleviates Oxidative Stress and Inflammation to Attenuate High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in ApoE(-/-) Mice.
Targeting keratin 6 A overcomes gemcitabine resistance by restoring equilibrative nucleoside transporter 1 and TAM-mediated metabolic compensation in pancreatic cancer.
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
A pH-Responsive Polyetheretherketone Implant Modified with a Core-Shell Metal-Organic Framework to Promote Antibacterial and Osseointegration Abilities.
The Extracellular Matrix Promotes Diabetic Oral Wound Healing by Modulating the Microenvironment.
IL-1β-Stimulated Bone Mesenchymal Stem Cell-Derived Exosomes Mitigate Sepsis through Modulation of HMGB1/AKT Pathway and M2 Macrophage Polarization.
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Chaperonins in Hepatocellular Carcinoma: Unveiling Their Role in Tumor Proliferation and Immune Modulation Through Multiomics Analysis.
TGF-β-Smad2/3 signaling in high-altitude pulmonary hypertension in rats: Role and mechanisms via macrophage M2 polarization.
Prussian Blue Nanoparticle-Induced Alteration of the Polarization State of Tumor-Associated Macrophages as a Substantial Antitumor Mechanism Against Oral Squamous Cell Carcinoma (OSCC).
Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy.
Reduced Thioredoxin Regulates IL-1β Secretion via NLRP3 of IL-1β+ Alveolar Macrophages in COPD.
Ginger Moxibustion Activates TRPV1 to Modulate the Locus Coeruleus-Spinal Cord-Uterus Pathway and Alleviates Primary Dysmenorrhea in Rats.
Mechanistic Study of CD90-Positive Synovial Fibroblasts in the Invasion and Recurrence of Pigmented Villonodular Synovitis.
Altered Expression of CXCL16/CXCR6 and Its Correlation with Decidual Macrophage Polarization in Preeclampsia.
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
TENS alleviates CP/CPPS-related inflammation and pain by modulating Kir2.1-dependent macrophage polarization.
Serglycin's role in primary liver cancer: insights into tumor microenvironment and macrophage interaction.
Bone marrow mesenchymal stem cells alleviate smoke inhalation injury by regulating alveolar macrophage polarization via the CD200-CD200R pathway.
Resistance training alleviates muscle atrophy and muscle dysfunction by reducing inflammation and regulating compromised autophagy in aged skeletal muscle.
Cordycepin, lactoferrin, and Sargassum fusiforme polysaccharides protects against RSV via M2-like macrophage polarization.
Ganoderma lucidum spore powder alleviates rheumatoid arthritis-associated pain hypersensitivity through inhibiting accumulation, N1 polarization, and ROS production of neutrophils in mice.
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Prognostic significance and immune infiltration analysis of HMGA2 in endometrial cancer.
Hydrogen sulfide as a therapeutic agent for diabetic wounds: effects on inflammation and fibroblast pyroptosis.
Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfusion injury.
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment.
Bioinspired exosome-SiO(2) nanohybrid therapeutic for rheumatoid arthritis treatment.
Polyphenol and metal ion-reinforced supermolecular hydrogels incorporating nanofiber drug and peptide for annulus fibrosus regeneration.
Pathological and immune features of non-tuberculous mycobacteria and Mycobacterium tuberculosis cutaneous/mucosa infections of fifty-four biopsies.
Ansofaxine Hydrochloride inhibits hepatocellular carcinoma growth and enhances targeted therapy through the EGFR/MAPK pathway.
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
A multifunctional dihydromyricetin-loaded hydrogel for the sequential modulation of diabetic wound healing and glycemic control.
Exosome-related immune signatures and peripheral blood assays predict prognosis and immunotherapy response in hepatocellular carcinoma.
The effect of ponicidin on CFA-induced chronic inflammatory pain and its mechanism based on network pharmacology and molecular docking.
Metabolic reprogramming of tumor-associated macrophages via adenosine-A(2A)R signaling drives cross-resistance in non-small cell lung cancer.
Tremella fuciformis Polysaccharides Alleviate Early Brain Injury in Experimental Subarachnoid Hemorrhage by Inhibiting the KDR-Mediated P38 MAPK/NF-κB Pathway.
Engineered nerve guide conduit enhances peripheral nerve regeneration by modulating the microenvironment through macrophage-triggered cascade reactions.
Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere.
Peptide-Enhanced Bioactive Hydrogel Combined with Photodynamic-Phage Synergistic Antibacterial Therapy System Accelerates Infected Wound Healing.
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Electroacupuncture promotes myelin repair in the corpus callosum region of cerebral ischemic rats by modulating microglia activation and polarization.
Isoacteoside alleviates LPS-induced depressive-like behaviors in mice by inhibiting neuroinflammation through regulating microglial polarization and oxidative stress.
Tongqiao huoxue decoction in improving vascular cognitive impairment in rats through PI3K-AKT pathway.
RHBDF2 governs microglial neuroinflammation during cerebral ischemia-reperfusion injury and is positively regulated by the m6A reader YTHDF1.
Microenvironment responsive nanoplatform for targeted removal of cholesterol and reshaping inflammatory microenvironment in atherosclerotic plaques.
Polyphyllin I enhances the anti-tumor efficacy of Palbociclib by reversing M2 macrophage polarization in lung cancer.
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
Dual stimulus-responsive dECM cryogel sequentially regulate bone microenvironment for one-step surgical therapy of chronic osteomyelitis.
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Orally-deliverable liposome-microgel complexes dynamically remodel intestinal environment to enhance probiotic ulcerative colitis therapy via TLR4 inhibition and tryptophan metabolic crosstalk.
Columbianadin targets TRIM7 to maintain P2X7 palmitoylation, inhibiting cuproptosis in synovial M2 macrophages.
PDPK1 governs macrophage M2 polarization via hypoxia-driven CD47/AKT-glycolytic Axis in endometriosis.
Effects of higenamine on M1/M2 polarization and osteoclast differentiation in rheumatoid arthritis via the THBS-1/TGF-β signaling pathway.
miR-21-5p Alleviates Retinal Ischemia-Reperfusion Injury by Inhibiting M1 Polarization of Microglia via Suppression of STAT3 Signaling.
Injectable Immune-Regulating Mesenchymal Stem Cells Hydrogel for Localized Scleroderma Treatment.
Intratumoral microbiota-driven macrophage reprogramming in pancreatic cancer via Blautia metabolite 6-hydroxyhexanoic acid.
Hypoxia-Induced Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization and Enhance Angiogenesis to Promote Diabetic Wound Healing.
M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis.
Pterostilbene as a pyroptosis inducer and tumor microenvironment regulator inhibits glioblastoma and enhances the efficacy of immunotherapy.
TFAP4/DLGAP5 promotes tumor progression and macrophage M2 polarization in prostate cancer by activating the JAK2/STAT3 signaling.
The Crosstalk Between Sepsis-Associated Encephalopathy and Alzheimer's Disease: Identifying Potential Biomarkers and Therapeutic Targets for Cognition.
Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex.
Upregulation of ACSL1 in synovial macrophages promotes lipid peroxidation via the IκB/NF-κB pathway to accelerate osteoarthritis.
Isopimpinellin: A Promising Treatment for Colitis-Related Colorectal Cancer That Targets ALOX5-Mediated Macrophage Polarization.
Structural characterization and medium-chain acyl-coenzyme a dehydrogenase-mediated anti-inflammatory mechanism of a Hulless barley Monascus polysaccharide in ulcerative colitis.
Jolkinolide B Mitigates Cerebral Ischemia-Reperfusion Injury by Promoting Microglial M1/M2 Polarization Through the JAK2/STAT3 Signaling Pathway.
Dexmedetomidine alleviates sepsis-induced acute lung injury by inhibiting M1 macrophage polarization via inhibition of PKM2-mediated Warburg effect.
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Decoupling Half-Process Assisted Mitochondrial Transplantation via Self-Stripping pHLIP Boosts Macrophages Reprogramming for Inflammation Resolution.
AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
Protocatechuic aldehyde promotes diabetic wound healing by enhancing angiogenesis via H3K18 lactylation-mediated Acvr1c expression.
Evaluation of a novel bioceramic sealer NeoSEALER Flo on the activation and polarization of macrophage.
The Leupaxin/HDAC6/EGR2 axis facilitates breast cancer progression by enhancing macrophage M2 polarization.
A murine distal femoral epiphysis ischemia model reveals spatiotemporal stratification of necrotic bone marrow clearance and associated inflammatory responses.
Modified Xiaoyao San ameliorates LPS-induced depression-like behavior by inhibiting NLRP3-mediated microglial pyroptosis.
The miR-125a-5p/IRF4 Axis Mediates Sodium Arsenite-Induced M2 Macrophage Polarization.
11-keto-β-boswellic acid and Z-guggulsterone suppress HMGB1/TLR4 pathway activity and modulate microglial polarization to remodel perineuronal nets after nerve injury.
Omentin-1 reduced synovial M1 macrophages through SIRT6 signaling pathway and alleviated knee osteoarthritis response in mice.
Carnosine protects against cerebral ischemia/reperfusion injury through promoting microglial M2 polarization via SIRT1/NF-κB signaling pathway.
A hydrogel-based nanoparticles sustained-release system selectively targeting pro-inflammatory microglia for spinal cord injury repair.
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury.
Th22 cells promote the transition from homeostatic to reactive microglia in diabetic encephalopathy.
GIV/Girdin Modulation of Microglial Activation in Ischemic Stroke: Impact of FTO-Mediated m6A Modification.
Platelet activation stimulates macrophages to enhance ulcerative colitis through PF4/CXCR3 signaling.
Restoring tendon microenvironment in tendinopathy: Macrophage modulation and tendon regeneration with injectable tendon hydrogel and tendon-derived stem cells exosomes.
Hyaluronic acid-modified PtPdCo-CQ nanocatalyst with triple enzyme-like activities regulates macrophage polarization and autophagy levels for the treatment of rheumatoid arthritis.
Electroacupuncture alleviates diesel exhaust particles-induced inflammatory response in lung through dopamine inhibition of NLRP3 signaling pathway.
Temporal and spatial expression of Phosphodiesterase-4B after sciatic nerve compression in rats and its mechanism of action on sciatic nerve repair.
Mg(2+)-Loaded Black Phosphorus Nanosheet Protects against Cerebral Ischemic Injury through Anti-Oxidative and Anti-Inflammatory Effects.
Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose-Derived Stem Cells.
Myeloid but not hepatocytic CD38 is a key driver for hepatic ischemia/reperfusion injury.
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
Astragaloside III inhibits MAPK-mediated M2 tumor-associated macrophages to suppress the progression of lung Cancer cells via Akt/mTOR signaling pathway.
M2 macrophages activate the IL-10/JAK2/STAT3 pathway to induce pathological microangiogenesis in the nucleus pulposus exacerbating intervertebral disc degeneration.
Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response.
L-Kynurenine regulates immune response in ICIs-associated myocarditis via JAK/STAT pathway.
Therapeutic potential of ADSC-derived exosomes in acute lung injury by regulating macrophage polarization through IRF7/NLRP3 signaling.
M2-ApoBDs as a therapeutic strategy for systemic lupus erythematosus: targeted macrophage reprogramming and treg differentiation.
KLF15 regulates macrophage polarization patterns in deep vein thrombosis.
Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB.
IL-27 accelerates diabetic wound healing by modulating macrophage polarization.
Astragaloside IV prevents liver fibrosis by blocking glycolysis-mediated macrophage M1 polarization.
Chemotherapy-induced macrophage CXCL7 expression drives tumor chemoresistance via the STAT1/PHGDH-serine metabolism axis and SAM paracrine feedback to M2 polarization.
Bta-miR-93 regulates the maternal-fetal tolerance in dairy cows via promoting Programmed Cell Death Ligand 1 mediated M2 macrophage polarization†.
An active shrinkage and antioxidative hydrogel with biomimetic mechanics functions modulates inflammation and fibrosis to promote skin regeneration.
Multifunctional sericin-based biomineralized nanoplatforms with immunomodulatory and angio/osteo-genic activity for accelerated bone regeneration in periodontitis.
Conductive hyaluronic acid/phytanic acid hydrogel to deliver recombinant human amelogenin for diabetic wound repair.
Early intervention with pericyte Fli-1 post-TBI attenuates hippocampal BBB disruption and subsequent neuroinflammation with neurological deficits.
Immune checkpoint inhibitors mediate myocarditis by promoting macrophage polarization via cGAS/STING pathway.
Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.
Tetrahydroxy Stilbene Glycoside Reduces Abeta Deposition by Modulating Microglia Activation and via TREM2/PI3K/AKT Pathway in APP/PS1 Mice.
KLHDC8A knockdown in normal ovarian epithelial cells promoted the polarization of pro-tumoral macrophages via the C5a/C5aR/p65 NFκB signaling pathway.
Rapid angiogenic hydrogel nanofiber scaffold promotes random flap regeneration and modulates inflammation.
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p.
Luteolin modulates liver macrophage subtype polarization and play protective role in sepsis induced acute hepatic injury.
The role of Morin in attenuating atherosclerosis via STAT1 pathway inhibition.
Adhesion-Assisted Antioxidant-Engineered Mesenchymal Stromal Cells for Enhanced Cardiac Repair in Myocardial Infarction.
Adverse Outcome Pathway-Based Strategies to Mitigate Ag(2)Se Quantum Dot-Induced Neurotoxicity.
Platelet Membrane and miR-181a-5p Doubly Optimized Nanovesicles Enhance Cardiac Repair Post-Myocardial Infarction through Macrophage Polarization.
Immune-mediated regeneration of cell-free vascular grafts in an ovine model.
Biomimetic gold nano-modulator for deep-tumor NIR-II photothermal immunotherapy via gaseous microenvironment remodeling strategy.
Corilagin enhances wound healing by modulating the macrophage phenotype in diabetic mice.
Administration of Porphyromonas gingivalis in pregnant mice enhances glycolysis and histone lactylation/ADAM17 leading to cleft palate in offspring.
Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment.
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
LCN2 Regulates Microglia Polarization Through the p38MAPK-PGC-1α-PPARγ Pathway to Alleviate Traumatic Brain Injury.
Multifunctional injectable hydrogel incorporating EGCG-Cu complexes for synergistic antibacterial, immunomodulatory, and osteogenic therapy in periodontitis.
Macrophage membrane functionalized composite microspheres promote bone regeneration in periodontitis via manipulating inflammation reversing-osteogenesis coupling.
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
3D bioprinted biomimetic MOF-functionalized hydrogel scaffolds for bone regeneration: Synergistic osteogenesis and osteoimmunomodulation.
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment.
Green synthesis of silver nanoparticles using Fructus Aurantii-loaded Citrus pectin hydrogel for accelerated healing of MRSA-infected diabetic wounds.
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation.
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Myeloid-specific deficiency of group VIA calcium-independent phospholipase A2 preconditions myeloid cells for injury resolution after acetaminophen exposure.
TREM2 activation reduces white matter injury via PI3K/Akt/GSK-3β signalling after intracerebral haemorrhage.
Gallic acid promotes M2 macrophage polarization through mitochondrial oxidative phosphorylation in periodontitis.
IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway.
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Enhanced engraftment and immunomodulatory effects of integrin alpha-2-overexpressing mesenchymal stromal cells in lipopolysaccharide-induced acute lung injury.
miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.
SPI1 upregulated LILRB2 to enhance the immunosuppressive phenotype of LPS-tolerant macrophages by inhibiting TLR8-mediated MyD88/NF-κB signaling.
Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway.
Polyphosphate- and Antioxidant Peptide-Based Coacervate Delivers miRNA.
Betulinic acid enhances autopahgy to promote microglial M2 polarization and alleviate inflammation via AMPK-HDAC5-KLF2 signaling pathways in spinal cord injury.
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
PDGFC secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and immunosuppression in lung adenocarcinoma.
Platelet Membrane-Coated Drug-Loaded Nanoparticles for Dual-Modal Imaging and Photodynamic Therapy in Triple-Negative Breast Cancer.
Fate reversal: Exosome-driven macrophage rejuvenation and bacterial-responsive drug release for infection immunotherapy in diabetes.
Secretome enriched with small extracellular vesicles derived from human gingiva-derived mesenchymal stem cells enhances rat tongue muscle regeneration.
M2 macrophage derived exosomal miR-20a-5p ameliorates trophoblast pyroptosis and placental injuries in obstetric antiphospholipid syndrome via the TXNIP/NLRP3 axis.
GDF11 Regulates M1 and M2 Polarization of BV2 Microglial Cells via p38 MAPK Signaling Pathway.
Cannabinoid Receptor-2 Alleviates Sepsis-Induced Neuroinflammation by Modulating Microglia M1/M2 Subset Polarization Through Inhibiting Nogo-B Expression.
Oncostatin-M functionalized cryogel microspheres for promoting diabetic bone defects regeneration.
Human dental follicle cell-derived conditioned media enhance periodontal regeneration by regulating the osteogenic differentiation and inflammation of periodontal ligament stem cells and macrophage polarization.
Hyaluronic acid methacryloyl hydrogel with sustained IL-10 release promotes macrophage M2 polarization and motor function after spinal cord injury.
A glycopeptide-based pH-responsive hydrogel promotes diabetic wound healing via antimicrobial and remodeling microenvironment.
Notch signaling pathway regulates the progression of fetal growth restriction through mediating immune dysfunction.
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
The mechanism of action of GLUT1 in promoting NETs-mediated impairment of macrophage phenotypic switching based on macrophage-fibroblast interplay.
M2 Macrophage-Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1(hi) Neutrophils to Enhance Inflamed Bone Regeneration.
Evidence for imbalanced polarization of caruncle macrophages in retained placenta of dairy cows.
DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy.
M2 macrophage-secreted KYNU promotes stemness remodeling and malignant behavior in endometrial cancer via the SOD2-mtROS-ERO1α-UPR(ER) axis.
Icariin delivery system based on covalent organic framework materials: dual effects of immune modulation and osteogenesis promotion.
A cell-free SHED lysate-hydrogel system for oral ulcer healing with anti-inflammatory and pro-angiogenic effects.
Wenxia Changfu formula inhibits Lewis lung cancer metastasis by reprogramming tumor-associated macrophages through the PPAR-γ/CD36 pathway.
Targeted Inhibition of Aldose Reductase by Isoliquiritigenin Suppresses Fatty Acid Synthesis to Inhibit Macrophage M2 Polarization and Alleviate Pulmonary Fibrosis.
Biomimetic Nanoparticles Simultaneously Targeting Modulation of Lipid Metabolism and Phenotype of Macrophages for Programmed Atherosclerosis Management.
Cellular Landscape of Synovial Chondromatosis Synovium Revealed by Single-Cell RNA Sequencing.
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Double-Layer Nucleoside-Microneedles Co-Delivering Dexamethasone Vesicles and Adenosine Overcome Pseudomembrane Barriers for the Treatment of Oral Ulcer.
Integrative proteomics and metabolomics analyses reveals the regulation of autophagy and ferroptosis by RAB10 through Slc37a2/mTOR pathway in breast cancer.
Microglial exosome TREM2 ameliorates ferroptosis and neuroinflammation in alzheimer's disease by activating the Wnt/β-catenin signaling.
SESN3 restrains the progress of idiopathic pulmonary fibrosis by targeting the activity of FOSL2.
A Zinc-Citrate Metal-Organic Framework-Based Adaptable Hydrogen Sulfide Delivery System for Regulating Neuroregeneration Microenvironment in Spinal Cord Injury.
Nuclear receptor subfamily 1 group D member 2 induces chemoresistance in ovarian cancer by regulating ferroptosis and immune infiltration.
Tumor-associated macrophages derived exosomal circPLK1 promotes resistance to EGFR inhibitor osimertinib in non-small cell lung cancer.
Highly BBB-permeable nanomedicine reverses neuroapoptosis and neuroinflammation to treat Alzheimer's disease.
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
Protective role of Yougui Yin in experimental knee osteoarthritis: From the perspective of macrophage polarization.
An Optimized Decellularized Extracellular Matrix from Dental Pulp Stem Cell Sheets Promotes Axonal Regeneration by Multiple Modes in Spinal Cord Injury Rats.
Inhibition of PKM2 by shikonin impedes TGF-β1 expression by repressing histone lactylation to alleviate renal fibrosis.
Ginsenoside RK3 inhibits glioblastoma by modulating macrophage M2 polarization via the PPARG/CCL2 axis.
The Anti-Inflammatory Effects of Formononetin, an Active Constituent of Pueraria montana Var. Lobata, via Modulation of Macrophage Autophagy and Polarization.
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.
STEAP3-SLC39A8-mediated microglia ferroptosis involved in neurotoxicity in rats after exposure to lead and cadmium combined.
ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation.
Extracellular Matrix-Mimicking Hydrogel with Angiogenic and Immunomodulatory Properties Accelerates Healing of Diabetic Wounds by Promoting Autophagy.
Nitric Oxide-Releasing Mesoporous Hollow Cerium Oxide Nanozyme-Based Hydrogel Synergizes with Neural Stem Cell for Spinal Cord Injury Repair.
BMP6, a potential biomarker of inflammatory fibrosis and promising protective factor for dilated cardiomyopathy.
ALKBH5 alleviates lower extremity arteriosclerosis by regulating ITGB1 demethylation and influencing macrophage polarization.
Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice.
YTHDF1-mediated m6A modification of GBP4 promotes M1 macrophage polarization in acute lung injury.
IFN-τ Maintains Immune Tolerance by Promoting M2 Macrophage Polarization via Modulation of Bta-miR-30b-5p in Early Uterine Pregnancy in Dairy Cows.
N 6-Methyladenosine Demethylase FTO Controls Macrophage Homeostasis in Diabetic Vasculopathy.
Macrophage metabolic reprogramming ameliorates diabetes-induced microvascular dysfunction.
The chemokine CX3CL1 promotes intraperitoneal tumour growth despite enhanced T-cell recruitment in ovarian cancer.
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling.
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection.
Dual-sided centripetal microgrooved poly (D,L-lactide-co-caprolactone) disk encased in immune-regulating hydrogels for enhanced bone regeneration.
Hyaluronidase-responsive hydrogel loaded with magnetic nanoparticles combined with external magnetic stimulation for spinal cord injury repair.
Gelatin methacryloyl hydrogel encapsulating molybdenum-inspired macrophage-derived exosomes accelerates wound healing via immune regulation and angiogenesis.
The promoting effect of Balanus albicostatus cement protein 19k (Balcp19k) on wound healing by regulating fibroblast migration and relieving early-stage inflammation responses.
Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain.
Effect of 3D-Printed Polycaprolactone Scaffold With Powdery/Smooth Micromorphology on Local Immune Environments.
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis.
Understanding the relationship between silicone implants, tumor antigens, and breast cancer risk: An immunological study in rats.
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway.
Exosomes from adipose-derived stem cells accelerate wound healing by increasing the release of IL-33 from macrophages.
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress.
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Peptide amphiphiles alleviate myocardial endoplasmic reticulum stress to enhance cardiomyocyte-macrophage communication and promote macrophage M2 polarization.
Bulk and Single-cell transcriptomic profiling identifies C1QA as an Immune-Associated hub genes in graves' ophthalmopathy.
P4HB regulates tumor-associated macrophage polarization and chemotaxis by enhancing IL-6 cytokine secretion in glioblastoma.
SPP1-mediated crosstalk between macrophage and fibroblasts promotes benign airway stenosis.
Indirubin regulates M1/M2 polarization and inhibits ferroptosis in dextran sulfate sodium induced colitis and in cultured THP-1 cells.
PFKFB3-Inhibitor 3PO-Mediated Glycolytic Reprogramming Promotes Inflammatory Dental Pulp Repair: An In Vitro and In Vivo Study.
Exosomal miR-216a-5p targeting TLR-4 alleviates liver ischemia-reperfusion injury by regulating M2 macrophage polarization and neutrophil inflammation.
Lactobacillus extracellular vesicle-driven oxygen-releasing photothermal hydrogel reprograms macrophages and promotes angiogenesis to accelerate diabetic wound healing.
Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization.
Synthesis of novel pyrazole derivatives and neuroprotective effect investigation.
Functionalized hydrocaffeic acid-chitosan/EGTA hydrogel rescues mitochondrial dysfunction for immunomodulation and joint repair in rheumatoid arthritis.
4'-hydroxychalcone nanofiber hydrogel dressing promotes diabetic chronic wound healing by regulating macrophage polarization via the TLR/IL-17/TNF signaling pathway.
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Isoliquiritigenin micellar microneedle for pH monitoring and diabetic wound healing.
ACOD1/Itaconate regulates trophoblast function through the PI3K/Akt/FOLR1 axis to participate in the pathogenesis of recurrent spontaneous abortion.
Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
A study on the establishment of a traumatic brain injury model of tree shrews and the observation of neuroinflammatory responses.
Z-Ligustilide's antidepressant effects in adolescent depression involve the PTEN-induced putative kinase 1 (PINK1) - protein kinase A (PKA)- Na(+)/Ca(2+) exchanger (NCLX) pathway, facilitating mitochondrial endosymbiosis and promoting mitophagy in microglia.
Viscoelastic Hydrogel with Mechanomodulatory Tension Shielding and Time-Dependent Immunomodulatory Effects for Scarless Healing.
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
EGCG-Loaded Zinc Ion-Cross-Linked Injectable Sodium Alginate Hydrogel for Extraction Socket Healing.
Autophagy-dependent secretion of ENO1 mediates chemoresistance of glioblastoma and tumor microenvironment remodeling.
The Role of Chaf1b in Maintaining Glioma Stem Cell Stemness and Regulating Microglial Polarization.
CD146(+) CAFs mediate immunosuppression in gastric cancer via COL4A1: potential therapeutic targets.
Human urine-derived stem cells alleviate psoriasis by suppressing JAK2/STAT3 pathway-mediated macrophage polarization.
Identification and targeting oxidative phosphorylation/glycolysis to overcome anti-CSF-1R therapy resistance in glioblastoma.
tsRNA-10105-enriched migrasomes mediate hepatocellular carcinoma immunosuppressive microenvironment by inducing M2 Macrophage polarization.
Scutellarin Modulates Astrocyte-Microglia-Neuron Crosstalk to Mitigate Neuroinflammation and Apoptosis in Cerebral Ischemia.
Pathology-inspired collagen-binding thermosensitive micelle drops enable prolonged and efficient treatment of fungal keratitis.
Quorum Sensing Molecule Autoinducer-2 Promotes Macrophage Classical Polarization and Exacerbates Periodontal Inflammation Via Nf-Κb Signalling.
Irisin Alleviates Autoimmune Uveitis Through Promoting Retinal Microglial M1 to M2 Phenotypic Polarization Mediated by HIF-1α Pathway.
More severe vascular remodeling in deep brain regions caused by hemodynamic differences is a potential mechanism of hypertensive cerebral small vessel disease.
Rescuing inflammatory microenvironment induced senescence via MgO immune mediated asymmetric short fibers for accelerating diabetic wound repair.
Hyaluronic acid-anchored nanoparticles co-delivering emodin and siRNA confers protection against rheumatoid arthritis via macrophage polarization.
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
A novel triazole derivative ameliorates ulcerative colitis by targeting PPAR gamma.
Immunoregulatory function and anticancer effects of Polygonatum sibiricum polysaccharides against hepatic carcinoma via macrophage phenotype modulation.
IGF2BP1 exacerbates neuroinflammation and cerebral ischemia/reperfusion injury by regulating neuronal ferroptosis and microglial polarization.
TSPO participates in the pathogenesis of diabetic periodontitis related to mitophagy.
Gut Microbiota-Derived Acetate Ameliorates Endometriosis via JAK1/STAT3-Mediated M1 Macrophage Polarisation.
Modified Fish-Skin-Collagen-Based Hydrogels with Antioxidant and Antibacterial Functions for Diabetic Wound Healing.
MDL800, a SIRT6 activator, mitigates neuroinflammation-induced retinal damage by modulating microglial M1/M2 polarization in experimental glaucoma.
Intravenous administration of mesenchymal stem cell-derived exosomes mitigates traumatic brain injury by inhibiting neutrophil extracellular trap formation via miR-26a-5p.
COG1410 Alleviated Chronic Sleep Deprivation-Induced Memory Loss by Regulating Microglial Phagocytosis and Inhibiting Hippocampal Inflammation.
Dihydroartemisinin restrains angiogenesis through the TNF-α pathway to enhance the efficacy of anti-PD-1 immunotherapy in breast cancer.
Kurarinone protects against renal injury and fibrosis after unilateral ureteral obstruction through enhancement of the Nrf-2 signaling pathway.
Activation of M1 macrophages promotes diabetic kidney disease by modulating glycolysis via HIF-1α-HK2 signaling pathway.
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
CAF-derived exosomes drive the FGF4/SHH feedback loop by encapsulating GREM1 in non-small cell lung cancer.
Ultrasound-triggered targeted delivery of engineered ADSCs-derived exosomes with high SDF-1α levels to promote cardiac repair following myocardial infarction.
RBM15 enhances paclitaxel resistance in triple-negative breast cancer by targeting m(6)A methylation of TNFSF9 and inducing polarization of tumor-associated macrophages to M2 phenotype.
Functional anti-inflammatory mesoporous silica nanoplatform for Synergistic and Targeted abdominal aortic aneurysm treatment.
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Galvanic Cell Bipolar Microneedle Patches for Reversing Photoaging Wrinkles.
An injectable and adaptable system for the sustained release of hydrogen sulfide for targeted diabetic wound therapy by improving the microenvironment of inflammation regulation and angiogenesis.
Activation of aryl hydrocarbon receptor attenuates intestinal inflammation by enhancing IRF4-mediated macrophage M2 polarization.
Glioblastoma- derived exosomes (GBM-Exo) regulate microglial M2 polarization via the RAC1/AKT/NRF2 pathway.
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.
Prevascularized Hydrogel Enhancing Innervation and Repair of Full-Thickness Volumetric Muscle Loss in Abdominal Wall Defects.
The Phase-Transited Lysozyme Coating Modified Small Intestinal Submucosa Membrane Loaded with Calcium and Zinc Ions for Enhanced Bone Regeneration.
Mannose-Glycated Metal-Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy.
CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-Associated Macrophages.
Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.
A poly(ether-ketone-ketone) composite scaffold simulating the immune-osteogenic cascade for in situ bone regeneration.
Multi-Omics Analysis of the Immune Effect of the Engineered Exosome Drug Delivery System in Inducing Macrophage Apoptosis.
Platycodon grandiflorum exosome-like nanoparticles: the material basis of fresh platycodon grandiflorum optimality and its mechanism in regulating acute lung injury.
Silybin attenuates microglia-mediated neuroinflammation via inhibition of STING in experimental subarachnoid hemorrhage.
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
TIPE3 promotes drug resistance in colorectal cancer by enhancing autophagy via the USP19/Beclin1 pathway.
Formononetin ameliorates depression-like behaviors through rebalancing microglia M1/M2 polarization and inhibiting NLRP3 inflammasome: involvement of activating PPARα-mediated autophagy.
Lactiplantibacillus plantarum -derived extracellular vesicles alleviate acute lung injury by inhibiting ferroptosis of macrophages.
Facile Nanocomposite Hydrogel Scaffold with Sustained Drug Release and Osteo-Immunomodulatory Effects to Enhance Bone Regeneration.
The E3 ligase c-Cbl modulates microglial phenotypes and contributes to Parkinson's disease pathology.
Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8(+)T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice.
Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity.
pH-responsive and self-adaptive injectable sodium alginate/carboxymethyl chitosan hydrogel accelerates infected wound healing by bacteriostasis and immunomodulation.
Inflammatory Microenvironment-Modulated Conductive Hydrogel Promotes Vascularized Bone Regeneration in Infected Bone Defects.
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
3D mesenchymal stem cell exosome-functionalized hydrogels for corneal wound healing.
A novel TLR4 accessory molecule drives hepatic oncogenesis through tumor-associated macrophages.
Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion.
Bifunctional TRPV1 Targeted Magnetothermal Switch to Attenuate Osteoarthritis Progression.
SNORA5A regulates tumor-associated macrophage M1/M2 phenotypes via TRAF3IP3 in breast cancer.
Hollow Bismuth Nanoparticle-Loaded Gelatin Hydrogel Regulates M2 Polarization of Macrophages to Promote Infected Wound Healing.
The role and mechanism of macrophage autophagy in the experimental model of chronic obstructive pulmonary disease.
Transglutaminase 2 inhibition ameliorates cardiac fibrosis in myocardial infarction by inducing M2 macrophage polarization in vitro and in vivo.
Conditioned Medium Derived From Human Dental Follicle Mesenchymal Stem Cells Alleviates Macrophage Proinflammatory Responses Through MAPK-ERK-EGR1 Axis.
Optogenetic Stimulation of the Cardiac Vagus Nerve to Promote Heart Regenerative Repair after Myocardial Infarction.
Breast cancer-derived CAV1 promotes lung metastasis by regulating integrin α6β4 and the recruitment and polarization of tumor-associated neutrophils.
Nerve growth factor promote VCAM-1-dependent monocyte adhesion and M2 polarization in osteosarcoma microenvironment: Implications for larotrectinib therapy.
Magnesium Ion-Doped Mesoporous Bioactive Glasses Loaded with Gallic Acid Against Myocardial Ischemia/Reperfusion Injury by Affecting the Biological Functions of Multiple Cells.
Sphingosine Kinase 1 Aggravates Liver Fibrosis by Mediating Macrophage Recruitment and Polarization.
(+)-Borneol inhibits neuroinflammation and M1 phenotype polarization of microglia in epileptogenesis through the TLR4-NFκB signaling pathway.
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.
Pretreated MSCs with IronQ Transplantation Attenuate Microglia Neuroinflammation via the cGAS-STING Signaling Pathway.
The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression.
Songorine modulates macrophage polarization and metabolic reprogramming to alleviate inflammation in osteoarthritis.
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
In situ MgO nanoparticle-doped Janus electrospun dressing against bacterial invasion and immune imbalance for irregular wound healing.
Spatiotemporal evolutionary process of osteosarcoma immune microenvironment remodeling and C1QBP-driven drug resistance deciphered through single-cell multi-dimensional analysis.
Tangeretin alleviates inflammation and oxidative response induced by spinal cord injury by activating the Sesn2/Keap1/Nrf2 pathway.
Targeted delivery of berberine using bionic nanomaterials for Atherosclerosis therapy.
5-aminolevulinic acid photodynamic therapy for chronic wound infection in rats with diabetes.
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Tumoral EIF4EBP1 regulates the crosstalk between tumor-associated macrophages and tumor cells in MRTK.
Nobiletin alleviates macrophage M2 polarization by activating AMPK-mTOR-mediated autophagy in pulmonary fibrosis mice.
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis.
Anti-colorectal cancer activity of mannatide from spent brewer's yeast by regulating immune cells and immune function in the tumor microenvironment.
Hypoxic microenvironment promotes diabetic wound healing by polarizing macrophages to the M2 phenotype in vivo.
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis.
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease.
Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma.
Novel Collagen Analogs with Multicopy Mucin-Type Sequences for Multifunctional Enhancement Properties Using SUMO Fusion Tags.
Bioactivity-Oriented Separation of "Pepper Alkaloids" from Piper sintenense Hatusima with Potential Antigouty Arthritis Activity.
Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment.
A hydrogen generator composed of poly (lactic-co-glycolic acid) nanofibre membrane loaded iron nanoparticles for infectious diabetic wound repair.
Chronic exposure to polystyrene microplastics induced LHR reduction and decreased testosterone levels through NF-κB pathway.
M2 Macrophage Polarization and Tissue Remodeling in Autologous Fat Grafting for Diabetic Skin Defects.
Synergistic rheumatoid arthritis therapy by interrupting the detrimental feedback loop to orchestrate hypoxia M1 macrophage polarization using an enzyme-catalyzed nanoplatform.
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
A polysaccharide from Periplaneta americana promotes macrophage M2 polarization, exhibiting anti-inflammatory and wound-healing activities.
Esculetin rebalances M1/M2 macrophage polarization to treat sepsis-induced acute lung injury through regulating metabolic reprogramming.
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.
Dual-targeted halofuginone hydrobromide nanocomplexes for promotion of macrophage repolarization and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes in adjuvant-induced arthritis in rats.
Leukocyte Platelet-Rich Plasma-Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization.
An Engineered Hierarchical Hydrogel with Immune Responsiveness and Targeted Mitochondrial Transfer to Augmented Bone Regeneration.
Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway.
MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition.
Target-Engineered Liposomes Decorated with Nanozymes Alleviate Liver Fibrosis by Remodeling the Liver Microenvironment.
Establishment of an Immortalized Porcine Alveolar Macrophage Cell Line That Supports Efficient Replication of Porcine Reproductive and Respiratory Syndrome Viruses.
Adipose stem cell exosomes, stimulated by pro-inflammatory factors, enhance immune evasion in triple-negative breast cancer by modulating the HDAC6/STAT3/PD-L1 pathway through the transporter UCHL1.
Macrophage erythropoietin signaling promotes macrophage-myofibroblast transformation and fibroblast-myofibroblast differentiation.
Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing.
Astragaloside IV promotes cerebral tissue restoration through activating AMPK- mediated microglia polarization in ischemic stroke rats.
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Exosome-derived circ-001422 promotes tumor-associated macrophage M2 polarization to accelerate the progression of glioma.
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Gastrodin Regulates PI3K/AKT-Sirt3 Signaling Pathway and Proinflammatory Mediators in Activated Microglia.
Versatile dopamine-functionalized hyaluronic acid-recombinant human collagen hydrogel promoting diabetic wound healing via inflammation control and vascularization tissue regeneration.
Highly active probiotic hydrogels matrixed on bacterial EPS accelerate wound healing via maintaining stable skin microbiota and reducing inflammation.
Analysis of the effects of M2 macrophage-derived PDE4C on the prognosis, metastasis and immunotherapy benefit of osteosarcoma.
MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.
Combining antibiotic-loaded bone cement-based free vastus lateralis muscle-sparing flap with split-thickness skin grafts: A reliable strategy for reconstructing diabetic foot ulcers at non-weight-bearing areas.
Ultrasmall Nanoparticles Regulate Immune Microenvironment by Activating IL-33/ST2 to Alleviate Renal Ischemia-Reperfusion Injury.
Turmeric-Derived Nanoparticles Functionalized Aerogel Regulates Multicellular Networks to Promote Diabetic Wound Healing.
Modulation of Cerebrospinal Fluid Dysregulation via a SPAK and OSR1 Targeted Framework Nucleic Acid in Hydrocephalus.
Macrophage-derived ectosomal miR-350-3p promotes osteoarthritis progression through downregulating chondrocyte H3K36 methyltransferase NSD1.
Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma.
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
The novel vaccines targeting interleukin-1 receptor type I.
Photothermal and Photocatalytic Glycol Chitosan and Polydopamine-Grafted Oxygen Vacancy Bismuth Oxyiodide (BiO(1-x) I) Nanoparticles for the Diagnosis and Targeted Therapy of Diabetic Wounds.
Arctium lappa L. polysaccharides enhanced the therapeutic effects of nasal ectomesenchymal stem cells against liver fibrosis by inhibiting the Wnt/β-catenin pathway.
A multifunctional composite nanoparticle with antibacterial activities, anti-inflammatory, and angiogenesis for diabetic wound healing.
Hydrogen exerts neuroprotective effects after subarachnoid hemorrhage by attenuating neuronal ferroptosis and inhibiting neuroinflammation.
A Biomimetic Se-nHA/PC Composite Microsphere with Synergistic Immunomodulatory and Osteogenic Ability to Activate Bone Regeneration in Periodontitis.
Biomimetic "Gemini nanoimmunoregulators" orchestrated for boosted photoimmunotherapy by spatiotemporally modulating PD-L1 and tumor-associated macrophages.
Wireless Electric Cues Mediate Autologous DPSC-Loaded Conductive Hydrogel Microspheres to Engineer the Immuno-Angiogenic Niche for Homologous Maxillofacial Bone Regeneration.
Lentinan inhibits cell invasion via M2 polarization of tumor-associated macrophages and Wnt/β-catenin signaling in non-small cell lung cancer.
Investigation of Expanded Human Adipose-derived Stem Cell Dosage and Timing for Improved Defecation Function.
Antibacterial, ROS scavenging and angiogenesis promotingϵ-Polylysine/gelatin based hydrogel containing CTLP to regulate macrophages for pressure ulcer healing.
Tibial cortex transverse transport promotes ischemic diabetic foot ulcer healing via enhanced angiogenesis and inflammation modulation in a novel rat model.
PGRN inhibits CD8(+)T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM.
Tryptanthrin promotes pressure ulcers healing in mice by inhibiting macrophage-mediated inflammation via cGAS/STING pathways.
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Anti-inflammatory and anti-oxidative electrospun nanofiber membrane promotes diabetic wound healing via macrophage modulation.
Lipolysis inhibition improves the survival of fat grafts through ameliorating lipotoxicity and inflammation.
Wuling capsule modulates macrophage polarization by inhibiting the TLR4-NF-κB signaling pathway to relieve liver fibrosis.
Jiawei Taohe Chengqi decoction inhibition of the notch signal pathway affects macrophage reprogramming to inhibit HSCs activation for the treatment of hepatic fibrosis.
Establishment of an in situ model to explore the tumor immune microenvironment in head and neck squamous cell carcinoma.
Collagen sponge scaffolds loaded with Trichostatin A pretreated BMSCs-derived exosomes regulate macrophage polarization to promote skin wound healing.
Dual-crosslinking gelatin-hyaluronic acid methacrylate based biomimetic PDAC desmoplastic niche enhances tumor-associated macrophages recruitment and M2-like polarization.
GO-PEG Represses the Progression of Liver Inflammation via Regulating the M1/M2 Polarization of Kupffer Cells.
Relieving Macrophage Dysfunction by Inhibiting SREBP2 Activity: A Hypoxic Mesenchymal Stem Cells-Derived Exosomes Loaded Multifunctional Hydrogel for Accelerated Diabetic Wound Healing.
Decreased Proteasomal Function Exacerbates Endoplasmic Reticulum Stress-Induced Chronic Inflammation in Obese Adipose Tissue.
Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway.
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
A Graphene Composite Film Based Wearable Far-Infrared Therapy Apparatus (GRAFT) for Effective Prevention of Postoperative Peritoneal Adhesion.
NIR triggered polydopamine coated cerium dioxide nanozyme for ameliorating acute lung injury via enhanced ROS scavenging.
Nicotine promotes Staphylococcus aureus-induced osteomyelitis by activating the Nrf2/Slc7a11 signaling axis.
The STAT3 inhibitor B9 alleviates lipopolysaccharide-induced acute lung injury through its anti-inflammatory effects.
Oral microsphere formulation of M2 macrophage-mimetic Janus nanomotor for targeted therapy of ulcerative colitis.
Hyperbaric Oxygen Therapy as a Novel Approach to Modulating Macrophage Polarization for the Treatment of Glioblastoma.
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Sr-Incorporated Bioactive Glass Remodels the Immunological Microenvironment by Enhancing the Mitochondrial Function of Macrophage via the PI3K/AKT/mTOR Signaling Pathway.
tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer.
Perinatal loss of galactosylceramidase in both oligodendrocytes and microglia is crucial for the pathogenesis of Krabbe disease in mice.
Multifunctional Microneedle Patch Based on Metal-Phenolic Network with Photothermal Antimicrobial, ROS Scavenging, Immunomodulatory, and Angiogenesis for Programmed Treatment of Diabetic Wound Healing.
HMGB1/TREM2 positive feedback loop drives the development of radioresistance and immune escape of glioblastoma by regulating TLR4/Akt signaling.
Icariside II modulates pulmonary fibrosis via PI3K/Akt/β-catenin pathway inhibition of M2 macrophage program.
Engineered Mesenchymal Stromal Cell Exosomes-Loaded Microneedles Improve Corneal Healing after Chemical Injury.
Shape-fixing hydrogel promotes scarless healing of wounds under tension.
MSCs-exosomes can promote macrophage M2 polarization via exosomal miR-21-5p through Mesenteric injection: a promising way to attenuate murine colitis.
LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis.
Gab2 promotes the growth of colorectal cancer by regulating the M2 polarization of tumor‑associated macrophages.
Ultrasound-triggered biomimetic ultrashort peptide nanofiber hydrogels promote bone regeneration by modulating macrophage and the osteogenic immune microenvironment.
Sprayable chitosan nanogel with nitric oxide to accelerate diabetic wound healing through bacteria inhibition, biofilm eradication and macrophage polarization.
Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.
Hinokitiol as a modulator of TLR4 signaling and apoptotic pathways in atopic dermatitis.
NIR-Actuated Targeted Janus Nanomotors Remodel Immunosuppressive Tumor Microenvironment for Augmented Cancer Immunotherapy.
Macelignan prevents colorectal cancer metastasis by inhibiting M2 macrophage polarization.
Urethral Microenvironment Adapted Sodium Alginate/Gelatin/Reduced Graphene Oxide Biomimetic Patch Improves Scarless Urethral Regeneration.
Carveol alleviates osteoarthritis progression by acting on synovial macrophage polarization transformation: An in vitro and in vivo study.
Discovery of β-sitosterol's effects on molecular changes in rat diabetic wounds and its impact on angiogenesis and macrophages.
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.
Targeted mRNA Nanoparticles Ameliorate Blood-Brain Barrier Disruption Postischemic Stroke by Modulating Microglia Polarization.
Rutin prevents pyroptosis and M1 microglia via Nrf2/Mac-1/caspase-1-mediated inflammasome axis to improve POCD.
Synergistic Amelioration of Osseointegration and Osteoimmunomodulation with a Microarc Oxidation-Treated Three-Dimensionally Printed Ti-24Nb-4Zr-8Sn Scaffold via Surface Activity and Low Elastic Modulus.
High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cells.
Metformin protects ovarian granulosa cells in chemotherapy-induced premature ovarian failure mice through AMPK/PPAR-γ/SIRT1 pathway.
Salvianolic Acid B Alleviates Liver Injury by Regulating Lactate-Mediated Histone Lactylation in Macrophages.
TREM2 regulates BV2 microglia activation and influences corticosterone-induced neuroinflammation in depressive disorders.
Reprogramming tumor-associated macrophages by a dually targeted milk exosome system as a potent monotherapy for cancer.
Efficient pulmonary fibrosis therapy via regulating macrophage polarization using respirable cryptotanshinone-loaded liposomal microparticles.
Reprogramming macrophages via immune cell mobilized hydrogel microspheres for osteoarthritis treatments.
Human umbilical cord derived mesenchymal stem cells overexpressing HO-1 attenuate neural injury and enhance functional recovery by inhibiting inflammation in stroke mice.
Alleviating 3-MCPD-induced male reproductive toxicity: Mechanistic insights and resveratrol intervention.
MMP14(high) macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis.
Photobiomodulation therapy alleviates repeated closed head injury-induced anxiety-like behaviors.
Troxerutin dampened hypothalamic neuroinflammation via microglial IL-22/IL-22R1/IRF3 activation in dihydrotestosterone-induced polycystic ovary syndrome rats.
Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
Fabrication of levofloxacin-loaded porcine acellular dermal matrix hydrogel and functional assessment in urinary tract infection.
Protective effect of Tetrandrine on optic nerve by inhibiting glial activation through NF-κB pathway.
Periodontitis aggravates COPD through the activation of γδ T cell and M2 macrophage.
TRIM65 knockout inhibits the development of HCC by polarization tumor-associated macrophages towards M1 phenotype via JAK1/STAT1 signaling pathway.
Moluodan promotes DSS-induced intestinal inflammation involving the reprogram of macrophage function and polarization.
Bromodomain containing 4 inhibition combats gastric precancerous lesions via modulating macrophage polarization.
An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain.
Histone Lactylation-Driven GPD2 Mediates M2 Macrophage Polarization to Promote Malignant Transformation of Cervical Cancer Progression.
Microenvironment-responsive nano-bioconjugated vesicles for the multi-pronged treatment of liver fibrosis.
Bioactive sucralfate-based microneedles promote wound healing through reprogramming macrophages and protecting endogenous growth factors.
A Novel Compound Ligusticum Cycloprolactam Alleviates Neuroinflammation After Ischemic Stroke via the FPR1/NLRP3 Signaling Axis.
Single-cell RNA sequencing reveals the intercellular crosstalk and the regulatory landscape of stromal cells during the whole life of the mouse ovary.
MSCs-derived ECM functionalized hydrogel regulates macrophage reprogramming for osteoarthritis treatment by improving mitochondrial function and energy metabolism.
Licochalcone A loaded multifunctional chitosan hyaluronic acid hydrogel with antibacterial and inflammatory regulating effects to promote wound healing.
Multifunctional carboxymethyl chitosan/oxidized carboxymethyl cellulose hydrogel loaded with ginsenoside Rg1 and polydopamine nanoparticles for infected diabetic wound healing.
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway.
Spatial dimension cues derived from fibrous scaffolds trigger mechanical activation to potentiate the paracrine and regenerative functions of MSCs via the FAK-PI3K/AKT axis.
Controlled Release of Ceria and Ferric Oxide Nanoparticles via Collagen Hydrogel for Enhanced Osteoarthritis Therapy.
Hierarchical Integration of Curcumin-Loaded CaCO(3) Nanoparticles and Black Phosphorus Nanosheets in Core/Shell Nanofiber for Cranial Defect Repair.
A Core-Brush Nanoplatform with Enhanced Lubrication and Anti-Inflammatory Properties for Osteoarthritis Treatment.
Adropin regulates macrophage phenotype via PPARγ signalling: A preliminary study of adropin and Crohn's disease.
Treadmill exercise improves cerebral ischemia injury by regulating microglia polarization via downregulation of MMP12.
Kaempferol improves depression-like behaviors through shifting microglia polarization and suppressing NLRP3 via tilting the balance of PPARγ and STAT1 signaling.
Caulerpin alleviates cyclophosphamide-induced ovarian toxicity by modulating macrophage-associated granulosa cell senescence during breast cancer chemotherapy.
FOXF2 suppressed esophageal squamous cell carcinoma by reducing M2 TAMs via modulating RNF144A-FTO axis.
HPV11 targeting KDM4A regulates the polarization of macrophage M(1) and promotes the development of nasal inverted papilloma.
Autophagy-mediated activation of the AIM2 inflammasome enhances M1 polarization of microglia and exacerbates retinal neovascularization.
DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis.
HSP110 aggravates ischemia-reperfusion injury after liver transplantation by promoting NF-κB pathway.
Dissection of triple-negative breast cancer microenvironment and identification of potential therapeutic drugs using single-cell RNA sequencing analysis.
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
rTMS applied to the PFC relieves neuropathic pain and modulates neuroinflammation in CCI rats.
Apilarnil exerts neuroprotective effects and alleviates motor dysfunction by rebalancing M1/M2 microglia polarization, regulating miR-155 and miR-124 expression in a rotenone-induced Parkinson's disease rat model.
Adipose-derived stem cell exosomes loaded with icariin attenuated M1 polarization of macrophages via inhibiting the TLR4/Myd88/NF-κB signaling pathway.
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
Peimine promotes microglial polarization to the M2 phenotype to attenuate drug-resistant epilepsy through suppressing the TLR4/NF-κB/HIF-1α signaling pathway in a rat model and in BV-2 microglia.
Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway.
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages.
Upregulation of MELK promotes chemoresistance and induces macrophage M2 polarization via CSF-1/JAK2/STAT3 pathway in gastric cancer.
Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury.
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway.
Multifunctional nanocoatings with synergistic controlled release of zinc ions and cytokines for precise modulation of vascular intimal reconstruction.
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
IRF4 induces M1 macrophage polarization and aggravates ulcerative colitis progression by the Bcl6-dependent STAT3 pathway.
Effect of Low-Intensity Pulsed Ultrasound on Macrophage Properties and Fibrosis in the Infrapatellar Fat Pad in a Carrageenan-Induced Knee Osteoarthritis Rat Model.
Ferrous/Ferric Ions Crosslinked Type II Collagen Multifunctional Hydrogel for Advanced Osteoarthritis Treatment.
Dehydroandrographolide facilitates M2 macrophage polarization by downregulating DUSP3 to inhibit sepsis-associated acute kidney injury.
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment.
Buyang Huanwu Decoction promotes neurovascular remodeling by modulating astrocyte and microglia polarization in ischemic stroke rats.
Bioactive fiber-reinforced hydrogel to tailor cell microenvironment for structural and functional regeneration of myotendinous junction.
Interleukin-1β polarization in M1 macrophage mediates myocardial fibrosis in diabetes.
Intratumor microbiome-derived butyrate promotes lung cancer metastasis.
FDA compound library screening Baicalin upregulates TREM2 for the treatment of cerebral ischemia-reperfusion injury.
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
LncRNA HCG18 loaded by polymorphonuclear neutrophil-secreted exosomes aggravates sepsis acute lung injury by regulating macrophage polarization.
Pathological BBB Crossing Melanin-Like Nanoparticles as Metal-Ion Chelators and Neuroinflammation Regulators against Alzheimer's Disease.
A Novel Poly(3-hexylthiophene) Engineered Interface for Electrochemical Monitoring of Ascorbic Acid During the Occurrence of Glutamate-Induced Brain Cytotoxic Edemas.
Pachymic Acid Prevents Hemorrhagic Shock-Induced Cardiac Injury by Suppressing M1 Macrophage Polarization and NF-[Formula: see text]B Signaling Pathway.
Heme-heme oxygenase-2 reduces the atherosclerosis by preventing inflammation.
P-Glycoprotein Exacerbates Brain Injury Following Experimental Cerebral Ischemia by Promoting Proinflammatory Microglia Activation.
Comprehensive Analysis Identified Glycosyltransferase Signature to Predict Glioma Prognosis and TAM Phenotype.
Radioimmunotherapy Targeting B7-H3 in situ glioma models enhanced antitumor efficacy by Reconstructing the tumor microenvironment.
Neural Stem Cell-Derived Exosomes Improve Neurological Function in Rats with Cerebral Ischemia-Reperfusion Injury by Regulating Microglia-Mediated Inflammatory Response.
Major vault protein regulates tumor-associated macrophage polarization through interaction with signal transducer and activator of transcription 6.
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
The immunomodulatory effect of IL-4 accelerates bone substitute material-mediated osteogenesis in aged rats via NLRP3 inflammasome inhibition.
High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization.
Sialidase facilitates Porphyromonas gingivalis immune evasion by reducing M1 polarization, antigen presentation, and phagocytosis of infected macrophages.
Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.
Thermos-responsive hydrogel system encapsulated engineered exosomes attenuate inflammation and oxidative damage in acute spinal cord injury.
Comparison of proteomic landscape of extracellular vesicles in pleural effusions isolated by three strategies.
BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.
Early depletion of M1 macrophages retards the progression of glucocorticoid-associated osteonecrosis of the femoral head.
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Intrinsic contractile dysfunction due to impaired sarcoplasmic reticulum Ca(2+) release in compensatory hypertrophied muscle fibers following synergist ablation.
Yangqing Chenfei formula alleviates crystalline silica induced pulmonary inflammation and fibrosis by suppressing macrophage polarization.
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression.
The infrapatellar fat pad contributes to spontaneous healing after complete anterior cruciate ligament injury.
The crosstalk between M1 macrophage polarization and energy metabolism disorder contributes to polystyrene nanoplastics-triggered testicular inflammation.
Targeting and repolarizing M2-like tumor-associated macrophage-mediated MR imaging and tumor immunotherapy by biomimetic nanoparticles.
Sulforaphene Inhibits Periodontitis through Regulating Macrophage Polarization via Upregulating Dendritic Cell Immunoreceptor.
Oroxylin a promoted apoptotic extracellular vesicles transfer of glycolytic kinases to remodel immune microenvironment in hepatocellular carcinoma model.
ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis.
Local administration of liposomal-based Plekhf1 gene therapy attenuates pulmonary fibrosis by modulating macrophage polarization.
Thermal/ultrasound-triggered release of liposomes loaded with Ganoderma applanatum polysaccharide from microbubbles for enhanced tumour ablation.
Localized delivery of anti-inflammatory agents using extracellular matrix-nanostructured lipid carriers hydrogel promotes cardiac repair post-myocardial infarction.
Dipeptidyl peptidase 4 inhibitor reduces tumor-associated macrophages and enhances anti-PD-L1-mediated tumor suppression in non-small cell lung cancer.
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
In vitro acne disease model from inertial focusing effect for studying the interactions between sebocyte glands and macrophages.
Koumine ameliorates neuroinflammation by regulating microglia polarization via activation of Nrf2/HO-1 pathway.
Electro-nape-acupuncture regulates the differentiation of microglia through PD-1/PD-L1 reducing secondary brain injury in acute phase intracerebral hemorrhage rats.
Roflumilast attenuates neuroinflammation post retinal ischemia/reperfusion injury by regulating microglia phenotype via the Nrf2/STING/NF-κB pathway.
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Silk Acid as an Implantable Biomaterial for Tissue Regeneration.
Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury.
SCH 644343 alleviates ischemic stroke-induced neuroinflammation by promoting microglial polarization via the IL-4/SREBP-1 signaling pathway.
Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization.
Four-dimensional hydrogel dressing adaptable to the urethral microenvironment for scarless urethral reconstruction.
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6.
TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling.
Silk Fibroin and Sericin Differentially Potentiate the Paracrine and Regenerative Functions of Stem Cells Through Multiomics Analysis.
miR-26a-5p alleviates CFA-induced chronic inflammatory hyperalgesia through Wnt5a/CaMKII/NFAT signaling in mice.
Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects.
Biomimetic oxygen-boosted hybrid membrane nanovesicles as the treatment strategy for ischemic stroke with the concept of the neurovascular unit.
Methionine enkephalin suppresses lung cancer metastasis by regulating the polarization of tumor-associated macrophages and the distribution of myeloid-derived suppressor cells in the tumor microenvironment and inhibiting epithelial-mesenchymal transition.
Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis.
Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma.
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
A smart pathogen detector engineered from intracellular hydrogelation of DNA-decorated macrophages.
Loss of AKAP12 aggravates rheumatoid arthritis-like symptoms and cardiac damage in collagen-induced arthritis mice.
Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis.
Exploring the effect of Er miao San-containing serum on macrophage polarization through miR-33/NLRP3 pathway.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Moderate Low UVB Irradiation Modulates Tumor-associated Macrophages and Dendritic Cells and Promotes Antitumor Immunity in Tumor-bearing Mice.
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
γ-Glutamylcysteine rescues mice from TNBS-driven inflammatory bowel disease through regulating macrophages polarization.
miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.
Cadmium contributes to atherosclerosis by affecting macrophage polarization.
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma.
Superior protective effects of PGE2 priming mesenchymal stem cells against LPS-induced acute lung injury (ALI) through macrophage immunomodulation.
Caffeic Acid Phenethyl Ester Suppresses Oxidative Stress and Regulates M1/M2 Microglia Polarization via Sirt6/Nrf2 Pathway to Mitigate Cognitive Impairment in Aged Mice following Anesthesia and Surgery.
Mild treadmill exercise inhibits cartilage degeneration via macrophages in an osteoarthritis mouse model.
Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by microRNA-193a-3p-dependent regulation of plasminogen activator urokinase.
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain.
Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis.
Reversing inflammatory microenvironment by a single intra-articular injection of multi-stimulus responsive lipogel to relieve rheumatoid arthritis and promote joint repair.
Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells.
Lycopene ameliorates islet function and down-regulates the TLR4/MyD88/NF-κB pathway in diabetic mice and Min6 cells.
ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression.
Disturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice.
Determining the chemical profile of Caragana jubata (Pall.) Poir. by UPLC-QTOF-MS analysis and evaluating its anti-ischemic stroke effects.
Tissue-resident CXCR4(+) macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.
Medical Prospect of Melatonin in the Intervertebral Disc Degeneration through Inhibiting M1-Type Macrophage Polarization via SIRT1/Notch Signaling Pathway.
High-intensity interval training in the form of isometric contraction improves fatigue resistance in dystrophin-deficient muscle.
UCHL1 aggravates skin fibrosis through an IGF-1-induced Akt/mTOR/HIF-1α pathway in keloid.
Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury.
Methylene blue targets PHD3 expression in murine microglia to mitigate lipopolysaccharide-induced neuroinflammation and neurocognitive impairments.
DDIT3 aggravates pulpitis by modulating M1 polarization through EGR1 in macrophages.
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Sublethal necroptosis signaling promotes inflammation and liver cancer.
MCP-1-Loaded Poly(l-lactide-co-caprolactone) Fibrous Films Modulate Macrophage Polarization toward an Anti-inflammatory Phenotype and Improve Angiogenesis.
Dual delivery of an NF-κB inhibitor and IL-10 through supramolecular hydrogels polarizes macrophages and promotes cardiac repair after myocardial infarction.
Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes.
[Periodontitis Promotes the Progression of Oral Squamous Cell Carcinoma by Inducing Macrophage M2 Polarization].
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
Chronic docosahexaenoic acid supplementation improves metabolic plasticity in subcutaneous adipose tissue of aged obese female mice.
Exploration of the mechanism by which Huangqi Guizhi Wuwu decoction inhibits Lps-induced inflammation by regulating macrophage polarization based on network pharmacology.
SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer.
Carrier-Free Immunotherapeutic Nano-Booster with Dual Synergistic Effects Based on Glutaminase Inhibition Combined with Photodynamic Therapy.
Acceleration of Oral Wound Healing under Diabetes Mellitus Conditions Using Bioadhesive Hydrogel.
Perfluorooctane sulfonate promotes atherosclerosis by modulating M1 polarization of macrophages through the NF-κB pathway.
The protective effect of gamma aminobutyric acid B receptor activation on sympathetic nerve remodeling via the regulation of M2 macrophage polarization after myocardial infarction.
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.
T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma.
Effects of magnetically targeted iron oxide@polydopamine-labeled human umbilical cord mesenchymal stem cells in cerebral infarction in mice.
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer's disease in APP/PS1 mouse.
4,4'-Methylene diphenyl diisocyanate exposure induces expression of alternatively activated macrophage-associated markers and chemokines partially through Krüppel-like factor 4 mediated signaling in macrophages.
Bionic peptide scaffold in situ polarization and recruitment of M2 macrophages to promote peripheral nerve regeneration.
WNT4 promotes macrophage polarization via granulosa cell M-CSF and reduces granulosa cell apoptosis in endometriosis.
Ischemic Preconditioning Alleviates Cerebral Ischemia-Reperfusion Injury by Interfering With Glycocalyx.
Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy.
The lncRNA H19/miR-29a-3p/SNIP1/c-myc regulatory axis is involved in pulmonary fibrosis induced by Nd2O3.
Copine 1 predicts poor clinical outcomes by promoting M2 macrophage activation in ovarian cancer.
Melatonin-pretreated human umbilical cord mesenchymal stem cells improved endometrium regeneration and fertility recovery through macrophage immunomodulation in rats with intrauterine adhesions†.
Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice.
Scutellarin Acts via MAPKs Pathway to Promote M2 Polarization of Microglial Cells.
TRAF3/STAT6 axis regulates macrophage polarization and tumor progression.
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Hollow copper sulfide nanoparticles carrying ISRIB for the sensitized photothermal therapy of breast cancer and brain metastases through inhibiting stress granule formation and reprogramming tumor-associated macrophages.
KCND2: A prognostic biomarker and regulator of immune function in gastric cancer.
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts.
Constitutive aryl hydrocarbon receptor facilitates the regenerative potential of mouse bone marrow mesenchymal stromal cells.
Loureirin B protects against cerebral ischemia/reperfusion injury through modulating M1/M2 microglial polarization via STAT6 / NF-kappaB signaling pathway.
Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
Irisin attenuates acute lung injury by suppressing the pyroptosis of alveolar macrophages.
Melatonin ameliorates neurological deficits through MT2/IL-33/ferritin H signaling-mediated inhibition of neuroinflammation and ferroptosis after traumatic brain injury.
Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis.
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
Oleoylethanolamide Protects against Acute Ischemic Stroke by Promoting PPARα-Mediated Microglia/Macrophage M2 Polarization.
Electrospun Polycaprolactone (PCL)-Amnion Nanofibrous Membrane Promotes Nerve Regeneration and Prevents Fibrosis in a Rat Sciatic Nerve Transection Model.
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.
Macrophage Extracellular Traps Exacerbate Secondary Spinal Cord Injury by Modulating Macrophage/Microglia Polarization via LL37/P2X7R/NF-κB Signaling Pathway.
The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation.
LncRNA AC099850.3 promotes hepatocellular carcinoma proliferation and invasion through PRR11/PI3K/AKT axis and is associated with patients prognosis.
Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression.
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Characterization of Fatty Acid Metabolism-Related Genes Landscape for Predicting Prognosis and Aiding Immunotherapy in Glioma Patients.
CCR5 as a Prognostic Factor in Lower-Grade Glioma is Involved in the Remodeling of the Tumor Microenvironment.
Digital Spatial Profiling of Individual Glomeruli From Patients With Anti-Neutrophil Cytoplasmic Autoantibody-Associated Glomerulonephritis.
Identification and validation of a 17-gene signature to improve the survival prediction of gliomas.
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Heparin/Collagen-REDV Modification of Expanded Polytetrafluoroethylene Improves Regional Anti-thrombosis and Reduces Foreign Body Reactions in Local Tissues.
Adaptive Gelatin Microspheres Enhanced Stem Cell Delivery and Integration With Diabetic Wounds to Activate Skin Tissue Regeneration.
Vascular endothelial growth factor attenuates neointimal hyperplasia of decellularized small-diameter vascular grafts by modulating the local inflammatory response.
Osteoimmunity-Regulating Biomimetically Hierarchical Scaffold for Augmented Bone Regeneration.
Hirudin alleviates acute ischemic stroke by inhibiting NLRP3 inflammasome-mediated neuroinflammation: In vivo and in vitro approaches.
miR-146a-5p enhances embryo survival in unexplained recurrent spontaneous abortion by promoting M2 polarization of decidual macrophages.
Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn's colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling.
Macrophage-derived extracellular vesicles regulate follicular activation and improve ovarian function in old mice by modulating local environment.
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
Biomechanically-Adapted Immunohydrogels Reconstructing Myelin Sheath for Peripheral Nerve Regeneration.
A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.
Parthenolide modulates cerebral ischemia-induced microglial polarization and alleviates neuroinflammatory injury via the RhoA/ROCK pathway.
Poria cocos polysaccharides rescue pyroptosis-driven gut vascular barrier disruption in order to alleviates non-alcoholic steatohepatitis.
Ultrasound-augmented anti-inflammatory exosomes for targeted therapy in rheumatoid arthritis.
Esomeprazole inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia-reperfusion injury.
Oral Microbiota from Periodontitis Promote Oral Squamous Cell Carcinoma Development via γδ T Cell Activation.
Melatonin-Primed MSCs Alleviate Intrauterine Adhesions by Affecting MSC-Expressed Galectin-3 on Macrophage Polarization.
PARP-inhibition reprograms macrophages toward an anti-tumor phenotype.
Curcumin attenuates cadmium-induced atherosclerosis by regulating trimethylamine-N-oxide synthesis and macrophage polarization through remodeling the gut microbiota.
Fecal microbiota transplantation from young donor mice improves ovarian function in aged mice.
Scalable macroporous hydrogels enhance stem cell treatment of volumetric muscle loss.
Monocyte Recruitment for Vascular Tissue Regeneration.
EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis.
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Naringenin promoted spinal microglia M2 polarization in rat model of cancer-induced bone pain via regulating AMPK/PGC-1α signaling axis.
A biomimetic zeolite-based nanoenzyme contributes to neuroprotection in the neurovascular unit after ischaemic stroke via efficient removal of zinc and ROS.
Facile fabrication of a biocompatible composite gel with sustained release of aspirin for bone regeneration.
Dedicator of Cytokinesis 2 (DOCK2) Silencing Protects Against Cerebral Ischemia/Reperfusion by Modulating Microglia Polarization via the Activation of the STAT6 Signaling Pathway.
Colorectal Cancer-Derived Small Extracellular Vesicles Promote Tumor Immune Evasion by Upregulating PD-L1 Expression in Tumor-Associated Macrophages.
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Circular RNA PLCE1 promotes epithelial mesenchymal transformation, glycolysis in colorectal cancer and M2 polarization of tumor-associated macrophages.
Local delivery of naringin in beta-cyclodextrin modified mesoporous bioactive glass promotes bone regeneration: from anti-inflammatory to synergistic osteogenesis and osteoclastogenesis.
Polymeric indoximod based prodrug nanoparticles with doxorubicin entrapment for inducing immunogenic cell death and improving the immunotherapy of breast cancer.
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
Mussel-inspired collagen-hyaluronic acid composite scaffold with excellent antioxidant properties and sustained release of a growth factor for enhancing diabetic wound healing.
Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.
Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32.
Implantation of a nerve protector embedded with human GMSC-derived Schwann-like cells accelerates regeneration of crush-injured rat sciatic nerves.
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
Human Neural Stem Cell Secretome Inhibits Lipopolysaccharide-Induced Neuroinflammation Through Modulating Microglia Polarization by Activating Peroxisome Proliferator-Activated Receptor Gamma.
Electrospun nanoyarn and exosomes of adipose-derived stem cells for urethral regeneration: Evaluations in vitro and in vivo.
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Glutamine Antagonist Synergizes with Electrodynamic Therapy to Induce Tumor Regression and Systemic Antitumor Immunity.
Coal dust exposure triggers heterogeneity of transcriptional profiles in mouse pneumoconiosis and Vitamin D remedies.
Incorporation of magnesium oxide nanoparticles into electrospun membranes improves pro-angiogenic activity and promotes diabetic wound healing.
A Hierarchical-Structured Mineralized Nanofiber Scaffold with Osteoimmunomodulatory and Osteoinductive Functions for Enhanced Alveolar Bone Regeneration.
Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target.
miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression.
Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy.
ALA-PDT regulates macrophage M1 polarization via ERK/MAPK-NLRP3 pathway to promote the early inflammatory response.
Colchicine-Containing Nanoparticles Attenuates Acute Myocardial Infarction Injury by Inhibiting Inflammation.
Delivery of germacrone (GER) using macrophages-targeted polymeric nanoparticles and its application in rheumatoid arthritis.
Immunomodulatory effect and safety of TNF-α RNAi mediated by oral yeast microcapsules in rheumatoid arthritis therapy.
GABA regulates IL-1β production in macrophages.
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Nicotinamide n-Oxide Attenuates HSV-1-Induced Microglial Inflammation through Sirtuin-1/NF-κB Signaling.
Cell Infiltrative Inner Connected Porous Hydrogel Improves Neural Stem Cell Migration and Differentiation for Functional Repair of Spinal Cord Injury.
Pro-efferocytic macrophage membrane biomimetic nanoparticles for the synergistic treatment of atherosclerosis via competition effect.
Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction.
Microsphere-Gel Composite System with Mesenchymal Stem Cell Recruitment, Antibacterial, and Immunomodulatory Properties Promote Bone Regeneration via Sequential Release of LL37 and W9 Peptides.
Artificial Intelligence-Assisted Bioinformatics, Microneedle, and Diabetic Wound Healing: A "New Deal" of an Old Drug.
DNA Origami as a Nanomedicine for Targeted Rheumatoid Arthritis Therapy through Reactive Oxygen Species and Nitric Oxide Scavenging.
Atractylenolide II inhibits tumor-associated macrophages (TAMs)-induced lung cancer cell metastasis.
MEF2C promotes M1 macrophage polarization and Th1 responses.
Two-stage degradation and novel functional endothelium characteristics of a 3-D printed bioresorbable scaffold.
Zileuton, a 5-Lipoxygenase Inhibitor, Attenuates Haemolysate-Induced BV-2 Cell Activation by Suppressing the MyD88/NF-κB Pathway.
Reactive oxygen species-degradable polythioketal urethane foam dressings to promote porcine skin wound repair.
Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis.
Fe(III)-Chelated Polydopamine Nanoparticles for Synergistic Tumor Therapies of Enhanced Photothermal Ablation and Antitumor Immune Activation.
Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma.
Inhibition of Sphingosine-1-Phosphate Receptor 2 Prevents Thoracic Aortic Dissection and Rupture.
Receptor-Interacting Protein Kinase 3 Inhibition Prevents Cadmium-Mediated Macrophage Polarization and Subsequent Atherosclerosis via Maintaining Mitochondrial Homeostasis.
Sodium Lactate Accelerates M2 Macrophage Polarization and Improves Cardiac Function after Myocardial Infarction in Mice.
lncRNA DCST1-AS1 Facilitates Oral Squamous Cell Carcinoma by Promoting M2 Macrophage Polarization through Activating NF-κB Signaling.
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Gastric Electrical Pacing Reduces Apoptosis of Interstitial Cells of Cajal via Antioxidative Stress Effect Attributing to Phenotypic Polarization of M2 Macrophages in Diabetic Rats.
FSTL3 is a Prognostic Biomarker in Gastric Cancer and is Correlated with M2 Macrophage Infiltration.
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient Prognosis.
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages.
Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.
Identification of an Aging-Related Gene Signature in Predicting Prognosis and Indicating Tumor Immune Microenvironment in Breast Cancer.
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
circ_C20orf11 enhances DDP resistance by inhibiting miR-527/YWHAZ through the promotion of extracellular vesicle-mediated macrophage M2 polarization in ovarian cancer.
Immunohistopathological Analysis of Immunoglobulin E-Positive Epidermal Dendritic Cells with House Dust Mite Antigens in Naturally Occurring Skin Lesions of Adult and Elderly Patients with Atopic Dermatitis.
Bacterial navigation for tumor targeting and photothermally-triggered bacterial ghost transformation for spatiotemporal drug release.
A novel mechanism of lung cancer inhibition by methionine enkephalin through remodeling the immune status of the tumor microenvironment.
peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
A multi-channel collagen scaffold loaded with neural stem cells for the repair of spinal cord injury.
Glial cell line-derived neurotrophic factor ameliorates dextran sulfate sodium-induced colitis in mice via a macrophage-mediated pathway.
Baihui (DU20)-penetrating-Qubin (GB7) acupuncture regulates microglia polarization through miR-34a-5p/Klf4 signaling in intracerebral hemorrhage rats.
Intrauterine inflammation induced white matter injury protection by fibrinogen-like protein 2 deficiency in perinatal mice.
Tetramethylpyrazine Protects Blood-Spinal Cord Barrier Integrity by Modulating Microglia Polarization Through Activation of STAT3/SOCS3 and Inhibition of NF-кB Signaling Pathways in Experimental Autoimmune Encephalomyelitis Mice.
MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway.
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca(2+)/CaMKII/Nrf2 signaling pathway.
Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer.
Chemokine-Induced PBMC and Subsequent MSC Migration Toward Decellularized Heart Valve Tissue.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization.
Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization.
Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization.
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8(+) T cell exclusion.
Eradicating intracellular MRSA via targeted delivery of lysostaphin and vancomycin with mannose-modified exosomes.
Chronic oral exposure to cadmium causes liver inflammation by NLRP3 inflammasome activation in pubertal mice.
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
Preventive and Therapeutic Spermidine Treatment Attenuates Acute Colitis in Mice.
Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.
MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis.
Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages.
Multivalent effects of heptamannosylated β-cyclodextrins on macrophage polarization to accelerate wound healing.
Effective-compound combination inhibits the M2-like polarization of macrophages and attenuates the development of pulmonary fibrosis by increasing autophagy through mTOR signaling.
FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway.
The role of adenosine A(1) receptor in the peripheral tramadol's effect in the temporomandibular joint of rats.
The impact of ExHp-CD (outer membrane vesicles) released from Helicobacter pylori SS1 on macrophage RAW 264.7 cells and their immunogenic potential.
Distinct phenotypic expression levels of macrophages in neonatal lungs.
M2 Macrophage-Derived Exosomal miR-590-3p Attenuates DSS-Induced Mucosal Damage and Promotes Epithelial Repair via the LATS1/YAP/ β-Catenin Signalling Axis.
Deliver Anti-inflammatory Drug Baicalein to Macrophages by Using a Crystallization Strategy.
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Attenuation of Diabetic Nephropathy in Diabetic Mice by Fasudil through Regulation of Macrophage Polarization.
Trichinella spiralis Thioredoxin Peroxidase 2 Regulates Protective Th2 Immune Response in Mice by Directly Inducing Alternatively Activated Macrophages.
Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.
CyTOF Analysis Reveals a Distinct Immunosuppressive Microenvironment in IDH Mutant Anaplastic Gliomas.
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats.
hUC-MSCs ameliorated CUMS-induced depression by modulating complement C3 signaling-mediated microglial polarization during astrocyte-microglia crosstalk.
Blocking P2X7-Mediated Macrophage Polarization Overcomes Treatment Resistance in Lung Cancer.
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Relationship of tumour-associated macrophages with poor prognosis in Wilms' tumour.
ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses.
One-Step Large-Scale Nanotexturing of Nonplanar PTFE Surfaces to Induce Bactericidal and Anti-inflammatory Properties.
Macrophage Spheroids with Chronological Phenotype Shifting To Promote Therapeutic Angiogenesis in Critical Limb Ischemia.
Myeloid-specific dopamine D(2) receptor signalling controls inflammation in acute pancreatitis via inhibiting M1 macrophage.
Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.
TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages.
Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice.
Dexmedetomidine Inhibits Neuroinflammation by Altering Microglial M1/M2 Polarization Through MAPK/ERK Pathway.
Quercetin Promotes Diabetic Wound Healing via Switching Macrophages From M1 to M2 Polarization.
Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice.
The effects of the M2a macrophage-induced axonal regeneration of neurons by arginase 1.
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
The role of CCR5 in the protective effect of Esculin on lipopolysaccharide-induced depressive symptom in mice.
Silica particles disorganize the polarization of pulmonary macrophages in mice.
C/EBP Homologous Protein (CHOP) Activates Macrophages and Promotes Liver Fibrosis in Schistosoma japonicum-Infected Mice.
Electroacupuncture Pretreatment Alleviates Cerebral Ischemic Injury Through α7 Nicotinic Acetylcholine Receptor-Mediated Phenotypic Conversion of Microglia.
Activation of β2-Adrenoceptor Attenuates Sepsis-Induced Hippocampus-Dependent Cognitive Impairments by Reversing Neuroinflammation and Synaptic Abnormalities.
Metformin induces the M2 macrophage polarization to accelerate the wound healing via regulating AMPK/mTOR/NLRP3 inflammasome singling pathway.
Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis.
Metformin ameliorates experimental diabetic periodontitis independently of mammalian target of rapamycin (mTOR) inhibition by reducing NIMA-related kinase 7 (Nek7) expression.
Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system.
Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice.
Baicalein administered in the subacute phase ameliorates ischemia-reperfusion-induced brain injury by reducing neuroinflammation and neuronal damage.
Intestinal autophagy links psychosocial stress with gut microbiota to promote inflammatory bowel disease.
The enhanced effect and underlying mechanisms of mesenchymal stem cells with IL-33 overexpression on myocardial infarction.
NETs promote ALI/ARDS inflammation by regulating alveolar macrophage polarization.
Aedes aegypti saliva impairs M1-associated proinflammatory phenotype without promoting or affecting M2 polarization of murine macrophages.
The effect of Jianpi Yangzheng Xiaozheng Decoction and its components on gastric cancer.
Oral squamous cell carcinoma-derived exosomes promote M2 subtype macrophage polarization mediated by exosome-enclosed miR-29a-3p.
Inhibition of MicroRNA-9-5p Protects Against Cardiac Remodeling Following Myocardial Infarction in Mice.
PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.
Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice.
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Trichosanthes kirilowii lectin ameliorates streptozocin-induced kidney injury via modulation of the balance between M1/M2 phenotype macrophage.
HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization.
Mesenchymal stem cells attenuate sepsis-induced liver injury via inhibiting M1 polarization of Kupffer cells.
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
Protective Effects of Live Combined B. subtilis and E. faecium in Polymicrobial Sepsis Through Modulating Activation and Transformation of Macrophages and Mast Cells.
Burn wounds in the young versus the aged patient display differential immunological responses.
Effects of exposure of adult mice to multi-walled carbon nanotubes on the liver lipid metabolism of their offspring.
Proteomic profile in the mussel Perna viridis after short-term exposure to the brown tide alga Aureococcus anophagefferens.
Prolonged release of bone morphogenetic protein-2 in vivo by gene transfection with DNA-functionalized calcium phosphate nanoparticle-loaded collagen scaffolds.
Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects.
Exosomal MALAT1 derived from oxidized low-density lipoprotein-treated endothelial cells promotes M2 macrophage polarization.
ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Inhibition of HMGB1 mediates neuroprotection of traumatic brain injury by modulating the microglia/macrophage polarization.
Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis.
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Characteristics and potential role of M2 macrophages in COPD.
Spared Nerve Injury Increases the Expression of Microglia M1 Markers in the Prefrontal Cortex of Rats and Provokes Depression-Like Behaviors.
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Interleukin-17A-promoted MSC2 polarization related with new bone formation of ankylosing spondylitis.
PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice.
Sevoflurane preconditioning protects from posttransplant injury in mouse lung transplantation.
(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway.
Alternatively Activated (M2) Macrophage Phenotype Is Inducible by Endothelin-1 in Cultured Human Macrophages.
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model.
CD26 costimulatory blockade improves lung allograft rejection and is associated with enhanced interleukin-10 expression.
Curcumin induces M2 macrophage polarization by secretion IL-4 and/or IL-13.
Granulomas are a source of interleukin-33 expression in pulmonary and extrapulmonary sarcoidosis.
Metabolic and immunomodulatory effects of n-3 fatty acids are different in mesenteric and epididymal adipose tissue of diet-induced obese mice.
Acipinar Ş, Ozkaraca M, Okkay U, Mendil AS
Journal of applied oral science : revista FOB 2026;34:e20250699
Journal of applied oral science : revista FOB 2026;34:e20250699
Photocrosslinkable Chitosan Quaternary Ammonium Salt-Based Ternary Hydrogel with Fibroblast Growth Factor 21 for Diabetic Wound Healing.
Hu J, Xu Y, Zhou D, Chen K, Jiang J, Lin M, Chen W, Wu J, Jiang H, Zhu M, Zhang B, Xu K, Wei P
Biomaterials research 2026;30:0309
Biomaterials research 2026;30:0309
Bioactive Platinum Nanozymes Accelerate Diabetic Wound Healing via Anti-Inflammation and Macrophage Polarization Modulation.
Shi L, Cheng J, Lin L, Liu T, Chen L, Wang X, Cai S, Qiu L, Chen M, Chen Q, Zhong F, Yan F, Chen X, Zeng Y
International journal of nanomedicine 2026;21:586975
International journal of nanomedicine 2026;21:586975
After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway.
Tan Y, Xia J, Liu M, Deng S, Wu H, Qian C
Mediators of inflammation 2026;2026:5595023
Mediators of inflammation 2026;2026:5595023
Platelet-rich plasma-derived microRNA let-7a-5p alleviates knee osteoarthritis by regulating macrophage polarization and improving inflammatory microenvironment.
Li Q, Wang M, Wang D, Nie Y, Sun X, Na L, Yan D, Ma Y, Wang H
Frontiers in immunology 2026;17:1756467
Frontiers in immunology 2026;17:1756467
RP-182 alleviated obstruction-induced renal fibrosis by reprogramming CD206(+) macrophages.
Cao H, Chen X, Jin R, Yang Y, Tao Y, Li P, Wu Y, Chen G, Zhao J, Wen J, Zhao Y, Wei L, Wei Z, Lu D, Chen Y, Liu D, Zhou H, Cheng J
Frontiers in pharmacology 2026;17:1739457
Frontiers in pharmacology 2026;17:1739457
The prognostic significance of JAML and its role in remodeling the immune microenvironment via the cGAS-STING pathway in endometrial cancer.
Tian C, Yao Y, Tu Y, Yu J, Gong C, Shi X, Yu H, Jiang P
Frontiers in immunology 2026;17:1738596
Frontiers in immunology 2026;17:1738596
GCDCA promotes hepatocellular carcinoma progression through S1PR2/PI3K/AKT-mediated polarization of M2-type macrophages.
Xue M, Yu W, Zhang K, Chen Y, Zhang L, Zhang H, Lu S, Tao M, Yan H, Wei L, Lv G, Gao L, Zhang L
Frontiers in immunology 2026;17:1640450
Frontiers in immunology 2026;17:1640450
Prognostic integration of tumor microenvironment and parthanatos-related genes in gastric cancer: a machine learning-driven risk model and immune landscape profiling.
Liu L, Wu M, Liu Y
Frontiers in immunology 2026;17:1636331
Frontiers in immunology 2026;17:1636331
CD146(+) pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis.
Liu W, Duan W, Xia S, Liu Y, Chu H, Liang K, Fang S, Lin M, Wei S, You X, Hu Q, Qi J, Wang Q
Theranostics 2026;16(4):1905-1924
Theranostics 2026;16(4):1905-1924
Electroacupuncture reduces calcium influx and inhibits endoplasmic reticulum stress by inhibiting the PKCδ-TRPA1 pathway to promote motor function recovery after spinal cord injury.
Zhang Y, Liang C, Huang Z, Hu Y, Mo Y, Ning S, Li Z, Wu Y, Zhang J, Li X, Wang Z
Burns & trauma 2026;14:tkaf066
Burns & trauma 2026;14:tkaf066
Aspirin-induced mesenchymal stem cell-derived extracellular vesicles promote osteochondral regeneration by reprogramming macrophages.
Xie C, Peng X, Wang Y, Ma Y, Jiang M, Zhang B, Xia C, Wu Y, Fang H, Wang S
Biomaterials 2026 Sep;332:124151
Biomaterials 2026 Sep;332:124151
ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.
Zhao Y, Zhang Y, Lei T, Zhang S, Nan K, Zhang X, Fan LH
International journal of molecular medicine 2026 May;57(5)
International journal of molecular medicine 2026 May;57(5)
PRSS23 functions downstream of ZEB1 to promote esophageal squamous cell carcinoma progression by driving M2 polarization of tumor associated macrophages.
Chen W, Chen C, Hu Z, Li F, Peng Y, Zhang M
Molecular and cellular biochemistry 2026 May;481(5):2175-2192
Molecular and cellular biochemistry 2026 May;481(5):2175-2192
Antimicrobial peptide chensinin-1b attenuates T2DM progression in atherosclerotic ApoE(-/-) mice.
Qiu Z, Fan F, Li Z, Sun Y, Shang D
Diabetic medicine : a journal of the British Diabetic Association 2026 May;43(5):e70232
Diabetic medicine : a journal of the British Diabetic Association 2026 May;43(5):e70232
Salt-triggered electroactive dressing with controlled drug release for enhanced healing of exudative wounds.
Wu H, He X, Wu L, Zhang Z, Sathishkumar G, Mo F, Zhang K, Yu Y, Kharaziha M, Kang ET, Lu Z, Xu L
Biomaterials 2026 May;328:123887
Biomaterials 2026 May;328:123887
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Cai F, Chen W, Li Q, Chen S, Xu Y, Ren Y, Liu Y
Stem cell reviews and reports 2026 May;22(4):1811-1826
Stem cell reviews and reports 2026 May;22(4):1811-1826
Macrophage Membrane-Cloaked, ROS-Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome.
Li W, Guan Y, Song N, Zhang F, Deng Z, Yin T, Yang Y, Conde J, Jin W, Yin Z
Advanced healthcare materials 2026 May;15(17):e05171
Advanced healthcare materials 2026 May;15(17):e05171
Dietary N-acetylneuraminic acid maintains intestinal homeostasis and protects against aging- and inflammation-associated colonic dysfunction.
Li XX, Shi JN, Guan Z, Zeng SY, Luo Y, Gong XX, He SY, Xu KX, Yang Y, Yin H, Wang ZX, Xie H, Shi LJ
International immunopharmacology 2026 May 15;177:116531
International immunopharmacology 2026 May 15;177:116531
Pomegranate-inspired bionic microgel/periosteum composite harnessing reactive oxygen species for immune-engineered bone regeneration.
Feng Z, Jin M, Li M, Guo J, Guo S, Yang H, Sun X
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114818
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114818
Huangtu Decoction regulates macrophage M1/M2 polarization to alleviate DSS- and rhubarb-induced Deficiency-Cold Pattern in Ulcerative Colitis by inhibiting the HIF-1α signaling pathway.
Chen Y, Wei H, Dai A, Fu Y, Zhang Z, Hong R, Liu H, Jiao Y, Wan J, Chen W
Journal of ethnopharmacology 2026 May 10;362:121353
Journal of ethnopharmacology 2026 May 10;362:121353
Integrative epidemiology and multi-omics reveal a frailty-associated ACKR1 redox axis linking cadmium exposure to atherosclerosis.
Zhang K, Han J, Chen P, Li H, Wu Y, Shi Y, Hou B, Weng W, Wang Y, Zhu Z
Redox biology 2026 Mar;90:104048
Redox biology 2026 Mar;90:104048
Activated ATF6α is a hepatic tumour driver restricting immunosurveillance.
Li X, Lebeaupin C, Kadianaki A, Druelle-Cedano C, Vesper N, Rennert C, Huguet-Pradell J, Gomez Ramos B, Fan C, Piecyk RS, Zizmare L, Ramadori P, Li L, Frick L, Qiu M, Zhang C, Martins Nascentes Melo L, Ranvir VP, Shen P, Hanselmann J, Kosla J, Fernández-Vaquero M, Vucur M, Baskaran P, Bao X, Coleman OI, Tang Y, Cetin M, Chen Z, Jang I, Del Prete S, Rahbari M, Zhang P, Pham TV, Hou Y, Sun A, Gu L, Kim LC, Rothermel U, Heide D, Ali A, Gallage S, Talvard-Balland N, Piqué-Gili M, Gris-Oliver A, Bevilacqua A, Schlicker L, Duffey A, Unger K, Szydlowska M, Hetzer J, Odom DT, Machauer T, Bucci D, Sant P, Lee JH, Rösler J, Meckelmann SW, Schreck J, Murray S, Simon MC, Nahnsen S, Schulze A, Ho PC, Jugold M, Breuhahn K, Mallm JP, Schirmacher P, Roth S, Rahbari N, Tschaharganeh DF, Roessler S, Goeppert B, Bengsch B, Andrieux G, Boerries M, Malek NP, Prinz M, Weber A, Zeiser R, Tamayo P, Bronsert P, Kurowski K, Thimme R, Yuan D, Carretero R, Luedde T, Pinyol R, Hartmann FJ, Karin M, Tasdogan A, Trautwein C, Mall M, Hofmann M, Llovet JM, Haller D, Kaufman RJ, Heikenwälder M
Nature 2026 Mar;651(8106):796-807
Nature 2026 Mar;651(8106):796-807
Immune regulative GelMA&Zn(2+)/Ce(3+)-whitlockite scaffolds with continuous ions release for bone regeneration.
Jin M, Xia M, Wang T, Zhao Y, Xu D, Wu L, Liu T, Li T, Xu D, Yang H, Xu X
Bioactive materials 2026 Mar;57:578-600
Bioactive materials 2026 Mar;57:578-600
Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1.
Wang Y, Fang L, Zhai C, Cai J, Li X, Zong L, Geng Y, Zhu C, Sun C, Dong M, Qian Y, Liu Y, Huang Y, Wang Z, Wang T, Liu WT, Wu Q
CNS neuroscience & therapeutics 2026 Mar;32(3):e70841
CNS neuroscience & therapeutics 2026 Mar;32(3):e70841
SIRT6 Ameliorates Atherosclerosis by Inhibiting M1 Macrophage Polarisation Through Deacetylated-TLR4.
Huang J, Yi H, Wu Y, Zhang W, Ai X
Immunology 2026 Mar 8;
Immunology 2026 Mar 8;
Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage.
Chen Q, Min J, Lu X, Gao Z, Xiong Y
Inflammation 2026 Mar 5;49(1)
Inflammation 2026 Mar 5;49(1)
ZXDB Drives Macrophage Inflammatory Programming in Sepsis-Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation.
Wu H, Gang W, Wang L, Sun J, Li S, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71657
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71657
Cordycepin alleviates ischaemic brain injury by suppressing microglia-induced neuroinflammation via regulating the Notch1 signalling pathway.
Li X, Zhan GF, Zhang X, Zhao YL, Mao M, Xia Q
British journal of pharmacology 2026 Mar 30;
British journal of pharmacology 2026 Mar 30;
Silencing soluble epoxide hydrolase protects against myocardial ischemia-reperfusion injury through modulation of the YAP signaling pathway and macrophage polarization.
Zhao P, Liu S, Yu C
Journal of molecular histology 2026 Mar 24;57(2)
Journal of molecular histology 2026 Mar 24;57(2)
CX3CL1/CX3CR1 axis dysregulation contributes to epileptogenic mechanisms in focal cortical dysplasia.
Lei L, Yang S, Li Y, Tian J, Fang Y, Huang T, Chen S, Zhou L
Acta neuropathologica communications 2026 Mar 20;14(1)
Acta neuropathologica communications 2026 Mar 20;14(1)
Exercise reverses high-fat diet-induced perivascular adipose tissue dysfunction through modulation of UCP2 and TXNIP/NLRP3 pathways.
Hu J, Jiang X, Ding M, Lee SK, Wang L, Li T, Li W, Korivi M
Journal of physiology and biochemistry 2026 Mar 2;82(1)
Journal of physiology and biochemistry 2026 Mar 2;82(1)
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Zhan Y, Zhang Z, Zhang Z, Lin M, Liu H, Abulimiti D, Aihemaiti S, Kan Y, Tan J, Chen X, Tao S
Journal of nanobiotechnology 2026 Mar 17;24(1)
Journal of nanobiotechnology 2026 Mar 17;24(1)
Repeated inhalation exposure to polystyrene nanoplastics induced sustained pulmonary injury and fibrosis in mice.
Han Z, Wang L, Li X, Dai Y, Guan X, Su Z, Li X, Wang X, Li T, Xu M
Ecotoxicology and environmental safety 2026 Mar 15;313:120007
Ecotoxicology and environmental safety 2026 Mar 15;313:120007
Dynamically responsive hydrogel with mechanical stimulation enhances diabetic wound healing via activation of Piezo1-mediated efferocytosis.
Tao Z, Li Z, Shao Y, Xiao Y, Fan X, Yang L, Sun Z, Cui T, Sun Z, Jiang J, Lian X, Guo X, Liu S, Ma X
Bioactive materials 2026 Jun;60:607-625
Bioactive materials 2026 Jun;60:607-625
Lung cancer cell-derived exosomal EHF drives M2 macrophage polarization via transcriptional activation of RNF41 to promote tumor progression.
Chen Z, Ying J, Huang G, Shang W, Shi K, Wang Z, Wang L, Ding D, Zhang C, Tan Y
Regenerative therapy 2026 Jun;32:101104
Regenerative therapy 2026 Jun;32:101104
Rhubarb ameliorates ischemic stroke-induced tryptophan-kynurenine metabolic reprogramming and neuroinflammation via modulation of the IDO-1/TREM-1 pathway.
Liu X, Wang X, Wang Y, Zhu H, Xiang Q, Li Q, Wang X, Xu W, Jiang M, Wang W, Gao J, Wang T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158133
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158133
Dehydroandrographolide succinate alleviates ulcerative colitis via regulating RAB9A/NF-κB axis-mediated macrophage polarization and remodeling the gut microbiota.
Liu J, Mai Y, Xie Y, Zhou X, Ye Y, Jiang D, He L, Ye Z, Li D, Xia C, Su J, Huang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158039
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158039
Celastrol ameliorates depressive-like behaviors in a rat model of post-stroke depression and is associated with reduced neuroinflammation and restoration of serotonergic- and synaptic-related proteins.
Zheng Y, Zhang P, Xie Q, Cao F, Xu L
Brain research bulletin 2026 Jun 1;239:111855
Brain research bulletin 2026 Jun 1;239:111855
Spatiotemporally engineered microneedle for microenvironment remodeling propels mucosal regeneration after tracheal mucosal injury.
Wang P, Ci Z, Zhao E, Hu C, Chen B, Gao E, Bo Q, Bian C, Li Y, Song X, Zhou G, Xu T, Duan L
Bioactive materials 2026 Jul;61:272-289
Bioactive materials 2026 Jul;61:272-289
Shaoyao Gancao Decoction alleviates ulcerative colitis-associated secondary liver injury by inhibiting the phosphorylation of pyruvate dehydrogenase in macrophages.
Tang F, Tang Y, Li L, Zhou F, Sun C, Ouyang B, Huang D, Li M, He W, Pei G, Tan Y
Journal of ethnopharmacology 2026 Jul 15;366:121652
Journal of ethnopharmacology 2026 Jul 15;366:121652
The role of the IL-33/ST2/MAPK signalling pathway in macrophage polarisation and endometrial fibrosis.
Li G, Xu F, Luo S, Jin Y, Yuan L, Yang X, Xuan T, Liu D
International immunopharmacology 2026 Jul 1;180:116743
International immunopharmacology 2026 Jul 1;180:116743
CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis.
Luo X, Xu L, Cai J, Ma S, Song H, Yang P, Yang C
Journal of orthopaedic translation 2026 Jan;56:101005
Journal of orthopaedic translation 2026 Jan;56:101005
Multimerin-1 modulates macrophage M2 polarization and enhances tumor cell stemness in glioblastoma.
Huang C, Yu XB, Zhou YZ, Zhang XB, Dong CM, Bao WQ
Neurological research 2026 Jan;48(1):66-81
Neurological research 2026 Jan;48(1):66-81
Downregulation of the biological macromolecule Spondin-2 disrupts maternal-fetal immune tolerance and trophoblast invasion, driving unexplained recurrent pregnancy loss.
Zhang X, Li PF, Gao Y, Zheng PS
International journal of biological macromolecules 2026 Jan;338(Pt 1):149672
International journal of biological macromolecules 2026 Jan;338(Pt 1):149672
Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty acid synthesis halts pro-fibrotic M2 polarization.
Li J, Zhang Q, Zhao P, Mei X, Shi Y, Shao W, Yu X
International journal of biological macromolecules 2026 Jan;337(Pt 2):149590
International journal of biological macromolecules 2026 Jan;337(Pt 2):149590
SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.
Jiang T, Zhang H, Sun Y, Ji X, Xue L, Pan C, Guo Y, Xu F
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772
Salidroside ameliorates experimental autoimmune neuritis by dually modulating neuroinflammation and immune homeostasis via PI3K/AKT signaling.
Gu T, Wang L, Kang X, Yu C, Shen K, Song M, Gao Y, Wang G, Wang Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00769
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00769
Nanoparticle-Modified Nanofibers Induce Ferroptosis and Stimulate Antitumor Immunity for Melanoma Therapy.
Li M, Li R, Xu B, Lian Y, Yang C, Li J, Liang J, Ding L, Zhang D, Guo J, Fu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e08753
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e08753
Ferroptosis-dependent small extracellular vesicles ULK1 enhances mitophagy and suppresses breast cancer migration.
Wang A, Chen M, Luo Y, Li L, Rong J, Liu L, Yi C
Hereditas 2026 Jan 26;163(1):30
Hereditas 2026 Jan 26;163(1):30
Single-cell transcriptomics uncover RNF130-mediated TNF-α pathway activation and worenine synergy with paclitaxel in breast cancer.
Hu M, Huang L, Deng H, Chen Z, Cheng G, Liu X
Clinical epigenetics 2026 Jan 24;18(1):32
Clinical epigenetics 2026 Jan 24;18(1):32
Rewiring brain structural and functional disconnection with acupuncture in rat model of vascular cognitive impairment and dementia.
Wang L, Zhao JP, Cao Y, Ma SM, Yang JW, Su XT, Huang J, Wang QY, Liu CZ
Biological research 2026 Jan 19;59(1):10
Biological research 2026 Jan 19;59(1):10
Acupuncture as a modulator of microglial polarization and pyroptosis in depression: evidence from a chronic unpredictable mild stress rat model.
Wu X, You Z, Zhang T, Zeng J, Li M, Yan S, Li J, Li P, Shen J, Liu S, Aslam MS, Li J, Ning L, Fang H, Li Y, Yao D, Hao C, Meng X
Metabolic brain disease 2026 Jan 16;41(1):20
Metabolic brain disease 2026 Jan 16;41(1):20
Explore the chemical components of Angong Niuhuang Pill and its potential mechanisms for fever treatment based on UHPLC-Q-Exactive orbitrap HRMS, transcriptomics, and experiment verification.
Gao F, An J, Jia S, Zhu Z, Zhang Z, Li Y, Jiao J, Li S, Liu Y, Yin H, Xu B, Lei H
Journal of ethnopharmacology 2026 Jan 10;354:120542
Journal of ethnopharmacology 2026 Jan 10;354:120542
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
Wu B, Wu J, Bai X, Zhou Q, Wang X
Journal of ethnopharmacology 2026 Jan 10;354:120479
Journal of ethnopharmacology 2026 Jan 10;354:120479
Lithospermic acid regulates macrophage polarization via AMPKα1 activation and ameliorates sepsis associated acute kidney injury in mice.
Li M, Wang S, Ji Y, Cheng Y, Liang J, Qiu W, Zheng S, Zhu Y, Li Y, Lin S, Jiang H, Chen X
International immunopharmacology 2026 Jan 1;168(Pt 1):115822
International immunopharmacology 2026 Jan 1;168(Pt 1):115822
Transcutaneous Auricular Vagus Nerve Stimulation Ameliorates Heart Failure with Preserved Ejection Fraction Through Regulating Macrophage Polarization Mediated by Alpha7nAChR.
Huo JY, Hou C, Jia F, Xue C, Li XL, Yang L, Jiang WY, Zhang X
Cardiovascular drugs and therapy 2026 Feb;40(1):127-140
Cardiovascular drugs and therapy 2026 Feb;40(1):127-140
Self-regulating neohesperidin/silk fibroin composite aerogel for enhanced wound healing via pH-responsive release.
Wang Z, Zhu X, Wang X, Shi Z, Zhang Z, Wang Z, Xie X, Li X, Jiang K, Liu H, Zhou L, Lv D
Materials today. Bio 2026 Feb;36:102637
Materials today. Bio 2026 Feb;36:102637
Clicktetrazine dECM-alginate hydrogels for injectable, mechanically mimetic, and biologically active vocal fold biomaterials.
Brown M, Okuyama H, Li L, Yang Z, Li J, Tabrizian M, Li-Jessen NYK
Biomaterials 2026 Feb;325:123590
Biomaterials 2026 Feb;325:123590
Programmed temporal modulation by using a magnetoelectric wound dressing for ultra-fast early-stage wound healing.
Zhao B, Sun J, Xu Y, Li J, Xie K, Zhou C, Su B, Chen L
Biomaterials 2026 Feb;325:123569
Biomaterials 2026 Feb;325:123569
Blastocyst Structure-Inspired Core-Shell Stem Cell Microspheres with Hyperoside Delivery for Endometrial Regeneration.
Lu S, Xue H, Zhang F, Du Y, Xu X, Liu L, Zhou S, Yang L, Guan Y
Advanced healthcare materials 2026 Feb;15(6):e02293
Advanced healthcare materials 2026 Feb;15(6):e02293
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Ren Z, Wu Z, Wu A, Zhang H, Lu J, Zhang J, Weng J, Zhang J, Chen S, Tan H, Guo T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Construction of a Novel Mucin/Tannic Acid Hydrogel for Diabetic Wound Repair.
Yue Y, Chen G, Cui X, Liao Y, Liu Z, Yang D
Journal of biomedical materials research. Part A 2026 Feb;114(2):e70044
Journal of biomedical materials research. Part A 2026 Feb;114(2):e70044
Kaempferol Alleviates Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Modulating Macrophage M1/M2 Polarization Through RhoA/ROCK-Mediated Mitophagy Activation.
Zhang Y, Zhao Y, Zhang S, Lei T, Xiang B, Zhang X, Nan K, Fan L
Biomedicines 2026 Feb 9;14(2)
Biomedicines 2026 Feb 9;14(2)
Nanoengineered extrusion-aligned tract bioprinting enables functional repair of spinal cord injuries.
Huang W, Chen S, Li K, Ding Y, Zhan B, Zhao D, Xu G, Guo H, Sun C, Yuan R, Gu H, Zhang J, Guo K, Wu J, Dai J, Li W, Zheng X, Feng G, Hu B, Gu Q
Cell stem cell 2026 Feb 5;33(2):340-354.e7
Cell stem cell 2026 Feb 5;33(2):340-354.e7
AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPK-MTOR-autophagy pathway in macrophage.
Chao R, Sun L, Xu X, Liu Z, Xu X, Ren Z, Chen X, Xu W, Chen X, Hu Y, Zhang S
Journal of nanobiotechnology 2026 Feb 3;24(1):130
Journal of nanobiotechnology 2026 Feb 3;24(1):130
Functional border-associated macrophages limit Alzheimer's Disease progression.
Adler D, Pinheiro-Rosa N, Millet A, Gajic ZZ, Cheng E, Gamallo-Lana B, Morizawa Y, Klann E, Gan WB, Mar AC, Ledo JH, Silva HM, Lafaille JJ
bioRxiv : the preprint server for biology 2026 Feb 3;
bioRxiv : the preprint server for biology 2026 Feb 3;
Succinate Mediates Immune-Angiogenic Response by Activating Macrophage M2 Polarization in Oxygen-Induced Retinopathy.
Shen T, Lin R, Zheng T, Yu J, Cai W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71545
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71545
Targeting FAM83D triggers tumor cell senescence via cGAS-STING signaling activation and reprograms TAMs to combat glioma.
Liu H, Lin X, Dai L, Zhang W, Zhang Y, Liu N, Li Y, Peters JJ, Gu J, Peng K, Jiang N, Wanggou S, Li X
Journal of experimental & clinical cancer research : CR 2026 Feb 26;45(1)
Journal of experimental & clinical cancer research : CR 2026 Feb 26;45(1)
Simulated microgravity affects neuronal synaptic plasticity by regulating microglial pro-inflammatory activation.
Chen X, Yuan C, Li Z, Zhao T, Yang Y, Wang Y, Qiao C, Liu Z, Li X
NPJ microgravity 2026 Feb 26;12(1)
NPJ microgravity 2026 Feb 26;12(1)
Biomimetic Selenium-Encrusted Prussian Blue Nanozyme for Myocardial Infarction by Coordinated Enhancement of Mitophagy and Reactive Oxygen Species Scavenging.
Ling H, Liu A, Zhang Y, Lin Q, Song C
ACS nano 2026 Feb 24;20(7):5687-5707
ACS nano 2026 Feb 24;20(7):5687-5707
IL-37 Ameliorates Chronic Endometritis by Attenuating Epithelial-Mesenchymal Transition and Promoting M2 Macrophage Polarization.
Wang Z, Tan J, Zhang R, Liu X, Zhang H, Zhang X
Current issues in molecular biology 2026 Feb 20;48(2)
Current issues in molecular biology 2026 Feb 20;48(2)
The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.
Zhang H, Fu J, Guo Y, Liu S, Mei X, Zeng X, Ren W
Cell chemical biology 2026 Feb 19;33(2):169-182.e5
Cell chemical biology 2026 Feb 19;33(2):169-182.e5
NIR-II-Responsive Biomimetic Nanoplatform for Precise Inhibition of Ischemic Stroke via Dual Modulation of Ion Channels and Microglia.
Liu X, Wu Z, Lv H, Li B, Li C, Zhao J, Li S, Zhang H, Zhang H, Xing C
ACS applied materials & interfaces 2026 Feb 18;18(6):9497-9511
ACS applied materials & interfaces 2026 Feb 18;18(6):9497-9511
Synthetic cleavage-resistant TREM2 boosts macrophage efferocytosis to treat inflammatory diseases.
Dong X, Zhao X, Gao J, Bo L, Li C, Kong Z, Sun W, Xu X, Liu Z, Xiu Q, Zhi Y, Lou J, Li N, Song Y, Jiang X, Zhao K
Cell reports. Medicine 2026 Feb 17;7(2):102580
Cell reports. Medicine 2026 Feb 17;7(2):102580
Carbon-based nanomaterials induce ovarian dysfunction via NLRP3 inflammasome-mediated pyroptosis in granulosa cells.
Wei S, Chen D, Wang J, Wu C, Tang W, Xue L, Feng Y, Dai Y, Guo Y, Zheng P, Song Y, Dai J, Wang S, Wu M
Journal of advanced research 2026 Feb 12;
Journal of advanced research 2026 Feb 12;
Targeting VEGFR2 inhibition within a spatially-confined conduit promotes nerve self-resolution and alleviates mechanical allodynia.
Luo X, Nagayasu T, Zhang Y, He Z, Yang J, Li C, Duan G, Zong Q, Liu Y, Yang K, Mao K, Ma P, Li Z, Zhao Y, Kim K, Zhang J, Wang Z, Luo Y, Lu J, Tong S, Yu JK, Zhao Z, Cao Z, Yang S, Pan Y, Wang X
Bioactive materials 2026 Aug;62:47-63
Bioactive materials 2026 Aug;62:47-63
Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy.
Zhang J, Duan K, Liu Q, Chen S, Zheng H, Liu Y, Qian J, Yin M, Liu J, Li J, Li Z, Chen M, Huang X, Lin F, Gao M, Liao L
Bioactive materials 2026 Aug;62:1-16
Bioactive materials 2026 Aug;62:1-16
Mossy-textured hydroxyapatite-modified poly (lactic-co-glycolic acid) microspheres promote collagen regeneration via calcium/TGF-β and chemokine signaling pathways in soft tissue augmentation.
Chang D, Cao L, Han L, Bai Z, Guo Z, Wang Y, Zheng Y, Sheng J, Tan H, Chen X, Ye F, Guo T, Weng J
Bioactive materials 2026 Apr;58:612-631
Bioactive materials 2026 Apr;58:612-631
HMGA2 promotes hepatocellular carcinoma progression by regulating tumor-associated macrophage via Notch1/CCL2 signaling.
Xing Z, Xun J, Deng L
Molecular and cellular biochemistry 2026 Apr;481(4):1677-1693
Molecular and cellular biochemistry 2026 Apr;481(4):1677-1693
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
Pei X, Wang F, Liu X, Lei Y, Chen Y, Liu B, Sun R, Li P, Bi J, Liu S
Oncogene 2026 Apr;45(12):1128-1144
Oncogene 2026 Apr;45(12):1128-1144
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
Wang C, Wang Y, Li X, Cao H, Wang C, Han S, Chen H, Zhao X, Yang S
Materials today. Bio 2026 Apr;37:102879
Materials today. Bio 2026 Apr;37:102879
The multilayer coatings on polylactic acid implants spatiotemporally regulates the microenvironment to enhance antibacterial and osseointegration capacity.
Lyu J, Jiang S, Ma T, Zhang Y, Yu J, Zhang Z, Teng Z, Helili M, Cao S, Geng X, Wang X, Jiang J, Qiu J, Sun X, Liu X, Ma X
Materials today. Bio 2026 Apr;37:102871
Materials today. Bio 2026 Apr;37:102871
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Mo G, Qing L, Zhang C, Huang L, Yan H, Lu S, Zhang Y, Chen W, Xiang X, Wang N, Han G, Li Y, Jiang L, Zhang J
Materials today. Bio 2026 Apr;37:102779
Materials today. Bio 2026 Apr;37:102779
Polyhedral oligomeric silsesquioxane-functionalized carboxymethyl chitin microspheres via irradiation-induced grafting for hemostasis and tissue repair in post-extraction sockets.
Zhao XY, Lei S, Yan M, Jiang X, Zhang YJ, Liu J, Yang MX, Li LG, Wang CY, Xie C, Li TF, Leng F
International journal of biological macromolecules 2026 Apr;358:151727
International journal of biological macromolecules 2026 Apr;358:151727
Morphologically adaptive microconical hydrogels of gelatin/polyvinyl alcohol with curcumin for diabetic wound repair.
Li R, Zhang L, Luo X, Dong Y, Zhou Y, Yao T, Wu Y, Yuan Q, Qiu X, Guo Q, Yang C, Gou M
International journal of biological macromolecules 2026 Apr;357:151574
International journal of biological macromolecules 2026 Apr;357:151574
3D perfusable minichannels stented with matrix bound vesicles derived from gingival mesenchymal stem cells ameliorated granuloma-related stenosis and improved survival in a rabbit tracheal replacement model.
Liu B, Zhang X, Wei N, Wu X, Yuan P, Zeng T, Liang L, Zhang H, Wu W
Biomaterials 2026 Apr;327:123769
Biomaterials 2026 Apr;327:123769
ANGPT2/Tie2 Enhances H3K18la-Mediated Macrophage M2 Polarization to Promote Endothelial Cell Proliferation in the Chronically Ischaemic Brain.
Tai C, Ling C, Yang Y, Mo N, Yao C, Lv S, Zhang B, Wang H, Chen C
CNS neuroscience & therapeutics 2026 Apr;32(4):e70879
CNS neuroscience & therapeutics 2026 Apr;32(4):e70879
Wine-Processed Cornus officinalis Ameliorates Osteoarthritis via Modulating M1/M2 Macrophage Polarization.
Fu Y, Zhao M, Huang X, Ren Y, Wang W
Journal of cellular and molecular medicine 2026 Apr;30(7):e71113
Journal of cellular and molecular medicine 2026 Apr;30(7):e71113
Parthenolide ameliorates inflammation in sepsis via covalently targeting Trim33 and inhibiting NF-κB pathway.
He X, Wang C, Zhang R, Wang Y, Zhang Y, Yang T, Zhang J, Rao S, Tang H, Peng X, Wang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157862
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157862
Sulforaphane ameliorates DSS-induced colitis and secondary liver injury in mice: Proposed mechanism in the SCFAs-FFAR2/3-macrophage polarization axis.
Ren J, Jiang X, Yu G, Wu W, Chen M, Zhao Y, Yang M, Zou Z, He C
The Journal of nutritional biochemistry 2026 Apr;150:110239
The Journal of nutritional biochemistry 2026 Apr;150:110239
Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression.
Peng S, Lin W, Li Z, Zhuang R, Peng S, Li B, Chen B, Luo Y, Ou Y, Zhuang W, Du T, Li K, Huang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e08588
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e08588
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Xia R, Qi D, Ji B, Dai Y, Kong X
Cancer science 2026 Apr;117(4):1026-1042
Cancer science 2026 Apr;117(4):1026-1042
Histochemical characterization of muscularis macrophage loss and disruption of a miR-93-5p-AHNAK neuro-immune axis in Hirschsprung's disease.
Li X, Bu L, Wang X, Li L, Du G, Wu R, Liu W
Histochemistry and cell biology 2026 Apr 3;164(1)
Histochemistry and cell biology 2026 Apr 3;164(1)
Aerobic Exercise Alleviates Oxidative Stress and Inflammation to Attenuate High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in ApoE(-/-) Mice.
Zhang L, Wang W, Zheng F, Weng J, Lu Y, Li Q, Li T, Li W, Wang L
Metabolites 2026 Apr 21;16(4)
Metabolites 2026 Apr 21;16(4)
Targeting keratin 6 A overcomes gemcitabine resistance by restoring equilibrative nucleoside transporter 1 and TAM-mediated metabolic compensation in pancreatic cancer.
Zhang J, Wang X, Zeng S, Tang B, Yang X, Xie S, Sun H, Wang R, Xia R, Li J, Wang H, Shi Z, Gu J, Wei D
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Apr 17;87:101404
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Apr 17;87:101404
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Zhang H, Chang Y, Fu Q, Jin T, Zhang S, Zhang M
International immunopharmacology 2026 Apr 15;175:116417
International immunopharmacology 2026 Apr 15;175:116417
A pH-Responsive Polyetheretherketone Implant Modified with a Core-Shell Metal-Organic Framework to Promote Antibacterial and Osseointegration Abilities.
Ma S, Yao S, Li Y, Yang Y, Tong T, Zheng H, Ma B, Wei P, Di Z, Zhao B, Deng J
Biomaterials research 2025;29:0188
Biomaterials research 2025;29:0188
The Extracellular Matrix Promotes Diabetic Oral Wound Healing by Modulating the Microenvironment.
Wang Z, Wang L, Wang S, Chen H, Wang D, Li A, Huang Y, Pu Y, Xiong X, Lui X, Huang Y, Guo L
Biomaterials research 2025;29:0169
Biomaterials research 2025;29:0169
IL-1β-Stimulated Bone Mesenchymal Stem Cell-Derived Exosomes Mitigate Sepsis through Modulation of HMGB1/AKT Pathway and M2 Macrophage Polarization.
Li Y, Sun Z, Li Y, Sun J, Chen B
Current molecular medicine 2025;25(1):79-89
Current molecular medicine 2025;25(1):79-89
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Zhi Y, Shu M, Tang P, Li Y, Guo M, Deng J, Mo H, Wu M, Liu B, Mai Y, Ling J, Zhao X, Zhang X, Zuo W
Stem cells international 2025;2025:6324980
Stem cells international 2025;2025:6324980
Chaperonins in Hepatocellular Carcinoma: Unveiling Their Role in Tumor Proliferation and Immune Modulation Through Multiomics Analysis.
Wang SH, Lv FY, Liu YJ, Li JP, Hao JQ, Wang HH
International journal of genomics 2025;2025:6152675
International journal of genomics 2025;2025:6152675
TGF-β-Smad2/3 signaling in high-altitude pulmonary hypertension in rats: Role and mechanisms via macrophage M2 polarization.
Ma W, Ma Y, Bai Y, Guo C, Zhang Q, Su X
Open medicine (Warsaw, Poland) 2025;20(1):20251279
Open medicine (Warsaw, Poland) 2025;20(1):20251279
Prussian Blue Nanoparticle-Induced Alteration of the Polarization State of Tumor-Associated Macrophages as a Substantial Antitumor Mechanism Against Oral Squamous Cell Carcinoma (OSCC).
Zhang Z, Sun X, Gao Z, Lv X, Jia H, Huang B, Xia C, Yang X
International journal of nanomedicine 2025;20:10667-10681
International journal of nanomedicine 2025;20:10667-10681
Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy.
Gao Y, Li L, Zhao F, Cheng Y, Jin M, Xue FS
Drug design, development and therapy 2025;19:369-387
Drug design, development and therapy 2025;19:369-387
Reduced Thioredoxin Regulates IL-1β Secretion via NLRP3 of IL-1β+ Alveolar Macrophages in COPD.
Wang L, Shi R, Li Z, Ma R, Wang C, Xu C, Guo R, Xiao C, Du X, Yang W
Journal of inflammation research 2025;18:8563-8578
Journal of inflammation research 2025;18:8563-8578
Ginger Moxibustion Activates TRPV1 to Modulate the Locus Coeruleus-Spinal Cord-Uterus Pathway and Alleviates Primary Dysmenorrhea in Rats.
Wang X, Yang L, Bi K, Zhou M, Wang D, Zhao Z, Mi S, Li X
Journal of pain research 2025;18:7109-7125
Journal of pain research 2025;18:7109-7125
Mechanistic Study of CD90-Positive Synovial Fibroblasts in the Invasion and Recurrence of Pigmented Villonodular Synovitis.
Kong L, Chen H, Zhang H, Zhang X, Chen J, Nie Y, Su Z, Lin L
Journal of inflammation research 2025;18:17129-17142
Journal of inflammation research 2025;18:17129-17142
Altered Expression of CXCL16/CXCR6 and Its Correlation with Decidual Macrophage Polarization in Preeclampsia.
Huang S, Cao X, Xu Y, Zhu J, Su M
International journal of women's health 2025;17:5411-5423
International journal of women's health 2025;17:5411-5423
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Zhao S, Chen R, An Y, Zhang Y, Ma C, Gao Y, Lu Y, Yang F, Bai X, Zhang J
Frontiers in aging neuroscience 2025;17:1522073
Frontiers in aging neuroscience 2025;17:1522073
TENS alleviates CP/CPPS-related inflammation and pain by modulating Kir2.1-dependent macrophage polarization.
Hong T, Liu X, Chi Z, Liu G, Zhang Y, Lin X, Yao P, Gong Q, Zhang Y, Hong X
Frontiers in immunology 2025;16:1683500
Frontiers in immunology 2025;16:1683500
Serglycin's role in primary liver cancer: insights into tumor microenvironment and macrophage interaction.
Lian Q, Ma C, Wang X, Wang J, Zeng J, Zhang J, Li Y
Frontiers in immunology 2025;16:1668627
Frontiers in immunology 2025;16:1668627
Bone marrow mesenchymal stem cells alleviate smoke inhalation injury by regulating alveolar macrophage polarization via the CD200-CD200R pathway.
Ding Z, Zhuang Y, Zhao Y, Shi J, Guo X, Fan H, Lv Q
Frontiers in immunology 2025;16:1645460
Frontiers in immunology 2025;16:1645460
Resistance training alleviates muscle atrophy and muscle dysfunction by reducing inflammation and regulating compromised autophagy in aged skeletal muscle.
Cao Y, Zhou J, Quan H, Li W, Li T, Wang L
Frontiers in immunology 2025;16:1597222
Frontiers in immunology 2025;16:1597222
Cordycepin, lactoferrin, and Sargassum fusiforme polysaccharides protects against RSV via M2-like macrophage polarization.
Fu X, Huang P, Zhang Y, Li Y, Hu S
Frontiers in immunology 2025;16:1576069
Frontiers in immunology 2025;16:1576069
Ganoderma lucidum spore powder alleviates rheumatoid arthritis-associated pain hypersensitivity through inhibiting accumulation, N1 polarization, and ROS production of neutrophils in mice.
Huang S, Zhan Z, Xu F, Liu X, Fang Z, Wu W, Liang Z, Liu G, Wang M, da Silva HS, Luo X, Mo K
Frontiers in immunology 2025;16:1569295
Frontiers in immunology 2025;16:1569295
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Zheng Z, Lin L, Lin H, Zhou J, Wang Z, Wang Y, Chen J, Lai C, Li R, Shen Z, Zhong M, Xie C, Chen Y, Zhang X, Guo Z, Dong R, He S, Chen F
Frontiers in immunology 2025;16:1559966
Frontiers in immunology 2025;16:1559966
Prognostic significance and immune infiltration analysis of HMGA2 in endometrial cancer.
Jiang P, Yu J, Zheng Y, Tian C, Tu Y, Gong C, Yu H, Luo Y, Hu Z
Frontiers in immunology 2025;16:1559278
Frontiers in immunology 2025;16:1559278
Hydrogen sulfide as a therapeutic agent for diabetic wounds: effects on inflammation and fibroblast pyroptosis.
Zhao F, Li Y, Hu Q, Xu J, Zhang N, Chen Y, Jiang X, Gu C, Zhang K, Wu G
Frontiers in immunology 2025;16:1558443
Frontiers in immunology 2025;16:1558443
Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfusion injury.
Tang Q, Xie J, Wang Y, Dong C, Sun Q
Frontiers in immunology 2025;16:1510500
Frontiers in immunology 2025;16:1510500
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment.
Xiu Z, Zhu Y, Li X, Jiang X, Feng Y, He L, Li C, Cai R, Tao G
Theranostics 2025;15(9):3750-3780
Theranostics 2025;15(9):3750-3780
Bioinspired exosome-SiO(2) nanohybrid therapeutic for rheumatoid arthritis treatment.
Zhu Q, Chen R, Wu X, Zhou Y, Wang Z, Zhang H, Zhu H, Sun L, Shuai Z
Theranostics 2025;15(13):6553-6571
Theranostics 2025;15(13):6553-6571
Polyphenol and metal ion-reinforced supermolecular hydrogels incorporating nanofiber drug and peptide for annulus fibrosus regeneration.
Xin L, Li X, Yang Y, Chen P, Li Y, Liu J, Chen K, Su P, Feng S, He S, Xu X, Wang W, Xu W
Theranostics 2025;15(12):5756-5771
Theranostics 2025;15(12):5756-5771
Pathological and immune features of non-tuberculous mycobacteria and Mycobacterium tuberculosis cutaneous/mucosa infections of fifty-four biopsies.
Zhang XY, Li Y, Zhao J, Deng FQ, Tang XH, Li JF, Yang WT, Jiang HW, He JH, Wang Z
Frontiers in cellular and infection microbiology 2025;15:1664902
Frontiers in cellular and infection microbiology 2025;15:1664902
Ansofaxine Hydrochloride inhibits hepatocellular carcinoma growth and enhances targeted therapy through the EGFR/MAPK pathway.
He Y, Tao Q, Mo S, Chen M, Wang J, Zhai H, Hong S, Gao Q, Zhang G, Han C, Shi X
Frontiers in oncology 2025;15:1523570
Frontiers in oncology 2025;15:1523570
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Ren X, Wang Z, Wang J, Li X, Wei H, Liu C, Liu S, Zhu Y, Feng C, Yin Y, Tian Y, Wu M, Zeng X
ImmunoTargets and therapy 2025;14:151-173
ImmunoTargets and therapy 2025;14:151-173
A multifunctional dihydromyricetin-loaded hydrogel for the sequential modulation of diabetic wound healing and glycemic control.
Li H, Wen H, Zhang H, Cao X, Li L, Hu X, Zhang Y, Shen X, Shubhra QTH, Yang H, Cai X
Burns & trauma 2025;13:tkaf024
Burns & trauma 2025;13:tkaf024
Exosome-related immune signatures and peripheral blood assays predict prognosis and immunotherapy response in hepatocellular carcinoma.
Gao R, Mi L, Shi J, Zhang M, Duan X, Zhao M, Yin F
Frontiers in cell and developmental biology 2025;13:1696790
Frontiers in cell and developmental biology 2025;13:1696790
The effect of ponicidin on CFA-induced chronic inflammatory pain and its mechanism based on network pharmacology and molecular docking.
Wang P, Jiang H, Yao J, He G, Tao T, Qin Z
Frontiers in medicine 2025;12:1510271
Frontiers in medicine 2025;12:1510271
Metabolic reprogramming of tumor-associated macrophages via adenosine-A(2A)R signaling drives cross-resistance in non-small cell lung cancer.
Ding W, Mo J, Su Y, Zhang Q, Sun D, Yao X, Liu G, Ye J, Wu Y, Xue M, Yue P, Lu J, Zhang J, Shi Y, Hu W, Zhu K, Wang Y, Zhang X
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Sep;82:101272
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Sep;82:101272
Tremella fuciformis Polysaccharides Alleviate Early Brain Injury in Experimental Subarachnoid Hemorrhage by Inhibiting the KDR-Mediated P38 MAPK/NF-κB Pathway.
Wan YH, Cheng ZJ, Fan LX, Yang DH, Chen BL, Chen XX, Zhu Q
Molecular neurobiology 2025 Sep;62(9):11112-11129
Molecular neurobiology 2025 Sep;62(9):11112-11129
Engineered nerve guide conduit enhances peripheral nerve regeneration by modulating the microenvironment through macrophage-triggered cascade reactions.
Yang X, Liang X, Wang B, Gao X, Yang W, Li J, Cai H, Tong Z, Chen Y
Bioactive materials 2025 Sep;51:46-69
Bioactive materials 2025 Sep;51:46-69
Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere.
Liu X, Ma B, Hu S, Li D, Pan C, Xu Z, Chen H, Wang Y, Wang H
Biomaterials 2025 Sep;320:123253
Biomaterials 2025 Sep;320:123253
Peptide-Enhanced Bioactive Hydrogel Combined with Photodynamic-Phage Synergistic Antibacterial Therapy System Accelerates Infected Wound Healing.
Quan L, Xin Y, Zhang Z, Zhou C, Ao Q
Advanced healthcare materials 2025 Sep;14(24):e2500875
Advanced healthcare materials 2025 Sep;14(24):e2500875
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Zhou Y, Xu T, Zhou Y, Chen N, Wu Z, Yang Z, Yang C, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Electroacupuncture promotes myelin repair in the corpus callosum region of cerebral ischemic rats by modulating microglia activation and polarization.
Wang W, Chan C, Wang X, Wu F
Neurological research 2025 Sep 9;:1-12
Neurological research 2025 Sep 9;:1-12
Isoacteoside alleviates LPS-induced depressive-like behaviors in mice by inhibiting neuroinflammation through regulating microglial polarization and oxidative stress.
Bi J, Zhang H, Wei J, Huang X, Dong Y, Dong Y, Xie Y, Li R, Chen S, Zhao Z, Cheng B
Behavioral and brain functions : BBF 2025 Sep 29;21(1):30
Behavioral and brain functions : BBF 2025 Sep 29;21(1):30
Tongqiao huoxue decoction in improving vascular cognitive impairment in rats through PI3K-AKT pathway.
Wu J, Wang J, Sun M, Zhang Y, Li X, Xu Y, Zhu B, Gu X
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120262
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120262
RHBDF2 governs microglial neuroinflammation during cerebral ischemia-reperfusion injury and is positively regulated by the m6A reader YTHDF1.
Xu L, Zhang R, Zhang X, Liu B, Shang X, Huang D
Molecular medicine (Cambridge, Mass.) 2025 Sep 2;31(1):284
Molecular medicine (Cambridge, Mass.) 2025 Sep 2;31(1):284
Microenvironment responsive nanoplatform for targeted removal of cholesterol and reshaping inflammatory microenvironment in atherosclerotic plaques.
Shen L, Jiang C, Song J, Bi Y, Chen W, Lu C, Chen M, Lv L, Yu R, Zou J, Zhao Z, Chen X, Ji J
Journal of controlled release : official journal of the Controlled Release Society 2025 Sep 10;385:114000
Journal of controlled release : official journal of the Controlled Release Society 2025 Sep 10;385:114000
Polyphyllin I enhances the anti-tumor efficacy of Palbociclib by reversing M2 macrophage polarization in lung cancer.
Jiang Y, Wang L, Chen Y, Li Y, Chen G, Lu Y, Jiang C, Chai K, Wang Y
Biochemical and biophysical research communications 2025 Sep 1;777:152228
Biochemical and biophysical research communications 2025 Sep 1;777:152228
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
Zhang M, Liu S, Wu Z, Wang C, Zhang H, Yang J, Guo C, Dai M, Wang X, Ren W
Science China. Life sciences 2025 Oct;68(10):3037-3050
Science China. Life sciences 2025 Oct;68(10):3037-3050
Dual stimulus-responsive dECM cryogel sequentially regulate bone microenvironment for one-step surgical therapy of chronic osteomyelitis.
Liu H, Liu S, Liao L, Liao H, Pan W, Hu J
Materials today. Bio 2025 Oct;34:102243
Materials today. Bio 2025 Oct;34:102243
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Ming P, Li K, Zhu W
Materials today. Bio 2025 Oct;34:102236
Materials today. Bio 2025 Oct;34:102236
Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.
Wang X, Zhong Y, Qian B, Huang S, Long Q, Zhang H, Zhao Q, Ye X
Materials today. Bio 2025 Oct;34:102205
Materials today. Bio 2025 Oct;34:102205
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Gao X, Wu S, Yao Z, Shao Y, Feng J, Yuan Z, Mao H
Materials today. Bio 2025 Oct;34:102104
Materials today. Bio 2025 Oct;34:102104
Orally-deliverable liposome-microgel complexes dynamically remodel intestinal environment to enhance probiotic ulcerative colitis therapy via TLR4 inhibition and tryptophan metabolic crosstalk.
Fu Y, Wang T, Ge X, Wen H, Fei Y, Li M, Luo Z
Biomaterials 2025 Oct;321:123339
Biomaterials 2025 Oct;321:123339
Columbianadin targets TRIM7 to maintain P2X7 palmitoylation, inhibiting cuproptosis in synovial M2 macrophages.
Li Z, Huang Z, Liao X, Li H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157091
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157091
PDPK1 governs macrophage M2 polarization via hypoxia-driven CD47/AKT-glycolytic Axis in endometriosis.
Li H, Chai X
Cellular signalling 2025 Oct;134:111922
Cellular signalling 2025 Oct;134:111922
Effects of higenamine on M1/M2 polarization and osteoclast differentiation in rheumatoid arthritis via the THBS-1/TGF-β signaling pathway.
Chen DT, Wan ZJ, Sheng XP, Rao W, Zhan XH, Gu JL, Wei XZ, Fan TY
Cellular signalling 2025 Oct;134:111905
Cellular signalling 2025 Oct;134:111905
miR-21-5p Alleviates Retinal Ischemia-Reperfusion Injury by Inhibiting M1 Polarization of Microglia via Suppression of STAT3 Signaling.
Qin L, Liao J, Tan C, Liu C, Shi W, Chen D
Biomedicines 2025 Oct 9;13(10)
Biomedicines 2025 Oct 9;13(10)
Injectable Immune-Regulating Mesenchymal Stem Cells Hydrogel for Localized Scleroderma Treatment.
Liu R, Kong B, Lu J, Zhao Y, Sun L
ACS nano 2025 Oct 7;19(39):34785-34796
ACS nano 2025 Oct 7;19(39):34785-34796
Intratumoral microbiota-driven macrophage reprogramming in pancreatic cancer via Blautia metabolite 6-hydroxyhexanoic acid.
Zhong Y, Zhang D, Ding F, Zhang H, Guo Y, Huang Q, Liu G, Zhang X, Weng S
International immunopharmacology 2025 Oct 30;164:115421
International immunopharmacology 2025 Oct 30;164:115421
Hypoxia-Induced Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization and Enhance Angiogenesis to Promote Diabetic Wound Healing.
Su Y, Lu J, Liang F, Cheng J
Biomolecules 2025 Oct 24;15(11)
Biomolecules 2025 Oct 24;15(11)
M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis.
Chen M, Li Y, Yang Z, Chen M, Li J, Bao G, Ma L, Hu J
Stem cell research & therapy 2025 Oct 15;16(1):569
Stem cell research & therapy 2025 Oct 15;16(1):569
Pterostilbene as a pyroptosis inducer and tumor microenvironment regulator inhibits glioblastoma and enhances the efficacy of immunotherapy.
Chen Z, Fang XG, Jia LJ, Feng Y, Cheng JH, Luo S, Wen S, Wei JR, Ma SN, Guo XR, Luo J
International immunopharmacology 2025 Oct 10;163:115247
International immunopharmacology 2025 Oct 10;163:115247
TFAP4/DLGAP5 promotes tumor progression and macrophage M2 polarization in prostate cancer by activating the JAK2/STAT3 signaling.
Li S, Dong Q, Ren W, Sun Y, Wang Z, Pan L
Experimental cell research 2025 Oct 1;452(2):114753
Experimental cell research 2025 Oct 1;452(2):114753
The Crosstalk Between Sepsis-Associated Encephalopathy and Alzheimer's Disease: Identifying Potential Biomarkers and Therapeutic Targets for Cognition.
Wang Z, Zhang Z, Shi J, Zhao R
Molecular neurobiology 2025 Nov;62(11):13999-14014
Molecular neurobiology 2025 Nov;62(11):13999-14014
Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex.
Ju J, Wang C, Nie F, Tian H, Yin Q, Liu J, Wang S, Yang P, Du Y
International endodontic journal 2025 Nov;58(11):1725-1737
International endodontic journal 2025 Nov;58(11):1725-1737
Upregulation of ACSL1 in synovial macrophages promotes lipid peroxidation via the IκB/NF-κB pathway to accelerate osteoarthritis.
Yao Z, Yuan Z, Li Y, Li X, Peng C, Jin J, Zhang H, Bai X, Pan J, Cai D
Journal of orthopaedic translation 2025 Nov;55:360-375
Journal of orthopaedic translation 2025 Nov;55:360-375
Isopimpinellin: A Promising Treatment for Colitis-Related Colorectal Cancer That Targets ALOX5-Mediated Macrophage Polarization.
Zhan M, Yi Q, Yu L, Li Q, Jiang M, Wu D, Jian M, Cao H, Bin D
Phytotherapy research : PTR 2025 Nov;39(11):5249-5262
Phytotherapy research : PTR 2025 Nov;39(11):5249-5262
Structural characterization and medium-chain acyl-coenzyme a dehydrogenase-mediated anti-inflammatory mechanism of a Hulless barley Monascus polysaccharide in ulcerative colitis.
Xiong H, Bai S, Ouyang H, Xie L, Feng Y, Cheng J, Luo Y
International journal of biological macromolecules 2025 Nov;330(Pt 3):148033
International journal of biological macromolecules 2025 Nov;330(Pt 3):148033
Jolkinolide B Mitigates Cerebral Ischemia-Reperfusion Injury by Promoting Microglial M1/M2 Polarization Through the JAK2/STAT3 Signaling Pathway.
Guo Y, Dong X, Liu M, Liu D, Wang J, Guo S
CNS neuroscience & therapeutics 2025 Nov;31(11):e70653
CNS neuroscience & therapeutics 2025 Nov;31(11):e70653
Dexmedetomidine alleviates sepsis-induced acute lung injury by inhibiting M1 macrophage polarization via inhibition of PKM2-mediated Warburg effect.
He Y, Xie W, Zhou H, Wang Y, Chen L, Xu Z, Feng Y, Liu G, Liu J, Li X, Lv Y, Bai Y, Hu D, Wu Q
Biochemical pharmacology 2025 Nov;241:117130
Biochemical pharmacology 2025 Nov;241:117130
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Chen J, Zhu T, Yang X, Yang Z, Shen M, Gu B, Wang D, Zhang Y, Zhang M, Sun S, Yu J, Yan C
Free radical biology & medicine 2025 Nov;239:155-176
Free radical biology & medicine 2025 Nov;239:155-176
Decoupling Half-Process Assisted Mitochondrial Transplantation via Self-Stripping pHLIP Boosts Macrophages Reprogramming for Inflammation Resolution.
He P, Wu X, Li M, Liu K, Chen Y, Zhang Q, Cheng H, Li Y, Yang S
Small (Weinheim an der Bergstrasse, Germany) 2025 Nov;21(45):e07970
Small (Weinheim an der Bergstrasse, Germany) 2025 Nov;21(45):e07970
AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
Nie W, Gong C, Liu Y, Yang J, Dai Q, Liao Y, Li F
Molecular immunology 2025 Nov;187:240-253
Molecular immunology 2025 Nov;187:240-253
Protocatechuic aldehyde promotes diabetic wound healing by enhancing angiogenesis via H3K18 lactylation-mediated Acvr1c expression.
Fan W, You Y, Qu Y, Liu G
Molecular immunology 2025 Nov;187:152-165
Molecular immunology 2025 Nov;187:152-165
Evaluation of a novel bioceramic sealer NeoSEALER Flo on the activation and polarization of macrophage.
Wang Z, Sun X, Chen Z, Yu J, Chen Z, Chang Z, Zhu L, Wang L
Odontology 2025 Nov 7;
Odontology 2025 Nov 7;
The Leupaxin/HDAC6/EGR2 axis facilitates breast cancer progression by enhancing macrophage M2 polarization.
He S, Wang Q, He J, Chen Z, Xiao Y
Cell biology and toxicology 2025 Nov 25;41(1):154
Cell biology and toxicology 2025 Nov 25;41(1):154
A murine distal femoral epiphysis ischemia model reveals spatiotemporal stratification of necrotic bone marrow clearance and associated inflammatory responses.
Zhao M, Feng Z, Tang S, Liao S, Ding X
Journal of orthopaedic surgery and research 2025 Nov 23;20(1):1098
Journal of orthopaedic surgery and research 2025 Nov 23;20(1):1098
Modified Xiaoyao San ameliorates LPS-induced depression-like behavior by inhibiting NLRP3-mediated microglial pyroptosis.
Tian L, Su P, Feng G, Peng S, Liu L, Yan X, Liu X, Li Y, Bai M, Wang B, Xu E
Metabolic brain disease 2025 Nov 22;40(8):324
Metabolic brain disease 2025 Nov 22;40(8):324
The miR-125a-5p/IRF4 Axis Mediates Sodium Arsenite-Induced M2 Macrophage Polarization.
Yu Y, Yao F, Tong S, Li M, Liao Q, Wang F, Xi S
Biomolecules 2025 Nov 20;15(11)
Biomolecules 2025 Nov 20;15(11)
11-keto-β-boswellic acid and Z-guggulsterone suppress HMGB1/TLR4 pathway activity and modulate microglial polarization to remodel perineuronal nets after nerve injury.
Liao Y, Yang L, Ding Y, Guo C, Hu J, Xu X, Zhu H, Yang J, Zhao M
Journal of advanced research 2025 Nov 2;
Journal of advanced research 2025 Nov 2;
Omentin-1 reduced synovial M1 macrophages through SIRT6 signaling pathway and alleviated knee osteoarthritis response in mice.
Wu H, Sun W, Zhang Q, Cheng G, Cao Z
Arthritis research & therapy 2025 Nov 18;27(1):216
Arthritis research & therapy 2025 Nov 18;27(1):216
Carnosine protects against cerebral ischemia/reperfusion injury through promoting microglial M2 polarization via SIRT1/NF-κB signaling pathway.
Ran R, Wang Y, Liu Y, Wang D, Wu N, Zhao Y, Yang J
European journal of pharmacology 2025 Nov 15;1007:178191
European journal of pharmacology 2025 Nov 15;1007:178191
A hydrogel-based nanoparticles sustained-release system selectively targeting pro-inflammatory microglia for spinal cord injury repair.
Ma W, Kong Y, Sheng X, Liu T, Zhang K, Wen R, Liu D, Long G, Li X
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114180
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114180
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Pang P, Liu Y, Song H, Ye Z, Zhou H, Zhang R, Kumeria T, She W, Xu C, Mei PL, He Y, Ye Q
Diabetes 2025 Nov 1;74(11):2060-2074
Diabetes 2025 Nov 1;74(11):2060-2074
Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury.
Fan Z, Jia M, Zhou J, Zhu Z, Wu Y, Lin X, Qian Y, Lian J, Hua X, Dong J, Fang Z, Liu Y, Chen S, Xue X, Yue J, Zhu M, Wang Y, Huang Z, Teng H
Neural regeneration research 2025 Nov 1;20(11):3287-3301
Neural regeneration research 2025 Nov 1;20(11):3287-3301
Th22 cells promote the transition from homeostatic to reactive microglia in diabetic encephalopathy.
Yu SX, Yu HD, Wang YF, Yao TF, Lv SZ, Wang YC, Li JQ, Liu WQ, Ding JY, Liu XZ, Zuo ZF, Liu WP
Acta diabetologica 2025 May;62(5):633-650
Acta diabetologica 2025 May;62(5):633-650
GIV/Girdin Modulation of Microglial Activation in Ischemic Stroke: Impact of FTO-Mediated m6A Modification.
Xie P, Xia M, Long T, Guo D, Cao W, Sun P, Yu W
Molecular neurobiology 2025 May;62(5):5501-5517
Molecular neurobiology 2025 May;62(5):5501-5517
Platelet activation stimulates macrophages to enhance ulcerative colitis through PF4/CXCR3 signaling.
Niu Y, Li A, Xu W, Zhang R, Mei R, Zhang L, Zhou F, Pan Q, Yan Y
International journal of molecular medicine 2025 May;55(5)
International journal of molecular medicine 2025 May;55(5)
Restoring tendon microenvironment in tendinopathy: Macrophage modulation and tendon regeneration with injectable tendon hydrogel and tendon-derived stem cells exosomes.
Li D, Li S, He S, He H, Yuan G, Ma B, Zhang Y, Yuan C, Liu Z, Deng Z, Xu J
Bioactive materials 2025 May;47:152-169
Bioactive materials 2025 May;47:152-169
Hyaluronic acid-modified PtPdCo-CQ nanocatalyst with triple enzyme-like activities regulates macrophage polarization and autophagy levels for the treatment of rheumatoid arthritis.
Zhang L, Wu G, Yao J, Wang D, Gao F, Qian Z
International journal of biological macromolecules 2025 May;309(Pt 4):143143
International journal of biological macromolecules 2025 May;309(Pt 4):143143
Electroacupuncture alleviates diesel exhaust particles-induced inflammatory response in lung through dopamine inhibition of NLRP3 signaling pathway.
Xie Y, Han J, Wang Q, Fang X, Pan B, Han D, Li J, Shao W, Hong X, Tu W, Geng W, Li W, Tian Z, Chen R, Xu Y, Kan H
Ecotoxicology and environmental safety 2025 May;296:118184
Ecotoxicology and environmental safety 2025 May;296:118184
Temporal and spatial expression of Phosphodiesterase-4B after sciatic nerve compression in rats and its mechanism of action on sciatic nerve repair.
Wang Y, Zhou Y, Liu J, Liu C, Li Z, Sun X
Neurochemistry international 2025 May;185:105940
Neurochemistry international 2025 May;185:105940
Mg(2+)-Loaded Black Phosphorus Nanosheet Protects against Cerebral Ischemic Injury through Anti-Oxidative and Anti-Inflammatory Effects.
Wang M, Xia X, Li Y, Zhang K, Cheng X, Wen X, Zhao L, Guo X, Song F, Cheng A
Advanced healthcare materials 2025 May;14(13):e2500929
Advanced healthcare materials 2025 May;14(13):e2500929
Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose-Derived Stem Cells.
Long Q, Liu C, Zheng H, Wang M, Liu H, Liu Y, Cao Z, Sun Y, Mo Q, Backman LJ, Zhu J, Hu L, Huang J, Zhang W, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2417447
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2417447
Myeloid but not hepatocytic CD38 is a key driver for hepatic ischemia/reperfusion injury.
Zhao QH, Zhang YT, Wen K, Ding Q, Chen ZY, Tula D, Li JH, Zhou J, Xiao YF, Guan XH, Deng KY, Wang LF, Xin HB
Signal transduction and targeted therapy 2025 May 9;10(1):150
Signal transduction and targeted therapy 2025 May 9;10(1):150
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
Zhou J, Wu K, Ma Y, Zhu J, Zhou Y, Zhang Z, Li F, Zeng G, Li S, Tan S, Zhang Y, Wan C, Tu T, Lin Q, Liu Q
International immunopharmacology 2025 May 8;154:114561
International immunopharmacology 2025 May 8;154:114561
Astragaloside III inhibits MAPK-mediated M2 tumor-associated macrophages to suppress the progression of lung Cancer cells via Akt/mTOR signaling pathway.
Sun Y, Liu JQ, Chen WJ, Tang WF, Zhou YL, Liu BJ, Wei Y, Dong JC
International immunopharmacology 2025 May 8;154:114546
International immunopharmacology 2025 May 8;154:114546
M2 macrophages activate the IL-10/JAK2/STAT3 pathway to induce pathological microangiogenesis in the nucleus pulposus exacerbating intervertebral disc degeneration.
Zhang SP, Tong M, Mo J, Dong ZY, Huang YF
Journal of orthopaedic surgery and research 2025 May 28;20(1):532
Journal of orthopaedic surgery and research 2025 May 28;20(1):532
Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response.
Wang Z, Guo W, Zhang X, Wei Y, Zhang W, Du N, Li C, Wu X, Yi F, Zhou T, Dong X, Guo Q, Xu H, Wang E, Li N, Cheng R, Li Z, Song X, Sun Y, Sun X, Cao L
Cell reports 2025 May 27;44(5):115679
Cell reports 2025 May 27;44(5):115679
L-Kynurenine regulates immune response in ICIs-associated myocarditis via JAK/STAT pathway.
He X, Zhang J, Zhang Y, Li H, Chen Y, Zhang H, Pan J, Zhou Y, Zhang S, Cheng L
International immunopharmacology 2025 May 27;156:114676
International immunopharmacology 2025 May 27;156:114676
Therapeutic potential of ADSC-derived exosomes in acute lung injury by regulating macrophage polarization through IRF7/NLRP3 signaling.
Ren J, Lei G, Dong A, Cao S, Han X, Li H
International immunopharmacology 2025 May 27;156:114658
International immunopharmacology 2025 May 27;156:114658
M2-ApoBDs as a therapeutic strategy for systemic lupus erythematosus: targeted macrophage reprogramming and treg differentiation.
Ji J, Yang S, Xu Y, He Q, Liang Q, Feng G, Xia Y, Yang M, Huang Y, Yang J, Dong C, Zhao R, Wang Y, Guo G, Sha X, Li J, Guo Y, Gu Z
Journal of nanobiotechnology 2025 May 16;23(1):354
Journal of nanobiotechnology 2025 May 16;23(1):354
KLF15 regulates macrophage polarization patterns in deep vein thrombosis.
Li J, Xiang Y, Shentu H, Yang X, Yang J, Ge W, Song E
International immunopharmacology 2025 May 16;155:114632
International immunopharmacology 2025 May 16;155:114632
Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB.
Liu Y, Zhao W, Lv X, Wu G, Zhou X, Tian H, Qv X, Sun H, He Y, Zhang Y, Wang C, Tian J
International immunopharmacology 2025 May 16;155:114588
International immunopharmacology 2025 May 16;155:114588
IL-27 accelerates diabetic wound healing by modulating macrophage polarization.
Tao L, Wu S, Wang Q, Xi Z, Zou Y, Cao M, Liang K, Xu W, Hu Q, Ge Y, Yin Z, Ju Z, Liu Z
International immunopharmacology 2025 May 16;155:114575
International immunopharmacology 2025 May 16;155:114575
Astragaloside IV prevents liver fibrosis by blocking glycolysis-mediated macrophage M1 polarization.
Hu Y, Kuang M, Song H, Tan Y, Zhou F, Pei G, Jiao L
European journal of pharmacology 2025 May 15;995:177353
European journal of pharmacology 2025 May 15;995:177353
Chemotherapy-induced macrophage CXCL7 expression drives tumor chemoresistance via the STAT1/PHGDH-serine metabolism axis and SAM paracrine feedback to M2 polarization.
Liu S, Gong H, Li P, Hu J, Li Y, Xu R, Cai J, Wang S, Cai J, Ma H, Mi X, Li Y, Zhou Q, Zhou Q, Yang W, Li R, Song L, Fang L
Cell death & disease 2025 May 14;16(1):379
Cell death & disease 2025 May 14;16(1):379
Bta-miR-93 regulates the maternal-fetal tolerance in dairy cows via promoting Programmed Cell Death Ligand 1 mediated M2 macrophage polarization†.
Yang C, Feng X, Guo Y, Shaukat A, Wu Z, Chen Y, Meng L, Deng G
Biology of reproduction 2025 May 13;112(5):880-894
Biology of reproduction 2025 May 13;112(5):880-894
An active shrinkage and antioxidative hydrogel with biomimetic mechanics functions modulates inflammation and fibrosis to promote skin regeneration.
Zhang T, Zhong XC, Feng ZX, Lin XY, Chen CY, Wang XW, Guo K, Wang Y, Chen J, Du YZ, Zhuang ZM, Wang Y, Tan WQ
Bioactive materials 2025 Mar;45:322-344
Bioactive materials 2025 Mar;45:322-344
Multifunctional sericin-based biomineralized nanoplatforms with immunomodulatory and angio/osteo-genic activity for accelerated bone regeneration in periodontitis.
Ming P, Li B, Li Q, Yuan L, Jiang X, Liu Y, Cai R, Zhou P, Lan X, Tao G, Xiao J
Biomaterials 2025 Mar;314:122885
Biomaterials 2025 Mar;314:122885
Conductive hyaluronic acid/phytanic acid hydrogel to deliver recombinant human amelogenin for diabetic wound repair.
Cui X, Yue Y, Li Z, Shi X, Qian C, Liu Z, Lin J
International journal of biological macromolecules 2025 Mar;297:139864
International journal of biological macromolecules 2025 Mar;297:139864
Early intervention with pericyte Fli-1 post-TBI attenuates hippocampal BBB disruption and subsequent neuroinflammation with neurological deficits.
Li J, Du M, Dong G, Hu D, Zhang H, Yu Z, Lu Y, Yang Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167671
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167671
Immune checkpoint inhibitors mediate myocarditis by promoting macrophage polarization via cGAS/STING pathway.
Cao Z, Zhang Y, Jia H, Sun X, Feng Y, Wu H, Xu B, Wei Z
Cytokine 2025 Mar;187:156873
Cytokine 2025 Mar;187:156873
Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.
Lei X, Zhao D, Chen T, Li Q, Xue A, Hu Z, Jia F, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365
Tetrahydroxy Stilbene Glycoside Reduces Abeta Deposition by Modulating Microglia Activation and via TREM2/PI3K/AKT Pathway in APP/PS1 Mice.
Li M, Song Q, Jie S, Wang C, Zhang C, Chi K, Gao Y, Li T
Basic & clinical pharmacology & toxicology 2025 Mar;136(3):e70008
Basic & clinical pharmacology & toxicology 2025 Mar;136(3):e70008
KLHDC8A knockdown in normal ovarian epithelial cells promoted the polarization of pro-tumoral macrophages via the C5a/C5aR/p65 NFκB signaling pathway.
Fang J, Wang J, Zhao X, Yang Y, Xiao Y
Cellular immunology 2025 Mar-Apr;409-410:104913
Cellular immunology 2025 Mar-Apr;409-410:104913
Rapid angiogenic hydrogel nanofiber scaffold promotes random flap regeneration and modulates inflammation.
Liang J, Zou Y, Ju H, Lv Y
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2025 Mar-Apr;33(2):e70028
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2025 Mar-Apr;33(2):e70028
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Jia S, Shi N, Lu M, Wang X, Qi Y, Wang X, Zhao J, Jiang D
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p.
Yang Q, Chen Q, Zhang KB, Liu Y, Zheng JC, Hu DX, Luo J
Acta neuropathologica communications 2025 Mar 5;13(1):48
Acta neuropathologica communications 2025 Mar 5;13(1):48
Luteolin modulates liver macrophage subtype polarization and play protective role in sepsis induced acute hepatic injury.
Deng L, Yu Q, Kuang G, Wang L, Fan J, Ye L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Mar 28;74(1):59
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Mar 28;74(1):59
The role of Morin in attenuating atherosclerosis via STAT1 pathway inhibition.
Ji X, Dong Q, Li W, Luo W, Zhou N, Li H, Yang X
Biochemical and biophysical research communications 2025 Mar 25;754:151537
Biochemical and biophysical research communications 2025 Mar 25;754:151537
Adhesion-Assisted Antioxidant-Engineered Mesenchymal Stromal Cells for Enhanced Cardiac Repair in Myocardial Infarction.
Zhong X, Luo L, Wu J, Li W, Liu X, Ye T, Li Z, Shi P
ACS nano 2025 Mar 25;19(11):11412-11426
ACS nano 2025 Mar 25;19(11):11412-11426
Adverse Outcome Pathway-Based Strategies to Mitigate Ag(2)Se Quantum Dot-Induced Neurotoxicity.
Yao Y, Wang Z, Huang X, Wei T, Liu N, Zou L, Niu Y, Hu Y, Fang Q, Wang X, Qiao D, Li C, Chen M, Guan S, Xue Y, Wu T, Zhang T, Tang M
ACS nano 2025 Mar 25;19(11):11029-11048
ACS nano 2025 Mar 25;19(11):11029-11048
Platelet Membrane and miR-181a-5p Doubly Optimized Nanovesicles Enhance Cardiac Repair Post-Myocardial Infarction through Macrophage Polarization.
Liu D, Wang X, Liu Z, Ding L, Liu M, Li T, Zeng S, Zheng M, Wang L, Zhang J, Zhang F, Li M, Liu G, Tang Y
ACS applied materials & interfaces 2025 Mar 19;17(11):16520-16532
ACS applied materials & interfaces 2025 Mar 19;17(11):16520-16532
Immune-mediated regeneration of cell-free vascular grafts in an ovine model.
Nasiri B, Das A, Ramachandran K, Bhamidipati SH, Wu Y, Venkatesan S, Gunawan R, Swartz DD, Andreadis ST
NPJ Regenerative medicine 2025 Mar 19;10(1):13
NPJ Regenerative medicine 2025 Mar 19;10(1):13
Biomimetic gold nano-modulator for deep-tumor NIR-II photothermal immunotherapy via gaseous microenvironment remodeling strategy.
Huang H, Xie Z, Li N, Zeng L, Zeng Q, Yang Z, Shen J, Yang H, Liu Y, Wu C
Journal of nanobiotechnology 2025 Mar 18;23(1):220
Journal of nanobiotechnology 2025 Mar 18;23(1):220
Corilagin enhances wound healing by modulating the macrophage phenotype in diabetic mice.
Li Y, Yu S, Zeng J, Zhou S, Cui X, Zhou J, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70439
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70439
Administration of Porphyromonas gingivalis in pregnant mice enhances glycolysis and histone lactylation/ADAM17 leading to cleft palate in offspring.
Zhao X, Zheng X, Wang Y, Chen J, Wang X, Peng X, Yuan D, Liu Y, Wang Z, Du J
International journal of oral science 2025 Mar 13;17(1):18
International journal of oral science 2025 Mar 13;17(1):18
Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment.
Zhu Y, Xiu Z, Jiang X, Zhang H, Li X, Feng Y, Li B, Cai R, Li C, Tao G
Journal of nanobiotechnology 2025 Mar 12;23(1):205
Journal of nanobiotechnology 2025 Mar 12;23(1):205
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
Wang T, Chen J, Shu C, Shen X, Fu Y, Li M, Luo Z
Acta biomaterialia 2025 Mar 1;194:396-410
Acta biomaterialia 2025 Mar 1;194:396-410
LCN2 Regulates Microglia Polarization Through the p38MAPK-PGC-1α-PPARγ Pathway to Alleviate Traumatic Brain Injury.
Du H, Lai J, Lin B, Pan J, Zhou Y, Feng Y
Cell biochemistry and biophysics 2025 Jun;83(2):2301-2311
Cell biochemistry and biophysics 2025 Jun;83(2):2301-2311
Multifunctional injectable hydrogel incorporating EGCG-Cu complexes for synergistic antibacterial, immunomodulatory, and osteogenic therapy in periodontitis.
Hu Y, Xu W, Sun L, Ma X, Zhou P, Zhang C, Cai R, Wang X, Yang H, Tao G, Chen J, He Y
Materials today. Bio 2025 Jun;32:101907
Materials today. Bio 2025 Jun;32:101907
Macrophage membrane functionalized composite microspheres promote bone regeneration in periodontitis via manipulating inflammation reversing-osteogenesis coupling.
Song R, Wan Z, Yuan X, Wang N, Gao Y, Zhang L, Ren H, Jin Y, Liu X, Sang J, Yuan Z, Zhao Y
Materials today. Bio 2025 Jun;32:101789
Materials today. Bio 2025 Jun;32:101789
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
Su S, Bai J, Wang R, Gao S, Zhou R, Zhou F
Materials today. Bio 2025 Jun;32:101759
Materials today. Bio 2025 Jun;32:101759
3D bioprinted biomimetic MOF-functionalized hydrogel scaffolds for bone regeneration: Synergistic osteogenesis and osteoimmunomodulation.
Yu SY, Wu T, Xu KH, Liu RY, Yu TH, Wang ZH, Zhang ZT
Materials today. Bio 2025 Jun;32:101740
Materials today. Bio 2025 Jun;32:101740
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment.
Yi G, Li M, Zhou J, Li J, Song X, Li S, Liu J, Zhang H, Chen Z
Materials today. Bio 2025 Jun;32:101697
Materials today. Bio 2025 Jun;32:101697
Green synthesis of silver nanoparticles using Fructus Aurantii-loaded Citrus pectin hydrogel for accelerated healing of MRSA-infected diabetic wounds.
Chang L, Ahmad B, Tong A, Wu Z, Xu P, Gao Z, Yin C, Luan M, Tong C, Liu B
International journal of biological macromolecules 2025 Jun;315(Pt 1):144222
International journal of biological macromolecules 2025 Jun;315(Pt 1):144222
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Tang Y, Ye J, Xu T, Sun Y, Meng W, Zhu L, Jia Z, Wu Q, Chen D, Wu F
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation.
Ge S, Qiu B, Liu R, Sun L, Yang L, Chen X, Tao H, Yang W, Yu Y, Wang D
Biochemical pharmacology 2025 Jun;236:116879
Biochemical pharmacology 2025 Jun;236:116879
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Luo Z, Zheng S, Hu Z, Li P, Zeng J, Lu Y, Ali M, Chen Z, Wang Q, Qi F
Free radical biology & medicine 2025 Jun;233:302-316
Free radical biology & medicine 2025 Jun;233:302-316
Myeloid-specific deficiency of group VIA calcium-independent phospholipase A2 preconditions myeloid cells for injury resolution after acetaminophen exposure.
Xu F, Jansakun C, Li G, Biswas U, Poschet G, Staffer S, Tuma-Kellner S, Nakchbandi I, Merle U, Chamulitrat W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jun;187:118146
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jun;187:118146
TREM2 activation reduces white matter injury via PI3K/Akt/GSK-3β signalling after intracerebral haemorrhage.
Zhang Y, Shi Y, Wang L, Li Z, Wang Y, Yan J, Sun X, Luo Q, Li L
British journal of pharmacology 2025 Jun;182(11):2542-2559
British journal of pharmacology 2025 Jun;182(11):2542-2559
Gallic acid promotes M2 macrophage polarization through mitochondrial oxidative phosphorylation in periodontitis.
Zhang R, Yang W, Li K, Zhang X, Liu J, Ai L
Archives of oral biology 2025 Jun;174:106237
Archives of oral biology 2025 Jun;174:106237
IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway.
Song M, Zhang G
Diabetology & metabolic syndrome 2025 Jun 5;17(1):193
Diabetology & metabolic syndrome 2025 Jun 5;17(1):193
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Pei X, Liu J, Wei Y, Zhu Y, Li Y, Wang Q, Zhuang L, Jin G
International immunopharmacology 2025 Jun 5;157:114786
International immunopharmacology 2025 Jun 5;157:114786
Enhanced engraftment and immunomodulatory effects of integrin alpha-2-overexpressing mesenchymal stromal cells in lipopolysaccharide-induced acute lung injury.
Kang H, Kim OH, Chang ES, Kim J, Kim JY, Shin GS, Kim CH, Lim Y, Seo YJ, Kim JW, Lee HJ
Stem cell research & therapy 2025 Jun 3;16(1):286
Stem cell research & therapy 2025 Jun 3;16(1):286
miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.
Hou D, Hu Y, Li H, Yang G
International immunopharmacology 2025 Jun 26;159:114882
International immunopharmacology 2025 Jun 26;159:114882
SPI1 upregulated LILRB2 to enhance the immunosuppressive phenotype of LPS-tolerant macrophages by inhibiting TLR8-mediated MyD88/NF-κB signaling.
Bai R, Guo J
Biology direct 2025 Jun 23;20(1):73
Biology direct 2025 Jun 23;20(1):73
Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway.
Fan Z, Ye L, Wang S, Zhu Z, Wu C, Wu C, Kong L, Ning R
Neuromolecular medicine 2025 Jun 19;27(1):47
Neuromolecular medicine 2025 Jun 19;27(1):47
Polyphosphate- and Antioxidant Peptide-Based Coacervate Delivers miRNA.
Wang C, Xu X, Dai S, Xie Z, Lu J, Wang B, Zhang F, Zhou R, Du Y, Tian B
ACS applied materials & interfaces 2025 Jun 18;17(24):34951-34964
ACS applied materials & interfaces 2025 Jun 18;17(24):34951-34964
Betulinic acid enhances autopahgy to promote microglial M2 polarization and alleviate inflammation via AMPK-HDAC5-KLF2 signaling pathways in spinal cord injury.
He Z, Xu Y, Zhang Y, Jin M, Sun Y, Tang F, Qiu C, Junior AMA, Cai Y, Xu X, Chen X, Chen K, Xiang G, Xiao J, Wang J, Wang J, Chen B
International immunopharmacology 2025 Jun 17;158:114889
International immunopharmacology 2025 Jun 17;158:114889
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Feng CZ, Zhong SQ, Ye SW, Zheng Z, Sun H, Zhou SH
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
PDGFC secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and immunosuppression in lung adenocarcinoma.
Cui M, Ding X, Jiang Y, Zhang L, Cao W, Wang Y, Sheng Z, Sun W, Guo A, Gu L, Zhang X, Duan W, Shi L, Zhang B
Acta biochimica et biophysica Sinica 2025 Jun 11;57(10):1625-1635
Acta biochimica et biophysica Sinica 2025 Jun 11;57(10):1625-1635
Platelet Membrane-Coated Drug-Loaded Nanoparticles for Dual-Modal Imaging and Photodynamic Therapy in Triple-Negative Breast Cancer.
Ma K, Yang M, Pan Y, Bao Y, Bao Y, Mai X
ACS applied materials & interfaces 2025 Jun 11;17(23):33513-33527
ACS applied materials & interfaces 2025 Jun 11;17(23):33513-33527
Fate reversal: Exosome-driven macrophage rejuvenation and bacterial-responsive drug release for infection immunotherapy in diabetes.
Zou J, Cui W, Deng N, Li C, Yang W, Ye X, Yao F, Zhang T, Xiao J, Ma C, Wu L, Dong D, Chen J, Guo C, Liu A, Wu H
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113730
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113730
Secretome enriched with small extracellular vesicles derived from human gingiva-derived mesenchymal stem cells enhances rat tongue muscle regeneration.
Zhang Q, He P, Shi S, Xu Q, Granquist EJ, Winkelstein BA, Shanti RM, Le AD
Journal of nanobiotechnology 2025 Jun 10;23(1):434
Journal of nanobiotechnology 2025 Jun 10;23(1):434
M2 macrophage derived exosomal miR-20a-5p ameliorates trophoblast pyroptosis and placental injuries in obstetric antiphospholipid syndrome via the TXNIP/NLRP3 axis.
Zhang H, Jiang N, Xu M, Jing D, Dong T, Liu Q, Lv Q, Huo R, Chen P, Li L, Wang X
Life sciences 2025 Jun 1;370:123561
Life sciences 2025 Jun 1;370:123561
GDF11 Regulates M1 and M2 Polarization of BV2 Microglial Cells via p38 MAPK Signaling Pathway.
Zhao X, Qin R, Li G, Lv G, Zhao D, Kong L, Qi M, Li P
Molecular neurobiology 2025 Jul;62(7):9290-9305
Molecular neurobiology 2025 Jul;62(7):9290-9305
Cannabinoid Receptor-2 Alleviates Sepsis-Induced Neuroinflammation by Modulating Microglia M1/M2 Subset Polarization Through Inhibiting Nogo-B Expression.
Chen S, Li Z, Yang L, Xu Z, Liu A, He Q, Xiao F, Zhan J
Molecular neurobiology 2025 Jul;62(7):9258-9270
Molecular neurobiology 2025 Jul;62(7):9258-9270
Oncostatin-M functionalized cryogel microspheres for promoting diabetic bone defects regeneration.
Song R, Yuan X, Wan Z, Zhang L, Rao F, Zhao Y, Yuan Z
Journal of orthopaedic translation 2025 Jul;53:138-148
Journal of orthopaedic translation 2025 Jul;53:138-148
Human dental follicle cell-derived conditioned media enhance periodontal regeneration by regulating the osteogenic differentiation and inflammation of periodontal ligament stem cells and macrophage polarization.
Gao Y, He X, Deng Y, Wang X, Shen J, Xu W, Cai R, Lan X, Chen J, He Y
Molecular and cellular biochemistry 2025 Jul;480(7):4431-4448
Molecular and cellular biochemistry 2025 Jul;480(7):4431-4448
Hyaluronic acid methacryloyl hydrogel with sustained IL-10 release promotes macrophage M2 polarization and motor function after spinal cord injury.
Wang Z, Li D, Wang Y, Yuan P, Zhang W, Zhang Y, He F, Yang J, Bi H, Duan H
Journal of biomaterials applications 2025 Jul;40(1):3-19
Journal of biomaterials applications 2025 Jul;40(1):3-19
A glycopeptide-based pH-responsive hydrogel promotes diabetic wound healing via antimicrobial and remodeling microenvironment.
Xie H, Tian S, Cui C, Sun C, Hu Y, Tang C, Gao D, Lu L, Jin L, Xu F, Lin J, Fu H, Liang X, Zhao L, Kong F, Wei X, Sun W, Li M, Li H
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114614
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114614
Notch signaling pathway regulates the progression of fetal growth restriction through mediating immune dysfunction.
Ye L, Zheng X, Yang Y, Lyu Y
Biomedical reports 2025 Jul;23(1):111
Biomedical reports 2025 Jul;23(1):111
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Jin X, Liu S, Fang J, Chen F, Xu B, Nan L, Zhao S, Wu Z, Guan Z, Tao K, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
The mechanism of action of GLUT1 in promoting NETs-mediated impairment of macrophage phenotypic switching based on macrophage-fibroblast interplay.
Li W, Li S, Sun W, Han D
Cytokine 2025 Jul;191:156946
Cytokine 2025 Jul;191:156946
M2 Macrophage-Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1(hi) Neutrophils to Enhance Inflamed Bone Regeneration.
Yao Y, Yin Y, Shuai F, Lam W, Zhou T, Xie Y, He X, Han X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2416159
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2416159
Evidence for imbalanced polarization of caruncle macrophages in retained placenta of dairy cows.
Zhang H, Li M, Zhao B, Chang R, Wang J, Yang Y, Huang Q, Aernouts B, Jiang Q, Loor JJ, Xu C
Journal of dairy science 2025 Jul;108(7):7437-7451
Journal of dairy science 2025 Jul;108(7):7437-7451
DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy.
Ma J, Wang X, Sun D, Chen J, Zhou L, Zou K, Ni X, Jin H, Lin J
Stem cell research & therapy 2025 Jul 9;16(1):356
Stem cell research & therapy 2025 Jul 9;16(1):356
M2 macrophage-secreted KYNU promotes stemness remodeling and malignant behavior in endometrial cancer via the SOD2-mtROS-ERO1α-UPR(ER) axis.
Pan X, Wang W, Wang Y, Gu J, Ma X
Journal of experimental & clinical cancer research : CR 2025 Jul 4;44(1):193
Journal of experimental & clinical cancer research : CR 2025 Jul 4;44(1):193
Icariin delivery system based on covalent organic framework materials: dual effects of immune modulation and osteogenesis promotion.
Luo M, Lin X, Wang N, Xie Q, Zeng S, Li S, He Z, Lan X
RSC advances 2025 Jul 4;15(29):23783-23800
RSC advances 2025 Jul 4;15(29):23783-23800
A cell-free SHED lysate-hydrogel system for oral ulcer healing with anti-inflammatory and pro-angiogenic effects.
Dong N, Zhang C, Zhang Q, Bao S, Hu Y, Xu H, Dai P, Li C, Li S, Wu P, Xu J, Cai X, Wang Z, Luo L
Journal of nanobiotechnology 2025 Jul 28;23(1):547
Journal of nanobiotechnology 2025 Jul 28;23(1):547
Wenxia Changfu formula inhibits Lewis lung cancer metastasis by reprogramming tumor-associated macrophages through the PPAR-γ/CD36 pathway.
Yin X, Sun X, Li A, Ruan J, Niu H, Zhou Y, Chen G, Guo J, He Q, Ji X
Journal of ethnopharmacology 2025 Jul 24;351:120103
Journal of ethnopharmacology 2025 Jul 24;351:120103
Targeted Inhibition of Aldose Reductase by Isoliquiritigenin Suppresses Fatty Acid Synthesis to Inhibit Macrophage M2 Polarization and Alleviate Pulmonary Fibrosis.
Mei X, Zhang Q, Shao W, Zheng J, Zhao P, Li J
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18252-18267
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18252-18267
Biomimetic Nanoparticles Simultaneously Targeting Modulation of Lipid Metabolism and Phenotype of Macrophages for Programmed Atherosclerosis Management.
Dong X, Suo Y, Yu J, Yu F, Li F, Zheng J, Li G, Ma S, Hao Y, Zhang H, Liu B, Jiang Y
ACS nano 2025 Jul 22;19(28):25628-25644
ACS nano 2025 Jul 22;19(28):25628-25644
Cellular Landscape of Synovial Chondromatosis Synovium Revealed by Single-Cell RNA Sequencing.
Zhao H, Jiang F, Zhang P, Bi Y, Shen Y, Ma J, Gong J, Han K, Zhang L, Yu T, Xiao X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70799
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70799
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Lin S, Ji Z, Gao J, Fan J, Hou J, Liu S, Wang C, Chen K, Tao L, Jiang Z
Life sciences 2025 Jul 15;373:123681
Life sciences 2025 Jul 15;373:123681
Double-Layer Nucleoside-Microneedles Co-Delivering Dexamethasone Vesicles and Adenosine Overcome Pseudomembrane Barriers for the Treatment of Oral Ulcer.
Zhang B, Qian Y, Li J, Fan Y, Gao M, Wu Q, Li Z, Hu Y, Du J
ACS nano 2025 Jul 15;19(27):25204-25227
ACS nano 2025 Jul 15;19(27):25204-25227
Integrative proteomics and metabolomics analyses reveals the regulation of autophagy and ferroptosis by RAB10 through Slc37a2/mTOR pathway in breast cancer.
Ji Y, Li R, Tang G, Xiao Y, Ye R, Shi J, Geng C, Ran R, Zhu C, Wang W, Chen C, Yang Q
Cellular and molecular life sciences : CMLS 2025 Jul 14;82(1):275
Cellular and molecular life sciences : CMLS 2025 Jul 14;82(1):275
Microglial exosome TREM2 ameliorates ferroptosis and neuroinflammation in alzheimer's disease by activating the Wnt/β-catenin signaling.
Zhu L, Zhou T, Wu L, Zhu X, Chen L, Zhang M, Zhou J, Wang F
Scientific reports 2025 Jul 10;15(1):24968
Scientific reports 2025 Jul 10;15(1):24968
SESN3 restrains the progress of idiopathic pulmonary fibrosis by targeting the activity of FOSL2.
Sun Y, Chen D, Liu F, Liu T
Biology direct 2025 Jul 1;20(1):76
Biology direct 2025 Jul 1;20(1):76
A Zinc-Citrate Metal-Organic Framework-Based Adaptable Hydrogen Sulfide Delivery System for Regulating Neuroregeneration Microenvironment in Spinal Cord Injury.
Yao Y, Dong X, Pang Z, Shao J, He Z, Liu K, Hou P, Hu F, Liu W, Huo Y, Wang H, Dai H, Zhang X
ACS nano 2025 Jul 1;19(25):22798-22819
ACS nano 2025 Jul 1;19(25):22798-22819
Nuclear receptor subfamily 1 group D member 2 induces chemoresistance in ovarian cancer by regulating ferroptosis and immune infiltration.
Wang L, Shao N, Qu Y, Sun H, Zhao J
Discover oncology 2025 Jul 1;16(1):1215
Discover oncology 2025 Jul 1;16(1):1215
Tumor-associated macrophages derived exosomal circPLK1 promotes resistance to EGFR inhibitor osimertinib in non-small cell lung cancer.
Li C, Sun X, Wang Z
Discover oncology 2025 Jul 1;16(1):1196
Discover oncology 2025 Jul 1;16(1):1196
Highly BBB-permeable nanomedicine reverses neuroapoptosis and neuroinflammation to treat Alzheimer's disease.
Xie A, Cheng G, Wu J, Li Z, Yu G, Zhu X, Chen T
Biomaterials 2025 Jan;312:122749
Biomaterials 2025 Jan;312:122749
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
He Y, Peng E, Ba X, Wu J, Deng W, Huang Q, Tong Y, Shang H, Zhong Z, Liu X, Zhang Y, Ye T, Yang X, Wang K, Xie Y, Jiang K, Xia D, Chen Z, Tang K
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Protective role of Yougui Yin in experimental knee osteoarthritis: From the perspective of macrophage polarization.
Wu Z, Xu K, Chen M, Wang S, Ma Y
Prostaglandins & other lipid mediators 2025 Jan;176:106940
Prostaglandins & other lipid mediators 2025 Jan;176:106940
An Optimized Decellularized Extracellular Matrix from Dental Pulp Stem Cell Sheets Promotes Axonal Regeneration by Multiple Modes in Spinal Cord Injury Rats.
Qiu W, Zhou B, Luo Y, Chen Y, Chen Z, Wu K, Wu H, Wu B, Guo J, Fang F
Advanced healthcare materials 2025 Jan;14(1):e2402312
Advanced healthcare materials 2025 Jan;14(1):e2402312
Inhibition of PKM2 by shikonin impedes TGF-β1 expression by repressing histone lactylation to alleviate renal fibrosis.
Xiang T, Wang X, Huang S, Zhou K, Fei S, Zhou B, Yue K, Li Q, Xue S, Dai Y, Zhang J, Ni H, Sun C, Huang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156324
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156324
Ginsenoside RK3 inhibits glioblastoma by modulating macrophage M2 polarization via the PPARG/CCL2 axis.
Zhang H, Hu J, Zhao X, Zheng B, Han Y, Luo G, Dou D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156271
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156271
The Anti-Inflammatory Effects of Formononetin, an Active Constituent of Pueraria montana Var. Lobata, via Modulation of Macrophage Autophagy and Polarization.
Xu L, Zhou S, Li J, Yu W, Gao W, Luo H, Fang X
Molecules (Basel, Switzerland) 2025 Jan 6;30(1)
Molecules (Basel, Switzerland) 2025 Jan 6;30(1)
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.
Liu M, Xie WJ, Zhang X, Wu W, Li G, Wang L
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31
STEAP3-SLC39A8-mediated microglia ferroptosis involved in neurotoxicity in rats after exposure to lead and cadmium combined.
Sun Y, Liu J, Xiao K, Chen S, Ma J, Cao M, Yang Y, Shao H, Cui G, Du Z
International immunopharmacology 2025 Jan 27;146:113854
International immunopharmacology 2025 Jan 27;146:113854
ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation.
Chang Y, He Y, Wang D, Zhang K, Zhang Y, Li Z, Zeng S, Xiao S, Pan S, Huang K
Acta neuropathologica communications 2025 Jan 27;13(1):16
Acta neuropathologica communications 2025 Jan 27;13(1):16
Extracellular Matrix-Mimicking Hydrogel with Angiogenic and Immunomodulatory Properties Accelerates Healing of Diabetic Wounds by Promoting Autophagy.
Pan Y, Li Y, Zhou X, Luo J, Ding Q, Pan R, Tian X
ACS applied materials & interfaces 2025 Jan 22;17(3):4608-4625
ACS applied materials & interfaces 2025 Jan 22;17(3):4608-4625
Nitric Oxide-Releasing Mesoporous Hollow Cerium Oxide Nanozyme-Based Hydrogel Synergizes with Neural Stem Cell for Spinal Cord Injury Repair.
Liu D, Niu R, Wang S, Shao L, Yang X, Liu X, Ma X, Zhu Z, Zhang J, Shi B, Ni H, Du X
ACS nano 2025 Jan 21;19(2):2591-2614
ACS nano 2025 Jan 21;19(2):2591-2614
BMP6, a potential biomarker of inflammatory fibrosis and promising protective factor for dilated cardiomyopathy.
Jiang F, Tang J, Wei X, Pan H, Fan X, Zhang P, Guo S
Chinese medicine 2025 Jan 15;20(1):12
Chinese medicine 2025 Jan 15;20(1):12
ALKBH5 alleviates lower extremity arteriosclerosis by regulating ITGB1 demethylation and influencing macrophage polarization.
Guan Z, Wang X, Xu C, Lu R
Heliyon 2025 Jan 15;11(1):e41495
Heliyon 2025 Jan 15;11(1):e41495
Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice.
Yang S, Duan H, Zeng J, Yan Z, Niu T, Ma X, Zhang Y, Hu J, Zhang L, Zhao X
Journal of ethnopharmacology 2025 Jan 13;339:119157
Journal of ethnopharmacology 2025 Jan 13;339:119157
YTHDF1-mediated m6A modification of GBP4 promotes M1 macrophage polarization in acute lung injury.
Cao F, Wang S, Tan Q, Hou J, Li Y, Ma W, Zhao S, Gao J
Respiratory research 2025 Jan 13;26(1):11
Respiratory research 2025 Jan 13;26(1):11
IFN-τ Maintains Immune Tolerance by Promoting M2 Macrophage Polarization via Modulation of Bta-miR-30b-5p in Early Uterine Pregnancy in Dairy Cows.
Feng X, Yang C, Wang T, Zhang J, Zhou H, Ma B, Xu M, Deng G
Cells 2025 Jan 10;14(2)
Cells 2025 Jan 10;14(2)
N 6-Methyladenosine Demethylase FTO Controls Macrophage Homeostasis in Diabetic Vasculopathy.
Feng S, Zhang Q, Liu Q, Huang C, Zhang H, Wang F, Zhu Y, Jian Q, Chen X, Jiang Q, Yan B
Diabetes 2025 Jan 1;74(1):82-95
Diabetes 2025 Jan 1;74(1):82-95
Macrophage metabolic reprogramming ameliorates diabetes-induced microvascular dysfunction.
Zhang QY, Zhang HY, Feng SG, Yao MD, Ding JJ, Li XM, Ye R, Liu Q, Yao J, Yan B
Redox biology 2025 Feb;79:103449
Redox biology 2025 Feb;79:103449
The chemokine CX3CL1 promotes intraperitoneal tumour growth despite enhanced T-cell recruitment in ovarian cancer.
Seitz S, Dreyer TF, Stange C, Steiger K, Wohlleber D, Anton M, Pham TA, Sauter-Peschke D, Reuning U, Multhoff G, Weichert W, Kiechle M, Magdolen V, Bronger H
Neoplasia (New York, N.Y.) 2025 Feb;60:101130
Neoplasia (New York, N.Y.) 2025 Feb;60:101130
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Zhang Y, Zhu X, Chen L, Gao T, Chen G, Zhu J, Wang G, Zuo D
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling.
Chen J, Sheng R, Mo Q, Backman LJ, Lu Z, Long Q, Chen Z, Cao Z, Zhang Y, Liu C, Zheng H, Qi Y, Cao M, Rui Y, Zhang W
Bioactive materials 2025 Feb;44:319-338
Bioactive materials 2025 Feb;44:319-338
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection.
Yu Z, Wang Z, Chen Y, Wang Y, Tang L, Xi Y, Lai K, Zhang Q, Li S, Xu D, Tian A, Wu M, Wang Y, Yang G, Gao C, Huang T
Biomaterials 2025 Feb;313:122772
Biomaterials 2025 Feb;313:122772
Dual-sided centripetal microgrooved poly (D,L-lactide-co-caprolactone) disk encased in immune-regulating hydrogels for enhanced bone regeneration.
Wu Y, Yue X, Zhang Y, Yu N, Ge C, Liu R, Duan Z, Gao L, Zang X, Sun X, Zhang D
Materials today. Bio 2025 Feb;30:101436
Materials today. Bio 2025 Feb;30:101436
Hyaluronidase-responsive hydrogel loaded with magnetic nanoparticles combined with external magnetic stimulation for spinal cord injury repair.
Fan Z, Zhang G, Zhan W, Wang J, Wang C, Yue Q, Huang Z, Wang Y
Materials today. Bio 2025 Feb;30:101378
Materials today. Bio 2025 Feb;30:101378
Gelatin methacryloyl hydrogel encapsulating molybdenum-inspired macrophage-derived exosomes accelerates wound healing via immune regulation and angiogenesis.
Deng Y, Xie J, Xiao J, Huang X, Cao Z
International journal of biological macromolecules 2025 Feb;291:138947
International journal of biological macromolecules 2025 Feb;291:138947
The promoting effect of Balanus albicostatus cement protein 19k (Balcp19k) on wound healing by regulating fibroblast migration and relieving early-stage inflammation responses.
Song J, Zeng L, Ye Z, Lu P, Jing C, Hu B, He H
International journal of biological macromolecules 2025 Feb;289:138781
International journal of biological macromolecules 2025 Feb;289:138781
Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain.
Wang W, Wang Y, Huang X, Wu P, Li L, Zhang Y, Chen Y, Chen Z, Li C, Zhou Y, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2405483
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2405483
Effect of 3D-Printed Polycaprolactone Scaffold With Powdery/Smooth Micromorphology on Local Immune Environments.
Hou L, Meng Z, Zhang J, Jiao Y, Chang K, He J, Zhang J
Journal of biomedical materials research. Part A 2025 Feb;113(2):e37869
Journal of biomedical materials research. Part A 2025 Feb;113(2):e37869
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Yang ZC, Lin H, Liu GJ, Pan H, Zhu JL, Zhang XH, Gao F, Wang Z, Wang ZH
Stem cell research & therapy 2025 Feb 7;16(1):52
Stem cell research & therapy 2025 Feb 7;16(1):52
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis.
Xu H, He Y, Chen S, Meng C, Liu Q, Huang XJ, You HB
International immunopharmacology 2025 Feb 6;147:114027
International immunopharmacology 2025 Feb 6;147:114027
Understanding the relationship between silicone implants, tumor antigens, and breast cancer risk: An immunological study in rats.
Zhou Y, Li Z, Wang G, Yu H, Zhou Y, Li Y, Chen W, Dai H, He Y, Li L
International immunopharmacology 2025 Feb 6;147:113991
International immunopharmacology 2025 Feb 6;147:113991
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway.
Dong M, Ma X, Li F
Stem cell research & therapy 2025 Feb 28;16(1):103
Stem cell research & therapy 2025 Feb 28;16(1):103
Exosomes from adipose-derived stem cells accelerate wound healing by increasing the release of IL-33 from macrophages.
Wang Y, Ding H, Bai R, Li Q, Ren B, Lin P, Li C, Chen M, Xu X
Stem cell research & therapy 2025 Feb 21;16(1):80
Stem cell research & therapy 2025 Feb 21;16(1):80
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress.
Liu Y, Yu Y, Chen C, Wu X, Zheng Q, Zhang X, Ye L, Zhang C, Feng Z
International immunopharmacology 2025 Feb 20;148:114117
International immunopharmacology 2025 Feb 20;148:114117
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Zhang Y, Tang Z, Chen L, Yang M, Zeng Y, Bai X, Zhang B, Zhou J, Zhang W, Tang S
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Peptide amphiphiles alleviate myocardial endoplasmic reticulum stress to enhance cardiomyocyte-macrophage communication and promote macrophage M2 polarization.
Guo W, Chen H, Liu F, Chen B, Liu C, Cai Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:719-734
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:719-734
Bulk and Single-cell transcriptomic profiling identifies C1QA as an Immune-Associated hub genes in graves' ophthalmopathy.
Li LN, Zheng ZJ, Wu JM, Li SX, Cai MY, Zou MC
Endocrine 2025 Dec;90(3):1350-1368
Endocrine 2025 Dec;90(3):1350-1368
P4HB regulates tumor-associated macrophage polarization and chemotaxis by enhancing IL-6 cytokine secretion in glioblastoma.
Wang M, Ma Z, Wang X, Wang Z, Wang W, Zhang Z, Li R, Liu X, Pei D
Annals of medicine and surgery (2012) 2025 Dec;87(12):8245-8256
Annals of medicine and surgery (2012) 2025 Dec;87(12):8245-8256
SPP1-mediated crosstalk between macrophage and fibroblasts promotes benign airway stenosis.
Niu F, Sun B, Yu Y, Xu X, Li H, Huang L, Wang Y, Cai Z
Archives of biochemistry and biophysics 2025 Dec;774:110627
Archives of biochemistry and biophysics 2025 Dec;774:110627
Indirubin regulates M1/M2 polarization and inhibits ferroptosis in dextran sulfate sodium induced colitis and in cultured THP-1 cells.
Huang YX, Zhang JR, Fu SH, Liu Z, Zhong HJ, Zhong QY, Luo YD, Hu YJ, Zhu HP, Wen B, Chen S
Pharmaceutical biology 2025 Dec;63(1):698-715
Pharmaceutical biology 2025 Dec;63(1):698-715
PFKFB3-Inhibitor 3PO-Mediated Glycolytic Reprogramming Promotes Inflammatory Dental Pulp Repair: An In Vitro and In Vivo Study.
Zhao Y, Peng Y, Wang D, Zhang L, Qiu Y, Cui J, Xie F, Zhu N, Qin M, Wang Y
International endodontic journal 2025 Dec;58(12):1872-1889
International endodontic journal 2025 Dec;58(12):1872-1889
Exosomal miR-216a-5p targeting TLR-4 alleviates liver ischemia-reperfusion injury by regulating M2 macrophage polarization and neutrophil inflammation.
Liu L, Huang YX, Wang Q, Zhao XH, Liu L, Zhou YJ, Qiao YL, Li SW
Annals of medicine 2025 Dec;57(1):2548385
Annals of medicine 2025 Dec;57(1):2548385
Lactobacillus extracellular vesicle-driven oxygen-releasing photothermal hydrogel reprograms macrophages and promotes angiogenesis to accelerate diabetic wound healing.
Yuan P, Deng M, Li X, Lu X, Yang H, Jin R, Wang L, Chen M, Bai T, Liu T, Zhou W, Wang X
Bioactive materials 2025 Dec;54:144-158
Bioactive materials 2025 Dec;54:144-158
Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization.
Wu X, He T, Yang C, Xue S, Yuan Q, Chen F, Liu J, Li G
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2025 Dec;42(1):2503312
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2025 Dec;42(1):2503312
Synthesis of novel pyrazole derivatives and neuroprotective effect investigation.
Feng A, Zeng Q, Wang J, Li H, Fang X, Geng Y, Pan W, Li G, Dong J
Journal of enzyme inhibition and medicinal chemistry 2025 Dec;40(1):2583820
Journal of enzyme inhibition and medicinal chemistry 2025 Dec;40(1):2583820
Functionalized hydrocaffeic acid-chitosan/EGTA hydrogel rescues mitochondrial dysfunction for immunomodulation and joint repair in rheumatoid arthritis.
Li J, Ni Y, Tao Y, Cai H, Wu A, Zhang F, Meng S, Luo Y, Zhang W, Wang Y
Materials today. Bio 2025 Dec;35:102605
Materials today. Bio 2025 Dec;35:102605
4'-hydroxychalcone nanofiber hydrogel dressing promotes diabetic chronic wound healing by regulating macrophage polarization via the TLR/IL-17/TNF signaling pathway.
Li HY, Li MY, Cui CX, Yu HM, Sun Y, Yang JJ, Li YR, Li YQ, Liu TM
Materials today. Bio 2025 Dec;35:102474
Materials today. Bio 2025 Dec;35:102474
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Li W, Chen J, Yu L, Ding L, Zhang X, Yan L, Shi M
Materials today. Bio 2025 Dec;35:102423
Materials today. Bio 2025 Dec;35:102423
Isoliquiritigenin micellar microneedle for pH monitoring and diabetic wound healing.
Xue H, Zhang C, Lin D, Gu Q, Sun C, Lin X, Zhang C, Lei L, Liu L
Materials today. Bio 2025 Dec;35:102356
Materials today. Bio 2025 Dec;35:102356
ACOD1/Itaconate regulates trophoblast function through the PI3K/Akt/FOLR1 axis to participate in the pathogenesis of recurrent spontaneous abortion.
Feng T, Wu S, Fang J, Ding J, Shen F, Yang J
Biochemical pharmacology 2025 Dec;242(Pt 3):117405
Biochemical pharmacology 2025 Dec;242(Pt 3):117405
Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
Ding Y, Zhang H, Wen H, Zhao S, Li J, Liu X, Wang K, Huang Y, Xu M, Sun D
The American journal of pathology 2025 Dec;195(12):2477-2491
The American journal of pathology 2025 Dec;195(12):2477-2491
A study on the establishment of a traumatic brain injury model of tree shrews and the observation of neuroinflammatory responses.
Yu W, Yang L, Zhang X, Zhang J, Zhang J, Wang L, Huang Y, Hong S, Chen L, Wu H, Li J
IBRO neuroscience reports 2025 Dec;19:912-918
IBRO neuroscience reports 2025 Dec;19:912-918
Z-Ligustilide's antidepressant effects in adolescent depression involve the PTEN-induced putative kinase 1 (PINK1) - protein kinase A (PKA)- Na(+)/Ca(2+) exchanger (NCLX) pathway, facilitating mitochondrial endosymbiosis and promoting mitophagy in microglia.
Yi T, Qiu F, Shi J, Wu D, Li D, Zhang X, He X, Huang D, Tan K, Zeng H, Wang Y, Ge J, Mei Z, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157494
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157494
Viscoelastic Hydrogel with Mechanomodulatory Tension Shielding and Time-Dependent Immunomodulatory Effects for Scarless Healing.
Kuan CH, Wang YN, Liao EF, Wang WH, Kung PJ, Huang WY, Chen SH, Chen SH, Hu JJ, Lin SJ, Wang TW
Advanced healthcare materials 2025 Dec;14(32):e01954
Advanced healthcare materials 2025 Dec;14(32):e01954
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Zhang H, Huang X, Chen R, Lin W, Li L, Peng X, Yang X, Chen X, Guo T, Weng J, Li J, Yuan Q, Tan H, Wang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
EGCG-Loaded Zinc Ion-Cross-Linked Injectable Sodium Alginate Hydrogel for Extraction Socket Healing.
Han Y, Wang C, Liu M, Ma B, Ge S, Yu Y
ACS biomaterials science & engineering 2025 Dec 8;11(12):7313-7328
ACS biomaterials science & engineering 2025 Dec 8;11(12):7313-7328
Autophagy-dependent secretion of ENO1 mediates chemoresistance of glioblastoma and tumor microenvironment remodeling.
Xie Q, Chen L, Huang Y, Yu Z, Zhu R, Li J, Zhao J, Song Y, Li H, Lu Y
Cell death & disease 2025 Dec 6;17(1):79
Cell death & disease 2025 Dec 6;17(1):79
The Role of Chaf1b in Maintaining Glioma Stem Cell Stemness and Regulating Microglial Polarization.
He YL, Niu L, Wang C, Liao ZP, Liu K, Gao S, Du AC, Liu WG, Jia J, Zhang YB, Yin H, Yuan GQ, Pan YW
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Dec 3;45(49)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Dec 3;45(49)
CD146(+) CAFs mediate immunosuppression in gastric cancer via COL4A1: potential therapeutic targets.
Chen J, Xu P, Wang Q, Dai J, Liang S, Yang S, Xie G, Li X, Wang Y, Hua H, Ping X, Shen J, Shen L
Journal for immunotherapy of cancer 2025 Dec 21;13(12)
Journal for immunotherapy of cancer 2025 Dec 21;13(12)
Human urine-derived stem cells alleviate psoriasis by suppressing JAK2/STAT3 pathway-mediated macrophage polarization.
Zhuo YQ, Huang QM, Gu HC, Wang LF, Tula D, Wei XY, Zhang ZH, Deng KY, Xin HB
Stem cell research & therapy 2025 Dec 17;17(1):38
Stem cell research & therapy 2025 Dec 17;17(1):38
Identification and targeting oxidative phosphorylation/glycolysis to overcome anti-CSF-1R therapy resistance in glioblastoma.
Miao C, Ding Z, Wu J, An Q, Shu Y, Jiang H, Gao P, Chen R, Chen XQ
Cell death & disease 2025 Dec 10;17(1):84
Cell death & disease 2025 Dec 10;17(1):84
tsRNA-10105-enriched migrasomes mediate hepatocellular carcinoma immunosuppressive microenvironment by inducing M2 Macrophage polarization.
Pan L, Zhou R, Wen Z, Lin Y, Cai H, Lin C, Xu X, Ruan L, Zeng Y, Zhang H, Zhou Y, Hu X
Experimental cell research 2025 Dec 1;453(2):114729
Experimental cell research 2025 Dec 1;453(2):114729
Scutellarin Modulates Astrocyte-Microglia-Neuron Crosstalk to Mitigate Neuroinflammation and Apoptosis in Cerebral Ischemia.
Chen H, Duan Z, Jia Q, Zhang X, Xu D, Zheng L, Qi Z, Yang Y, Yang L, Wu C
Molecular neurobiology 2025 Aug;62(8):10834-10855
Molecular neurobiology 2025 Aug;62(8):10834-10855
Pathology-inspired collagen-binding thermosensitive micelle drops enable prolonged and efficient treatment of fungal keratitis.
Cai M, Zhong H, Wang X, Li L, Zhou X, Wang Y, Hua X, Guo S, Yuan X
Bioactive materials 2025 Aug;50:396-413
Bioactive materials 2025 Aug;50:396-413
Quorum Sensing Molecule Autoinducer-2 Promotes Macrophage Classical Polarization and Exacerbates Periodontal Inflammation Via Nf-Κb Signalling.
Zhou H, Huang J, Fan Z, Sun W, Xu Y, Li L
Inflammation 2025 Aug;48(4):1974-1986
Inflammation 2025 Aug;48(4):1974-1986
Irisin Alleviates Autoimmune Uveitis Through Promoting Retinal Microglial M1 to M2 Phenotypic Polarization Mediated by HIF-1α Pathway.
Wang M, Huang X, Shu J, Li H, Yang T, Li N, Yang P
Inflammation 2025 Aug;48(4):1716-1727
Inflammation 2025 Aug;48(4):1716-1727
More severe vascular remodeling in deep brain regions caused by hemodynamic differences is a potential mechanism of hypertensive cerebral small vessel disease.
Liu N, Li N, Cao X, Qin W, Huang Q, Xue Y, Zhang M, Zhang Y, Kang S, Chen G, Tang J, Wang S, Fu J
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025 Aug;45(8):1593-1605
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025 Aug;45(8):1593-1605
Rescuing inflammatory microenvironment induced senescence via MgO immune mediated asymmetric short fibers for accelerating diabetic wound repair.
Chen Y, Liu Q, Guan J, Zheng C, Shi S, Zheng W, Guan J, Mao Y
Materials today. Bio 2025 Aug;33:102079
Materials today. Bio 2025 Aug;33:102079
Hyaluronic acid-anchored nanoparticles co-delivering emodin and siRNA confers protection against rheumatoid arthritis via macrophage polarization.
Qin M, Chen P, Chen H, Liu F, He W, Yao E
Materials today. Bio 2025 Aug;33:102074
Materials today. Bio 2025 Aug;33:102074
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
Sun J, Chen QZ, Hong AZ, Ju F, Wang HL, Zhang B, Liu W, Sun YC, Tan J, Yang QQ, Zhou YL
Materials today. Bio 2025 Aug;33:101999
Materials today. Bio 2025 Aug;33:101999
A novel triazole derivative ameliorates ulcerative colitis by targeting PPAR gamma.
Xie C, Yue J, Li Y, Zhang X, An S, Chen J, Tong J, Wang R, Xie Y, Lu M, Chen J, Wang T, Wu L, He W, Chen G, Yu C
International journal of biological macromolecules 2025 Aug;320(Pt 2):145906
International journal of biological macromolecules 2025 Aug;320(Pt 2):145906
Immunoregulatory function and anticancer effects of Polygonatum sibiricum polysaccharides against hepatic carcinoma via macrophage phenotype modulation.
Leng M, Jiang H, Lan H, Zhong W, Shi H, Jia J, Bao Y
International journal of biological macromolecules 2025 Aug;319(Pt 1):145423
International journal of biological macromolecules 2025 Aug;319(Pt 1):145423
IGF2BP1 exacerbates neuroinflammation and cerebral ischemia/reperfusion injury by regulating neuronal ferroptosis and microglial polarization.
Li Y, Jiang J, Zhuo Y, Li J, Li Y, Xia Y, Yu Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167877
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167877
TSPO participates in the pathogenesis of diabetic periodontitis related to mitophagy.
Jin W, Lu D, Wei W, Wang M, Chen R, Yan F, Li Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167866
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167866
Gut Microbiota-Derived Acetate Ameliorates Endometriosis via JAK1/STAT3-Mediated M1 Macrophage Polarisation.
Xu Y, Zhu Y, Wu X, Peng W, Zhong Y, Cai Y, Chen W, Liu L, Tan B, Chen T
Microbial biotechnology 2025 Aug;18(8):e70202
Microbial biotechnology 2025 Aug;18(8):e70202
Modified Fish-Skin-Collagen-Based Hydrogels with Antioxidant and Antibacterial Functions for Diabetic Wound Healing.
Geng X, Li W, Qu J, Wang Q, Che T, Yan L, Cui H, Liu D, Qin S
Advanced healthcare materials 2025 Aug;14(21):e2501456
Advanced healthcare materials 2025 Aug;14(21):e2501456
MDL800, a SIRT6 activator, mitigates neuroinflammation-induced retinal damage by modulating microglial M1/M2 polarization in experimental glaucoma.
Hu F, Zhang D, Wu J
Cellular signalling 2025 Aug;132:111832
Cellular signalling 2025 Aug;132:111832
Intravenous administration of mesenchymal stem cell-derived exosomes mitigates traumatic brain injury by inhibiting neutrophil extracellular trap formation via miR-26a-5p.
Ye Y, Hou X, Sang X, Shi H, Guo Y, Yang C, Chen W, Cai H, Peng C, Li Y, Yu S, Zhang D, Hou L
Neuroreport 2025 Aug 6;36(12):651-668
Neuroreport 2025 Aug 6;36(12):651-668
COG1410 Alleviated Chronic Sleep Deprivation-Induced Memory Loss by Regulating Microglial Phagocytosis and Inhibiting Hippocampal Inflammation.
Wu P, Fu C, Chen M, Wu F, He W, Luo Q, Wang H, Li Y
ACS chemical neuroscience 2025 Aug 6;16(15):2921-2934
ACS chemical neuroscience 2025 Aug 6;16(15):2921-2934
Dihydroartemisinin restrains angiogenesis through the TNF-α pathway to enhance the efficacy of anti-PD-1 immunotherapy in breast cancer.
Zou M, Gong Y, Zeng J, Zhang X, Guo X, Hua J, Chen Z, Lin L, Wu F
Biochemical and biophysical research communications 2025 Aug 30;776:152171
Biochemical and biophysical research communications 2025 Aug 30;776:152171
Kurarinone protects against renal injury and fibrosis after unilateral ureteral obstruction through enhancement of the Nrf-2 signaling pathway.
Dong T, Zhao D, Jiang S, Gu Y, Wang C, Yang Q, Liu T, Liu X
Journal of molecular histology 2025 Aug 29;56(5):286
Journal of molecular histology 2025 Aug 29;56(5):286
Activation of M1 macrophages promotes diabetic kidney disease by modulating glycolysis via HIF-1α-HK2 signaling pathway.
Pei X, Lu L, Huang Z, Wei Y, Li Y, Wang Q, Yang Y, Zhuang L, Jin G
Diabetology & metabolic syndrome 2025 Aug 29;17(1):362
Diabetology & metabolic syndrome 2025 Aug 29;17(1):362
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Xu L, Ma Y, Jiang G, Cao Z, Song J, Gao Y, Wang G, Fan J, Yang Y, Yu X
International immunopharmacology 2025 Aug 28;161:115086
International immunopharmacology 2025 Aug 28;161:115086
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
Cui Z, Gu G, Chen F, Li J, Du X, Chen S, Zhang H, Li C, Shao J, Xi J, Du Y, Zhao Q, Xi Y
Cell death & disease 2025 Aug 27;16(1):651
Cell death & disease 2025 Aug 27;16(1):651
CAF-derived exosomes drive the FGF4/SHH feedback loop by encapsulating GREM1 in non-small cell lung cancer.
Wu X, Chen W, Fang T, Chen Z, Fang S, Zhou C
Molecular medicine (Cambridge, Mass.) 2025 Aug 23;31(1):281
Molecular medicine (Cambridge, Mass.) 2025 Aug 23;31(1):281
Ultrasound-triggered targeted delivery of engineered ADSCs-derived exosomes with high SDF-1α levels to promote cardiac repair following myocardial infarction.
Wang H, Jiang R, Zhong F, Hu Y, Liu J, Chen Y, Su W, Cao S, Zhou Q, Deng Q
International journal of pharmaceutics 2025 Aug 20;681:125786
International journal of pharmaceutics 2025 Aug 20;681:125786
RBM15 enhances paclitaxel resistance in triple-negative breast cancer by targeting m(6)A methylation of TNFSF9 and inducing polarization of tumor-associated macrophages to M2 phenotype.
Fu J, Wei C, Chen Y, He X, Zhang K
Hereditas 2025 Aug 19;162(1):167
Hereditas 2025 Aug 19;162(1):167
Functional anti-inflammatory mesoporous silica nanoplatform for Synergistic and Targeted abdominal aortic aneurysm treatment.
Wu Z, Wu X, Meng X, Lei J, Zeng C, Pu H, Liu Y, Xu Z, Wu X, Huang S, Qin J, Liu J, Lu X, Li B
Journal of colloid and interface science 2025 Apr;683(Pt 1):1040-1054
Journal of colloid and interface science 2025 Apr;683(Pt 1):1040-1054
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Fang M, Lu L, Lou J, Ou J, Yu Q, Tao X, Zhu J, Lin Z
Molecular neurobiology 2025 Apr;62(4):4743-4768
Molecular neurobiology 2025 Apr;62(4):4743-4768
Galvanic Cell Bipolar Microneedle Patches for Reversing Photoaging Wrinkles.
Lin X, Jia Q, Lin X, Shi J, Gong W, Shen K, Liu B, Sun L, Fan Z
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(16):e2500552
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(16):e2500552
An injectable and adaptable system for the sustained release of hydrogen sulfide for targeted diabetic wound therapy by improving the microenvironment of inflammation regulation and angiogenesis.
Zhang H, Dong X, Liu Y, Duan P, Liu C, Liu K, Yu Y, Liang X, Dai H, Yu A
Acta biomaterialia 2025 Apr;196:364-379
Acta biomaterialia 2025 Apr;196:364-379
Activation of aryl hydrocarbon receptor attenuates intestinal inflammation by enhancing IRF4-mediated macrophage M2 polarization.
Li J, Wang L, Wang M, Zhang H
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167735
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167735
Glioblastoma- derived exosomes (GBM-Exo) regulate microglial M2 polarization via the RAC1/AKT/NRF2 pathway.
Wu Q, Chen S, Xie X, Yan H, Feng X, Su G, Zhang Z
Journal of neuro-oncology 2025 Apr;172(2):447-460
Journal of neuro-oncology 2025 Apr;172(2):447-460
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.
Liu Y, Yao C, Sheng B, Zhi S, Chen X, Ding P, Zhang J, Tao Z, Li W, Zhuang Z, Mao J, Peng Z, Yan H, Jin W
Translational stroke research 2025 Apr;16(2):448-466
Translational stroke research 2025 Apr;16(2):448-466
Prevascularized Hydrogel Enhancing Innervation and Repair of Full-Thickness Volumetric Muscle Loss in Abdominal Wall Defects.
Hsieh CC, Dai JZ, Ni CC, Wei SY, Tsai MC, Chen PY, Fang L, Xie RH, Chen GY, Yin GC, Chen YC
Advanced healthcare materials 2025 Apr;14(11):e2402433
Advanced healthcare materials 2025 Apr;14(11):e2402433
The Phase-Transited Lysozyme Coating Modified Small Intestinal Submucosa Membrane Loaded with Calcium and Zinc Ions for Enhanced Bone Regeneration.
Yang Y, Tong T, Li X, Zheng H, Yao S, Deng J, Zhang Q, Liu Z, Huang X, Li H, Mu Y, Ma S
Advanced healthcare materials 2025 Apr;14(10):e2404564
Advanced healthcare materials 2025 Apr;14(10):e2404564
Mannose-Glycated Metal-Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy.
Tan X, Sheng R, Li W, Tao Y, Liu Z, Yang N, Hashmi SS, Feng F, Liu F, Ge L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2415565
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2415565
CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-Associated Macrophages.
Xiong J, Huang J, Xu H, Wu Q, Zhao J, Chen Y, Fan G, Guan H, Xiao R, He Z, Wu S, Ouyang W, Wang S, Zhang L, Xia P, Zhang W, Wu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2412881
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2412881
Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.
Lei D, Liao L, Qin T, Guan X, Duan K, Gao Z, Jin W, Yin M, Zhang K, Liu Y, Chen Y, Gao H, Li J, Huang F, Liu W, Xia C, Wang B, Huang H, Lv S, Zhi Q, Huang J, Gao M, Lu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413697
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413697
A poly(ether-ketone-ketone) composite scaffold simulating the immune-osteogenic cascade for in situ bone regeneration.
Yang Q, Wang S, Chen A, Zhao M, Zhang X, Sheng L, Zhang C, Wu Z
Journal of materials chemistry. B 2025 Apr 9;13(15):4641-4656
Journal of materials chemistry. B 2025 Apr 9;13(15):4641-4656
Multi-Omics Analysis of the Immune Effect of the Engineered Exosome Drug Delivery System in Inducing Macrophage Apoptosis.
Xiang W, Zhu Z, Shang Q, Yasin P, Wu Y, Song X
Pharmaceutics 2025 Apr 8;17(4)
Pharmaceutics 2025 Apr 8;17(4)
Platycodon grandiflorum exosome-like nanoparticles: the material basis of fresh platycodon grandiflorum optimality and its mechanism in regulating acute lung injury.
Fu J, Liu Z, Feng Z, Huang J, Shi J, Wang K, Jiang X, Yang J, Ning Y, Lu F, Li L
Journal of nanobiotechnology 2025 Apr 4;23(1):270
Journal of nanobiotechnology 2025 Apr 4;23(1):270
Silybin attenuates microglia-mediated neuroinflammation via inhibition of STING in experimental subarachnoid hemorrhage.
Cui Y, Zhi SM, Ding PF, Zhu T, Chen XX, Liu XZ, Sheng B, Li XJ, Wang J, Zhang JT, Xu MX, Jiang YX, Hang CH, Li W
International immunopharmacology 2025 Apr 4;151:114305
International immunopharmacology 2025 Apr 4;151:114305
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
Su S, Wang R, Bai J, Gao S, Zhou R, Zhou F
RSC advances 2025 Apr 28;15(18):13857-13873
RSC advances 2025 Apr 28;15(18):13857-13873
TIPE3 promotes drug resistance in colorectal cancer by enhancing autophagy via the USP19/Beclin1 pathway.
Chen C, Jin L, Wan H, Liu H, Zhang S, Shen G, Gong J, Zhu Y
Cell death discovery 2025 Apr 25;11(1):202
Cell death discovery 2025 Apr 25;11(1):202
Formononetin ameliorates depression-like behaviors through rebalancing microglia M1/M2 polarization and inhibiting NLRP3 inflammasome: involvement of activating PPARα-mediated autophagy.
Peng S, Su P, Liu L, Li Z, Liu Y, Tian L, Bai M, Xu E, Li Y
Molecular medicine (Cambridge, Mass.) 2025 Apr 24;31(1):153
Molecular medicine (Cambridge, Mass.) 2025 Apr 24;31(1):153
Lactiplantibacillus plantarum -derived extracellular vesicles alleviate acute lung injury by inhibiting ferroptosis of macrophages.
Zhao Q, Lai J, Jiang Y, Cui E, Chang H, Pan R, Li P, Shao JZ, Zheng J, Chen Y
Journal of nanobiotechnology 2025 Apr 23;23(1):307
Journal of nanobiotechnology 2025 Apr 23;23(1):307
Facile Nanocomposite Hydrogel Scaffold with Sustained Drug Release and Osteo-Immunomodulatory Effects to Enhance Bone Regeneration.
Zhao F, Su Y, Liu H, Zhao Y, Zhang L, Zhuge N, Zhao P, Ning Z, Kang Q, Liu D
ACS applied materials & interfaces 2025 Apr 2;17(13):19286-19303
ACS applied materials & interfaces 2025 Apr 2;17(13):19286-19303
The E3 ligase c-Cbl modulates microglial phenotypes and contributes to Parkinson's disease pathology.
Deng S, Zhang Z, Liu L, Xu C, Zhang D, Dong L, Gao C, Wang X, Fan Z
Cell death discovery 2025 Apr 17;11(1):184
Cell death discovery 2025 Apr 17;11(1):184
Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8(+)T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice.
Fan Z, Yi Z, Li S, He J
BMC biotechnology 2025 Apr 16;25(1):30
BMC biotechnology 2025 Apr 16;25(1):30
Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity.
Zhou X, Zhu D, Wu D, Li G, Liang H, Zhang W, Wu Y, Xu H, Zhang Z, Tong B, Song Y, Wang K, Feng X, Lei J, Wang H, Zhang X, Ma L, Chen Y, Wei J, Ou Z, Peng S, Wu X, Tan L, Wang B, Yang C
Cell reports. Medicine 2025 Apr 15;6(4):102079
Cell reports. Medicine 2025 Apr 15;6(4):102079
pH-responsive and self-adaptive injectable sodium alginate/carboxymethyl chitosan hydrogel accelerates infected wound healing by bacteriostasis and immunomodulation.
Zhang X, Liu Y, Wang Z, Zhao H, Zhan L, Gui H, Xu X, Ma X, Ma B
Carbohydrate polymers 2025 Apr 15;354:123322
Carbohydrate polymers 2025 Apr 15;354:123322
Inflammatory Microenvironment-Modulated Conductive Hydrogel Promotes Vascularized Bone Regeneration in Infected Bone Defects.
Yang Q, Wu T, Wu X, Ren M, Liu F, Yang S
ACS biomaterials science & engineering 2025 Apr 14;11(4):2353-2366
ACS biomaterials science & engineering 2025 Apr 14;11(4):2353-2366
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
He J, Yue H, Zhang S, Dong R, Zhang F, Wang X, Wang K, Zhang H, Yang D, Dong Z, Liu H
Respiratory research 2025 Apr 12;26(1):136
Respiratory research 2025 Apr 12;26(1):136
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Fu H, Wang Y, Huang B, Liang Z, Li Y, Cao Z, Wu J, Zhao Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
3D mesenchymal stem cell exosome-functionalized hydrogels for corneal wound healing.
Xu Y, Wei C, Ma L, Zhao L, Li D, Lin Y, Zhou Q, Xie L, Wang F
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:630-646
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:630-646
A novel TLR4 accessory molecule drives hepatic oncogenesis through tumor-associated macrophages.
Kim D, Allen CA, Chung D, Meng L, Zhang X, Zhang W, Ouyang Y, Li Z, Hong F
Cancer letters 2025 Apr 1;614:217543
Cancer letters 2025 Apr 1;614:217543
Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion.
Smith TA, Zhou L, Ghergherehchi CL, Mikesh M, Yang CZ, Tucker HO, Allgood J, Bushman JS, Bittner GD
Neural regeneration research 2025 Apr 1;20(4):1192-1206
Neural regeneration research 2025 Apr 1;20(4):1192-1206
Bifunctional TRPV1 Targeted Magnetothermal Switch to Attenuate Osteoarthritis Progression.
Lv Z, Wang P, Li W, Xie Y, Sun W, Jin X, Jiang R, Fei Y, Liu Y, Shi T, Guo H, Sun Z, Lin J, Wang X, Tan G, Wu Y, Bao N, Shi D
Research (Washington, D.C.) 2024;7:0316
Research (Washington, D.C.) 2024;7:0316
SNORA5A regulates tumor-associated macrophage M1/M2 phenotypes via TRAF3IP3 in breast cancer.
Zhang Y, Zheng A, Shi Y, Lu H
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13809
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13809
Hollow Bismuth Nanoparticle-Loaded Gelatin Hydrogel Regulates M2 Polarization of Macrophages to Promote Infected Wound Healing.
Lv D, Xu Z, Yang H, Rong Y, Zhao Z, Hu Z, Yin R, Guo R, Cao X, Tang B
Biomaterials research 2024;28:0105
Biomaterials research 2024;28:0105
The role and mechanism of macrophage autophagy in the experimental model of chronic obstructive pulmonary disease.
Zhang L, Cheng T, Liu C, He S, Lu J
Tobacco induced diseases 2024;22
Tobacco induced diseases 2024;22
Transglutaminase 2 inhibition ameliorates cardiac fibrosis in myocardial infarction by inducing M2 macrophage polarization in vitro and in vivo.
Maimaitijiang A, Huang Q, Wu Y, Sun S, Chen Q
CytoJournal 2024;21:58
CytoJournal 2024;21:58
Conditioned Medium Derived From Human Dental Follicle Mesenchymal Stem Cells Alleviates Macrophage Proinflammatory Responses Through MAPK-ERK-EGR1 Axis.
Zhang C, Lv P, Liang Q, Zhou J, Wu B, Xu W
Stem cells international 2024;2024:5514771
Stem cells international 2024;2024:5514771
Optogenetic Stimulation of the Cardiac Vagus Nerve to Promote Heart Regenerative Repair after Myocardial Infarction.
Han Y, Wei X, Chen G, Shao E, Zhou Y, Li Y, Xiao Z, Shi X, Zheng H, Huang S, Chen Y, Wang Y, Zhang Y, Liao Y, Liao W, Bin J, Wang Y, Li X
International journal of biological sciences 2024;20(6):2072-2091
International journal of biological sciences 2024;20(6):2072-2091
Breast cancer-derived CAV1 promotes lung metastasis by regulating integrin α6β4 and the recruitment and polarization of tumor-associated neutrophils.
Lin Q, Zong S, Wang Y, Zhou Y, Wang K, Shi F, Wang J, Feng M, Luo W, Zhang L, Lin H, Xiong L
International journal of biological sciences 2024;20(14):5695-5714
International journal of biological sciences 2024;20(14):5695-5714
Nerve growth factor promote VCAM-1-dependent monocyte adhesion and M2 polarization in osteosarcoma microenvironment: Implications for larotrectinib therapy.
Lin SL, Yang SY, Tsai CH, Fong YC, Chen WL, Liu JF, Lin CY, Tang CH
International journal of biological sciences 2024;20(11):4114-4127
International journal of biological sciences 2024;20(11):4114-4127
Magnesium Ion-Doped Mesoporous Bioactive Glasses Loaded with Gallic Acid Against Myocardial Ischemia/Reperfusion Injury by Affecting the Biological Functions of Multiple Cells.
Yu W, Ding J, Chen J, Jiang Y, Zhao J, Liu J, Zhou J, Liu J
International journal of nanomedicine 2024;19:347-366
International journal of nanomedicine 2024;19:347-366
Sphingosine Kinase 1 Aggravates Liver Fibrosis by Mediating Macrophage Recruitment and Polarization.
Ding X, Zhang X, Cao J, Chen S, Chen Y, Yuan K, Chen B, Yang G, Li S, Yang J, Wang G, Tacke F, Lan T
Cellular and molecular gastroenterology and hepatology 2024;18(6):101406
Cellular and molecular gastroenterology and hepatology 2024;18(6):101406
(+)-Borneol inhibits neuroinflammation and M1 phenotype polarization of microglia in epileptogenesis through the TLR4-NFκB signaling pathway.
Li S, Adamu A, Ye Y, Gao F, Mi R, Xue G, Wang Z
Frontiers in neuroscience 2024;18:1497102
Frontiers in neuroscience 2024;18:1497102
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
He J, Tang MY, Liu LX, Kong CX, Chen W, Wang L, Zhi SB, Sun HW, Huang YC, Chen GY, Xin HB, Deng KY
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.
Li Z, Xu P, Deng Y, Duan R, Peng Q, Wang S, Xu Z, Hong Y, Zhang Y
Journal of inflammation research 2024;17:9285-9305
Journal of inflammation research 2024;17:9285-9305
Pretreated MSCs with IronQ Transplantation Attenuate Microglia Neuroinflammation via the cGAS-STING Signaling Pathway.
Yang G, Kantapan J, Mazhar M, Hu Q, Bai X, Zou Y, Wang H, Yang S, Wang L, Dechsupa N
Journal of inflammation research 2024;17:1643-1658
Journal of inflammation research 2024;17:1643-1658
The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression.
Ni Q, Yang H, Rao H, Zhang L, Xiong M, Han X, Deng B, Wang L, Chen J, Shi Y
Frontiers in immunology 2024;15:1522181
Frontiers in immunology 2024;15:1522181
Songorine modulates macrophage polarization and metabolic reprogramming to alleviate inflammation in osteoarthritis.
He XX, Huang YJ, Hu CL, Xu QQ, Wei QJ
Frontiers in immunology 2024;15:1344949
Frontiers in immunology 2024;15:1344949
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Sun Y, Wu J, Zhou L, Wang W, Wang H, Sun S, Xu Y, Zhang L, Jiang X, Zhu G, Xi K, Gu Y, Chen L
Frontiers in bioengineering and biotechnology 2024;12:1415527
Frontiers in bioengineering and biotechnology 2024;12:1415527
In situ MgO nanoparticle-doped Janus electrospun dressing against bacterial invasion and immune imbalance for irregular wound healing.
Zhou T, Chen Y, Fu L, Wang S, Ding H, Bai Q, Guan J, Mao Y
Regenerative biomaterials 2024;11:rbae107
Regenerative biomaterials 2024;11:rbae107
Spatiotemporal evolutionary process of osteosarcoma immune microenvironment remodeling and C1QBP-driven drug resistance deciphered through single-cell multi-dimensional analysis.
Wu X, Tang N, Zhao Q, Xiong J
Bioengineering & translational medicine 2024 Sep;9(5):e10654
Bioengineering & translational medicine 2024 Sep;9(5):e10654
Tangeretin alleviates inflammation and oxidative response induced by spinal cord injury by activating the Sesn2/Keap1/Nrf2 pathway.
Peng B, Hu J, Sun Y, Huang Y, Peng Q, Zhao W, Xu W, Zhu L
Phytotherapy research : PTR 2024 Sep;38(9):4555-4569
Phytotherapy research : PTR 2024 Sep;38(9):4555-4569
Targeted delivery of berberine using bionic nanomaterials for Atherosclerosis therapy.
Wu H, Zhang L, Dong X, Yang J, Zheng L, Li L, Liu X, Jin M, Zhang P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117135
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117135
5-aminolevulinic acid photodynamic therapy for chronic wound infection in rats with diabetes.
Guo N, Chen J, Kong F, Gao Y, Bian J, Liu T, Hong G, Zhao Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117132
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117132
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Wu X, Xia Y, Dai H, Hong C, Zhao Y, Wei W, Zheng D
Advanced healthcare materials 2024 Sep;13(22):e2400770
Advanced healthcare materials 2024 Sep;13(22):e2400770
Tumoral EIF4EBP1 regulates the crosstalk between tumor-associated macrophages and tumor cells in MRTK.
Wu X, Mi T, Jin L, Ren C, Wang J, Zhang Z, Liu J, Wang Z, Guo P, He D
European journal of pharmacology 2024 Sep 5;978:176787
European journal of pharmacology 2024 Sep 5;978:176787
Nobiletin alleviates macrophage M2 polarization by activating AMPK-mTOR-mediated autophagy in pulmonary fibrosis mice.
Cheng Y, Mei X, Shao W, Zheng J, Yin X, Zhang Q, Li J, Zhao P
International immunopharmacology 2024 Sep 30;139:112792
International immunopharmacology 2024 Sep 30;139:112792
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
Liu W, Zhong X, Yi Y, Xie L, Zhou W, Cao W, Chen L
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis.
Wang L, Fan Z, Wang H, Xiang S
European journal of histochemistry : EJH 2024 Sep 17;68(3)
European journal of histochemistry : EJH 2024 Sep 17;68(3)
Anti-colorectal cancer activity of mannatide from spent brewer's yeast by regulating immune cells and immune function in the tumor microenvironment.
Li F, Sun X, Gao X, Zhao S, Tavakoli S, Du Z, Wei Y
International journal of biological macromolecules 2024 Sep 11;280(Pt 1):135531
International journal of biological macromolecules 2024 Sep 11;280(Pt 1):135531
Hypoxic microenvironment promotes diabetic wound healing by polarizing macrophages to the M2 phenotype in vivo.
Cai F, Wang P, Yuan M, Chen W, Liu Y
Journal of molecular histology 2024 Oct;55(5):967-976
Journal of molecular histology 2024 Oct;55(5):967-976
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis.
Huang Y, Cao D, Zhang M, Yang Y, Niu G, Tang L, Shen Z, Zhang Z, Bai Y, Min D, He A
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1715-1733
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1715-1733
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease.
Peng P, Feng T, Yang X, Ding R, Wang J, Chen P, Guo Y, Li P
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:538-549
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:538-549
Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma.
Liang Y, He S, Liu Q, Liu T, Tan Y, Peng T, Huang C, Lu X, Zheng S
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
Novel Collagen Analogs with Multicopy Mucin-Type Sequences for Multifunctional Enhancement Properties Using SUMO Fusion Tags.
Zhao Z, Yuwen W, Duan Z, Zhu C, Fan D
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22173-22185
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22173-22185
Bioactivity-Oriented Separation of "Pepper Alkaloids" from Piper sintenense Hatusima with Potential Antigouty Arthritis Activity.
Yao Z, Li T, Jin M, Fang S, Wang J, Zheng J, Pan K, Zhang J, Zhao G, Yin Z, Huang Y
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23979-23990
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23979-23990
Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment.
Wu T, Wu S, Gao H, Liu H, Feng J, Yin G
European journal of histochemistry : EJH 2024 Oct 23;68(4)
European journal of histochemistry : EJH 2024 Oct 23;68(4)
A hydrogen generator composed of poly (lactic-co-glycolic acid) nanofibre membrane loaded iron nanoparticles for infectious diabetic wound repair.
Zhang X, Yu W, Zhang Y, Zhang W, Wang J, Gu M, Cheng S, Ren G, Zhao B, Yuan WE
Journal of colloid and interface science 2024 Oct 15;672:266-278
Journal of colloid and interface science 2024 Oct 15;672:266-278
Chronic exposure to polystyrene microplastics induced LHR reduction and decreased testosterone levels through NF-κB pathway.
Jin H, Ding J, Liu H, Yang L, Li D, Han X
Environmental pollution (Barking, Essex : 1987) 2024 Oct 1;358:124543
Environmental pollution (Barking, Essex : 1987) 2024 Oct 1;358:124543
M2 Macrophage Polarization and Tissue Remodeling in Autologous Fat Grafting for Diabetic Skin Defects.
Wang Y, Guo X, Zeng H, Chen Z, Yue Y, Jin X
The Journal of craniofacial surgery 2024 Oct 1;35(7):2194-2199
The Journal of craniofacial surgery 2024 Oct 1;35(7):2194-2199
Synergistic rheumatoid arthritis therapy by interrupting the detrimental feedback loop to orchestrate hypoxia M1 macrophage polarization using an enzyme-catalyzed nanoplatform.
Guo D, Liu H, Zhao S, Lu X, Wan H, Zhao Y, Liang X, Zhang A, Wu M, Xiao Z, Hu N, Li Z, Xie D
Bioactive materials 2024 Nov;41:221-238
Bioactive materials 2024 Nov;41:221-238
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Fang M, Yu Q, Ou J, Lou J, Zhu J, Lin Z
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
A polysaccharide from Periplaneta americana promotes macrophage M2 polarization, exhibiting anti-inflammatory and wound-healing activities.
Xiao X, Zhu A, He G, Tokula S, Yang Y, Qing Y, Liu Y, Hu H, Song Q
International journal of biological macromolecules 2024 Nov;281(Pt 1):135836
International journal of biological macromolecules 2024 Nov;281(Pt 1):135836
Esculetin rebalances M1/M2 macrophage polarization to treat sepsis-induced acute lung injury through regulating metabolic reprogramming.
Chen F, Wang N, Liao J, Jin M, Qu F, Wang C, Lin M, Cui H, Wen W, Chen F
Journal of cellular and molecular medicine 2024 Nov;28(21):e70178
Journal of cellular and molecular medicine 2024 Nov;28(21):e70178
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.
Zhang M, Ye Y, Chen Z, Wu X, Chen Y, Zhao P, Zhao M, Zheng C
Acta biomaterialia 2024 Nov;189:505-518
Acta biomaterialia 2024 Nov;189:505-518
Dual-targeted halofuginone hydrobromide nanocomplexes for promotion of macrophage repolarization and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes in adjuvant-induced arthritis in rats.
Zhu J, Lin Y, Li G, He Y, Su Z, Tang Y, Zhang Y, Xu Q, Yao Z, Zhou H, Liu B, Cai X
Journal of pharmaceutical analysis 2024 Nov;14(11):100981
Journal of pharmaceutical analysis 2024 Nov;14(11):100981
Leukocyte Platelet-Rich Plasma-Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization.
Li X, Guo F, Deng J, Li J, Zhang J, Fu M, Fan H
Immunity, inflammation and disease 2024 Nov;12(11):e70064
Immunity, inflammation and disease 2024 Nov;12(11):e70064
An Engineered Hierarchical Hydrogel with Immune Responsiveness and Targeted Mitochondrial Transfer to Augmented Bone Regeneration.
Cai W, Mao S, Wang Y, Gao B, Zhao J, Li Y, Chen Y, Zhang D, Yang J, Yang G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2406287
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2406287
Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway.
Lin Y, Huang Y, Zheng Y, Chen W, Zhang Y, Yang Y, Huang W
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Nov-Dec 01;47(9):369-377
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Nov-Dec 01;47(9):369-377
MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition.
Tong F, Wang Y, Xu Y, Zhou Y, He S, Du Y, Yang W, Lei T, Song Y, Gong T, Gao H
Nature communications 2024 Nov 29;15(1):10382
Nature communications 2024 Nov 29;15(1):10382
Target-Engineered Liposomes Decorated with Nanozymes Alleviate Liver Fibrosis by Remodeling the Liver Microenvironment.
Yang D, Liu K, Cai C, Xi J, Yan C, Peng Z, Wang Y, Jing L, Zhang Y, Xie F, Li X
ACS applied materials & interfaces 2024 Nov 27;16(47):64536-64553
ACS applied materials & interfaces 2024 Nov 27;16(47):64536-64553
Establishment of an Immortalized Porcine Alveolar Macrophage Cell Line That Supports Efficient Replication of Porcine Reproductive and Respiratory Syndrome Viruses.
Diep NV, Hayakawa-Sugaya Y, Ishikawa S, Kawaguchi H, Suda Y, Esaki M, Okuya K, Ozawa M
Pathogens (Basel, Switzerland) 2024 Nov 21;13(12)
Pathogens (Basel, Switzerland) 2024 Nov 21;13(12)
Adipose stem cell exosomes, stimulated by pro-inflammatory factors, enhance immune evasion in triple-negative breast cancer by modulating the HDAC6/STAT3/PD-L1 pathway through the transporter UCHL1.
Zhu Q, Zhang K, Cao Y, Hu Y
Cancer cell international 2024 Nov 20;24(1):385
Cancer cell international 2024 Nov 20;24(1):385
Macrophage erythropoietin signaling promotes macrophage-myofibroblast transformation and fibroblast-myofibroblast differentiation.
Wu P, Zhang W, Guan H, Jin T, Jia J, Luo B, Wang G, Zhang Z
Biochemical and biophysical research communications 2024 Nov 19;734:150783
Biochemical and biophysical research communications 2024 Nov 19;734:150783
Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing.
Su W, Ling Y, Yang X, Wu Y, Xing C
Journal of translational medicine 2024 Nov 18;22(1):1037
Journal of translational medicine 2024 Nov 18;22(1):1037
Astragaloside IV promotes cerebral tissue restoration through activating AMPK- mediated microglia polarization in ischemic stroke rats.
Li MC, Jia JT, Wang YX, Zhuang YM, Wang HY, Lin ZY, Lu Y, Li MZ, Wang ZJ, Zhao H
Journal of ethnopharmacology 2024 Nov 15;334:118532
Journal of ethnopharmacology 2024 Nov 15;334:118532
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Yang W, Zhang X, Wang Z, Zheng X, Wu W, Chen Q
International immunopharmacology 2024 Nov 15;141:112883
International immunopharmacology 2024 Nov 15;141:112883
Exosome-derived circ-001422 promotes tumor-associated macrophage M2 polarization to accelerate the progression of glioma.
Cao W, Zeng Z, Sun J, Chen Y, Kuang F, Luo S, Lan J, Lei S
Communications biology 2024 Nov 13;7(1):1504
Communications biology 2024 Nov 13;7(1):1504
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Lu S, Jin H, Nong T, Li D, Long K, Chen Y, Li Y, Xing H, Pan T, He S, Jiang K, Zhong F
Free radical biology & medicine 2024 Nov 1;224:506-520
Free radical biology & medicine 2024 Nov 1;224:506-520
Gastrodin Regulates PI3K/AKT-Sirt3 Signaling Pathway and Proinflammatory Mediators in Activated Microglia.
Zuo HJ, Wang PX, Ren XQ, Shi HL, Shi JS, Guo T, Wan C, Li JJ
Molecular neurobiology 2024 May;61(5):2728-2744
Molecular neurobiology 2024 May;61(5):2728-2744
Versatile dopamine-functionalized hyaluronic acid-recombinant human collagen hydrogel promoting diabetic wound healing via inflammation control and vascularization tissue regeneration.
Wang Y, Zhang Y, Yang YP, Jin MY, Huang S, Zhuang ZM, Zhang T, Cao LL, Lin XY, Chen J, Du YZ, Chen J, Tan WQ
Bioactive materials 2024 May;35:330-345
Bioactive materials 2024 May;35:330-345
Highly active probiotic hydrogels matrixed on bacterial EPS accelerate wound healing via maintaining stable skin microbiota and reducing inflammation.
Xu H, Li Y, Song J, Zhou L, Wu K, Lu X, Zhai X, Wan Z, Gao J
Bioactive materials 2024 May;35:31-44
Bioactive materials 2024 May;35:31-44
Analysis of the effects of M2 macrophage-derived PDE4C on the prognosis, metastasis and immunotherapy benefit of osteosarcoma.
Pan F, Pan R, Hu R, Zhang H, Lei S, Zhang L, Zhou C, Zeng Z, Tian X, Xie Q
Journal of cellular and molecular medicine 2024 May;28(10):e18395
Journal of cellular and molecular medicine 2024 May;28(10):e18395
MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.
Li X, Ji R, Duan L, Hao Z, Su Y, Wang H, Guan F, Ma S
International journal of biological macromolecules 2024 May;267(Pt 2):131520
International journal of biological macromolecules 2024 May;267(Pt 2):131520
Combining antibiotic-loaded bone cement-based free vastus lateralis muscle-sparing flap with split-thickness skin grafts: A reliable strategy for reconstructing diabetic foot ulcers at non-weight-bearing areas.
Chang S, Jian Y, Liu C, Dal Prà I, Armato U, Chen X, Zhou J, Chen W, Zhang F, Nie K, De Santis D, Deng C, Wei Z
International wound journal 2024 May;21(5):e14900
International wound journal 2024 May;21(5):e14900
Ultrasmall Nanoparticles Regulate Immune Microenvironment by Activating IL-33/ST2 to Alleviate Renal Ischemia-Reperfusion Injury.
Xu L, Xing Z, Yuan J, Han Y, Jiang Z, Han M, Hou X, Xing W, Li Z
Advanced healthcare materials 2024 May;13(13):e2303276
Advanced healthcare materials 2024 May;13(13):e2303276
Turmeric-Derived Nanoparticles Functionalized Aerogel Regulates Multicellular Networks to Promote Diabetic Wound Healing.
Wu B, Pan W, Luo S, Luo X, Zhao Y, Xiu Q, Zhong M, Wang Z, Liao T, Li N, Liu C, Nie C, Yi G, Lin S, Zou M, Li B, Zheng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307630
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307630
Modulation of Cerebrospinal Fluid Dysregulation via a SPAK and OSR1 Targeted Framework Nucleic Acid in Hydrocephalus.
Wang Q, Cheng J, Liu F, Zhu J, Li Y, Zhao Y, Li X, Zhang H, Ju Y, Ma L, Hui X, Lin Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2306622
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2306622
Macrophage-derived ectosomal miR-350-3p promotes osteoarthritis progression through downregulating chondrocyte H3K36 methyltransferase NSD1.
Lin R, Yin J, Huang J, Zou L, Liu L, Tang W, Zhang H, Yang L, Zhang Y, Li G, Wang G, Cai D, Zhang H, Liu Y, Shao Y
Cell death discovery 2024 May 8;10(1):223
Cell death discovery 2024 May 8;10(1):223
Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma.
Wu X, Mi T, Jin L, Ren C, Wang J, Zhang Z, Liu J, Wang Z, Guo P, He D
Cancer immunology, immunotherapy : CII 2024 May 7;73(7):122
Cancer immunology, immunotherapy : CII 2024 May 7;73(7):122
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.
Wu W, Jia H, Chen S, Ma X, Zhou S, Qiu L, Wu X, Li P, Chu H, Zhang G
Molecular medicine (Cambridge, Mass.) 2024 May 31;30(1):72
Molecular medicine (Cambridge, Mass.) 2024 May 31;30(1):72
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Dong M, Zhang X, Peng P, Chen Z, Zhang Y, Wan L, Xiang W, Liu G, Guo Y, Xiao Q, Wang B, Guo D, Zhu M, Yu X, Wan F
Cancer letters 2024 May 28;590:216801
Cancer letters 2024 May 28;590:216801
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, Zeng Y, Chen X, Lv G, Han Z, Zhou D, Zhou D, Yang Y, Zhou A
Cell reports. Medicine 2024 May 21;5(5):101533
Cell reports. Medicine 2024 May 21;5(5):101533
The novel vaccines targeting interleukin-1 receptor type I.
Zhou Y, Huang J, Mai W, Kuang W, Li X, Shi D, Yang Y, Wu J, Wu Z, Liao Y, Zhou Z, Qiu Z
International immunopharmacology 2024 May 10;132:111941
International immunopharmacology 2024 May 10;132:111941
Photothermal and Photocatalytic Glycol Chitosan and Polydopamine-Grafted Oxygen Vacancy Bismuth Oxyiodide (BiO(1-x) I) Nanoparticles for the Diagnosis and Targeted Therapy of Diabetic Wounds.
Kong J, Ma S, Chu R, Liu J, Yu H, Mao M, Ge X, Sun Y, Wang Y
Advanced materials (Deerfield Beach, Fla.) 2024 Mar;36(11):e2307695
Advanced materials (Deerfield Beach, Fla.) 2024 Mar;36(11):e2307695
Arctium lappa L. polysaccharides enhanced the therapeutic effects of nasal ectomesenchymal stem cells against liver fibrosis by inhibiting the Wnt/β-catenin pathway.
Xiang W, Yin G, Liu H, Wei J, Yu X, Xie Y, Zhang L, XueTang, Jiang W, Lu N
International journal of biological macromolecules 2024 Mar;261(Pt 1):129670
International journal of biological macromolecules 2024 Mar;261(Pt 1):129670
A multifunctional composite nanoparticle with antibacterial activities, anti-inflammatory, and angiogenesis for diabetic wound healing.
Li X, Qu S, Ouyang Q, Qin F, Guo J, Qin M, Zhang J
International journal of biological macromolecules 2024 Mar;260(Pt 2):129531
International journal of biological macromolecules 2024 Mar;260(Pt 2):129531
Hydrogen exerts neuroprotective effects after subarachnoid hemorrhage by attenuating neuronal ferroptosis and inhibiting neuroinflammation.
Peng Z, Li XJ, Zhou Y, Zhang JT, Zhu Q, Sun JQ, Hang CH, Li W, Zhang QR, Zhuang Z
Free radical biology & medicine 2024 Mar;215:79-93
Free radical biology & medicine 2024 Mar;215:79-93
A Biomimetic Se-nHA/PC Composite Microsphere with Synergistic Immunomodulatory and Osteogenic Ability to Activate Bone Regeneration in Periodontitis.
Ming P, Liu Y, Yu P, Jiang X, Yuan L, Cai S, Rao P, Cai R, Lan X, Tao G, Xiao J
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2305490
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2305490
Biomimetic "Gemini nanoimmunoregulators" orchestrated for boosted photoimmunotherapy by spatiotemporally modulating PD-L1 and tumor-associated macrophages.
Huang H, Li N, Wei X, Li Q, Guo J, Yang G, Yang H, Cai L, Liu Y, Wu C
Acta pharmaceutica Sinica. B 2024 Mar;14(3):1345-1361
Acta pharmaceutica Sinica. B 2024 Mar;14(3):1345-1361
Wireless Electric Cues Mediate Autologous DPSC-Loaded Conductive Hydrogel Microspheres to Engineer the Immuno-Angiogenic Niche for Homologous Maxillofacial Bone Regeneration.
Sun J, Xu C, Wo K, Wang Y, Zhang J, Lei H, Wang X, Shi Y, Fan W, Zhao B, Wang J, Su B, Yang C, Luo Z, Chen L
Advanced healthcare materials 2024 Mar;13(6):e2303405
Advanced healthcare materials 2024 Mar;13(6):e2303405
Lentinan inhibits cell invasion via M2 polarization of tumor-associated macrophages and Wnt/β-catenin signaling in non-small cell lung cancer.
Yang Y, Cheng Y, Mu Y, Tang X, Mu X
Chemical biology & drug design 2024 Mar;103(3):e14507
Chemical biology & drug design 2024 Mar;103(3):e14507
Investigation of Expanded Human Adipose-derived Stem Cell Dosage and Timing for Improved Defecation Function.
Mori R, Miyoshi N, Fujino S, Mizushima T, Yukimoto R, Ogino T, Takahashi H, Uemura M, Doki Y, Eguchi H
In vivo (Athens, Greece) 2024 Mar-Apr;38(2):546-558
In vivo (Athens, Greece) 2024 Mar-Apr;38(2):546-558
Antibacterial, ROS scavenging and angiogenesis promotingϵ-Polylysine/gelatin based hydrogel containing CTLP to regulate macrophages for pressure ulcer healing.
Lin P, Tang X, Zhong J, Tang F, Liu H, Peng L, Wan B, Wang M, Ye Y, Guo R, Liu X, Deng L
Biofabrication 2024 Mar 7;16(2)
Biofabrication 2024 Mar 7;16(2)
Tibial cortex transverse transport promotes ischemic diabetic foot ulcer healing via enhanced angiogenesis and inflammation modulation in a novel rat model.
Qin W, Liu K, Su H, Hou J, Yang S, Pan K, Yang S, Liu J, Zhou P, Lin Z, Zhen P, Mo Y, Fan B, Li Z, Kuang X, Nie X, Hua Q
European journal of medical research 2024 Mar 6;29(1):155
European journal of medical research 2024 Mar 6;29(1):155
PGRN inhibits CD8(+)T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM.
Zhou T, Qian H, Zhang D, Fang W, Yao M, Shi H, Chen T, Chai C, Guo B
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):76
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):76
Tryptanthrin promotes pressure ulcers healing in mice by inhibiting macrophage-mediated inflammation via cGAS/STING pathways.
He Y, Yue J, Teng Y, Fan Z, Jia M, Teng H, Zhuge L
International immunopharmacology 2024 Mar 30;130:111687
International immunopharmacology 2024 Mar 30;130:111687
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Lu Y, Liu S, Wang P, Guo X, Qin Z, Hou H, Tao T
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Huang W, Wang L, Huang Z, Sun Z, Zheng B
Respiratory research 2024 Mar 2;25(1):110
Respiratory research 2024 Mar 2;25(1):110
Anti-inflammatory and anti-oxidative electrospun nanofiber membrane promotes diabetic wound healing via macrophage modulation.
He J, Zhou S, Wang J, Sun B, Ni D, Wu J, Peng X
Journal of nanobiotechnology 2024 Mar 16;22(1):116
Journal of nanobiotechnology 2024 Mar 16;22(1):116
Lipolysis inhibition improves the survival of fat grafts through ameliorating lipotoxicity and inflammation.
Niu X, Zhang Y, Lai Z, Huang X, Guo L, Lu F, Yuan Y, Gao J, Chang Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23520
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23520
Wuling capsule modulates macrophage polarization by inhibiting the TLR4-NF-κB signaling pathway to relieve liver fibrosis.
Ren S, Zhou R, Tang Z, Song Z, Li N, Shi X, Liu Y, Chu Y
International immunopharmacology 2024 Mar 10;129:111598
International immunopharmacology 2024 Mar 10;129:111598
Jiawei Taohe Chengqi decoction inhibition of the notch signal pathway affects macrophage reprogramming to inhibit HSCs activation for the treatment of hepatic fibrosis.
Shao C, Xu H, Sun X, Pan Y, Liang X, Huang J, He Y, Guo W, Ye L, Zhang J
Journal of ethnopharmacology 2024 Mar 1;321:117486
Journal of ethnopharmacology 2024 Mar 1;321:117486
Establishment of an in situ model to explore the tumor immune microenvironment in head and neck squamous cell carcinoma.
Lu C, Yang Y, Zhang M, Li J, Song H, Zhao H, Mou Y, Li Y, Song X
Head & neck 2024 Jun;46(6):1310-1321
Head & neck 2024 Jun;46(6):1310-1321
Collagen sponge scaffolds loaded with Trichostatin A pretreated BMSCs-derived exosomes regulate macrophage polarization to promote skin wound healing.
Wang T, Xue Y, Zhang W, Zheng Z, Peng X, Zhou Y
International journal of biological macromolecules 2024 Jun;269(Pt 2):131948
International journal of biological macromolecules 2024 Jun;269(Pt 2):131948
Dual-crosslinking gelatin-hyaluronic acid methacrylate based biomimetic PDAC desmoplastic niche enhances tumor-associated macrophages recruitment and M2-like polarization.
Wu D, Gong T, Sun Z, Yao X, Wang D, Chen Q, Guo Q, Li X, Guo Y, Lu Y
International journal of biological macromolecules 2024 Jun;269(Pt 1):131826
International journal of biological macromolecules 2024 Jun;269(Pt 1):131826
GO-PEG Represses the Progression of Liver Inflammation via Regulating the M1/M2 Polarization of Kupffer Cells.
Ding X, Pang Y, Liu Q, Zhang H, Wu J, Lei J, Zhang T
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(26):e2306483
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(26):e2306483
Relieving Macrophage Dysfunction by Inhibiting SREBP2 Activity: A Hypoxic Mesenchymal Stem Cells-Derived Exosomes Loaded Multifunctional Hydrogel for Accelerated Diabetic Wound Healing.
Shi Y, Wang S, Wang K, Yang R, Liu D, Liao H, Qi Y, Qiu K, Hu Y, Wen H, Xu K
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(25):e2309276
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(25):e2309276
Decreased Proteasomal Function Exacerbates Endoplasmic Reticulum Stress-Induced Chronic Inflammation in Obese Adipose Tissue.
Nakagawa S, Fukui-Miyazaki A, Yoshida T, Ishii Y, Murata E, Taniguchi K, Ishizu A, Kasahara M, Tomaru U
The American journal of pathology 2024 Jun;194(6):1033-1046
The American journal of pathology 2024 Jun;194(6):1033-1046
Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway.
Chen Y, Tao T, Liang Z, Chen X, Xu Y, Zhang T, Zhou D
Molecular immunology 2024 Jun;170:144-155
Molecular immunology 2024 Jun;170:144-155
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
Yin D, Shen G
Immunity, inflammation and disease 2024 Jun;12(6):e1274
Immunity, inflammation and disease 2024 Jun;12(6):e1274
A Graphene Composite Film Based Wearable Far-Infrared Therapy Apparatus (GRAFT) for Effective Prevention of Postoperative Peritoneal Adhesion.
Lu X, Xu L, Song Y, Yu X, Li Q, Liu F, Li X, Xi J, Wang S, Wang L, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(22):e2309330
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(22):e2309330
NIR triggered polydopamine coated cerium dioxide nanozyme for ameliorating acute lung injury via enhanced ROS scavenging.
Yin M, Lei D, Liu Y, Qin T, Gao H, Lv W, Liu Q, Qin L, Jin W, Chen Y, Liang H, Wang B, Gao M, Zhang J, Lu J
Journal of nanobiotechnology 2024 Jun 8;22(1):321
Journal of nanobiotechnology 2024 Jun 8;22(1):321
Nicotine promotes Staphylococcus aureus-induced osteomyelitis by activating the Nrf2/Slc7a11 signaling axis.
Zhou X, Ma S, Xu Y, Sun C, Liao J, Song M, Li G, Yuchen L, Chen P, Hu Y, Wang Y, Yu B
International immunopharmacology 2024 Jun 30;135:112223
International immunopharmacology 2024 Jun 30;135:112223
The STAT3 inhibitor B9 alleviates lipopolysaccharide-induced acute lung injury through its anti-inflammatory effects.
Cao L, Song H, Zhou S, Lan K, Lv K, Huang M
International immunopharmacology 2024 Jun 30;135:112221
International immunopharmacology 2024 Jun 30;135:112221
Oral microsphere formulation of M2 macrophage-mimetic Janus nanomotor for targeted therapy of ulcerative colitis.
Luo R, Liu J, Cheng Q, Shionoya M, Gao C, Wang R
Science advances 2024 Jun 28;10(26):eado6798
Science advances 2024 Jun 28;10(26):eado6798
Hyperbaric Oxygen Therapy as a Novel Approach to Modulating Macrophage Polarization for the Treatment of Glioblastoma.
Yuen CM, Tsai HP, Tseng TT, Tseng YL, Lieu AS, Kwan AL, Chang AYW
Biomedicines 2024 Jun 21;12(7)
Biomedicines 2024 Jun 21;12(7)
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Zhao Q, Zhang Z, Zhou X, Rong X, Liu X, Zhao X, Wang H, Pang J, Li S, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Sr-Incorporated Bioactive Glass Remodels the Immunological Microenvironment by Enhancing the Mitochondrial Function of Macrophage via the PI3K/AKT/mTOR Signaling Pathway.
Qiu H, Xiong H, Zheng J, Peng Y, Wang C, Hu Q, Zhao F, Chen K
ACS biomaterials science & engineering 2024 Jun 10;10(6):3923-3934
ACS biomaterials science & engineering 2024 Jun 10;10(6):3923-3934
tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer.
Mo D, Tang X, Ma Y, Chen D, Xu W, Jiang N, Zheng J, Yan F
Journal of translational medicine 2024 Jul 30;22(1):706
Journal of translational medicine 2024 Jul 30;22(1):706
Perinatal loss of galactosylceramidase in both oligodendrocytes and microglia is crucial for the pathogenesis of Krabbe disease in mice.
Favret J, Nawaz MH, Patel M, Khaledi H, Gelb M, Shin D
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jul 3;32(7):2207-2222
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jul 3;32(7):2207-2222
Multifunctional Microneedle Patch Based on Metal-Phenolic Network with Photothermal Antimicrobial, ROS Scavenging, Immunomodulatory, and Angiogenesis for Programmed Treatment of Diabetic Wound Healing.
Guo Y, Zhang C, Xie B, Xu W, Rao Z, Zhou P, Ma X, Chen J, Cai R, Tao G, He Y
ACS applied materials & interfaces 2024 Jul 3;16(26):33205-33222
ACS applied materials & interfaces 2024 Jul 3;16(26):33205-33222
HMGB1/TREM2 positive feedback loop drives the development of radioresistance and immune escape of glioblastoma by regulating TLR4/Akt signaling.
Qiu H, Shao Z, Wen X, Qu D, Liu Z, Chen Z, Zhang X, Ding X, Zhang L
Journal of translational medicine 2024 Jul 29;22(1):688
Journal of translational medicine 2024 Jul 29;22(1):688
Icariside II modulates pulmonary fibrosis via PI3K/Akt/β-catenin pathway inhibition of M2 macrophage program.
Deng L, Ouyang B, Tang W, Wang N, Yang F, Shi H, Zhang Z, Yu H, Chen M, Wei Y, Dong J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155687
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155687
Engineered Mesenchymal Stromal Cell Exosomes-Loaded Microneedles Improve Corneal Healing after Chemical Injury.
Yu F, Zhao X, Wang Q, Fang PH, Liu L, Du X, Li W, He D, Zhang T, Bai Y, Liu L, Li S, Yuan J
ACS nano 2024 Jul 24;
ACS nano 2024 Jul 24;
Shape-fixing hydrogel promotes scarless healing of wounds under tension.
Fu D, Huang J, Wu X, Li Y, Zhang Y, Chen L, Liu Z, He Y, Zhou Y, Yang L, Hu Z, Miao Y
Acta biomaterialia 2024 Jul 15;183:173-190
Acta biomaterialia 2024 Jul 15;183:173-190
MSCs-exosomes can promote macrophage M2 polarization via exosomal miR-21-5p through Mesenteric injection: a promising way to attenuate murine colitis.
Qian W, Wu E, Chen H, Yao J, Wang J, Zhou Y, Bai Y, Wang S, Shen C, Li Y, Zhang Y
Journal of Crohn's & colitis 2024 Jul 13;
Journal of Crohn's & colitis 2024 Jul 13;
LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.
Lin H, Fu L, Zhou X, Yu A, Chen Y, Liao W, Shu G, Zhang L, Tan L, Liang H, Wang Z, Deng Q, Wang J, Jin M, Chen Z, Wei J, Cao J, Chen W, Li X, Li P, Lu J, Luo J
Cancer letters 2024 Jul 1;593:216807
Cancer letters 2024 Jul 1;593:216807
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis.
Liu Y, Zhao Y, Liu Q, Li B, Daniel PV, Chen B, Wu Z
Journal of lipid research 2024 Jan;65(1):100483
Journal of lipid research 2024 Jan;65(1):100483
Gab2 promotes the growth of colorectal cancer by regulating the M2 polarization of tumor‑associated macrophages.
Gao X, Long R, Qin M, Zhu W, Wei L, Dong P, Chen J, Luo J, Feng J
International journal of molecular medicine 2024 Jan;53(1)
International journal of molecular medicine 2024 Jan;53(1)
Ultrasound-triggered biomimetic ultrashort peptide nanofiber hydrogels promote bone regeneration by modulating macrophage and the osteogenic immune microenvironment.
Zhang F, Lv M, Wang S, Li M, Wang Y, Hu C, Hu W, Wang X, Wang X, Liu Z, Fan Z, Du J, Sun Y
Bioactive materials 2024 Jan;31:231-246
Bioactive materials 2024 Jan;31:231-246
Sprayable chitosan nanogel with nitric oxide to accelerate diabetic wound healing through bacteria inhibition, biofilm eradication and macrophage polarization.
Huang Q, Yang Z, Tao X, Ma C, Cao P, Wei P, Jiang C, Ren H, Li X
International journal of biological macromolecules 2024 Jan;254(Pt 1):127806
International journal of biological macromolecules 2024 Jan;254(Pt 1):127806
Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.
Zhang J, Tu Y, Wei J, Zheng R, Shao J, Chen Q, Liang G, Ying H, Han X, Shi Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166911
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166911
Hinokitiol as a modulator of TLR4 signaling and apoptotic pathways in atopic dermatitis.
Tai LR, Chiang YF, Huang KC, Chen HY, Ali M, Hsia SM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116026
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116026
NIR-Actuated Targeted Janus Nanomotors Remodel Immunosuppressive Tumor Microenvironment for Augmented Cancer Immunotherapy.
Zhou X, Ma E, Zhang Y, Xing Y, Xu W, Chen L, Zhou H, Zhang X, Jiang C, Xu K, Wang H, Zheng S
Advanced healthcare materials 2024 Jan;13(2):e2302272
Advanced healthcare materials 2024 Jan;13(2):e2302272
Macelignan prevents colorectal cancer metastasis by inhibiting M2 macrophage polarization.
Che N, Li M, Liu X, Cui CA, Gong J, Xuan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155144
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155144
Urethral Microenvironment Adapted Sodium Alginate/Gelatin/Reduced Graphene Oxide Biomimetic Patch Improves Scarless Urethral Regeneration.
Wang L, Wang K, Yang M, Yang X, Li D, Liu M, Niu C, Zhao W, Li W, Fu Q, Zhang K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2302574
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2302574
Carveol alleviates osteoarthritis progression by acting on synovial macrophage polarization transformation: An in vitro and in vivo study.
Chen S, Xu H, He Y, Meng C, Fan Y, Qu Y, Wang Y, Zhou W, Huang X, You H
Chemico-biological interactions 2024 Jan 5;387:110781
Chemico-biological interactions 2024 Jan 5;387:110781
Discovery of β-sitosterol's effects on molecular changes in rat diabetic wounds and its impact on angiogenesis and macrophages.
Liu Y, Li Z, Li W, Chen X, Yang L, Lu S, Zhou S, Li M, Xiong W, Zhang X, Liu Y, Zhou J
International immunopharmacology 2024 Jan 5;126:111283
International immunopharmacology 2024 Jan 5;126:111283
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.
Shuangshuang H, Mengmeng S, Lan Z, Fang Z, Yu L
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308
Targeted mRNA Nanoparticles Ameliorate Blood-Brain Barrier Disruption Postischemic Stroke by Modulating Microglia Polarization.
Gao M, Li Y, Ho W, Chen C, Chen Q, Li F, Tang M, Fan Q, Wan J, Yu W, Xu X, Li P, Zhang XQ
ACS nano 2024 Jan 30;18(4):3260-3275
ACS nano 2024 Jan 30;18(4):3260-3275
Rutin prevents pyroptosis and M1 microglia via Nrf2/Mac-1/caspase-1-mediated inflammasome axis to improve POCD.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Jin D, Xu L, Ge S
International immunopharmacology 2024 Jan 25;127:111290
International immunopharmacology 2024 Jan 25;127:111290
Synergistic Amelioration of Osseointegration and Osteoimmunomodulation with a Microarc Oxidation-Treated Three-Dimensionally Printed Ti-24Nb-4Zr-8Sn Scaffold via Surface Activity and Low Elastic Modulus.
Yang X, Wu L, Li C, Li S, Hou W, Hao Y, Lu Y, Li L
ACS applied materials & interfaces 2024 Jan 24;16(3):3171-3186
ACS applied materials & interfaces 2024 Jan 24;16(3):3171-3186
High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cells.
Hui Y, Kuang L, Zhong Y, Tang Y, Xu Z, Zheng T
iScience 2024 Jan 19;27(1):108689
iScience 2024 Jan 19;27(1):108689
Metformin protects ovarian granulosa cells in chemotherapy-induced premature ovarian failure mice through AMPK/PPAR-γ/SIRT1 pathway.
Yang Y, Tang X, Yao T, Zhang Y, Zhong Y, Wu S, Wang Y, Pan Z
Scientific reports 2024 Jan 16;14(1):1447
Scientific reports 2024 Jan 16;14(1):1447
Salvianolic Acid B Alleviates Liver Injury by Regulating Lactate-Mediated Histone Lactylation in Macrophages.
Hu S, Yang Z, Li L, Yan Q, Hu Y, Zhou F, Tan Y, Pei G
Molecules (Basel, Switzerland) 2024 Jan 1;29(1)
Molecules (Basel, Switzerland) 2024 Jan 1;29(1)
TREM2 regulates BV2 microglia activation and influences corticosterone-induced neuroinflammation in depressive disorders.
Shi J, Wang X, Kang C, Liu J, Ma C, Yang L, Hu J, Zhao N
Brain research 2024 Jan 1;1822:148664
Brain research 2024 Jan 1;1822:148664
Reprogramming tumor-associated macrophages by a dually targeted milk exosome system as a potent monotherapy for cancer.
Chen Y, Gong L, Cao Y, Liu Z, Wang Y, Cheng H, Feng Y, Yao S, Yin Y, Wu Z, Huang Z
Journal of controlled release : official journal of the Controlled Release Society 2024 Feb;366:395-409
Journal of controlled release : official journal of the Controlled Release Society 2024 Feb;366:395-409
Efficient pulmonary fibrosis therapy via regulating macrophage polarization using respirable cryptotanshinone-loaded liposomal microparticles.
Wang X, Wan W, Zhang J, Lu J, Liu P
Journal of controlled release : official journal of the Controlled Release Society 2024 Feb;366:1-17
Journal of controlled release : official journal of the Controlled Release Society 2024 Feb;366:1-17
Reprogramming macrophages via immune cell mobilized hydrogel microspheres for osteoarthritis treatments.
Xiao P, Han X, Huang Y, Yang J, Chen L, Cai Z, Hu N, Cui W, Huang W
Bioactive materials 2024 Feb;32:242-259
Bioactive materials 2024 Feb;32:242-259
Human umbilical cord derived mesenchymal stem cells overexpressing HO-1 attenuate neural injury and enhance functional recovery by inhibiting inflammation in stroke mice.
Yang Y, Liu Q, Deng S, Shao Q, Peng L, Ling Y, Huang Y, Zheng S, Jiang Q, Nie D, Chen J
CNS neuroscience & therapeutics 2024 Feb;30(2):e14412
CNS neuroscience & therapeutics 2024 Feb;30(2):e14412
Alleviating 3-MCPD-induced male reproductive toxicity: Mechanistic insights and resveratrol intervention.
Wang KL, Chiang YF, Huang KC, Chen HY, Ali M, Hsia SM
Ecotoxicology and environmental safety 2024 Feb;271:115978
Ecotoxicology and environmental safety 2024 Feb;271:115978
MMP14(high) macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis.
Peng D, Li J, Li Y, Bai L, Xiong A, He X, Li X, Ran Q, Zhang L, Jiang M, Wang J, Leung EL, Yang P, Li G
Pharmacological research 2024 Feb;200:107070
Pharmacological research 2024 Feb;200:107070
Photobiomodulation therapy alleviates repeated closed head injury-induced anxiety-like behaviors.
Chen Z, Li M, Wu C, Su Y, Feng S, Deng Q, Zou P, Liu TC, Duan R, Yang L
Journal of biophotonics 2024 Feb;17(2):e202300343
Journal of biophotonics 2024 Feb;17(2):e202300343
Troxerutin dampened hypothalamic neuroinflammation via microglial IL-22/IL-22R1/IRF3 activation in dihydrotestosterone-induced polycystic ovary syndrome rats.
Gao Z, Tan H, Song X, Zhuang T, Kong R, Wang Y, Yan X, Yao R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155280
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155280
Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
Luan X, Lei T, Fang J, Liu X, Fu H, Li Y, Chu W, Jiang P, Tong C, Qi H, Fu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Fabrication of levofloxacin-loaded porcine acellular dermal matrix hydrogel and functional assessment in urinary tract infection.
Yang Y, Yang GW, Lu JJ, Chen HR, Guo YQ, Yang N, Zhu YZ, Liu XQ, Su TT, Liu YY, Yu L, Li YS, Hu LF, Li JB
Journal of nanobiotechnology 2024 Feb 7;22(1):52
Journal of nanobiotechnology 2024 Feb 7;22(1):52
Protective effect of Tetrandrine on optic nerve by inhibiting glial activation through NF-κB pathway.
Li W, Cao J, Liu J, Chen S, Dai M, Zhang M, Hou X, Wang J, Kang Z
Heliyon 2024 Feb 29;10(4):e24749
Heliyon 2024 Feb 29;10(4):e24749
Periodontitis aggravates COPD through the activation of γδ T cell and M2 macrophage.
Xiong K, Ao K, Wei W, Dong J, Li J, Yang Y, Tang B, Li Y
mSystems 2024 Feb 20;9(2):e0057223
mSystems 2024 Feb 20;9(2):e0057223
TRIM65 knockout inhibits the development of HCC by polarization tumor-associated macrophages towards M1 phenotype via JAK1/STAT1 signaling pathway.
Jiang M, Wang D, Su N, Lou W, Chen Y, Yang H, Chen C, Xi F, Chen Y, Deng L, Tang X
International immunopharmacology 2024 Feb 15;128:111494
International immunopharmacology 2024 Feb 15;128:111494
Moluodan promotes DSS-induced intestinal inflammation involving the reprogram of macrophage function and polarization.
Zhao M, Qiao C, Cui Z, Zhang W, Yang S, Zhu C, Du F, Ning T, Xie S, Liu S, Li P, Xu J, Zhu S
Journal of ethnopharmacology 2024 Feb 10;320:117393
Journal of ethnopharmacology 2024 Feb 10;320:117393
Bromodomain containing 4 inhibition combats gastric precancerous lesions via modulating macrophage polarization.
Zhu L, Cai Q, Li G, Zou X
Tissue & cell 2024 Dec;91:102580
Tissue & cell 2024 Dec;91:102580
An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Xu L, Ge S
Molecular neurobiology 2024 Dec;61(12):10097-10114
Molecular neurobiology 2024 Dec;61(12):10097-10114
Histone Lactylation-Driven GPD2 Mediates M2 Macrophage Polarization to Promote Malignant Transformation of Cervical Cancer Progression.
Huang C, Xue L, Lin X, Shen Y, Wang X
DNA and cell biology 2024 Dec;43(12):605-618
DNA and cell biology 2024 Dec;43(12):605-618
Microenvironment-responsive nano-bioconjugated vesicles for the multi-pronged treatment of liver fibrosis.
Xing JH, Hou LS, Zhang K, Zhang YW, Zheng C, Cai Z, Sui B, Zhou SY, He W, Zhang BL
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:52-66
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:52-66
Bioactive sucralfate-based microneedles promote wound healing through reprogramming macrophages and protecting endogenous growth factors.
Le Z, Ramos MC, Shou Y, Li RR, Cheng HS, Jang CJ, Liu L, Xue C, Li X, Liu H, Lim CT, Tan NS, White AD, Charles CJ, Chen Y, Liu Z, Tay A
Biomaterials 2024 Dec;311:122700
Biomaterials 2024 Dec;311:122700
A Novel Compound Ligusticum Cycloprolactam Alleviates Neuroinflammation After Ischemic Stroke via the FPR1/NLRP3 Signaling Axis.
Gao J, Su G, Liu J, Song J, Chen W, Chai M, Xie X, Wang M, Liu J, Zhang Z
CNS neuroscience & therapeutics 2024 Dec;30(12):e70158
CNS neuroscience & therapeutics 2024 Dec;30(12):e70158
Single-cell RNA sequencing reveals the intercellular crosstalk and the regulatory landscape of stromal cells during the whole life of the mouse ovary.
Jiang W, Sun W, Peng Y, Xu H, Fan H, Jin X, Xiao Y, Wang Y, Yang P, Shu W, Li J
Life medicine 2024 Dec;3(6):lnae041
Life medicine 2024 Dec;3(6):lnae041
MSCs-derived ECM functionalized hydrogel regulates macrophage reprogramming for osteoarthritis treatment by improving mitochondrial function and energy metabolism.
Chen Z, Pang Q, Zhan J, Liu J, Zhao W, Dong L, Huang W
Materials today. Bio 2024 Dec;29:101340
Materials today. Bio 2024 Dec;29:101340
Licochalcone A loaded multifunctional chitosan hyaluronic acid hydrogel with antibacterial and inflammatory regulating effects to promote wound healing.
Hou Z, Wang Y, Chen S, Luo Z, Liu Y
International journal of biological macromolecules 2024 Dec;283(Pt 1):137458
International journal of biological macromolecules 2024 Dec;283(Pt 1):137458
Multifunctional carboxymethyl chitosan/oxidized carboxymethyl cellulose hydrogel loaded with ginsenoside Rg1 and polydopamine nanoparticles for infected diabetic wound healing.
Li S, Ren X, Liu Y, Wang L, Zhou Y, Zhang Y, Yan Z, Lan X, Guo L
International journal of biological macromolecules 2024 Dec;282(Pt 1):136686
International journal of biological macromolecules 2024 Dec;282(Pt 1):136686
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway.
Luo W, Meng J, Yu XH, Zhang ZZ, Wang G, He J
Journal of cellular and molecular medicine 2024 Dec;28(24):e70263
Journal of cellular and molecular medicine 2024 Dec;28(24):e70263
Spatial dimension cues derived from fibrous scaffolds trigger mechanical activation to potentiate the paracrine and regenerative functions of MSCs via the FAK-PI3K/AKT axis.
Xu S, Zhang M, Wang R, Zhang J, Wang C, Xie L, Zhao W
Acta biomaterialia 2024 Dec;190:273-292
Acta biomaterialia 2024 Dec;190:273-292
Controlled Release of Ceria and Ferric Oxide Nanoparticles via Collagen Hydrogel for Enhanced Osteoarthritis Therapy.
Chen X, Wang L, Zhang J, Yan H, Wang S, Xiao J
Advanced healthcare materials 2024 Dec;13(32):e2401507
Advanced healthcare materials 2024 Dec;13(32):e2401507
Hierarchical Integration of Curcumin-Loaded CaCO(3) Nanoparticles and Black Phosphorus Nanosheets in Core/Shell Nanofiber for Cranial Defect Repair.
Zheng Y, Tan L, Chen H, He S, Li M, Luo Z, Cai K, Hu Y
Advanced healthcare materials 2024 Dec;13(30):e2401786
Advanced healthcare materials 2024 Dec;13(30):e2401786
A Core-Brush Nanoplatform with Enhanced Lubrication and Anti-Inflammatory Properties for Osteoarthritis Treatment.
Liu Y, Ma Z, Wang X, Liang J, Zhao L, Zhang Y, Ren J, Zhang S, Liu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2406027
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2406027
Adropin regulates macrophage phenotype via PPARγ signalling: A preliminary study of adropin and Crohn's disease.
Zeng L, Chen J, Xie H, Liu W, Wang C
Scandinavian journal of immunology 2024 Dec;100(6):e13415
Scandinavian journal of immunology 2024 Dec;100(6):e13415
Treadmill exercise improves cerebral ischemia injury by regulating microglia polarization via downregulation of MMP12.
Zhang S, Fan Y, Cao X, Deng C, Xu J, Zhou Q, Li Y, Yin Y, Chen H
International immunopharmacology 2024 Dec 5;142(Pt B):113210
International immunopharmacology 2024 Dec 5;142(Pt B):113210
Kaempferol improves depression-like behaviors through shifting microglia polarization and suppressing NLRP3 via tilting the balance of PPARγ and STAT1 signaling.
Su P, Liu L, Gong Y, Peng S, Yan X, Bai M, Xu E, Li Y
International immunopharmacology 2024 Dec 25;143(Pt 3):113538
International immunopharmacology 2024 Dec 25;143(Pt 3):113538
Caulerpin alleviates cyclophosphamide-induced ovarian toxicity by modulating macrophage-associated granulosa cell senescence during breast cancer chemotherapy.
Ren X, Yao B, Zhou X, Nie P, Xu S, Wang M, Li P
International immunopharmacology 2024 Dec 25;143(Pt 3):113513
International immunopharmacology 2024 Dec 25;143(Pt 3):113513
FOXF2 suppressed esophageal squamous cell carcinoma by reducing M2 TAMs via modulating RNF144A-FTO axis.
Han T, Tong W, Xie J, Guo X, Zhang L
International immunopharmacology 2024 Dec 25;143(Pt 2):113422
International immunopharmacology 2024 Dec 25;143(Pt 2):113422
HPV11 targeting KDM4A regulates the polarization of macrophage M(1) and promotes the development of nasal inverted papilloma.
Zheng L, Hu B, Yao W, Tian K, Zhu G, Jin M, Huang S, Chen X, Zhang Y
Cell communication and signaling : CCS 2024 Dec 18;22(1):603
Cell communication and signaling : CCS 2024 Dec 18;22(1):603
Autophagy-mediated activation of the AIM2 inflammasome enhances M1 polarization of microglia and exacerbates retinal neovascularization.
Liu X, Zhou Q, Meng J, Zuo H, Li R, Zhang R, Lu H, Zhang Z, Li H, Zeng S, Tian M, Wang H, Hu K, Li N, Mao L, Hou S
MedComm 2024 Aug;5(8):e668
MedComm 2024 Aug;5(8):e668
DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis.
Cui Y, Hu Z, Wang L, Zhu B, Deng L, Zhang H, Wang X
Neurochemical research 2024 Aug;49(8):2215-2227
Neurochemical research 2024 Aug;49(8):2215-2227
HSP110 aggravates ischemia-reperfusion injury after liver transplantation by promoting NF-κB pathway.
Hu QZ, Cao ZR, Zheng WX, Zhao MJ, Gong JH, Chen C, Wu ZJ, Tao R
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Aug;23(4):344-352
Hepatobiliary & pancreatic diseases international : HBPD INT 2024 Aug;23(4):344-352
Dissection of triple-negative breast cancer microenvironment and identification of potential therapeutic drugs using single-cell RNA sequencing analysis.
Cheng W, Mi W, Wang S, Wang X, Jiang H, Chen J, Yang K, Jiang W, Ye J, Guo B, Zhang Y
Journal of pharmaceutical analysis 2024 Aug;14(8):100975
Journal of pharmaceutical analysis 2024 Aug;14(8):100975
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Li L, Zhai M, Cheng C, Cui S, Wang J, Zhang Z, Liu J, Wei F
Progress in orthodontics 2024 Aug 5;25(1):30
Progress in orthodontics 2024 Aug 5;25(1):30
rTMS applied to the PFC relieves neuropathic pain and modulates neuroinflammation in CCI rats.
Yang Y, Xia C, Xu Z, Hu Y, Huang M, Li D, Zheng Y, Li Y, Xu F, Wang J
Neuroscience 2024 Aug 30;554:137-145
Neuroscience 2024 Aug 30;554:137-145
Apilarnil exerts neuroprotective effects and alleviates motor dysfunction by rebalancing M1/M2 microglia polarization, regulating miR-155 and miR-124 expression in a rotenone-induced Parkinson's disease rat model.
Salama RM, Darwish SF, Yehia R, Eissa N, Elmongy NF, Abd-Elgalil MM, Schaalan MF, El Wakeel SA
International immunopharmacology 2024 Aug 20;137:112536
International immunopharmacology 2024 Aug 20;137:112536
Adipose-derived stem cell exosomes loaded with icariin attenuated M1 polarization of macrophages via inhibiting the TLR4/Myd88/NF-κB signaling pathway.
Yan Q, Song C, Liu H, Li Y, Ma J, Zhao Y, Song Z, Chen Y, Zhu R, Zhang Z
International immunopharmacology 2024 Aug 20;137:112448
International immunopharmacology 2024 Aug 20;137:112448
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
Gao Y, Mao J, Zhang R, Deng Q, Wang Y, Pan Y, Liudi S, Wang Y, Fan X, Yang Y, Wan S
European journal of pharmacology 2024 Aug 15;977:176673
European journal of pharmacology 2024 Aug 15;977:176673
Peimine promotes microglial polarization to the M2 phenotype to attenuate drug-resistant epilepsy through suppressing the TLR4/NF-κB/HIF-1α signaling pathway in a rat model and in BV-2 microglia.
Liu C, Sun J, Shen X, Li S, Luo S, Chen N, Zhang Y
Heliyon 2024 Aug 15;10(15):e34987
Heliyon 2024 Aug 15;10(15):e34987
Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway.
Ji R, Hao Z, Wang H, Su Y, Yang W, Li X, Duan L, Guan F, Ma S
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17964-17976
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17964-17976
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages.
Ji Q, Li Z, Guo Y, Zhang X
Aging 2024 Aug 13;16(15):11513-11534
Aging 2024 Aug 13;16(15):11513-11534
Upregulation of MELK promotes chemoresistance and induces macrophage M2 polarization via CSF-1/JAK2/STAT3 pathway in gastric cancer.
Su P, Yu T, Zhang Y, Huang H, Chen M, Cao C, Kang W, Liu Y, Yu J
Cancer cell international 2024 Aug 12;24(1):287
Cancer cell international 2024 Aug 12;24(1):287
Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury.
Kou Y, Yuan Y, Li Q, Xie W, Xu H, Han N
Neural regeneration research 2024 Aug 1;19(8):1822-1827
Neural regeneration research 2024 Aug 1;19(8):1822-1827
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Jin D, Xu L, Ge S
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway.
Wang Z, Zhang X, Lv M, Cao S, Yang G, Zhang Z, Yu Q
Immunologic research 2024 Apr;72(2):271-283
Immunologic research 2024 Apr;72(2):271-283
Multifunctional nanocoatings with synergistic controlled release of zinc ions and cytokines for precise modulation of vascular intimal reconstruction.
Tan J, Wang H, Liu S, Li L, Liu H, Liu T, Chen J
Nanomedicine : nanotechnology, biology, and medicine 2024 Apr;57:102739
Nanomedicine : nanotechnology, biology, and medicine 2024 Apr;57:102739
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Zeng J, Lu QQ, Du XL, Yuan L, Yang XJ
Journal of molecular histology 2024 Apr;55(2):201-210
Journal of molecular histology 2024 Apr;55(2):201-210
IRF4 induces M1 macrophage polarization and aggravates ulcerative colitis progression by the Bcl6-dependent STAT3 pathway.
Wang J, Wu Z, Huang Y, Jin L, Xu J, Yao Z, Ouyang X, Zhou Z, Mao S, Cao J, Lai B, Shen W
Environmental toxicology 2024 Apr;39(4):2390-2404
Environmental toxicology 2024 Apr;39(4):2390-2404
Effect of Low-Intensity Pulsed Ultrasound on Macrophage Properties and Fibrosis in the Infrapatellar Fat Pad in a Carrageenan-Induced Knee Osteoarthritis Rat Model.
Kitagawa T, Kawahata H, Kudo S
Cureus 2024 Apr;16(4):e59246
Cureus 2024 Apr;16(4):e59246
Ferrous/Ferric Ions Crosslinked Type II Collagen Multifunctional Hydrogel for Advanced Osteoarthritis Treatment.
Wang L, Chen X, Wang S, Ma J, Yang X, Chen H, Xiao J
Advanced healthcare materials 2024 Apr;13(10):e2302833
Advanced healthcare materials 2024 Apr;13(10):e2302833
Dehydroandrographolide facilitates M2 macrophage polarization by downregulating DUSP3 to inhibit sepsis-associated acute kidney injury.
Shao Y, Yu W, Cai H
Immunity, inflammation and disease 2024 Apr;12(4):e1249
Immunity, inflammation and disease 2024 Apr;12(4):e1249
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
Liu B, Xian Y, Chen X, Shi Y, Dong J, Yang L, An X, Shen T, Wu W, Ma Y, He Y, Gong W, Peng R, Lin J, Liu N, Guo B, Jiang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment.
Liu L, Ma Z, Han Q, Meng W, Wang H, Guan X, Shi Q
ACS nano 2024 Apr 9;18(14):9895-9916
ACS nano 2024 Apr 9;18(14):9895-9916
Buyang Huanwu Decoction promotes neurovascular remodeling by modulating astrocyte and microglia polarization in ischemic stroke rats.
Li MC, Li MZ, Lin ZY, Zhuang YM, Wang HY, Jia JT, Lu Y, Wang ZJ, Zou HY, Zhao H
Journal of ethnopharmacology 2024 Apr 6;323:117620
Journal of ethnopharmacology 2024 Apr 6;323:117620
Bioactive fiber-reinforced hydrogel to tailor cell microenvironment for structural and functional regeneration of myotendinous junction.
Sun Y, Sheng R, Cao Z, Liu C, Li J, Zhang P, Du Y, Mo Q, Yao Q, Chen J, Zhang W
Science advances 2024 Apr 26;10(17):eadm7164
Science advances 2024 Apr 26;10(17):eadm7164
Interleukin-1β polarization in M1 macrophage mediates myocardial fibrosis in diabetes.
Guo W, Yang C, Zou J, Yu T, Li M, He R, Chen K, Hell RCR, Gross ER, Zou X, Lu Y
International immunopharmacology 2024 Apr 20;131:111858
International immunopharmacology 2024 Apr 20;131:111858
Intratumor microbiome-derived butyrate promotes lung cancer metastasis.
Ma Y, Chen H, Li H, Zheng M, Zuo X, Wang W, Wang S, Lu Y, Wang J, Li Y, Wang J, Qiu M
Cell reports. Medicine 2024 Apr 16;5(4):101488
Cell reports. Medicine 2024 Apr 16;5(4):101488
FDA compound library screening Baicalin upregulates TREM2 for the treatment of cerebral ischemia-reperfusion injury.
Wang H, Ma J, Li X, Peng Y, Wang M
European journal of pharmacology 2024 Apr 15;969:176427
European journal of pharmacology 2024 Apr 15;969:176427
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Wang Y, Pan Z, Cui J, Zhang X, Li D, Sun H, Yang B, Li Y
Acta biomaterialia 2024 Apr 1;178:68-82
Acta biomaterialia 2024 Apr 1;178:68-82
LncRNA HCG18 loaded by polymorphonuclear neutrophil-secreted exosomes aggravates sepsis acute lung injury by regulating macrophage polarization.
Zhu L, Yu Y, Wang H, Wang M, Chen M
Clinical hemorheology and microcirculation 2023;85(1):13-30
Clinical hemorheology and microcirculation 2023;85(1):13-30
Pathological BBB Crossing Melanin-Like Nanoparticles as Metal-Ion Chelators and Neuroinflammation Regulators against Alzheimer's Disease.
Huang Q, Jiang C, Xia X, Wang Y, Yan C, Wang X, Lei T, Yang X, Yang W, Cheng G, Gao H
Research (Washington, D.C.) 2023;6:0180
Research (Washington, D.C.) 2023;6:0180
A Novel Poly(3-hexylthiophene) Engineered Interface for Electrochemical Monitoring of Ascorbic Acid During the Occurrence of Glutamate-Induced Brain Cytotoxic Edemas.
Meng Z, Zhang Y, Yang L, Zhao S, Zhou Q, Chen J, Sui J, Wang J, Guo L, Chang L, He J, Wang G, Zang G
Research (Washington, D.C.) 2023;6:0149
Research (Washington, D.C.) 2023;6:0149
Pachymic Acid Prevents Hemorrhagic Shock-Induced Cardiac Injury by Suppressing M1 Macrophage Polarization and NF-[Formula: see text]B Signaling Pathway.
Liu Z, Zhou W, Liu Q, Huan Z, Wang Q, Ge X
The American journal of Chinese medicine 2023;51(8):2157-2173
The American journal of Chinese medicine 2023;51(8):2157-2173
Heme-heme oxygenase-2 reduces the atherosclerosis by preventing inflammation.
Wang Z, Zhan X, Yang S, Chen Y, Bi Y, Xian X, Chen Q, Han X, Yang Z, Chen R
Current research in pharmacology and drug discovery 2023;4:100141
Current research in pharmacology and drug discovery 2023;4:100141
P-Glycoprotein Exacerbates Brain Injury Following Experimental Cerebral Ischemia by Promoting Proinflammatory Microglia Activation.
Chen Y, Fei X, Liu G, Li X, Huang L, Yang LZ, Li Y, Xu B, Fang W
Oxidative medicine and cellular longevity 2023;2023:6916819
Oxidative medicine and cellular longevity 2023;2023:6916819
Comprehensive Analysis Identified Glycosyltransferase Signature to Predict Glioma Prognosis and TAM Phenotype.
Qi Y, Lv W, Liu X, Wang Q, Xing B, Jiang Q, Wang Z, Huang Y, Shu K, Lei T
BioMed research international 2023;2023:6082635
BioMed research international 2023;2023:6082635
Radioimmunotherapy Targeting B7-H3 in situ glioma models enhanced antitumor efficacy by Reconstructing the tumor microenvironment.
Zheng M, Wang Y, Fu F, Zhang K, Wang Y, Zhao S, Liu Q, Mu H, Zhang X, Miao L
International journal of biological sciences 2023;19(13):4278-4290
International journal of biological sciences 2023;19(13):4278-4290
Neural Stem Cell-Derived Exosomes Improve Neurological Function in Rats with Cerebral Ischemia-Reperfusion Injury by Regulating Microglia-Mediated Inflammatory Response.
Zhao X, Zhu J, Chen S, Liu R, Long T
Journal of inflammation research 2023;16:3079-3092
Journal of inflammation research 2023;16:3079-3092
Major vault protein regulates tumor-associated macrophage polarization through interaction with signal transducer and activator of transcription 6.
Yu C, Zhu Q, Ma C, Luo C, Nie L, Cai H, Wang Q, Wang F, Ren H, Yan H, Xu K, Zhou L, Zhang C, Lu G, Lu Z, Zhu Y, Liu S
Frontiers in immunology 2023;14:1289795
Frontiers in immunology 2023;14:1289795
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
Shu H, Wang Y, Zhang H, Dong Q, Sun L, Tu Y, Liao Q, Feng L, Yao L
Frontiers in pharmacology 2023;14:1169054
Frontiers in pharmacology 2023;14:1169054
The immunomodulatory effect of IL-4 accelerates bone substitute material-mediated osteogenesis in aged rats via NLRP3 inflammasome inhibition.
Li D, Li X, Zhang J, Tang Z, Tian A
Frontiers in immunology 2023;14:1121549
Frontiers in immunology 2023;14:1121549
High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization.
Feng S, Wu C, Zou P, Deng Q, Chen Z, Li M, Zhu L, Li F, Liu TC, Duan R, Yang L
Theranostics 2023;13(10):3434-3450
Theranostics 2023;13(10):3434-3450
Sialidase facilitates Porphyromonas gingivalis immune evasion by reducing M1 polarization, antigen presentation, and phagocytosis of infected macrophages.
Fan X, Zheng S, Chen C, Lin L, Wang H, Shen Y, Pan Y, Li C
Frontiers in cellular and infection microbiology 2023;13:1173899
Frontiers in cellular and infection microbiology 2023;13:1173899
Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.
Yi C, Wu S, Duan Q, Liu L, Li L, Luo Y, Wang A
PeerJ 2023;11:e15060
PeerJ 2023;11:e15060
Thermos-responsive hydrogel system encapsulated engineered exosomes attenuate inflammation and oxidative damage in acute spinal cord injury.
Xiao Y, Hu X, Jiang P, Qi Z
Frontiers in bioengineering and biotechnology 2023;11:1216878
Frontiers in bioengineering and biotechnology 2023;11:1216878
Comparison of proteomic landscape of extracellular vesicles in pleural effusions isolated by three strategies.
Yao X, Liao B, Chen F, Liu L, Wu K, Hao Y, Li Y, Wang Y, Fan R, Yin J, Liu L, Guo Y
Frontiers in bioengineering and biotechnology 2023;11:1108952
Frontiers in bioengineering and biotechnology 2023;11:1108952
BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.
Wei X, Huang C, Chen K, Liu S, Wang M, Yang L, Wang Y
Neurochemical research 2023 Sep;48(9):2687-2700
Neurochemical research 2023 Sep;48(9):2687-2700
Early depletion of M1 macrophages retards the progression of glucocorticoid-associated osteonecrosis of the femoral head.
Cheng Y, Chen H, Duan P, Zhang H, Yu Y, Yu J, Yu Z, Zheng L, Ye X, Pan Z
International immunopharmacology 2023 Sep;122:110639
International immunopharmacology 2023 Sep;122:110639
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51
Neuroscience 2023 Sep 1;527:37-51
Intrinsic contractile dysfunction due to impaired sarcoplasmic reticulum Ca(2+) release in compensatory hypertrophied muscle fibers following synergist ablation.
Tokuda N, Watanabe D, Naito A, Yamauchi N, Ashida Y, Cheng AJ, Yamada T
American journal of physiology. Cell physiology 2023 Sep 1;325(3):C599-C612
American journal of physiology. Cell physiology 2023 Sep 1;325(3):C599-C612
Yangqing Chenfei formula alleviates crystalline silica induced pulmonary inflammation and fibrosis by suppressing macrophage polarization.
Xinrong T, Runsu H, Xinguang L, Peng Z, Yange T, Jiansheng LI
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(6):1126-1139
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(6):1126-1139
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression.
Ma Z, Mo R, Yang P, Ding Y, Zhang H, Dong Z, Chen Y, Tan Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23215
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23215
The infrapatellar fat pad contributes to spontaneous healing after complete anterior cruciate ligament injury.
Kano T, Minegish Y, Terada H, Takasu C, Kojima T, Oka Y, Kawabata S, Shimada N, Morishita Y, Murata K, Kanemura N
Experimental biology and medicine (Maywood, N.J.) 2023 Oct;248(20):1895-1904
Experimental biology and medicine (Maywood, N.J.) 2023 Oct;248(20):1895-1904
The crosstalk between M1 macrophage polarization and energy metabolism disorder contributes to polystyrene nanoplastics-triggered testicular inflammation.
Li S, Liu L, Luo G, Yuan Y, Hu D, Xiao F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Oct;180:114002
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Oct;180:114002
Targeting and repolarizing M2-like tumor-associated macrophage-mediated MR imaging and tumor immunotherapy by biomimetic nanoparticles.
Chong L, Jiang YW, Wang D, Chang P, Xu K, Li J
Journal of nanobiotechnology 2023 Oct 31;21(1):401
Journal of nanobiotechnology 2023 Oct 31;21(1):401
Sulforaphene Inhibits Periodontitis through Regulating Macrophage Polarization via Upregulating Dendritic Cell Immunoreceptor.
Liao Y, Yan Q, Cheng T, Yao H, Zhao Y, Fu D, Ji Y, Shi B
Journal of agricultural and food chemistry 2023 Oct 25;71(42):15538-15552
Journal of agricultural and food chemistry 2023 Oct 25;71(42):15538-15552
Oroxylin a promoted apoptotic extracellular vesicles transfer of glycolytic kinases to remodel immune microenvironment in hepatocellular carcinoma model.
Wang P, Cao J, Feng Z, Tang Y, Han X, Mao T, Li S, Guo Q, Ke X, Zhang X
European journal of pharmacology 2023 Oct 15;957:176037
European journal of pharmacology 2023 Oct 15;957:176037
ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.
Zhang Y, Wang Y, Li J, Li C, Liu W, Long X, Wang Z, Zhao R, Ge J, Shi B
Shock (Augusta, Ga.) 2023 Oct 1;60(4):573-584
Shock (Augusta, Ga.) 2023 Oct 1;60(4):573-584
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis.
Xiao Y, Yuan Y, Yang Y, Liu B, Ding Z, Luo J, Chen S, Yu L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Nov;72(10-11):1941-1955
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Nov;72(10-11):1941-1955
Local administration of liposomal-based Plekhf1 gene therapy attenuates pulmonary fibrosis by modulating macrophage polarization.
Yan L, Hou C, Liu J, Wang Y, Zeng C, Yu J, Zhou T, Zhou Q, Duan S, Xiong W
Science China. Life sciences 2023 Nov;66(11):2571-2586
Science China. Life sciences 2023 Nov;66(11):2571-2586
Thermal/ultrasound-triggered release of liposomes loaded with Ganoderma applanatum polysaccharide from microbubbles for enhanced tumour ablation.
Yuan J, Ding L, Han L, Pang L, Zhang P, Yang X, Liu H, Zheng M, Zhang Y, Luo W
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:84-100
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:84-100
Localized delivery of anti-inflammatory agents using extracellular matrix-nanostructured lipid carriers hydrogel promotes cardiac repair post-myocardial infarction.
Wang X, Shi H, Huang S, Zhang Y, He X, Long Q, Qian B, Zhong Y, Qi Z, Zhao Q, Ye X
Biomaterials 2023 Nov;302:122364
Biomaterials 2023 Nov;302:122364
Dipeptidyl peptidase 4 inhibitor reduces tumor-associated macrophages and enhances anti-PD-L1-mediated tumor suppression in non-small cell lung cancer.
Zuo B, Li T, Liu X, Wang S, Cheng J, Liu X, Cui W, Shi H, Ling C
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Nov;25(11):3188-3202
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Nov;25(11):3188-3202
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
Li M, Che N, Liu X, Xuan Y, Jin Y
Biochemical pharmacology 2023 Nov;217:115838
Biochemical pharmacology 2023 Nov;217:115838
In vitro acne disease model from inertial focusing effect for studying the interactions between sebocyte glands and macrophages.
Tang T, Xu Y, Wang L, Zhang P
Biotechnology journal 2023 Nov;18(11):e2300108
Biotechnology journal 2023 Nov;18(11):e2300108
Koumine ameliorates neuroinflammation by regulating microglia polarization via activation of Nrf2/HO-1 pathway.
Wang L, Ding YY, Wu YQ, Zhao C, Wu J, Wang WJ, Meng FH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115608
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115608
Electro-nape-acupuncture regulates the differentiation of microglia through PD-1/PD-L1 reducing secondary brain injury in acute phase intracerebral hemorrhage rats.
Liu Y, Zheng S, Zhang X, Guo W, Du R, Yuan H, Zhang L, Cui H
Brain and behavior 2023 Nov;13(11):e3229
Brain and behavior 2023 Nov;13(11):e3229
Roflumilast attenuates neuroinflammation post retinal ischemia/reperfusion injury by regulating microglia phenotype via the Nrf2/STING/NF-κB pathway.
Guo Y, Ou C, Zhang N, Liu Q, Xiong K, Yu J, Cheng H, Chen L, Ma M, Xu J, Wu J
International immunopharmacology 2023 Nov;124(Pt B):110952
International immunopharmacology 2023 Nov;124(Pt B):110952
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Yan S, Ding J, Wang Z, Zhang F, Li J, Zhang Y, Wu S, Yang L, Pang X, Zhang Y, Yang J
International immunopharmacology 2023 Nov;124(Pt A):110840
International immunopharmacology 2023 Nov;124(Pt A):110840
Silk Acid as an Implantable Biomaterial for Tissue Regeneration.
Sun Z, Huang R, Lyu H, Yu X, Wang W, Li J, Lu X, Guo C
Advanced healthcare materials 2023 Nov;12(28):e2301439
Advanced healthcare materials 2023 Nov;12(28):e2301439
Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury.
Ling X, Wei S, Ling D, Cao S, Chang R, Wang Q, Yuan Z
Cellular & molecular biology letters 2023 Nov 9;28(1):91
Cellular & molecular biology letters 2023 Nov 9;28(1):91
SCH 644343 alleviates ischemic stroke-induced neuroinflammation by promoting microglial polarization via the IL-4/SREBP-1 signaling pathway.
Huang Y, Li K, Dai Q, Pang H, Xu Z, Luo X, Liu L
European journal of pharmacology 2023 Nov 5;958:176033
European journal of pharmacology 2023 Nov 5;958:176033
Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization.
Yang Y, Gao ZF, Hou GG, Meng QG, Hou Y
European journal of medicinal chemistry 2023 Nov 5;259:115688
European journal of medicinal chemistry 2023 Nov 5;259:115688
Four-dimensional hydrogel dressing adaptable to the urethral microenvironment for scarless urethral reconstruction.
Hua Y, Wang K, Huo Y, Zhuang Y, Wang Y, Fang W, Sun Y, Zhou G, Fu Q, Cui W, Zhang K
Nature communications 2023 Nov 22;14(1):7632
Nature communications 2023 Nov 22;14(1):7632
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Hu WM, Li M, Ning JZ, Tang YQ, Song TB, Li LZ, Zou F, Cheng F, Yu WM
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6.
Luo Y, Li Y, He L, Tu H, Lin X, Zhao F, Huang Y, Wen M, Wang L, Yang Z
Chinese medicine 2023 Nov 2;18(1):143
Chinese medicine 2023 Nov 2;18(1):143
TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling.
Su W, Gao W, Zhang R, Wang Q, Li L, Bu Q, Xu Z, Liu Z, Wang M, Zhu Y, Wu G, Zhou H, Wang X, Lu L
JHEP reports : innovation in hepatology 2023 May;5(5):100695
JHEP reports : innovation in hepatology 2023 May;5(5):100695
Silk Fibroin and Sericin Differentially Potentiate the Paracrine and Regenerative Functions of Stem Cells Through Multiomics Analysis.
Zhang Y, Sheng R, Chen J, Wang H, Zhu Y, Cao Z, Zhao X, Wang Z, Liu C, Chen Z, Zhang P, Kuang B, Zheng H, Shen C, Yao Q, Zhang W
Advanced materials (Deerfield Beach, Fla.) 2023 May;35(20):e2210517
Advanced materials (Deerfield Beach, Fla.) 2023 May;35(20):e2210517
miR-26a-5p alleviates CFA-induced chronic inflammatory hyperalgesia through Wnt5a/CaMKII/NFAT signaling in mice.
Lu Y, Liu M, Guo X, Wang P, Zeng F, Wang H, Tang J, Qin Z, Tao T
CNS neuroscience & therapeutics 2023 May;29(5):1254-1271
CNS neuroscience & therapeutics 2023 May;29(5):1254-1271
Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects.
Li S, Zhang L, Liu C, Kim J, Su K, Chen T, Zhao L, Lu X, Zhang H, Cui Y, Cui X, Yuan F, Pan H
Bioactive materials 2023 May;23:101-117
Bioactive materials 2023 May;23:101-117
Biomimetic oxygen-boosted hybrid membrane nanovesicles as the treatment strategy for ischemic stroke with the concept of the neurovascular unit.
Liu X, Geng X, Shi Y, Liang J, Zhao L
Biomaterials advances 2023 May;148:213379
Biomaterials advances 2023 May;148:213379
Methionine enkephalin suppresses lung cancer metastasis by regulating the polarization of tumor-associated macrophages and the distribution of myeloid-derived suppressor cells in the tumor microenvironment and inhibiting epithelial-mesenchymal transition.
Zhang S, Geng J, Shan F, Shan Y, Griffin N, Wu B, Wang X
International immunopharmacology 2023 May;118:110064
International immunopharmacology 2023 May;118:110064
Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis.
Yao Z, Qi W, Zhang H, Zhang Z, Liu L, Shao Y, Zeng H, Yin J, Pan H, Guo X, Liu A, Cai D, Bai X, Zhang H
eLife 2023 May 5;12
eLife 2023 May 5;12
Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma.
Lin H, Fu L, Li P, Zhu J, Xu Q, Wang Y, Mumin MA, Zhou X, Chen Y, Shu G, Yao G, Chen M, Lu J, Zhang L, Liu Y, Zhao Y, Bao J, Chen W, Luo J, Li X, Chen Z, Cao J
Journal of translational medicine 2023 May 23;21(1):343
Journal of translational medicine 2023 May 23;21(1):343
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Lu Y, Zhang H, Pan H, Zhang Z, Zeng H, Xie H, Yin J, Tang W, Lin R, Zeng C, Cai D
Journal of translational medicine 2023 May 22;21(1):339
Journal of translational medicine 2023 May 22;21(1):339
A smart pathogen detector engineered from intracellular hydrogelation of DNA-decorated macrophages.
Gui Y, Zeng Y, Chen B, Yang Y, Ma J, Li C
Nature communications 2023 May 22;14(1):2927
Nature communications 2023 May 22;14(1):2927
Loss of AKAP12 aggravates rheumatoid arthritis-like symptoms and cardiac damage in collagen-induced arthritis mice.
Ni Y, Cao J, Yuan J, Ning X
Experimental animals 2023 May 17;72(2):242-252
Experimental animals 2023 May 17;72(2):242-252
Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis.
Gao Y, Yuan Y, Wen S, Chen Y, Zhang Z, Feng Y, Jiang B, Ma S, Hu R, Fang C, Ruan X, Yuan Y, Fang X, Luo C, Meng Z, Wang X, Guo X
Oncogenesis 2023 May 15;12(1):26
Oncogenesis 2023 May 15;12(1):26
Exploring the effect of Er miao San-containing serum on macrophage polarization through miR-33/NLRP3 pathway.
Liu M, Wang J, Chen S, Meng X, Cheng Z, Wang J, Tan Y, Su W, Lu Z, Zhang M, Jia X
Journal of ethnopharmacology 2023 May 10;307:116178
Journal of ethnopharmacology 2023 May 10;307:116178
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
Moderate Low UVB Irradiation Modulates Tumor-associated Macrophages and Dendritic Cells and Promotes Antitumor Immunity in Tumor-bearing Mice.
Park G, Cui YH, Yang S, Sun M, Wilkinson E, Li H, Zhang YB, Chen J, Bissonnette M, Lin W, He YY
Photochemistry and photobiology 2023 Mar;99(2):850-856
Photochemistry and photobiology 2023 Mar;99(2):850-856
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Wang Y, Yang X, Cao Y, Li X, Xu R, Yan J, Guo Z, Sun S, Sun X, Wu Y
Heliyon 2023 Mar;9(3):e14475
Heliyon 2023 Mar;9(3):e14475
γ-Glutamylcysteine rescues mice from TNBS-driven inflammatory bowel disease through regulating macrophages polarization.
Zhou J, Yan X, Bi X, Lu S, Liu X, Yang C, Shi Y, Luo L, Yin Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Mar;72(3):603-621
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Mar;72(3):603-621
miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.
Cao ZR, Zheng WX, Jiang YX, Chai H, Gong JH, Zhao MJ, Yan P, Liu YY, Liu XY, Huang ZT, Yang H, Peng DD, Zong KZ, Wu ZJ
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023 Mar;23(3):336-352
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023 Mar;23(3):336-352
Cadmium contributes to atherosclerosis by affecting macrophage polarization.
Wan Y, Mo L, Huang H, Mo L, Zhu W, Li W, Yang G, Chen L, Wu Y, Song J, Yang X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113603
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113603
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Gou Y, Wang H, Wang T, Wang H, Wang B, Jiao N, Yu Y, Cao Y, Wang H, Zhang Z
Immunology 2023 Mar;168(3):389-402
Immunology 2023 Mar;168(3):389-402
Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma.
Rajendran S, Hu Y, Canella A, Peterson C, Gross A, Cam M, Nazzaro M, Haffey A, Serin-Harmanci A, Distefano R, Nigita G, Wang W, Kreatsoulas D, Li Z, Sepeda JA, Sas A, Hester ME, Miller KE, Elemento O, Roberts RD, Holland EC, Rao G, Mardis ER, Rajappa P
Cell reports 2023 Mar 28;42(3):112197
Cell reports 2023 Mar 28;42(3):112197
Superior protective effects of PGE2 priming mesenchymal stem cells against LPS-induced acute lung injury (ALI) through macrophage immunomodulation.
Hezam K, Wang C, Fu E, Zhou M, Liu Y, Wang H, Zhu L, Han Z, Han ZC, Chang Y, Li Z
Stem cell research & therapy 2023 Mar 22;14(1):48
Stem cell research & therapy 2023 Mar 22;14(1):48
Caffeic Acid Phenethyl Ester Suppresses Oxidative Stress and Regulates M1/M2 Microglia Polarization via Sirt6/Nrf2 Pathway to Mitigate Cognitive Impairment in Aged Mice following Anesthesia and Surgery.
Wang Y, Cai Z, Zhan G, Li X, Li S, Wang X, Li S, Luo A
Antioxidants (Basel, Switzerland) 2023 Mar 13;12(3)
Antioxidants (Basel, Switzerland) 2023 Mar 13;12(3)
Mild treadmill exercise inhibits cartilage degeneration via macrophages in an osteoarthritis mouse model.
Oka Y, Murata K, Ozone K, Minegishi Y, Kano T, Shimada N, Kanemura N
Osteoarthritis and cartilage open 2023 Jun;5(2):100359
Osteoarthritis and cartilage open 2023 Jun;5(2):100359
Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by microRNA-193a-3p-dependent regulation of plasminogen activator urokinase.
Zhang T, Yu H, Bai Y, Song J, Chen J, Li Y, Cui Y
Immunopharmacology and immunotoxicology 2023 Jun;45(3):355-369
Immunopharmacology and immunotoxicology 2023 Jun;45(3):355-369
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain.
Gu C, Chen M, Li X, Geng D, Wang C
Molecular medicine reports 2023 Jun;27(6)
Molecular medicine reports 2023 Jun;27(6)
Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis.
Wang J, Hu D, Chen Q, Liu T, Zhou X, Xu Y, Zhou H, Gu D, Gao C
Materials today. Bio 2023 Jun;20:100679
Materials today. Bio 2023 Jun;20:100679
Reversing inflammatory microenvironment by a single intra-articular injection of multi-stimulus responsive lipogel to relieve rheumatoid arthritis and promote joint repair.
Tao J, Yang P, Gao M, Zhang F, Wu Y, Jiang Y, Ning Y, Li Z, Ai F
Materials today. Bio 2023 Jun;20:100622
Materials today. Bio 2023 Jun;20:100622
Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells.
Sheng R, Liu J, Zhang W, Luo Y, Chen Z, Chi J, Mo Q, Wang M, Sun Y, Liu C, Zhang Y, Zhu Y, Kuang B, Yan C, Liu H, Backman LJ, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2206814
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2206814
Lycopene ameliorates islet function and down-regulates the TLR4/MyD88/NF-κB pathway in diabetic mice and Min6 cells.
Liu Y, Tian Y, Dai X, Liu T, Zhang Y, Wang S, Shi H, Yin J, Xu T, Zhu R, Zhang Y, Zhao D, Gao S, Wang XD, Wang L, Zhang D
Food & function 2023 Jun 6;14(11):5090-5104
Food & function 2023 Jun 6;14(11):5090-5104
ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression.
Zhang Y, Wang W, Min J, Liu S, Wang Q, Wang Y, Xiao Y, Li X, Zhou Z, Liu S
Cell reports 2023 Jun 27;42(6):112654
Cell reports 2023 Jun 27;42(6):112654
Disturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice.
Xu J, Yang C, Zeng S, Wang X, Yang P, Qin L
Journal of neuroinflammation 2023 Jun 26;20(1):150
Journal of neuroinflammation 2023 Jun 26;20(1):150
Determining the chemical profile of Caragana jubata (Pall.) Poir. by UPLC-QTOF-MS analysis and evaluating its anti-ischemic stroke effects.
Zhao D, Chen X, Wang R, Pang H, Wang J, Liu L
Journal of ethnopharmacology 2023 Jun 12;309:116275
Journal of ethnopharmacology 2023 Jun 12;309:116275
Tissue-resident CXCR4(+) macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.
Liao Z, Ye L, Li T, Jin X, Lin X, Fei Q, Zhang H, Shi S, Yu X, Jin K, Wu W
International journal of cancer 2023 Jun 1;152(11):2396-2409
International journal of cancer 2023 Jun 1;152(11):2396-2409
Medical Prospect of Melatonin in the Intervertebral Disc Degeneration through Inhibiting M1-Type Macrophage Polarization via SIRT1/Notch Signaling Pathway.
Dou X, Luo Q, Xie L, Zhou X, Song C, Liu M, Liu X, Ma Y, Liu X
Biomedicines 2023 Jun 1;11(6)
Biomedicines 2023 Jun 1;11(6)
High-intensity interval training in the form of isometric contraction improves fatigue resistance in dystrophin-deficient muscle.
Yamauchi N, Tamai K, Kimura I, Naito A, Tokuda N, Ashida Y, Motohashi N, Aoki Y, Yamada T
The Journal of physiology 2023 Jul;601(14):2917-2933
The Journal of physiology 2023 Jul;601(14):2917-2933
UCHL1 aggravates skin fibrosis through an IGF-1-induced Akt/mTOR/HIF-1α pathway in keloid.
Guo C, Liang L, Zheng J, Xie Y, Qiu X, Tan G, Huang J, Wang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jul;37(7):e23015
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jul;37(7):e23015
Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury.
Lv H, Jia S, Sun Y, Pang M, Lv E, Li X, Meng Q, Wang Y
Brain research bulletin 2023 Jul;199:110660
Brain research bulletin 2023 Jul;199:110660
Methylene blue targets PHD3 expression in murine microglia to mitigate lipopolysaccharide-induced neuroinflammation and neurocognitive impairments.
Ou G, Che J, Dong J, Deng Y, Jiang X, Sun Y, He Z, Chen W, Zhang J
International immunopharmacology 2023 Jul;120:110349
International immunopharmacology 2023 Jul;120:110349
DDIT3 aggravates pulpitis by modulating M1 polarization through EGR1 in macrophages.
Wang Y, He Y, Dong W, Jia M, Yang C, Wang J
International immunopharmacology 2023 Jul;120:110328
International immunopharmacology 2023 Jul;120:110328
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Sun W, Wang Q, Zhang R, Zhang N
Food & function 2023 Jul 31;14(15):7247-7269
Food & function 2023 Jul 31;14(15):7247-7269
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Wang K, Zhu K, Zhu Z, Shao F, Qian R, Wang C, Dong H, Li Y, Gao Z, Zhao J
Journal of nanobiotechnology 2023 Jul 17;21(1):227
Journal of nanobiotechnology 2023 Jul 17;21(1):227
Sublethal necroptosis signaling promotes inflammation and liver cancer.
Vucur M, Ghallab A, Schneider AT, Adili A, Cheng M, Castoldi M, Singer MT, Büttner V, Keysberg LS, Küsgens L, Kohlhepp M, Görg B, Gallage S, Barragan Avila JE, Unger K, Kordes C, Leblond AL, Albrecht W, Loosen SH, Lohr C, Jördens MS, Babler A, Hayat S, Schumacher D, Koenen MT, Govaere O, Boekschoten MV, Jörs S, Villacorta-Martin C, Mazzaferro V, Llovet JM, Weiskirchen R, Kather JN, Starlinger P, Trauner M, Luedde M, Heij LR, Neumann UP, Keitel V, Bode JG, Schneider RK, Tacke F, Levkau B, Lammers T, Fluegen G, Alexandrov T, Collins AL, Nelson G, Oakley F, Mann DA, Roderburg C, Longerich T, Weber A, Villanueva A, Samson AL, Murphy JM, Kramann R, Geisler F, Costa IG, Hengstler JG, Heikenwalder M, Luedde T
Immunity 2023 Jul 11;56(7):1578-1595.e8
Immunity 2023 Jul 11;56(7):1578-1595.e8
MCP-1-Loaded Poly(l-lactide-co-caprolactone) Fibrous Films Modulate Macrophage Polarization toward an Anti-inflammatory Phenotype and Improve Angiogenesis.
Cheng C, Li H, Liu J, Wu L, Fang Z, Xu G
ACS biomaterials science & engineering 2023 Jul 10;9(7):4356-4367
ACS biomaterials science & engineering 2023 Jul 10;9(7):4356-4367
Dual delivery of an NF-κB inhibitor and IL-10 through supramolecular hydrogels polarizes macrophages and promotes cardiac repair after myocardial infarction.
Wang D, Hu Y, Zhang L, Cai H, Wang Y, Zhang Y
Acta biomaterialia 2023 Jul 1;164:111-123
Acta biomaterialia 2023 Jul 1;164:111-123
Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes.
Wu F, Yin YY, Fan WH, Zhai Y, Yu MC, Wang D, Pan CQ, Zhao Z, Li GZ, Zhang W
EBioMedicine 2023 Jan;87:104410
EBioMedicine 2023 Jan;87:104410
[Periodontitis Promotes the Progression of Oral Squamous Cell Carcinoma by Inducing Macrophage M2 Polarization].
Li J, Wei W, Tang BY, Li Y
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2023 Jan;54(1):83-90
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2023 Jan;54(1):83-90
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
Hao B, Zhang Z, Lu Z, Xiong J, Fan T, Song C, He R, Zhang L, Pan S, Li D, Meng H, Lin W, Luo B, Yang J, Li N, Geng Q
Translational oncology 2023 Jan;27:101568
Translational oncology 2023 Jan;27:101568
Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
Hui Y, Xu Z, Li J, Kuang L, Zhong Y, Tang Y, Wei J, Zhou H, Zheng T
Metabolism: clinical and experimental 2023 Jan;138:155340
Metabolism: clinical and experimental 2023 Jan;138:155340
Chronic docosahexaenoic acid supplementation improves metabolic plasticity in subcutaneous adipose tissue of aged obese female mice.
Félix-Soriano E, Sáinz N, Fernández-Galilea M, Gil-Iturbe E, Celay J, Martínez-Climent JA, Moreno-Aliaga MJ
The Journal of nutritional biochemistry 2023 Jan;111:109153
The Journal of nutritional biochemistry 2023 Jan;111:109153
Exploration of the mechanism by which Huangqi Guizhi Wuwu decoction inhibits Lps-induced inflammation by regulating macrophage polarization based on network pharmacology.
Wang S, Ji T, Wang L, Qu Y, Wang X, Wang W, Lv M, Wang Y, Li X, Jiang P
BMC complementary medicine and therapies 2023 Jan 9;23(1):8
BMC complementary medicine and therapies 2023 Jan 9;23(1):8
SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer.
Gan C, Li M, Lu Y, Peng G, Li W, Wang H, Peng Y, Hu Q, Wei W, Wang F, Liu L, Zhao Q
BMC gastroenterology 2023 Jan 7;23(1):4
BMC gastroenterology 2023 Jan 7;23(1):4
Carrier-Free Immunotherapeutic Nano-Booster with Dual Synergistic Effects Based on Glutaminase Inhibition Combined with Photodynamic Therapy.
Mai Z, Zhong J, Zhang J, Chen G, Tang Y, Ma W, Li G, Feng Z, Li F, Liang XJ, Yang Y, Yu Z
ACS nano 2023 Jan 3;
ACS nano 2023 Jan 3;
Acceleration of Oral Wound Healing under Diabetes Mellitus Conditions Using Bioadhesive Hydrogel.
Sun J, Chen T, Zhao B, Fan W, Shen Y, Wei H, Zhang M, Zheng W, Peng J, Wang J, Wang Y, Fan L, Chu Y, Chen L, Yang C
ACS applied materials & interfaces 2023 Jan 11;15(1):416-431
ACS applied materials & interfaces 2023 Jan 11;15(1):416-431
Perfluorooctane sulfonate promotes atherosclerosis by modulating M1 polarization of macrophages through the NF-κB pathway.
Wang D, Tan Z, Yang J, Li L, Li H, Zhang H, Liu H, Liu Y, Wang L, Li Q, Guo H
Ecotoxicology and environmental safety 2023 Jan 1;249:114384
Ecotoxicology and environmental safety 2023 Jan 1;249:114384
The protective effect of gamma aminobutyric acid B receptor activation on sympathetic nerve remodeling via the regulation of M2 macrophage polarization after myocardial infarction.
Liu Q, Li Y, Shi Y, Tan J, Yan W, Zhang J, Gao P, Yan S
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2023 Feb;42(2):125-135
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2023 Feb;42(2):125-135
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Hu H, Lu X, Huang L, He Y, Liu X, Wang Y, Duan C
Metabolic brain disease 2023 Feb;38(2):699-708
Metabolic brain disease 2023 Feb;38(2):699-708
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.
Li Y, Zhang J, Wang C, Jiang Z, Lai K, Wang Y, Yang G
Acta biomaterialia 2023 Feb;157:108-123
Acta biomaterialia 2023 Feb;157:108-123
T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma.
Wang X, Zhang Q, Zhou J, Xiao Z, Liu J, Deng S, Hong X, Huang W, Cai M, Guo Y, Huang J, Wang Y, Lin L, Zhu K
Journal for immunotherapy of cancer 2023 Feb;11(2)
Journal for immunotherapy of cancer 2023 Feb;11(2)
Effects of magnetically targeted iron oxide@polydopamine-labeled human umbilical cord mesenchymal stem cells in cerebral infarction in mice.
Yan J, Liu T, Li Y, Zhang J, Shi B, Zhang F, Hou X, Zhang X, Cui W, Li J, Yao H, Li X, Gao Y, Jiang J
Aging 2023 Feb 28;15(4):1130-1142
Aging 2023 Feb 28;15(4):1130-1142
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Wang T, Yu M, Li H, Qin S, Ren W, Ma Y, Bo W, Xi Y, Cai M, Tian Z
International journal of molecular sciences 2023 Feb 19;24(4)
International journal of molecular sciences 2023 Feb 19;24(4)
Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer's disease in APP/PS1 mouse.
Wang S, Zhu T, Ni W, Zhou C, Zhou H, Lin L, Hu Y, Sun X, Han J, Zhou Y, Jin G, Zu J, Shi H, Yang X, Zhang Z, Hua F
Alzheimer's research & therapy 2023 Feb 16;15(1):33
Alzheimer's research & therapy 2023 Feb 16;15(1):33
4,4'-Methylene diphenyl diisocyanate exposure induces expression of alternatively activated macrophage-associated markers and chemokines partially through Krüppel-like factor 4 mediated signaling in macrophages.
Lin CC, Law BF, Hettick JM
Xenobiotica; the fate of foreign compounds in biological systems 2023 Dec;53(12):653-669
Xenobiotica; the fate of foreign compounds in biological systems 2023 Dec;53(12):653-669
Bionic peptide scaffold in situ polarization and recruitment of M2 macrophages to promote peripheral nerve regeneration.
Yang P, Peng Y, Dai X, Jie J, Kong D, Gu X, Yang Y
Bioactive materials 2023 Dec;30:85-97
Bioactive materials 2023 Dec;30:85-97
WNT4 promotes macrophage polarization via granulosa cell M-CSF and reduces granulosa cell apoptosis in endometriosis.
Yuan Y, Li Y, Zhao W, Hu Y, Zhou C, Long T, Long L
Cytokine 2023 Dec;172:156400
Cytokine 2023 Dec;172:156400
Ischemic Preconditioning Alleviates Cerebral Ischemia-Reperfusion Injury by Interfering With Glycocalyx.
Zhang YN, Wu Q, Zhang NN, Chen HS
Translational stroke research 2023 Dec;14(6):929-940
Translational stroke research 2023 Dec;14(6):929-940
Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy.
Guo L, Ding J, Zhou W
Acta pharmaceutica Sinica. B 2023 Dec;13(12):5074-5090
Acta pharmaceutica Sinica. B 2023 Dec;13(12):5074-5090
The lncRNA H19/miR-29a-3p/SNIP1/c-myc regulatory axis is involved in pulmonary fibrosis induced by Nd2O3.
Bu N, Wang S, Ma Y, Xia H, Zhao Y, Shi X, Liu Q, Wang S, Gao Y
Toxicological sciences : an official journal of the Society of Toxicology 2023 Dec 21;197(1):27-37
Toxicological sciences : an official journal of the Society of Toxicology 2023 Dec 21;197(1):27-37
Copine 1 predicts poor clinical outcomes by promoting M2 macrophage activation in ovarian cancer.
Sheng B, Zhao B, Dong Y, Zhang J, Wu S, Ji H, Zhu X
Carcinogenesis 2023 Dec 15;44(10-11):748-759
Carcinogenesis 2023 Dec 15;44(10-11):748-759
Melatonin-pretreated human umbilical cord mesenchymal stem cells improved endometrium regeneration and fertility recovery through macrophage immunomodulation in rats with intrauterine adhesions†.
Qin W, Wang J, Hu Q, Qin R, Ma N, Zheng F, Tian W, Jiang J, Li T, Jin Y, Liao M, Qin A
Biology of reproduction 2023 Dec 11;109(6):918-937
Biology of reproduction 2023 Dec 11;109(6):918-937
Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice.
Laiglesia LM, Escoté X, Sáinz N, Felix-Soriano E, Santamaría E, Collantes M, Fernández-Galilea M, Colón-Mesa I, Martínez-Fernández L, Quesada-López T, Quesada-Vázquez S, Rodríguez-Ortigosa C, Arbones-Mainar JM, Valverde ÁM, Martínez JA, Dalli J, Herrero L, Lorente-Cebrián S, Villarroya F, Moreno-Aliaga MJ
Molecular metabolism 2023 Aug;74:101749
Molecular metabolism 2023 Aug;74:101749
Scutellarin Acts via MAPKs Pathway to Promote M2 Polarization of Microglial Cells.
Chen HL, Yang L, Zhang XL, Jia QY, Duan ZD, Li JJ, Zheng LY, Liu TT, Qi Z, Yuan Y, Wu CY
Molecular neurobiology 2023 Aug;60(8):4304-4323
Molecular neurobiology 2023 Aug;60(8):4304-4323
TRAF3/STAT6 axis regulates macrophage polarization and tumor progression.
Shi JH, Liu LN, Song DD, Liu WW, Ling C, Wu FX, Wang TT, Liu B, Cui NP, Qin Y, Ni ZY
Cell death and differentiation 2023 Aug;30(8):2005-2016
Cell death and differentiation 2023 Aug;30(8):2005-2016
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Ge X, Wen H, Fei Y, Xue R, Cheng Z, Li Y, Cai K, Li L, Li M, Luo Z
Biomaterials 2023 Aug;299:122184
Biomaterials 2023 Aug;299:122184
Hollow copper sulfide nanoparticles carrying ISRIB for the sensitized photothermal therapy of breast cancer and brain metastases through inhibiting stress granule formation and reprogramming tumor-associated macrophages.
Tong F, Hu H, Xu Y, Zhou Y, Xie R, Lei T, Du Y, Yang W, He S, Huang Y, Gong T, Gao H
Acta pharmaceutica Sinica. B 2023 Aug;13(8):3471-3488
Acta pharmaceutica Sinica. B 2023 Aug;13(8):3471-3488
KCND2: A prognostic biomarker and regulator of immune function in gastric cancer.
Zhou H, Su D, Chen Y, Zhang Y, Huang P
Cancer medicine 2023 Aug;12(15):16279-16294
Cancer medicine 2023 Aug;12(15):16279-16294
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Tian J, Zhang L, La X, Fan X, Li A, Wu C, An Y, Yan S, Dong X, Wu H, Li Z
Cellular signalling 2023 Aug;108:110719
Cellular signalling 2023 Aug;108:110719
Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts.
Tan Y, Coyle RC, Barrs RW, Silver SE, Li M, Richards DJ, Lin Y, Jiang Y, Wang H, Menick DR, Deleon-Pennell K, Tian B, Mei Y
Science advances 2023 Aug 4;9(31):eadf2898
Science advances 2023 Aug 4;9(31):eadf2898
Constitutive aryl hydrocarbon receptor facilitates the regenerative potential of mouse bone marrow mesenchymal stromal cells.
Huang J, Wang YN, Zhou Y
World journal of stem cells 2023 Aug 26;15(8):807-820
World journal of stem cells 2023 Aug 26;15(8):807-820
Loureirin B protects against cerebral ischemia/reperfusion injury through modulating M1/M2 microglial polarization via STAT6 / NF-kappaB signaling pathway.
Li R, Jia H, Si M, Li X, Ma Z, Zhu Y, Sun W, Zhu F, Luo S
European journal of pharmacology 2023 Aug 15;953:175860
European journal of pharmacology 2023 Aug 15;953:175860
Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.
Ni R, Luo Y, Jiang L, Mao X, Feng Y, Tuersun S, Hu Z, Zhu Y
International journal of biological macromolecules 2023 Aug 1;245:125556
International journal of biological macromolecules 2023 Aug 1;245:125556
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
Niu XH, Liu RH, Lv X, He RL, Lv FZ, Wu SJ, Li XQ, Li L, Lin JF
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
Irisin attenuates acute lung injury by suppressing the pyroptosis of alveolar macrophages.
Han Z, Ma J, Han Y, Yuan G, Jiao R, Meng A
International journal of molecular medicine 2023 Apr;51(4)
International journal of molecular medicine 2023 Apr;51(4)
Melatonin ameliorates neurological deficits through MT2/IL-33/ferritin H signaling-mediated inhibition of neuroinflammation and ferroptosis after traumatic brain injury.
Gao Y, Wang T, Cheng Y, Wu Y, Zhu L, Gu Z, Wu Y, Cai L, Wu Y, Zhang Y, Gao C, Li L, Li J, Li Q, Wang Z, Wang Y, Wang F, Luo C, Tao L
Free radical biology & medicine 2023 Apr;199:97-112
Free radical biology & medicine 2023 Apr;199:97-112
Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis.
Wo B, Du C, Yang Y, Qi H, Liang Z, He C, Yao F, Li X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114363
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114363
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
Chen S, Lu K, Hou Y, You Z, Shu C, Wei X, Wu T, Shi N, Zhang G, Wu J, Chen S, Zhang L, Li W, Zhang D, Ju S, Chen M, Xu B
Journal for immunotherapy of cancer 2023 Apr;11(4)
Journal for immunotherapy of cancer 2023 Apr;11(4)
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
Zheng Z, Cao F, Ding YX, Lu JD, Fu YQ, Liu L, Guo YL, Liu S, Sun HC, Cui YQ, Li F
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620
Oleoylethanolamide Protects against Acute Ischemic Stroke by Promoting PPARα-Mediated Microglia/Macrophage M2 Polarization.
Li Y, Zhang Y, Wang Q, Wu C, Du G, Yang L
Pharmaceuticals (Basel, Switzerland) 2023 Apr 20;16(4)
Pharmaceuticals (Basel, Switzerland) 2023 Apr 20;16(4)
Electrospun Polycaprolactone (PCL)-Amnion Nanofibrous Membrane Promotes Nerve Regeneration and Prevents Fibrosis in a Rat Sciatic Nerve Transection Model.
Bai J, Liu C, Kong L, Tian S, Yu K, Tian D
Frontiers in surgery 2022;9:842540
Frontiers in surgery 2022;9:842540
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.
Zhang M, Wang XL, Shi H, Meng LQ, Quan HF, Yan L, Yang HF, Peng XD
Journal of immunology research 2022;2022:9313436
Journal of immunology research 2022;2022:9313436
Macrophage Extracellular Traps Exacerbate Secondary Spinal Cord Injury by Modulating Macrophage/Microglia Polarization via LL37/P2X7R/NF-κB Signaling Pathway.
Zhang C, Guo D, Qiao H, Li J, Li J, Yang Y, Chang S, Li F, Wang D, Li H, He X, Wang F
Oxidative medicine and cellular longevity 2022;2022:9197940
Oxidative medicine and cellular longevity 2022;2022:9197940
The Role of Microglia/Macrophages Activation and TLR4/NF-κB/MAPK Pathway in Distraction Spinal Cord Injury-Induced Inflammation.
Liang W, Han B, Hai Y, Liu Y, Liu X, Yang J, Sun D, Yin P
Frontiers in cellular neuroscience 2022;16:926453
Frontiers in cellular neuroscience 2022;16:926453
LncRNA AC099850.3 promotes hepatocellular carcinoma proliferation and invasion through PRR11/PI3K/AKT axis and is associated with patients prognosis.
Zhong F, Liu S, Hu D, Chen L
Journal of Cancer 2022;13(3):1048-1060
Journal of Cancer 2022;13(3):1048-1060
Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression.
Yu M, Yang Y, Zhao H, Li M, Chen J, Wang B, Xiao T, Huang C, Zhao H, Zhou W, Zhang JV
Frontiers in pharmacology 2022;13:985618
Frontiers in pharmacology 2022;13:985618
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Li L, Deng S, Liu M, Yang M, Li J, Liu T, Zhang T, Zhao Y, He M, Wu D, Xu Y
Frontiers in pharmacology 2022;13:956402
Frontiers in pharmacology 2022;13:956402
Characterization of Fatty Acid Metabolism-Related Genes Landscape for Predicting Prognosis and Aiding Immunotherapy in Glioma Patients.
Jiang F, Luo F, Zeng N, Mao Y, Tang X, Wang J, Hu Y, Wu C
Frontiers in immunology 2022;13:902143
Frontiers in immunology 2022;13:902143
CCR5 as a Prognostic Factor in Lower-Grade Glioma is Involved in the Remodeling of the Tumor Microenvironment.
Wang F, Tao Z, Tian Z, Jin J, Dong J, Dai Y, Yu W, Tang B, Hu S
Frontiers in genetics 2022;13:874896
Frontiers in genetics 2022;13:874896
Digital Spatial Profiling of Individual Glomeruli From Patients With Anti-Neutrophil Cytoplasmic Autoantibody-Associated Glomerulonephritis.
Ye L, Liu Y, Zhu X, Duan T, Wang C, Fu X, Song P, Yuan S, Liu H, Sun L, Liu F, Lee K, He JC, Chen A
Frontiers in immunology 2022;13:831253
Frontiers in immunology 2022;13:831253
Identification and validation of a 17-gene signature to improve the survival prediction of gliomas.
Tong S, Xia M, Xu Y, Sun Q, Ye L, Cai J, Ye Z, Tian D
Frontiers in immunology 2022;13:1000396
Frontiers in immunology 2022;13:1000396
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Peng P, Zhu H, Liu D, Chen Z, Zhang X, Guo Z, Dong M, Wan L, Zhang P, Liu G, Zhang S, Dong F, Hu F, Cheng F, Huang S, Guo D, Zhang B, Yu X, Wan F
Theranostics 2022;12(9):4221-4236
Theranostics 2022;12(9):4221-4236
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231
Theranostics 2022;12(5):2205-2231
Heparin/Collagen-REDV Modification of Expanded Polytetrafluoroethylene Improves Regional Anti-thrombosis and Reduces Foreign Body Reactions in Local Tissues.
Shan Y, Chen G, Shi Q, Huang J, Mi Y, Zhang W, Zhang H, Jia B
Frontiers in bioengineering and biotechnology 2022;10:916931
Frontiers in bioengineering and biotechnology 2022;10:916931
Adaptive Gelatin Microspheres Enhanced Stem Cell Delivery and Integration With Diabetic Wounds to Activate Skin Tissue Regeneration.
Shi M, Gao Y, Lee L, Song T, Zhou J, Yan L, Li Y
Frontiers in bioengineering and biotechnology 2022;10:813805
Frontiers in bioengineering and biotechnology 2022;10:813805
Vascular endothelial growth factor attenuates neointimal hyperplasia of decellularized small-diameter vascular grafts by modulating the local inflammatory response.
Xie X, Wu Q, Liu Y, Chen C, Chen Z, Xie C, Song M, Jiang Z, Qi X, Liu S, Tang Z, Wu Z
Frontiers in bioengineering and biotechnology 2022;10:1066266
Frontiers in bioengineering and biotechnology 2022;10:1066266
Osteoimmunity-Regulating Biomimetically Hierarchical Scaffold for Augmented Bone Regeneration.
Zhang J, Tong D, Song H, Ruan R, Sun Y, Lin Y, Wang J, Hou L, Dai J, Ding J, Yang H
Advanced materials (Deerfield Beach, Fla.) 2022 Sep;34(36):e2202044
Advanced materials (Deerfield Beach, Fla.) 2022 Sep;34(36):e2202044
Hirudin alleviates acute ischemic stroke by inhibiting NLRP3 inflammasome-mediated neuroinflammation: In vivo and in vitro approaches.
Li WQ, Qin ZS, Chen S, Cheng D, Yang SC, Choi YMM, Chu B, Zhou WH, Zhang ZJ
International immunopharmacology 2022 Sep;110:108967
International immunopharmacology 2022 Sep;110:108967
miR-146a-5p enhances embryo survival in unexplained recurrent spontaneous abortion by promoting M2 polarization of decidual macrophages.
Ye HX, Liao GN, Dong YJ, Li L, Wang XM, Shu J, Zheng Q, Jia Y
International immunopharmacology 2022 Sep;110:108930
International immunopharmacology 2022 Sep;110:108930
Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn's colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling.
Ye Y, Zhang X, Su D, Ren Y, Cheng F, Yao Y, Shi G, Ji Y, Chen S, Shi P, Dai L, Su X, Deng H
Stem cell research & therapy 2022 Sep 8;13(1):465
Stem cell research & therapy 2022 Sep 8;13(1):465
Macrophage-derived extracellular vesicles regulate follicular activation and improve ovarian function in old mice by modulating local environment.
Xiao Y, Peng X, Peng Y, Zhang C, Liu W, Yang W, Dou X, Jiang Y, Wang Y, Yang S, Xiang W, Wu T, Li J
Clinical and translational medicine 2022 Oct;12(10):e1071
Clinical and translational medicine 2022 Oct;12(10):e1071
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
Chen S, Qian S, Zhang L, Pan X, Qu F, Yu Y, Gu Z, Cui X, Shen H
International immunopharmacology 2022 Oct;111:109139
International immunopharmacology 2022 Oct;111:109139
Biomechanically-Adapted Immunohydrogels Reconstructing Myelin Sheath for Peripheral Nerve Regeneration.
Wang Y, Yan Z, Liu W, Liu C, Xu N, Wu Y, Sun F, Wang X, Qian Y, Jiang L, Sun X
Advanced healthcare materials 2022 Oct;11(20):e2201596
Advanced healthcare materials 2022 Oct;11(20):e2201596
A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.
Zheng Z, Lei C, Liu H, Jiang M, Zhou Z, Zhao Y, Yu CY, Wei H
Advanced healthcare materials 2022 Oct;11(19):e2200990
Advanced healthcare materials 2022 Oct;11(19):e2200990
Parthenolide modulates cerebral ischemia-induced microglial polarization and alleviates neuroinflammatory injury via the RhoA/ROCK pathway.
Zhang Y, Miao L, Peng Q, Fan X, Song W, Yang B, Zhang P, Liu G, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154373
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154373
Poria cocos polysaccharides rescue pyroptosis-driven gut vascular barrier disruption in order to alleviates non-alcoholic steatohepatitis.
Ye H, Ma S, Qiu Z, Huang S, Deng G, Li Y, Xu S, Yang M, Shi H, Wu C, Li M, Zhang J, Zhang F, Qin M, Huang H, Zeng Z, Wang M, Chen Y, Lin H, Gao Z, Cai M, Song Y, Gong S, Gao L
Journal of ethnopharmacology 2022 Oct 5;296:115457
Journal of ethnopharmacology 2022 Oct 5;296:115457
Ultrasound-augmented anti-inflammatory exosomes for targeted therapy in rheumatoid arthritis.
Tang Y, Wu Z, Guo R, Huang J, Rong X, Zhu B, Wang L, Ma L, Cheng C, Qiu L
Journal of materials chemistry. B 2022 Oct 5;10(38):7862-7874
Journal of materials chemistry. B 2022 Oct 5;10(38):7862-7874
Esomeprazole inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia-reperfusion injury.
Zhou G, Peng Y, Guo M, Qu C, Luo S, Jiang Y, Chen D, Wang X, Guo Y
Biochemical and biophysical research communications 2022 Oct 30;627:84-90
Biochemical and biophysical research communications 2022 Oct 30;627:84-90
Oral Microbiota from Periodontitis Promote Oral Squamous Cell Carcinoma Development via γδ T Cell Activation.
Wei W, Li J, Shen X, Lyu J, Yan C, Tang B, Ma W, Xie H, Zhao L, Cheng L, Deng Y, Li Y
mSystems 2022 Oct 26;7(5):e0046922
mSystems 2022 Oct 26;7(5):e0046922
Melatonin-Primed MSCs Alleviate Intrauterine Adhesions by Affecting MSC-Expressed Galectin-3 on Macrophage Polarization.
Jiang Q, Li J, Pan Y, Wang J, Yang J, Shen S, Hou Y
Stem cells (Dayton, Ohio) 2022 Oct 21;40(10):919-931
Stem cells (Dayton, Ohio) 2022 Oct 21;40(10):919-931
PARP-inhibition reprograms macrophages toward an anti-tumor phenotype.
Wang L, Wang D, Sonzogni O, Ke S, Wang Q, Thavamani A, Batalini F, Stopka SA, Regan MS, Vandal S, Tian S, Pinto J, Cyr AM, Bret-Mounet VC, Baquer G, Eikesdal HP, Yuan M, Asara JM, Heng YJ, Bai P, Agar NYR, Wulf GM
Cell reports 2022 Oct 11;41(2):111462
Cell reports 2022 Oct 11;41(2):111462
Curcumin attenuates cadmium-induced atherosclerosis by regulating trimethylamine-N-oxide synthesis and macrophage polarization through remodeling the gut microbiota.
Zhang J, Ou C, Chen M
Ecotoxicology and environmental safety 2022 Oct 1;244:114057
Ecotoxicology and environmental safety 2022 Oct 1;244:114057
Fecal microbiota transplantation from young donor mice improves ovarian function in aged mice.
Xu L, Zhang Q, Dou X, Wang Y, Wang J, Zhou Y, Liu X, Li J
Journal of genetics and genomics = Yi chuan xue bao 2022 Nov;49(11):1042-1052
Journal of genetics and genomics = Yi chuan xue bao 2022 Nov;49(11):1042-1052
Scalable macroporous hydrogels enhance stem cell treatment of volumetric muscle loss.
Eugenis I, Wu D, Hu C, Chiang G, Huang NF, Rando TA
Biomaterials 2022 Nov;290:121818
Biomaterials 2022 Nov;290:121818
Monocyte Recruitment for Vascular Tissue Regeneration.
Nasiri B, Yi T, Wu Y, Smith RJ Jr, Podder AK, Breuer CK, Andreadis ST
Advanced healthcare materials 2022 Nov;11(22):e2200890
Advanced healthcare materials 2022 Nov;11(22):e2200890
EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis.
Zhang X, Chen C, Ling C, Luo S, Xiong Z, Liu X, Liao C, Xie P, Liu Y, Zhang L, Chen Z, Liu Z, Tang J
Cell death & disease 2022 Nov 7;13(11):934
Cell death & disease 2022 Nov 7;13(11):934
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Jin Y, Zhang Q, Qin X, Liu Z, Li Z, Zhong X, Xia L, He J, Fang B
Journal of nanobiotechnology 2022 Nov 3;20(1):469
Journal of nanobiotechnology 2022 Nov 3;20(1):469
Naringenin promoted spinal microglia M2 polarization in rat model of cancer-induced bone pain via regulating AMPK/PGC-1α signaling axis.
Ge MM, Li DY, Wang L, Zhang LQ, Liu DQ, Tian YK, Ye DW, Liu ZH, Zhou YQ, Yang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112912
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112912
A biomimetic zeolite-based nanoenzyme contributes to neuroprotection in the neurovascular unit after ischaemic stroke via efficient removal of zinc and ROS.
Huang Z, Qian K, Chen J, Qi Y, E Y, Liang J, Zhao L
Acta biomaterialia 2022 May;144:142-156
Acta biomaterialia 2022 May;144:142-156
Facile fabrication of a biocompatible composite gel with sustained release of aspirin for bone regeneration.
Zhang Y, Dou X, Zhang L, Wang H, Zhang T, Bai R, Sun Q, Wang X, Yu T, Wu D, Han B, Deng X
Bioactive materials 2022 May;11:130-139
Bioactive materials 2022 May;11:130-139
Dedicator of Cytokinesis 2 (DOCK2) Silencing Protects Against Cerebral Ischemia/Reperfusion by Modulating Microglia Polarization via the Activation of the STAT6 Signaling Pathway.
Ding S, Cao Y, Lu X, Zhang H, Cong L, Yi T, Xu M, Wang L
Neuroscience 2022 May 21;491:110-121
Neuroscience 2022 May 21;491:110-121
Colorectal Cancer-Derived Small Extracellular Vesicles Promote Tumor Immune Evasion by Upregulating PD-L1 Expression in Tumor-Associated Macrophages.
Yin Y, Liu B, Cao Y, Yao S, Liu Y, Jin G, Qin Y, Chen Y, Cui K, Zhou L, Bian Z, Fei B, Huang S, Huang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Mar;9(9):2102620
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Mar;9(9):2102620
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Kang H, Dong Y, Peng R, Liu H, Guo Q, Song K, Zhu M, Yu K, Wu W, Li F
Biochemical pharmacology 2022 Mar;197:114932
Biochemical pharmacology 2022 Mar;197:114932
Circular RNA PLCE1 promotes epithelial mesenchymal transformation, glycolysis in colorectal cancer and M2 polarization of tumor-associated macrophages.
Yi B, Dai K, Yan Z, Yin Z
Bioengineered 2022 Mar;13(3):6243-6256
Bioengineered 2022 Mar;13(3):6243-6256
Local delivery of naringin in beta-cyclodextrin modified mesoporous bioactive glass promotes bone regeneration: from anti-inflammatory to synergistic osteogenesis and osteoclastogenesis.
Mo Y, Zhao F, Lin Z, Cao X, Chen D, Chen X
Biomaterials science 2022 Mar 29;10(7):1697-1712
Biomaterials science 2022 Mar 29;10(7):1697-1712
Polymeric indoximod based prodrug nanoparticles with doxorubicin entrapment for inducing immunogenic cell death and improving the immunotherapy of breast cancer.
Zang X, Song J, Yi X, Piyu J
Journal of materials chemistry. B 2022 Mar 23;10(12):2019-2027
Journal of materials chemistry. B 2022 Mar 23;10(12):2019-2027
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
Wang G, Li X, Li N, Wang X, He S, Li W, Fan W, Li R, Liu J, Hou S
Redox biology 2022 Jun;52:102297
Redox biology 2022 Jun;52:102297
Mussel-inspired collagen-hyaluronic acid composite scaffold with excellent antioxidant properties and sustained release of a growth factor for enhancing diabetic wound healing.
Wang Y, Chen L, Ren DY, Feng ZX, Zhang LY, Zhong YF, Jin MY, Xu FW, Feng CY, Du YZ, Tan WQ
Materials today. Bio 2022 Jun;15:100320
Materials today. Bio 2022 Jun;15:100320
Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.
Xu L, Liu Y, Tang L, Xiao H, Yang Z, Wang S
International journal of molecular sciences 2022 Jun 3;23(11)
International journal of molecular sciences 2022 Jun 3;23(11)
Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32.
Yin J, Zeng H, Fan K, Xie H, Shao Y, Lu Y, Zhu J, Yao Z, Liu L, Zhang H, Luo B, Wang X, Zeng C, Bai X, Zhang H, Cai D
Cell death & disease 2022 Jun 24;13(6):567
Cell death & disease 2022 Jun 24;13(6):567
Implantation of a nerve protector embedded with human GMSC-derived Schwann-like cells accelerates regeneration of crush-injured rat sciatic nerves.
Zhang Q, Burrell JC, Zeng J, Motiwala FI, Shi S, Cullen DK, Le AD
Stem cell research & therapy 2022 Jun 20;13(1):263
Stem cell research & therapy 2022 Jun 20;13(1):263
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
Wang Y, Xie W, Feng Y, Xu Z, He Y, Xiong Y, Chen L, Li X, Liu J, Liu G, Wu Q
International journal of molecular medicine 2022 Jul;50(1)
International journal of molecular medicine 2022 Jul;50(1)
Human Neural Stem Cell Secretome Inhibits Lipopolysaccharide-Induced Neuroinflammation Through Modulating Microglia Polarization by Activating Peroxisome Proliferator-Activated Receptor Gamma.
Zhou J, Ni W, Ling Y, Lv X, Niu D, Zeng Y, Qiu Y, Si Y, Wang Z, Hu J
Stem cells and development 2022 Jul;31(13-14):369-382
Stem cells and development 2022 Jul;31(13-14):369-382
Electrospun nanoyarn and exosomes of adipose-derived stem cells for urethral regeneration: Evaluations in vitro and in vivo.
Wang L, Cheng W, Zhu J, Li W, Li D, Yang X, Zhao W, Ren M, Ren J, Mo X, Fu Q, Zhang K
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 2):112218
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 2):112218
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Wang X, Du H, Li X
International immunopharmacology 2022 Jan;102:108413
International immunopharmacology 2022 Jan;102:108413
Glutamine Antagonist Synergizes with Electrodynamic Therapy to Induce Tumor Regression and Systemic Antitumor Immunity.
Chen G, Xu Q, Feng Z, Xu Q, Zhang X, Yang Y, Zhang Y, Liang XJ, Yu Z, Yu M
ACS nano 2022 Jan 25;16(1):951-962
ACS nano 2022 Jan 25;16(1):951-962
Coal dust exposure triggers heterogeneity of transcriptional profiles in mouse pneumoconiosis and Vitamin D remedies.
Mu M, Li B, Zou Y, Wang W, Cao H, Zhang Y, Sun Q, Chen H, Ge D, Tao H, Hu D, Yuan L, Tao X, Wang J
Particle and fibre toxicology 2022 Jan 20;19(1):7
Particle and fibre toxicology 2022 Jan 20;19(1):7
Incorporation of magnesium oxide nanoparticles into electrospun membranes improves pro-angiogenic activity and promotes diabetic wound healing.
Liu M, Wang R, Liu J, Zhang W, Liu Z, Lou X, Nie H, Wang H, Mo X, Abd-Elhamid AI, Zheng R, Wu J
Biomaterials advances 2022 Feb;133:112609
Biomaterials advances 2022 Feb;133:112609
A Hierarchical-Structured Mineralized Nanofiber Scaffold with Osteoimmunomodulatory and Osteoinductive Functions for Enhanced Alveolar Bone Regeneration.
He Y, Tian M, Li X, Hou J, Chen S, Yang G, Liu X, Zhou S
Advanced healthcare materials 2022 Feb;11(3):e2102236
Advanced healthcare materials 2022 Feb;11(3):e2102236
Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target.
Abdelfattah N, Kumar P, Wang C, Leu JS, Flynn WF, Gao R, Baskin DS, Pichumani K, Ijare OB, Wood SL, Powell SZ, Haviland DL, Parker Kerrigan BC, Lang FF, Prabhu SS, Huntoon KM, Jiang W, Kim BYS, George J, Yun K
Nature communications 2022 Feb 9;13(1):767
Nature communications 2022 Feb 9;13(1):767
miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression.
Ma C, He D, Tian P, Wang Y, He Y, Wu Q, Jia Z, Zhang X, Zhang P, Ying H, Jin ZB, Hu G
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 8;119(6)
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 8;119(6)
Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy.
Zhu J, Guo M, Cui Y, Meng Y, Ding J, Zeng W, Zhou W
ACS applied materials & interfaces 2022 Feb 2;14(4):5090-5100
ACS applied materials & interfaces 2022 Feb 2;14(4):5090-5100
ALA-PDT regulates macrophage M1 polarization via ERK/MAPK-NLRP3 pathway to promote the early inflammatory response.
Wang L, Zhang W, Cen R, Yue C, Xiao T, Deng Y, Li L, Sun K, Lei X
Lasers in surgery and medicine 2022 Dec;54(10):1309-1320
Lasers in surgery and medicine 2022 Dec;54(10):1309-1320
Colchicine-Containing Nanoparticles Attenuates Acute Myocardial Infarction Injury by Inhibiting Inflammation.
Wang L, Peng Y, Song L, Xia D, Li C, Li Z, Li Q, Yu A, Lu C, Wang Y
Cardiovascular drugs and therapy 2022 Dec;36(6):1075-1089
Cardiovascular drugs and therapy 2022 Dec;36(6):1075-1089
Delivery of germacrone (GER) using macrophages-targeted polymeric nanoparticles and its application in rheumatoid arthritis.
Tan T, Huang Q, Chu W, Li B, Wu J, Xia Q, Cao X
Drug delivery 2022 Dec;29(1):692-701
Drug delivery 2022 Dec;29(1):692-701
Immunomodulatory effect and safety of TNF-α RNAi mediated by oral yeast microcapsules in rheumatoid arthritis therapy.
Hu N, Zhu L, Zhang L, Wang J, Wang Y, Luo J, He L, Hao Z, Zhang L
Materials today. Bio 2022 Dec;16:100384
Materials today. Bio 2022 Dec;16:100384
GABA regulates IL-1β production in macrophages.
Fu J, Han Z, Wu Z, Xia Y, Yang G, Yin Y, Ren W
Cell reports 2022 Dec 6;41(10):111770
Cell reports 2022 Dec 6;41(10):111770
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Yan J, Zhang Y, Wang L, Li Z, Tang S, Wang Y, Gu N, Sun X, Li L
Journal of neuroinflammation 2022 Dec 3;19(1):289
Journal of neuroinflammation 2022 Dec 3;19(1):289
Nicotinamide n-Oxide Attenuates HSV-1-Induced Microglial Inflammation through Sirtuin-1/NF-κB Signaling.
Song X, Cao W, Wang Z, Li F, Xiao J, Zeng Q, Wang Y, Li S, Ye C, Wang Y, Zheng K
International journal of molecular sciences 2022 Dec 16;23(24)
International journal of molecular sciences 2022 Dec 16;23(24)
Cell Infiltrative Inner Connected Porous Hydrogel Improves Neural Stem Cell Migration and Differentiation for Functional Repair of Spinal Cord Injury.
Shi M, Xu Q, Ding L, Xia Y, Zhang C, Lai H, Liu C, Deng DYB
ACS biomaterials science & engineering 2022 Dec 12;8(12):5307-5318
ACS biomaterials science & engineering 2022 Dec 12;8(12):5307-5318
Pro-efferocytic macrophage membrane biomimetic nanoparticles for the synergistic treatment of atherosclerosis via competition effect.
Sha X, Dai Y, Chong L, Wei M, Xing M, Zhang C, Li J
Journal of nanobiotechnology 2022 Dec 1;20(1):506
Journal of nanobiotechnology 2022 Dec 1;20(1):506
Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction.
Li H, Zhu J, Xu YW, Mou FF, Shan XL, Wang QL, Liu BN, Ning K, Liu JJ, Wang YC, Mi JX, Wei X, Shao SJ, Cui GH, Lu R, Guo HD
Redox biology 2022 Aug;54:102384
Redox biology 2022 Aug;54:102384
Microsphere-Gel Composite System with Mesenchymal Stem Cell Recruitment, Antibacterial, and Immunomodulatory Properties Promote Bone Regeneration via Sequential Release of LL37 and W9 Peptides.
Ma S, Wang C, Dong Y, Jing W, Wei P, Peng C, Liu Z, Zhao B, Wang Y
ACS applied materials & interfaces 2022 Aug 31;14(34):38525-38540
ACS applied materials & interfaces 2022 Aug 31;14(34):38525-38540
Artificial Intelligence-Assisted Bioinformatics, Microneedle, and Diabetic Wound Healing: A "New Deal" of an Old Drug.
Xue Y, Chen C, Tan R, Zhang J, Fang Q, Jin R, Mi X, Sun D, Xue Y, Wang Y, Xiong R, Lu H, Tan W
ACS applied materials & interfaces 2022 Aug 24;14(33):37396-37409
ACS applied materials & interfaces 2022 Aug 24;14(33):37396-37409
DNA Origami as a Nanomedicine for Targeted Rheumatoid Arthritis Therapy through Reactive Oxygen Species and Nitric Oxide Scavenging.
Ma Y, Lu Z, Jia B, Shi Y, Dong J, Jiang S, Li Z
ACS nano 2022 Aug 23;16(8):12520-12531
ACS nano 2022 Aug 23;16(8):12520-12531
Atractylenolide II inhibits tumor-associated macrophages (TAMs)-induced lung cancer cell metastasis.
Zhang Y, Liu Y, Wang J, Jiang Z, Zhang L, Cui Y, Zhao D, Wang Y
Immunopharmacology and immunotoxicology 2022 Apr;44(2):227-237
Immunopharmacology and immunotoxicology 2022 Apr;44(2):227-237
MEF2C promotes M1 macrophage polarization and Th1 responses.
Zhao X, Di Q, Liu H, Quan J, Ling J, Zhao Z, Xiao Y, Wu H, Wu Z, Song W, An H, Chen W
Cellular & molecular immunology 2022 Apr;19(4):540-553
Cellular & molecular immunology 2022 Apr;19(4):540-553
Two-stage degradation and novel functional endothelium characteristics of a 3-D printed bioresorbable scaffold.
Yin T, Du R, Wang Y, Huang J, Ge S, Huang Y, Tan Y, Liu Q, Chen Z, Feng H, Du J, Wang Y, Wang G
Bioactive materials 2022 Apr;10:378-396
Bioactive materials 2022 Apr;10:378-396
Zileuton, a 5-Lipoxygenase Inhibitor, Attenuates Haemolysate-Induced BV-2 Cell Activation by Suppressing the MyD88/NF-κB Pathway.
Su HY, Tsai YC, Tsai HP, Lin CL
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
Reactive oxygen species-degradable polythioketal urethane foam dressings to promote porcine skin wound repair.
Patil P, Russo KA, McCune JT, Pollins AC, Cottam MA, Dollinger BR, DeJulius CR, Gupta MK, D'Arcy R, Colazo JM, Yu F, Bezold MG, Martin JR, Cardwell NL, Davidson JM, Thompson CM, Barbul A, Hasty AH, Guelcher SA, Duvall CL
Science translational medicine 2022 Apr 20;14(641):eabm6586
Science translational medicine 2022 Apr 20;14(641):eabm6586
Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis.
Hu N, Zhang X, Zhang X, Guan Y, He R, Xue E, Zhang X, Deng W, Yu J, Wang W, Shi Q
Clinical science (London, England : 1979) 2022 Apr 14;136(7):455-471
Clinical science (London, England : 1979) 2022 Apr 14;136(7):455-471
Fe(III)-Chelated Polydopamine Nanoparticles for Synergistic Tumor Therapies of Enhanced Photothermal Ablation and Antitumor Immune Activation.
Xu N, Hu A, Pu X, Li J, Wang X, Wang J, Huang Z, Liao X, Yin G
ACS applied materials & interfaces 2022 Apr 13;14(14):15894-15910
ACS applied materials & interfaces 2022 Apr 13;14(14):15894-15910
Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma.
Zhao L, Zhang J, Xuan S, Liu Z, Wang Y, Zhao P
Frontiers in cell and developmental biology 2021;9:600506
Frontiers in cell and developmental biology 2021;9:600506
Inhibition of Sphingosine-1-Phosphate Receptor 2 Prevents Thoracic Aortic Dissection and Rupture.
Pan G, Liao M, Dai Y, Li Y, Yan X, Mai W, Liu J, Liao Y, Qiu Z, Zhou Z
Frontiers in cardiovascular medicine 2021;8:748486
Frontiers in cardiovascular medicine 2021;8:748486
Receptor-Interacting Protein Kinase 3 Inhibition Prevents Cadmium-Mediated Macrophage Polarization and Subsequent Atherosclerosis via Maintaining Mitochondrial Homeostasis.
Zhang J, Feng W, Li M, Chen P, Ning X, Ou C, Chen M
Frontiers in cardiovascular medicine 2021;8:737652
Frontiers in cardiovascular medicine 2021;8:737652
Sodium Lactate Accelerates M2 Macrophage Polarization and Improves Cardiac Function after Myocardial Infarction in Mice.
Zhang J, Huang F, Chen L, Li G, Lei W, Zhao J, Liao Y, Li Y, Li C, Chen M
Cardiovascular therapeutics 2021;2021:5530541
Cardiovascular therapeutics 2021;2021:5530541
lncRNA DCST1-AS1 Facilitates Oral Squamous Cell Carcinoma by Promoting M2 Macrophage Polarization through Activating NF-κB Signaling.
Ai Y, Liu S, Luo H, Wu S, Wei H, Tang Z, Li X, Zou C
Journal of immunology research 2021;2021:5524231
Journal of immunology research 2021;2021:5524231
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Zhu Q, Yuan J, He Y, Hu Y
Journal of oncology 2021;2021:5170496
Journal of oncology 2021;2021:5170496
Gastric Electrical Pacing Reduces Apoptosis of Interstitial Cells of Cajal via Antioxidative Stress Effect Attributing to Phenotypic Polarization of M2 Macrophages in Diabetic Rats.
Wang H, Zhao K, Ba Y, Gao T, Shi N, Niu Q, Liu C, Chen Y
Oxidative medicine and cellular longevity 2021;2021:1298657
Oxidative medicine and cellular longevity 2021;2021:1298657
FSTL3 is a Prognostic Biomarker in Gastric Cancer and is Correlated with M2 Macrophage Infiltration.
Liu YJ, Li JP, Zhang Y, Nie MJ, Zhang YH, Liu SL, Zou X
OncoTargets and therapy 2021;14:4099-4117
OncoTargets and therapy 2021;14:4099-4117
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
Lin X, Zhan J, Jiang J, Ren Y
Journal of inflammation research 2021;14:2061-2078
Journal of inflammation research 2021;14:2061-2078
LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient Prognosis.
Cen X, Huang Y, Lu Z, Shao W, Zhuo C, Bao C, Feng S, Wei C, Tang X, Cen L, Guo W, Tian X, Tang Q, Huang X
Cancer management and research 2021;13:5957-5968
Cancer management and research 2021;13:5957-5968
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Cui X, Qin T, Zhao Z, Yang G, Sanches JGP, Zhang Q, Fan S, Cao L, Hu X
Journal of Cancer 2021;12(15):4686-4697
Journal of Cancer 2021;12(15):4686-4697
Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages.
Jiang R, Xu J, Zhang Y, Zhu X, Liu J, Tan Y
Frontiers in pharmacology 2021;12:680512
Frontiers in pharmacology 2021;12:680512
Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.
Yang L, Dong Y, Wu C, Youngblood H, Li Y, Zong X, Li L, Xu T, Zhang Q
Theranostics 2021;11(3):1269-1294
Theranostics 2021;11(3):1269-1294
Identification of an Aging-Related Gene Signature in Predicting Prognosis and Indicating Tumor Immune Microenvironment in Breast Cancer.
Lv W, Zhao C, Tan Y, Hu W, Yu H, Zeng N, Zhang Q, Wu Y
Frontiers in oncology 2021;11:796555
Frontiers in oncology 2021;11:796555
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
Le F, Yang L, Han Y, Zhong Y, Zhan F, Feng Y, Hu H, Chen T, Tan B
Frontiers in oncology 2021;11:704001
Frontiers in oncology 2021;11:704001
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Yang Y, Yang Y, Chen M, Chen J, Wang J, Ma Y, Qian H
Biomaterials science 2021 Sep 28;9(19):6597-6608
Biomaterials science 2021 Sep 28;9(19):6597-6608
circ_C20orf11 enhances DDP resistance by inhibiting miR-527/YWHAZ through the promotion of extracellular vesicle-mediated macrophage M2 polarization in ovarian cancer.
Yin J, Huang HY, Long Y, Ma Y, Kamalibaike M, Dawuti R, Li L
Cancer biology & therapy 2021 Sep 2;22(7-9):440-454
Cancer biology & therapy 2021 Sep 2;22(7-9):440-454
Immunohistopathological Analysis of Immunoglobulin E-Positive Epidermal Dendritic Cells with House Dust Mite Antigens in Naturally Occurring Skin Lesions of Adult and Elderly Patients with Atopic Dermatitis.
Tanei R, Hasegawa Y
Dermatopathology (Basel, Switzerland) 2021 Sep 1;8(3):426-441
Dermatopathology (Basel, Switzerland) 2021 Sep 1;8(3):426-441
Bacterial navigation for tumor targeting and photothermally-triggered bacterial ghost transformation for spatiotemporal drug release.
Xie S, Zhang P, Zhang Z, Liu Y, Chen M, Li S, Li X
Acta biomaterialia 2021 Sep 1;131:172-184
Acta biomaterialia 2021 Sep 1;131:172-184
A novel mechanism of lung cancer inhibition by methionine enkephalin through remodeling the immune status of the tumor microenvironment.
Zhang S, Huang H, Handley M, Griffin N, Bai X, Shan F
International immunopharmacology 2021 Oct;99:107999
International immunopharmacology 2021 Oct;99:107999
peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm.
Mulorz J, Shayan M, Hu C, Alcazar C, Chan AHP, Briggs M, Wen Y, Walvekar AP, Ramasubramanian AK, Spin JM, Chen B, Tsao PS, Huang NF
Biomaterials science 2021 Oct 12;9(20):6903-6914
Biomaterials science 2021 Oct 12;9(20):6903-6914
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
A multi-channel collagen scaffold loaded with neural stem cells for the repair of spinal cord injury.
Liu S, Xie YY, Wang LD, Tai CX, Chen D, Mu D, Cui YY, Wang B
Neural regeneration research 2021 Nov;16(11):2284-2292
Neural regeneration research 2021 Nov;16(11):2284-2292
Glial cell line-derived neurotrophic factor ameliorates dextran sulfate sodium-induced colitis in mice via a macrophage-mediated pathway.
Zeng J, Yu H, Gan HT
International immunopharmacology 2021 Nov;100:108143
International immunopharmacology 2021 Nov;100:108143
Baihui (DU20)-penetrating-Qubin (GB7) acupuncture regulates microglia polarization through miR-34a-5p/Klf4 signaling in intracerebral hemorrhage rats.
Li D, Zhao Y, Bai P, Li Y, Wan S, Zhu X, Liu M
Experimental animals 2021 Nov 10;70(4):469-478
Experimental animals 2021 Nov 10;70(4):469-478
Intrauterine inflammation induced white matter injury protection by fibrinogen-like protein 2 deficiency in perinatal mice.
Zhan D, Zhang C, Long W, Wei L, Jin S, Du C, Li Z, Guo S, Huang L, Ning Q, Luo X
Pediatric research 2021 May;89(7):1706-1714
Pediatric research 2021 May;89(7):1706-1714
Tetramethylpyrazine Protects Blood-Spinal Cord Barrier Integrity by Modulating Microglia Polarization Through Activation of STAT3/SOCS3 and Inhibition of NF-кB Signaling Pathways in Experimental Autoimmune Encephalomyelitis Mice.
Zhang L, Lu X, Gong L, Cui L, Zhang H, Zhao W, Jiang P, Hou G, Hou Y
Cellular and molecular neurobiology 2021 May;41(4):717-731
Cellular and molecular neurobiology 2021 May;41(4):717-731
MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway.
Lu Y, Liu L, Pan J, Luo B, Zeng H, Shao Y, Zhang H, Guan H, Guo D, Zeng C, Zhang R, Bai X, Zhang H, Cai D
Cell death & disease 2021 May 25;12(6):533
Cell death & disease 2021 May 25;12(6):533
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca(2+)/CaMKII/Nrf2 signaling pathway.
Lv Z, Xu X, Sun Z, Yang YX, Guo H, Li J, Sun K, Wu R, Xu J, Jiang Q, Ikegawa S, Shi D
Cell death & disease 2021 May 18;12(6):504
Cell death & disease 2021 May 18;12(6):504
Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer.
Zhang GQ, Jiao Q, Shen CT, Song HJ, Zhang HZ, Qiu ZL, Luo QY
Cancer science 2021 Mar;112(3):997-1010
Cancer science 2021 Mar;112(3):997-1010
Chemokine-Induced PBMC and Subsequent MSC Migration Toward Decellularized Heart Valve Tissue.
VeDepo MC, Flores K, Jacot JG
Cardiovascular engineering and technology 2021 Jun;12(3):325-338
Cardiovascular engineering and technology 2021 Jun;12(3):325-338
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Liu X, Lv Z, Zhou S, Kan S, Liu X, Jing P, Xu W
International immunopharmacology 2021 Jul;96:107776
International immunopharmacology 2021 Jul;96:107776
Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization.
Ding J, Yang C, Cheng Y, Wang J, Zhang S, Yan S, He F, Yin T, Yang J
International immunopharmacology 2021 Jan;90:106788
International immunopharmacology 2021 Jan;90:106788
Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization.
Yang Y, Guo L, Wang Z, Liu P, Liu X, Ding J, Zhou W
Biomaterials 2021 Jan;264:120390
Biomaterials 2021 Jan;264:120390
Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization.
Zhou F, Wang X, Han B, Tang X, Liu R, Ji Q, Zhou Z, Zhang L
Molecular pain 2021 Jan-Dec;17:1744806921996520
Molecular pain 2021 Jan-Dec;17:1744806921996520
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8(+) T cell exclusion.
Fang W, Zhou T, Shi H, Yao M, Zhang D, Qian H, Zeng Q, Wang Y, Jin F, Chai C, Chen T
Journal of experimental & clinical cancer research : CR 2021 Jan 4;40(1):4
Journal of experimental & clinical cancer research : CR 2021 Jan 4;40(1):4
Eradicating intracellular MRSA via targeted delivery of lysostaphin and vancomycin with mannose-modified exosomes.
Yang X, Xie B, Peng H, Shi G, Sreenivas B, Guo J, Wang C, He Y
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:454-467
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:454-467
Chronic oral exposure to cadmium causes liver inflammation by NLRP3 inflammasome activation in pubertal mice.
Li X, Li H, Cai D, Li P, Jin J, Jiang X, Li Z, Tian L, Chen G, Sun J, Bai W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111944
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111944
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
Zhou W, Zhong Z, Lin D, Liu Z, Zhang Q, Xia H, Peng S, Liu A, Lu Z, Wang Y, Ye S, Ye Q
Cell death & disease 2021 Feb 24;12(2):211
Cell death & disease 2021 Feb 24;12(2):211
Preventive and Therapeutic Spermidine Treatment Attenuates Acute Colitis in Mice.
Ma L, Ni L, Yang T, Mao P, Huang X, Luo Y, Jiang Z, Hu L, Zhao Y, Fu Z, Ni Y
Journal of agricultural and food chemistry 2021 Feb 17;69(6):1864-1876
Journal of agricultural and food chemistry 2021 Feb 17;69(6):1864-1876
Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.
Huang Z, Li X, Zhou T, Jiang Y, Shi JH
Annals of translational medicine 2021 Dec;9(23):1719
Annals of translational medicine 2021 Dec;9(23):1719
MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis.
An L, Yin F
Tissue & cell 2021 Dec;73:101669
Tissue & cell 2021 Dec;73:101669
Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages.
Li C, Pan XY, Ma M, Zhao J, Zhao F, Lv YP
Pharmaceutical biology 2021 Dec;59(1):1533-1539
Pharmaceutical biology 2021 Dec;59(1):1533-1539
Multivalent effects of heptamannosylated β-cyclodextrins on macrophage polarization to accelerate wound healing.
Zhang YN, Zhao R, Cao J, Chen B, Luo D, Lu J, Iqbal MZ, Zhang Q, Kong X
Colloids and surfaces. B, Biointerfaces 2021 Dec;208:112071
Colloids and surfaces. B, Biointerfaces 2021 Dec;208:112071
Effective-compound combination inhibits the M2-like polarization of macrophages and attenuates the development of pulmonary fibrosis by increasing autophagy through mTOR signaling.
Zhao P, Cai Z, Tian Y, Li J, Li K, Li M, Bai Y, Li J
International immunopharmacology 2021 Dec;101(Pt B):108360
International immunopharmacology 2021 Dec;101(Pt B):108360
FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway.
Liu H, Wang M, Jin Z, Sun D, Zhu T, Liu X, Tan X, Shi G
Biochemical and biophysical research communications 2021 Dec 10;582:77-85
Biochemical and biophysical research communications 2021 Dec 10;582:77-85
The role of adenosine A(1) receptor in the peripheral tramadol's effect in the temporomandibular joint of rats.
Abdalla HB, Napimoga MH, de Macedo Maganin AG, Lopes AH, Cunha TM, Gill HS, Clemente-Napimoga JT
International immunopharmacology 2021 Aug;97:107680
International immunopharmacology 2021 Aug;97:107680
The impact of ExHp-CD (outer membrane vesicles) released from Helicobacter pylori SS1 on macrophage RAW 264.7 cells and their immunogenic potential.
Ahmed AAQ, Qi F, Zheng R, Xiao L, Abdalla AME, Mao L, Bakadia BM, Liu L, Atta OM, Li X, Shi Z, Yang G
Life sciences 2021 Aug 15;279:119644
Life sciences 2021 Aug 15;279:119644
Distinct phenotypic expression levels of macrophages in neonatal lungs.
Fang SY, Chen JL, Chiu MH, Huang CC, Lin MW, Lam CF
Experimental and therapeutic medicine 2021 Apr;21(4):369
Experimental and therapeutic medicine 2021 Apr;21(4):369
M2 Macrophage-Derived Exosomal miR-590-3p Attenuates DSS-Induced Mucosal Damage and Promotes Epithelial Repair via the LATS1/YAP/ β-Catenin Signalling Axis.
Deng F, Yan J, Lu J, Luo M, Xia P, Liu S, Wang X, Zhi F, Liu D
Journal of Crohn's & colitis 2021 Apr 6;15(4):665-677
Journal of Crohn's & colitis 2021 Apr 6;15(4):665-677
Deliver Anti-inflammatory Drug Baicalein to Macrophages by Using a Crystallization Strategy.
Zhang J, Teng C, Li C, He W
Frontiers in chemistry 2020;8:787
Frontiers in chemistry 2020;8:787
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Qi B, Yang C, Zhu Z, Chen H
Frontiers in cell and developmental biology 2020;8:574940
Frontiers in cell and developmental biology 2020;8:574940
Attenuation of Diabetic Nephropathy in Diabetic Mice by Fasudil through Regulation of Macrophage Polarization.
Xie F, Lei J, Ran M, Li Y, Deng L, Feng J, Zhong Y, Li J
Journal of diabetes research 2020;2020:4126913
Journal of diabetes research 2020;2020:4126913
Trichinella spiralis Thioredoxin Peroxidase 2 Regulates Protective Th2 Immune Response in Mice by Directly Inducing Alternatively Activated Macrophages.
Jin QW, Zhang NZ, Li WH, Qin HT, Liu YJ, Ohiolei JA, Niu DY, Yan HB, Li L, Jia WZ, Song MX, Fu BQ
Frontiers in immunology 2020;11:2015
Frontiers in immunology 2020;11:2015
Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.
Li Y, Zhai P, Zheng Y, Zhang J, Kellum JA, Peng Z
Frontiers in immunology 2020;11:1415
Frontiers in immunology 2020;11:1415
CyTOF Analysis Reveals a Distinct Immunosuppressive Microenvironment in IDH Mutant Anaplastic Gliomas.
Fu W, Wang W, Li H, Jiao Y, Weng J, Huo R, Yan Z, Wang J, Xu H, Wang S, Wang J, Chen D, Cao Y, Zhao J
Frontiers in oncology 2020;10:560211
Frontiers in oncology 2020;10:560211
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
Yan C, Ma Z, Ma H, Li Q, Zhai Q, Jiang T, Zhang Z, Wang Q
Molecular neurobiology 2020 Sep;57(9):3875-3890
Molecular neurobiology 2020 Sep;57(9):3875-3890
Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats.
Teixeira JM, Abdalla HB, Basting RT, Hammock BD, Napimoga MH, Clemente-Napimoga JT
International immunopharmacology 2020 Oct;87:106841
International immunopharmacology 2020 Oct;87:106841
hUC-MSCs ameliorated CUMS-induced depression by modulating complement C3 signaling-mediated microglial polarization during astrocyte-microglia crosstalk.
Li J, Wang H, Du C, Jin X, Geng Y, Han B, Ma Q, Li Q, Wang Q, Guo Y, Wang M, Yan B
Brain research bulletin 2020 Oct;163:109-119
Brain research bulletin 2020 Oct;163:109-119
Blocking P2X7-Mediated Macrophage Polarization Overcomes Treatment Resistance in Lung Cancer.
Qin J, Zhang X, Tan B, Zhang S, Yin C, Xue Q, Zhang Z, Ren H, Chen J, Liu M, Qian M, Du B
Cancer immunology research 2020 Nov;8(11):1426-1439
Cancer immunology research 2020 Nov;8(11):1426-1439
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Wang Y, Zhang H, Chen Q, Jiao F, Shi C, Pei M, Lv J, Zhang H, Wang L, Gong Z
Cell proliferation 2020 Jun;53(6):e12829
Cell proliferation 2020 Jun;53(6):e12829
Relationship of tumour-associated macrophages with poor prognosis in Wilms' tumour.
Tian K, Wang X, Wu Y, Wu X, Du G, Liu W, Wu R
Journal of pediatric urology 2020 Jun;16(3):376.e1-376.e8
Journal of pediatric urology 2020 Jun;16(3):376.e1-376.e8
ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses.
Qiu J, Peng P, Xin M, Wen Z, Chen Z, Lin S, Kuang M, Fu Y, Fang G, Li S, Li C, Mao J, Qin L, Ding Y
Biomaterials science 2020 Jun 7;8(11):3147-3163
Biomaterials science 2020 Jun 7;8(11):3147-3163
One-Step Large-Scale Nanotexturing of Nonplanar PTFE Surfaces to Induce Bactericidal and Anti-inflammatory Properties.
Xu J, Moon H, Xu J, Lim J, Fischer T, McNally HA, Sintim HO, Lee H
ACS applied materials & interfaces 2020 Jun 17;12(24):26893-26904
ACS applied materials & interfaces 2020 Jun 17;12(24):26893-26904
Macrophage Spheroids with Chronological Phenotype Shifting To Promote Therapeutic Angiogenesis in Critical Limb Ischemia.
Ran P, Chen W, Wei J, Qiu B, Chen M, Xie S, Li X
ACS applied bio materials 2020 Jun 15;3(6):3707-3717
ACS applied bio materials 2020 Jun 15;3(6):3707-3717
Myeloid-specific dopamine D(2) receptor signalling controls inflammation in acute pancreatitis via inhibiting M1 macrophage.
Han X, Ni J, Wu Z, Wu J, Li B, Ye X, Dai J, Chen C, Xue J, Wan R, Wen L, Wang X, Hu G
British journal of pharmacology 2020 Jul;177(13):2991-3008
British journal of pharmacology 2020 Jul;177(13):2991-3008
Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.
Weinstock NI, Shin D, Dhimal N, Hong X, Irons EE, Silvestri NJ, Reed CB, Nguyen D, Sampson O, Cheng YC, Lau JTY, Bongarzone ER, Kofler J, Escolar ML, Gelb MH, Wrabetz L, Feltri ML
Neuron 2020 Jul 8;107(1):65-81.e9
Neuron 2020 Jul 8;107(1):65-81.e9
TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages.
Liu Z, Xie Y, Xiong Y, Liu S, Qiu C, Zhu Z, Mao H, Yu M, Wang X
Cancer letters 2020 Jan 28;469:173-185
Cancer letters 2020 Jan 28;469:173-185
Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice.
Yin Y, Phạm TL, Shin J, Shin N, Kang DW, Lee SY, Lee W, Kim CS, Kim SR, Hong J, Kim DW
Journal of clinical medicine 2020 Jan 22;9(2)
Journal of clinical medicine 2020 Jan 22;9(2)
Dexmedetomidine Inhibits Neuroinflammation by Altering Microglial M1/M2 Polarization Through MAPK/ERK Pathway.
Qiu Z, Lu P, Wang K, Zhao X, Li Q, Wen J, Zhang H, Li R, Wei H, Lv Y, Zhang S, Zhang P
Neurochemical research 2020 Feb;45(2):345-353
Neurochemical research 2020 Feb;45(2):345-353
Quercetin Promotes Diabetic Wound Healing via Switching Macrophages From M1 to M2 Polarization.
Fu J, Huang J, Lin M, Xie T, You T
The Journal of surgical research 2020 Feb;246:213-223
The Journal of surgical research 2020 Feb;246:213-223
Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice.
Zhao P, Zhou W, Zhang Y, Li J, Zhao Y, Pan L, Shen Z, Chen W, Hui J
Journal of cellular and molecular medicine 2020 Feb;24(4):2593-2609
Journal of cellular and molecular medicine 2020 Feb;24(4):2593-2609
The effects of the M2a macrophage-induced axonal regeneration of neurons by arginase 1.
Zhang J, Li Y, Duan Z, Kang J, Chen K, Li G, Weng C, Zhang D, Zhang L, Wang J, Li B
Bioscience reports 2020 Feb 28;40(2)
Bioscience reports 2020 Feb 28;40(2)
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
Conlon TM, John-Schuster G, Heide D, Pfister D, Lehmann M, Hu Y, Ertüz Z, Lopez MA, Ansari M, Strunz M, Mayr C, Angelidis I, Ciminieri C, Costa R, Kohlhepp MS, Guillot A, Günes G, Jeridi A, Funk MC, Beroshvili G, Prokosch S, Hetzer J, Verleden SE, Alsafadi H, Lindner M, Burgstaller G, Becker L, Irmler M, Dudek M, Janzen J, Goffin E, Gosens R, Knolle P, Pirotte B, Stoeger T, Beckers J, Wagner D, Singh I, Theis FJ, de Angelis MH, O'Connor T, Tacke F, Boutros M, Dejardin E, Eickelberg O, Schiller HB, Königshoff M, Heikenwalder M, Yildirim AÖ
Nature 2020 Dec;588(7836):151-156
Nature 2020 Dec;588(7836):151-156
The role of CCR5 in the protective effect of Esculin on lipopolysaccharide-induced depressive symptom in mice.
Chen T, Zheng M, Li Y, Liu S, He L
Journal of affective disorders 2020 Dec 1;277:755-764
Journal of affective disorders 2020 Dec 1;277:755-764
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, Ding M, Zhao A, Yao W
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
C/EBP Homologous Protein (CHOP) Activates Macrophages and Promotes Liver Fibrosis in Schistosoma japonicum-Infected Mice.
Duan M, Yang Y, Peng S, Liu X, Zhong J, Guo Y, Lu M, Nie H, Ren B, Zhang X, Liu L
Journal of immunology research 2019;2019:5148575
Journal of immunology research 2019;2019:5148575
Electroacupuncture Pretreatment Alleviates Cerebral Ischemic Injury Through α7 Nicotinic Acetylcholine Receptor-Mediated Phenotypic Conversion of Microglia.
Ma Z, Zhang Z, Bai F, Jiang T, Yan C, Wang Q
Frontiers in cellular neuroscience 2019;13:537
Frontiers in cellular neuroscience 2019;13:537
Activation of β2-Adrenoceptor Attenuates Sepsis-Induced Hippocampus-Dependent Cognitive Impairments by Reversing Neuroinflammation and Synaptic Abnormalities.
Zong MM, Zhou ZQ, Ji MH, Jia M, Tang H, Yang JJ
Frontiers in cellular neuroscience 2019;13:293
Frontiers in cellular neuroscience 2019;13:293
Metformin induces the M2 macrophage polarization to accelerate the wound healing via regulating AMPK/mTOR/NLRP3 inflammasome singling pathway.
Qing L, Fu J, Wu P, Zhou Z, Yu F, Tang J
American journal of translational research 2019;11(2):655-668
American journal of translational research 2019;11(2):655-668
Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis.
Liu B, Huang B, Hu G, He D, Li Y, Ran X, Du J, Fu S, Liu D
Frontiers in immunology 2019;10:2650
Frontiers in immunology 2019;10:2650
Metformin ameliorates experimental diabetic periodontitis independently of mammalian target of rapamycin (mTOR) inhibition by reducing NIMA-related kinase 7 (Nek7) expression.
Zhou X, Zhang P, Wang Q, Ji N, Xia S, Ding Y, Wang Q
Journal of periodontology 2019 Sep;90(9):1032-1042
Journal of periodontology 2019 Sep;90(9):1032-1042
Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system.
Cui C, Xu P, Li G, Qiao Y, Han W, Geng C, Liao D, Yang M, Chen D, Jiang P
Redox biology 2019 Sep;26:101295
Redox biology 2019 Sep;26:101295
Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice.
Li Q, Liu B, Breitkopf-Heinlein K, Weng H, Jiang Q, Dong P, Dooley S, Xu K, Ding H
Molecular medicine reports 2019 Sep;20(3):2743-2753
Molecular medicine reports 2019 Sep;20(3):2743-2753
Baicalein administered in the subacute phase ameliorates ischemia-reperfusion-induced brain injury by reducing neuroinflammation and neuronal damage.
Yang S, Wang H, Yang Y, Wang R, Wang Y, Wu C, Du G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109102
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109102
Intestinal autophagy links psychosocial stress with gut microbiota to promote inflammatory bowel disease.
Wang SL, Shao BZ, Zhao SB, Chang X, Wang P, Miao CY, Li ZS, Bai Y
Cell death & disease 2019 Sep 30;10(6):391
Cell death & disease 2019 Sep 30;10(6):391
The enhanced effect and underlying mechanisms of mesenchymal stem cells with IL-33 overexpression on myocardial infarction.
Chen Y, Zuo J, Chen W, Yang Z, Zhang Y, Hua F, Shao L, Li J, Chen Y, Yu Y, Shen Z
Stem cell research & therapy 2019 Sep 23;10(1):295
Stem cell research & therapy 2019 Sep 23;10(1):295
NETs promote ALI/ARDS inflammation by regulating alveolar macrophage polarization.
Song C, Li H, Li Y, Dai M, Zhang L, Liu S, Tan H, Deng P, Liu J, Mao Z, Li Q, Su X, Long Y, Lin F, Zeng Y, Fan Y, Luo B, Hu C, Pan P
Experimental cell research 2019 Sep 15;382(2):111486
Experimental cell research 2019 Sep 15;382(2):111486
Aedes aegypti saliva impairs M1-associated proinflammatory phenotype without promoting or affecting M2 polarization of murine macrophages.
Barros MS, Lara PG, Fonseca MT, Moretti EH, Filgueiras LR, Martins JO, Capurro ML, Steiner AA, Sá-Nunes A
Parasites & vectors 2019 May 16;12(1):239
Parasites & vectors 2019 May 16;12(1):239
The effect of Jianpi Yangzheng Xiaozheng Decoction and its components on gastric cancer.
Wu J, Zhang XX, Zou X, Wang M, Wang HX, Wang YH, Li CY, Zhao LG, Chen M, Pei LX, Liu SL, Sun QM
Journal of ethnopharmacology 2019 May 10;235:56-64
Journal of ethnopharmacology 2019 May 10;235:56-64
Oral squamous cell carcinoma-derived exosomes promote M2 subtype macrophage polarization mediated by exosome-enclosed miR-29a-3p.
Cai J, Qiao B, Gao N, Lin N, He W
American journal of physiology. Cell physiology 2019 May 1;316(5):C731-C740
American journal of physiology. Cell physiology 2019 May 1;316(5):C731-C740
Inhibition of MicroRNA-9-5p Protects Against Cardiac Remodeling Following Myocardial Infarction in Mice.
Xiao Y, Zhang Y, Chen Y, Li J, Zhang Z, Sun Y, Shen H, Zhao Z, Huang Z, Zhang W, Chen W, Shen Z
Human gene therapy 2019 Mar;30(3):286-301
Human gene therapy 2019 Mar;30(3):286-301
PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.
Li Y, Zhou H, Li Y, Han L, Song M, Chen F, Shang G, Wang D, Wang Z, Zhang W, Zhong M
Journal of cellular and molecular medicine 2019 Jun;23(6):4179-4195
Journal of cellular and molecular medicine 2019 Jun;23(6):4179-4195
Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice.
Cheng H, Qi T, Zhang X, Kong Q, Min X, Mao Q, Cao X, Liu L, Ding Z
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1451-1459
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1451-1459
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, Zhu M, Zhou M, Yang M, Mu M, Chen W, Zhou B, Zhang J, Tang K
Cell proliferation 2019 Jul;52(4):e12650
Cell proliferation 2019 Jul;52(4):e12650
Trichosanthes kirilowii lectin ameliorates streptozocin-induced kidney injury via modulation of the balance between M1/M2 phenotype macrophage.
Jiandong L, Yang Y, Peng J, Xiang M, Wang D, Xiong G, Li S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:93-102
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:93-102
HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization.
Kong Q, Li N, Cheng H, Zhang X, Cao X, Qi T, Dai L, Zhang Z, Chen X, Li C, Li Y, Xue B, Fang L, Liu L, Ding Z
Diabetes 2019 Feb;68(2):361-376
Diabetes 2019 Feb;68(2):361-376
Mesenchymal stem cells attenuate sepsis-induced liver injury via inhibiting M1 polarization of Kupffer cells.
Liang X, Li T, Zhou Q, Pi S, Li Y, Chen X, Weng Z, Li H, Zhao Y, Wang H, Chen Y
Molecular and cellular biochemistry 2019 Feb;452(1-2):187-197
Molecular and cellular biochemistry 2019 Feb;452(1-2):187-197
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
Gou Y, Li X, Li P, Zhang H, Xu T, Wang H, Wang B, Ma X, Jiang X, Zhang Z
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658
Protective Effects of Live Combined B. subtilis and E. faecium in Polymicrobial Sepsis Through Modulating Activation and Transformation of Macrophages and Mast Cells.
Guo L, Meng M, Wei Y, Lin F, Jiang Y, Cui X, Wang G, Wang C, Guo X
Frontiers in pharmacology 2018;9:1506
Frontiers in pharmacology 2018;9:1506
Burn wounds in the young versus the aged patient display differential immunological responses.
Farinas AF, Bamba R, Pollins AC, Cardwell NL, Nanney LB, Thayer WP
Burns : journal of the International Society for Burn Injuries 2018 Sep;44(6):1475-1481
Burns : journal of the International Society for Burn Injuries 2018 Sep;44(6):1475-1481
Effects of exposure of adult mice to multi-walled carbon nanotubes on the liver lipid metabolism of their offspring.
Zhang HY, Chen RL, Shao Y, Wang HL, Liu ZG
Toxicology research 2018 Sep 1;7(5):809-816
Toxicology research 2018 Sep 1;7(5):809-816
Proteomic profile in the mussel Perna viridis after short-term exposure to the brown tide alga Aureococcus anophagefferens.
Zheng JW, Liu SL, Lu SH, Li HY, Liu JS, Yang WD
Ecotoxicology and environmental safety 2018 Oct 30;162:365-375
Ecotoxicology and environmental safety 2018 Oct 30;162:365-375
Prolonged release of bone morphogenetic protein-2 in vivo by gene transfection with DNA-functionalized calcium phosphate nanoparticle-loaded collagen scaffolds.
Tenkumo T, Vanegas Sáenz JR, Nakamura K, Shimizu Y, Sokolova V, Epple M, Kamano Y, Egusa H, Sugaya T, Sasaki K
Materials science & engineering. C, Materials for biological applications 2018 Nov 1;92:172-183
Materials science & engineering. C, Materials for biological applications 2018 Nov 1;92:172-183
Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects.
Lin T, Liu S, Chen S, Qiu S, Rao Z, Liu J, Zhu S, Yan L, Mao H, Zhu Q, Quan D, Liu X
Acta biomaterialia 2018 Jun;73:326-338
Acta biomaterialia 2018 Jun;73:326-338
Exosomal MALAT1 derived from oxidized low-density lipoprotein-treated endothelial cells promotes M2 macrophage polarization.
Huang C, Han J, Wu Y, Li S, Wang Q, Lin W, Zhu J
Molecular medicine reports 2018 Jul;18(1):509-515
Molecular medicine reports 2018 Jul;18(1):509-515
ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration.
Li Y, Xie Y, Hao J, Liu J, Ning Y, Tang Q, Ma M, Zhou H, Guan S, Zhou Q, Lv X
Experimental cell research 2018 Jul 15;368(2):167-173
Experimental cell research 2018 Jul 15;368(2):167-173
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Inhibition of HMGB1 mediates neuroprotection of traumatic brain injury by modulating the microglia/macrophage polarization.
Gao T, Chen Z, Chen H, Yuan H, Wang Y, Peng X, Wei C, Yang J, Xu C
Biochemical and biophysical research communications 2018 Feb 26;497(1):430-436
Biochemical and biophysical research communications 2018 Feb 26;497(1):430-436
Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis.
Li YQ, Chen YF, Dang YP, Wang Y, Shang ZZ, Ma Q, Wang YJ, Zhang J, Luo L, Li QQ, Zhao L
Frontiers in cellular and infection microbiology 2017;7:443
Frontiers in cellular and infection microbiology 2017;7:443
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Lu Y, Dong Y, Tucker D, Wang R, Ahmed ME, Brann D, Zhang Q
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Characteristics and potential role of M2 macrophages in COPD.
He S, Xie L, Lu J, Sun S
International journal of chronic obstructive pulmonary disease 2017;12:3029-3039
International journal of chronic obstructive pulmonary disease 2017;12:3029-3039
Spared Nerve Injury Increases the Expression of Microglia M1 Markers in the Prefrontal Cortex of Rats and Provokes Depression-Like Behaviors.
Xu N, Tang XH, Pan W, Xie ZM, Zhang GF, Ji MH, Yang JJ, Zhou MT, Zhou ZQ
Frontiers in neuroscience 2017;11:209
Frontiers in neuroscience 2017;11:209
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Ren X, Fu X, Zhang X, Chen S, Huang S, Yao L, Liu G
Biochemical pharmacology 2017 Sep 15;140:73-88
Biochemical pharmacology 2017 Sep 15;140:73-88
Interleukin-17A-promoted MSC2 polarization related with new bone formation of ankylosing spondylitis.
He T, Huang Y, Zhang C, Liu D, Cheng C, Xu W, Zhang X
Oncotarget 2017 Nov 14;8(57):96993-97008
Oncotarget 2017 Nov 14;8(57):96993-97008
PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice.
Lu J, Xie L, Liu C, Zhang Q, Sun S
Scandinavian journal of immunology 2017 Jun;85(6):395-405
Scandinavian journal of immunology 2017 Jun;85(6):395-405
Sevoflurane preconditioning protects from posttransplant injury in mouse lung transplantation.
Yamada Y, Laube I, Jang JH, Bonvini JM, Inci I, Weder W, Beck Schimmer B, Jungraithmayr W
The Journal of surgical research 2017 Jun 15;214:270-277
The Journal of surgical research 2017 Jun 15;214:270-277
(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway.
Zhang X, Xu F, Liu L, Feng L, Wu X, Shen Y, Sun Y, Wu X, Xu Q
International immunopharmacology 2017 Dec;53:1-10
International immunopharmacology 2017 Dec;53:1-10
Alternatively Activated (M2) Macrophage Phenotype Is Inducible by Endothelin-1 in Cultured Human Macrophages.
Soldano S, Pizzorni C, Paolino S, Trombetta AC, Montagna P, Brizzolara R, Ruaro B, Sulli A, Cutolo M
PloS one 2016;11(11):e0166433
PloS one 2016;11(11):e0166433
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model.
Du P, Ma Q, Zhu ZD, Li G, Wang Y, Li QQ, Chen YF, Shang ZZ, Zhang J, Zhao L
European journal of pharmacology 2016 Dec 15;793:119-126
European journal of pharmacology 2016 Dec 15;793:119-126
CD26 costimulatory blockade improves lung allograft rejection and is associated with enhanced interleukin-10 expression.
Yamada Y, Jang JH, De Meester I, Baerts L, Vliegen G, Inci I, Yoshino I, Weder W, Jungraithmayr W
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2016 Apr;35(4):508-17
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2016 Apr;35(4):508-17
Curcumin induces M2 macrophage polarization by secretion IL-4 and/or IL-13.
Gao S, Zhou J, Liu N, Wang L, Gao Q, Wu Y, Zhao Q, Liu P, Wang S, Liu Y, Guo N, Shen Y, Wu Y, Yuan Z
Journal of molecular and cellular cardiology 2015 Aug;85:131-9
Journal of molecular and cellular cardiology 2015 Aug;85:131-9
Granulomas are a source of interleukin-33 expression in pulmonary and extrapulmonary sarcoidosis.
Kempf W, Zollinger T, Sachs M, Ullmer E, Cathomas G, Dirnhofer S, Mertz KD
Human pathology 2014 Nov;45(11):2202-10
Human pathology 2014 Nov;45(11):2202-10
Metabolic and immunomodulatory effects of n-3 fatty acids are different in mesenteric and epididymal adipose tissue of diet-induced obese mice.
Ludwig T, Worsch S, Heikenwalder M, Daniel H, Hauner H, Bader BL
American journal of physiology. Endocrinology and metabolism 2013 Jun 1;304(11):E1140-56
American journal of physiology. Endocrinology and metabolism 2013 Jun 1;304(11):E1140-56
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 18704-1-AP(MRC1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 18704-1-AP(MRC1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 18704-1-AP(MRC1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD206 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CD206. This antibody recognizes human, mouse antigen. The CD206 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
